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Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

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Immune Cells and Cytokines in Cancer

  • 1st Edition
  • July 1, 2026
  • Bhalchandra Mirlekar
  • English
“Immune Cells and Cytokines in Cancer: A Therapeutic Perspective” highlights the recent trends in the field of cancer immunology by focusing on the functions of immune cells and cytokines in the initiation and metastasis of different solid and hematological malignancies. This title illustrates the cellular and molecular mechanisms associated with the immune cell-cytokines-tumor cells crosstalk axis and deciphers implications of immune cells, their receptors, and cytokines as therapeutic regimens for the treatment of cancer patients. Comprised of three sections, the book first illustrates the different immune cells involved in tumorigenesis, tumor-infiltrated immune cells, and their roles in modulating tumor contexture and growth. The second section deciphers the importance and functions of cytokines and how they modulate the tumor microenvironment by regulating immune cells associated with cancer. The final section reviews how targeting immune cells and cytokines is beneficial and discusses implications in cancer treatment. Researchers and clinicians interested in the fields of immunology, cancer biology, and oncology will benefit from this important and thorough resource.

Endotoxin in Critical Illness

  • 1st Edition
  • January 1, 2026
  • John Kellum + 1 more
  • English
“Endotoxin in Critical Illness” intricately explores the theme of endotoxin and sepsis through the lenses of basic, clinical, and translational science. This work consolidates and synthesizes novel clinical insights and groundbreaking scientific discoveries into one comprehensive resource on endotoxic septic shock and sheds light on cutting-edge approaches in treatment. Beginning with a historical journey, the book traces the evolution of understanding from ancient concepts to modern molecular insights. It covers the physiological aspects of endotoxin sensitivity, tolerance, and human response variation. The crucial role of the gut microbiome in critical illness serves as a translational link between foundational science and clinical implications, and the complex language of bacterial communication is introduced, merging basic science with potential translational applications. In the clinical arena, chapters cover the critical role of endotoxin in septic shock, trauma, and its relevance in COVID-19, providing a translational bridge between laboratory findings and real-world clinical scenarios. The historical context of anti-endotoxin drug development is revisited, emphasizing the translational challenges faced in bridging basic science discoveries to clinical applications. The discussion on quantifying endotoxin concentration as well as the exploration of therapeutic rationale and clinical experiences with endotoxin removal therapy serve as a culmination of basic understanding translated into practical applications. The book concludes by contemplating the complexity of sepsis and acknowledging the challenges in achieving personalized medicine and underscoring the dynamic nature of the translational journey. In essence, this comprehensive exploration provides clinicians, researchers, and scientists with a holistic understanding of endotoxin and sepsis and potential advancements in patient care.

Systemic Lupus Erythematosus

  • 3rd Edition
  • January 1, 2026
  • George C. Tsokos
  • English
“Systemic Lupus Erythematosus: Basic, Applied and Clinical Aspects” has been an essential resource for scientists and clinicians in this field since its original publication in 2015. The third edition of this work has been completely updated and expanded with the latest scientific and clinical developments in Systemic Lupus Erythematosus (SLE) to date. Contributors at the forefront of each topic come together to enhance content on epidemiology and diagnosis, pathogenesis, mechanisms of tissue damage, clinical aspects of the disease, antiphospholipid syndrome, and treatments. Also added is the latest information on new treatments, criteria, monogenic forms of lupus, insights on the role of microbiome, and advances in understanding disease pathogenesis. This must-have reference is an indispensable resource for specialists in the diagnosis and management of patients with SLE as well as early career or experienced investigators studying basic aspects of the disease. It is a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a key reference work for hospital libraries.

Encyclopedia of Immunobiology

  • 2nd Edition
  • September 1, 2025
  • Paul Kaye
  • English
The immune system is complex, multi-layered and has evolved throughout the development of invertebrate and vertebrate species to be able to sense the difference between "self" and foreign pathogens. A functioning immune system provides protection against bacterial, viral and parasitic infections; on the other hand, dysregulation of the immune system can result in a wide range of clinically important diseases including autoimmunity, allergies and inflammatory disorders. Understanding of the immune system has led to the development of a broad range of therapeutic interventions of fundamental importance to improve human health. Encyclopedia of Immunobiology covers the full range of Immunology, presenting topics in a logical, ordered way, and making extensive use of "hot links" to refer the reader to related content. The new edition is more than a simple updating of content from the original title. Fields such as immunotherapy, immunity to viral infection, vaccine development, inflammatory responses and the role of high throughput analyses are greatly expanded to reflect current and future trends in Immunology. This new edition plays a major role in bringing these concepts to the fore in a logical and coherent way, with the goal of integrating this information into the big picture.

