Hormesis, Brain Aging and Metabolism, Volume 295 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Aging and brain metabolism, Calorie restriction: brain physiological and biological aspects, Intermittent fasting and ketone bodies, Physical exercise and brain health: running x sedentary lifestyle, Phytochemicals and brain health, Environmental enrichment and neuroplasticity, Hormesis and brain disease, Neuroinflammation and hormesis, and more.Additional chapters cover Glucocorticoids and Neuroinflammation and Hormesis and cancer.
Advances in Parasitology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
Artificial Intelligence Strategies for Early Intervention in Neurodegeneration addresses the challenges surrounding the implementation of AI-based diagnoses of neurological disorders. These challenges include the lack of large, high-quality datasets, the necessity for standardization of data collection and analysis protocols, technical hurdles in developing accurate and reliable AI algorithms, and the requirement for regulatory approval and integration into clinical workflows. The book's content provides guidance to researchers on how to develop and integrate AI algorithms and biomarker analysis into their workflow, leading to a significant change in disease diagnosis.These techniques involve the analysis of physiological signals and images to identify patterns associated with specific diseases, and how AI algorithms can analyze medical imagery and movement and speech patterns to identify early signs of neurodegenerative diseases.
Sterility, Sterilisation and Sterility Assurance for Pharmaceuticals: Technology, Validation and Current Regulations, Second Edition is a comprehensive guide that navigates the complex world of pharmaceutical sterilisation. This new edition is updated to reflect the latest standards and regulations, ensuring the book remains aligned with current approaches. The book also explores emerging sterilisation methods, providing readers with the most up-to-date techniques in the field. Additionally, the inclusion of new case studies offers practical examples that aid in the understanding and application of these sterilisation methods. The failure to control any microbial challenge within a process or product can lead to a contaminated marketed product, potentially causing harm to patients. Hence, sterilisation is of critical importance to healthcare and the manufacturing of medical devices and pharmaceuticals. This edition covers a wide range of topics including sterility, sterilisation and microorganisms, pyrogenicity and bacterial endotoxins, regulatory requirements and good manufacturing practices, and different sterilisation methods such as gamma radiation, e-beam, dry heat, steam, gas, vapour, filtration, and new sterilisation techniques. It provides a thorough examination of sterilisation technology and the biopharmaceutical manufacturing process, including aseptic filling, container and packaging design, and cleanroom environments. The new edition also introduces substantial additions such as X-ray sterilization, liquid-phase sterilization, ultraviolet light, supercritical gases, and sterilisation assurance governance. Each chapter has been updated to reflect the latest changes in the field. "Sterility, Sterilisation and Sterility Assurance for Pharmaceuticals: Technology, Validation and Current Regulations" is an indispensable resource for those involved in the manufacturing of sterile products. Its comprehensive coverage of sterilisation methods, combined with practical case studies, provides readers with a robust understanding of sterilisation technology and its application. The book will be of great value to those in pharmaceuticals, healthcare, and medical device manufacturing, providing them with the knowledge to ensure their products are safe and compliant with current standards and regulations.
Heavy Metal Toxicity and Neurodegeneration delves into the intricate relationship between heavy metals and neurodegenerative diseases. It synthesizes and presents the latest research findings, shedding light on the mechanisms by which heavy metals cause neuronal damage and contribute to disease progression. By integrating various perspectives and collating diverse studies, this book serves as an invaluable resource for those seeking to understand the profound impact of heavy metals on neurological health. In addition to detailing the mechanisms involved, the book highlights the importance of early detection and preventive measures.It caters to researchers, clinicians, policymakers, and students, offering a comprehensive and accessible overview that bridges the gap between theory and practical application. This scholarly work is poised to inform and guide future research and policy decisions in the field of neurodegenerative disease.
Preventable Medical Errors: The Role of Different Sciences in Medical Education and Practice addresses the issues of staying up to date with evolving medical practices, by providing practical examples linked to real-world patient safety concerns and illustrating theoretical discussions with clear clinical practice scenarios. The book is divided into two sections, Part 1 - How Did It Come To This? and Part 2 - Where Does It Go From Here?; which guide the reader through how we got here historically and how we can navigate our way out using the tools the author presents. Thus paving the way, bridging a gap between theory and practice, while emphasizing the importance of patient safety. Written for all medical professionals, at the forefront of postmodern and scientific medical advancements, to ultimately improve clinical outcomes and reduce preventable medical errors.
Rhizosphere Revelations: Microbial Strategies for Sustainable Agriculture, Volume 116 in the Advances in Botanical Research series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Plant-Microbe Partnerships: Symbiotic Secrets of the Rhizosphere, The role of rhizosphere microbes in phosphorus mineralization and acquisition, Microbial Contributions to Soil Carbon Sequestration, Role of Mycorrhizal Fungi in Nutrient Cycling, Bioremediation Potential of Rhizosphere Microbes, Rhizosphere Remedies: Harnessing AMF for Disease Management, and Genetic Engineering of Rhizosphere Microbes.
The ACC series explores physiologic and pathophysiologic biochemistry in general and Clinical Chemistry specifically. Complex molecular pathways are elucidated using historical, current and emerging technologies such as biosensor design, metabolomics and proteomics. Identification of novel biomarkers and accurate and precise analysis are fundamental to cutting-edge personalized medicine and treatment. Predictive biomarkers that enable the development of new detection and intervention strategies early in disease are especially important given the aging worldwide population.
Computational Biomechanics of Human Joints delves into the intricate details of each joint, exploring anatomical, mechanical, pathological, and therapeutic aspects. The book offers a comprehensive understanding of joint biomechanics by dedicating each chapter to specific joints, detailing their anatomical structure, biomechanical mechanisms, associated diseases, and pathologies. It also covers treatments, surgical interventions, and imaging-based modeling alongside numerical simulation techniques using the finite element method. This approach provides readers with an innovative perspective on the technological advancements in joint biomechanics. In addition to exploring joint-specific details, the book discusses the advantages and limitations of modern techniques.Finally, the book emphasizes the potential for these methods to improve clinical decision-making, optimize personalized treatments, and design medical devices. The integration of advanced modeling and simulation techniques enhances the understanding of the complex mechanisms of joints, contributing significantly to both academic research and practical clinical applications.
Quantum Health AI: The Revolution of Medicine, Public Health, and Global Health is the first comprehensive book defining the transformation of the global health ecosystem by the fusion of our most powerful technologies—quantum computing and artificial intelligence—while defending an actionable human-centred approach to doing so responsibly, equitably, and sustainably. We can continue to watch wars, diseases, poverty, polarization, cyber-crime, and climate change only worsen. Our strongest technologies can remain centralized in a small number of companies and countries for their profit and power. Or we can cooperatively put quantum AI to work for the health of all of us, by better managing this technology’s overarching strategic competition between democracies and autocracies, along with the public and private sectors (balancing human security with national security, economic growth with household livelihoods, individual rights with the common good). This book draws on the decade plus of original research and first-hand perspective of the world’s first triple doctorate-trained physician-data scientist and AI ethicist. It unpacks the history, science, values, and political economics framing and driving quantum AI (including its physics, metaphysics, ethics, governance, computing, sensing, communication, materials, and security), the global health ecosystem (healthcare systems, public health agencies, biotechnology companies, and development institutions), and their growing integration, wins, and challenges. This one-stop book provides a global, inclusive, and practical guide for understanding and shaping these societal and technological trends. It thus empowers health, technology, and policy students, practitioners, professionals, researchers, and leaders in organizations, universities, companies, and governments—ultimately to make and maintain the human-centred quantum AI safeguarding and advancing humanity’s health, home, and future.