Reetika Mahajan, Faheem Shehjar, Sajad Majeed Zargar + 2 more
September 1, 2024
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Role of Medicinal Plants in Autoimmune Diseases: Concepts, Perspectives, and Utilization provides comprehensive knowledge of autoimmune diseases and the role of various medicinal plant products in their treatment. The book discusses the immune system as a group of complex biological structures and processes in an organism which gives protection against a wide range of pathogenic organisms while simultaneously distinguishing these pathogens from the organism’s own healthy cells and tissues, thus maintaining homeostasis in the body.It has been an age-old practice to use extracts and other parts of various plants in treating many diseases. Several plants contain various pharmacologically active substances which can be used to treat different diseases. Among these medicinal plants, many have shown good immunomodulatory properties and could act as natural immunosuppressant agents in treating autoimmune disorders.
Macrophages Biology and Tissue Inflammation in Health and Disease outlines the important role of macrophages—keys cells in the innate immune system—as regulators and orchestrators of inflammation and repair in health and disease. It contains chapters by leading authors on the basic and translational aspects of macrophage biology, covering how to maintained tissue homeostatis and how to deal with internal and external biological threats.
Microbes, Microbial Metabolism and Mucosal Immunity: An Overview presents a concise and well-vetted treatise on the study of microbiome and microbial metabolites. This volume is up-to-date with the most recent developments from the last decade. It encompasses the interaction of immunity and microbes — and their metabolites — from different mucosal organs including eye, skin, gastrointestinal system, lung, intestine, and cervix. Along with the efficiency of the immune system in inhibiting the growth and proliferation of microbes, the volume discusses how the mediators of the immune system can be targeted to develop therapies.This book presents the latest methods, gives broad and systematic coverage of most mucosal systems and diseases, and takes a fresh perspective that looks at the functional aspects of change in the microbiome. The study of microbiome and microbial metabolites and their roles in host mucosal immunology is a rapidly developing area of research. One major way in which the microbiome influences the host is through altered metabolism. Metabolites, readily available to the host, engender significant consequences. Microbial metabolites have been shown to impact the disease processes in both proximal and distal organs, including the brain in several neurocognitive disorders.
The Immunology of the Cat makes available the first single-source, comprehensive review of the feline immune system, reporting on all immunologic aspects of diseases of the cat and its relatives and relating recent basic science to important clinical issues. The book opens with the evolution, domestication, and development of the cat then provides detailed information on immunity to infectious diseases, feline allergic diseases, the top feline autoimmune diseases, and feline immunodeficiencies. Content examines feline vaccines, hypersensitivity, cancer, nutrition, and the aged cat. Professionals in veterinary research and practice will appreciate complete information on all aspects of feline immunology in one essential resource.
Immunotoxicogenomics: A Multidisciplinary Approach in Systems Toxicology covers the major mechanisms and effects of toxic substances on the immune system, and on the regulation of gene expression. This includes the aims, opportunities, clinical applications, recent developments, and emerging and future trends. The book begins with a discussion of the systemic approach to toxicants, but also looks at current genomic tools used to assess immunotoxicity and systems biology methods used in immuno-toxicogenomics. Other topics include genomic expression profiling, gene expression as a tool to understand and predict immunotoxicity, immunotox-icogenomics as a screening tool, and the assessment and analysis of Immunotoxicogenomics data.This book provides a collaborative, multidisciplinary approach for researchers in the fields of toxicology, genetics, immunology, and others engaged in the study on the effects of toxic substances on immune responses.
The Rose-Mackay Textbook of Autoimmune Diseases, Seventh Edition is a comprehensive reference that emphasizes the "3 P’s" of 21st Century medicine: precision, prediction, and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients.This new edition continues its success with 75% of the content revised, updated, or completely new. This edition is a valuable resource to clinicians involved in the diagnosis and treatment of autoimmune disease, as well as to scientists who want to follow developments in the field.
Paul B. Fisher, O. John Semmes, Julius O. Nyalwidhe + 1 more
July 1, 2024
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Current Status of Prostate Cancer: Diagnosis, Biomarkers and Therapies, Volume 161 in the Advances in Cancer Research series, covers timely topics such as The Prostate Cancer Tissue N-glycome as a Source of Biomarkers, a Progression from Normal to Metastatic Disease, Multiplexed Targeted Proteomics for Prostate Cancer Biomarker Verification, MRI for the Detection of Clinically Significant Prostate Cancer: Update and Future Directions, Genetic and epigenetic factors for prostate cancer progression, Epigenetic regulation of androgen dependent and independent prostate cancer, Molecular Landscape of Prostate Cancer Bone Metastasis, Future of radioligand Therapy in PC, and more.Additional chapters of note include Advancements in Computer Vision and Pathology: Unraveling the Potential of Artificial Intelligence for Precision Diagnosis and Beyond and Extracellular Vesicles in Prostate Cancer.
Regulatory T Cells and Autoimmune Diseases addresses recent findings concerning the role of Tregs in the pathogenesis of autoimmune diseases as well as their therapeutic applications. In particular, this book deals with various Treg-based mechanisms that can lead to autoimmune disease and covers different aspects linking Tregs with autoimmune mechanisms involved in disease development by discussing animal models and human studies.This book specifically focuses on Treg-based therapeutics and their targets to manage all known autoimmune rheumatic, central nervous system, bowel, liver, thyroid, kidney, myopathic, skin, blood and blood vessel, and eye diseases and aims to provide a must-have reference for designing therapeutic strategies to treat these autoimmune diseases. Additionally, this book covers vaccine-induced effects on the functioning of Tregs and development of CAR Treg therapy for autoimmune diseases and concludes with current challenges and future prospects of Treg-based therapeutics. This book is carefully designed to meet the requirements of both basic and advanced researchers in the area and provide new dimensions and insight into regulatory T cells’ role in autoimmune disease pathogenesis and therapy.