The Immunology of the Domestic Ruminants

  • 1st Edition
  • September 1, 2025
  • Ian R Tizard
  • English
“The Immunology of the Domestic Ruminants” is a comprehensive examination of the biology of the domestic bovine immune systems. It discusses the normal functioning of the immune system in addition to its roles in resistance to infectious and parasitic diseases, as well as other pathological conditions such as chronic inflammatory and immunodeficiency diseases, making use of new data from the bovine genome project as well as any significant breed differences. Encompassing both innate and adaptive immunity, the book systematically covers both the basic and applied aspects of bovine immunology. The immunology of the major bacterial, viral, and parasitic diseases of cattle are described and explained. It also thoroughly reviews bovine vaccines as well as the critical role nutrition plays on the health of the ruminant immune system. Professionals in large animal research and practice will appreciate complete information on all aspects of domestic cattle, sheep and goat immunology in one essential resource.

Immunogenetics: A Molecular and Clinical Overview, Vol. 3

  • 1st Edition
  • July 7, 2025
  • Shafat Ali + 3 more
  • English
Immunogenetics: A Molecular and Clinical Overview, Vol. 3, Immune Cells and Immunotherapeutics in Recurrent Miscarriage provides an overview of the scientific knowledge, achievements, and findings in the field of immunogenetics of recurrent pregnancy loss. With a strong focus on the role immune cells can play in recurrent pregnancy loss, the book also examines immune therapeutic aspects. In fifteen chapters, the book describes the roles of both helper cells, nature killer cells, lymphoid cells, regulatory cells and macrophages in recurrent pregnancy loss. In addition, it describes clinical outcomes of several therapies and gives insight into new treatments. This new release is a valuable resource for health professionals, scientists and researchers, and all those who wish to broaden their knowledge in the allied field.

Immunogenetics: A Molecular and Clinical Overview

  • 1st Edition
  • July 7, 2025
  • Shafat Ali + 3 more
  • English
Immunogenetics: A Molecular and Clinical Overview: Immunogenetic Factors and Signaling Pathways in Recurrent Miscarriage, Volume Four provides an overview of the scientific knowledge, achievements, and findings in the field of immunogenetics of recurrent pregnancy loss. With a strong focus on the role immune cells can play in recurrent pregnancy loss, the book also examines immune therapeutic aspects. In seventeen chapters, the book describes the roles of several different signaling pathways and the role of JLA and microRNAs in recurrent pregnancy loss. Several chapters are dedicated to the role autoimmune antibodies play in recurrent pregnancy loss. This book is a valuable resource for health professionals, scientists, researchers, and all those who wish to broaden their knowledge in the allied field.

Cellular and Molecular Immunology

  • 11th Edition
  • June 30, 2025
  • Abul K. Abbas + 3 more
  • English
Well-written, readable, and superbly illustrated, Cellular and Molecular Immunology, 11th Edition, continues the tradition of excellence established through multiple editions of this bestselling text. Offering an unparalleled introduction to this complex field, it retains a practical, clinical focus while updating and revising all content to ensure clarity and comprehension, bringing readers fully up to date with new and emerging information in this challenging area. It's an ideal resource for medical, graduate, and undergraduate students, as well as a trusted reference for physicians and scientists.

Mitochondrial Signaling and Regulation

  • 1st Edition
  • June 1, 2025
  • Seyyed Shamsadin Athari + 1 more
  • English
"Mitochondrial Signaling and Regulation: Immune Responses and Diseases" summarizes the latest research on new molecular pathophysiology mechanisms and cell signaling pathways in pathogenesis of diseases via mitochondrial regulation. Early chapters in the book are devoted to mitochondria crucial role, regulation, and crosstalk. Subsequent chapters examine mitochondria mutations and mitochondria-related diseases, and final chapters discuss mitochondria and immune responses as well as mitochondria and allegro-inflammation. The use of biotechnology for the development of new treatments and targeted therapies against mitochondrial dysfunction is presented. Scientists and researchers alike will find value in this important resource, as it sets the foundation for the development of new classifications, prevention methods, therapies, and treatments of mitochondria-related diseases.