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Books in Applied immunology

Comorbidities in Inflammatory Arthritis

  • 1st Edition
  • Volume TBD
  • April 1, 2025
  • Fabiola Atzeni + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 3 7 2 2 - 5
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 3 7 2 3 - 2
During the last years, there is an increase of field knowledge on a number of comorbidities and extra-articular manifestations (EAMs) associated with inflammatory arthritis. Many adults suffering from inflammatory arthritis also have other chronic conditions, so early detection is key to a patient’s quality of life and survivability outcomes. Comorbidities and Extra-articular Manifestations in Inflammatory Arthritis, the 18th volume in Elsevier’s Handbook for Systemic Autoimmune Diseases series, provides a comprehensive review of the latest research on various comorbidities and EAMs associated with inflammatory arthritis.The book chapters review comorbidities and extra-articular manifestations in early and late disease stages, mechanisms involved in comorbidities development, as well as the impact of new treatment strategies specific to inflammatory arthritis and cardiovascular disease, metabolic syndrome, metabolic bone, infection, neoplasia, respiratory, gastrointestinal, kidney, mental health disease, and neurological disease. This book serves as an ideal reference for researchers and clinicians focused on inflammatory arthritis and related diseases.

Role of Medicinal Plants in Autoimmune Diseases

  • 1st Edition
  • October 25, 2024
  • Reetika Mahajan + 4 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 8 7 7 6 - 6
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 8 7 7 7 - 3
Role of Medicinal Plants in Autoimmune Diseases: Concepts, Perspectives, and Utilization provides comprehensive knowledge of autoimmune diseases and the role of various medicinal plant products in their treatment. The book discusses the immune system as a group of complex biological structures and processes in an organism which gives protection against a wide range of pathogenic organisms while simultaneously distinguishing these pathogens from the organism’s own healthy cells and tissues, thus maintaining homeostasis in the body.It has been an age-old practice to use extracts and other parts of various plants in treating many diseases. Several plants contain various pharmacologically active substances which can be used to treat different diseases. Among these medicinal plants, many have shown good immunomodulatory properties and could act as natural immunosuppressant agents in treating autoimmune disorders.

Cytokine Response Against Major Human Viral Infections

  • 1st Edition
  • October 22, 2024
  • Mukesh Samant + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 2 8 3 - 2
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 2 8 2 - 5
Cytokine Response Against Major Human Viral Infections provides in-depth coverage of the immunological response against human viral infections and the role and impact of cytokines on disease pathogenesis and host immune response.Cytokines, as a part of innate immunity, initiate the development of antiviral and TH 1-type immune responses. Cytokines also affect the adaptive immune response and disease manifestation. In five sections, this book gives a comprehensive introduction to the clinical manifestations of viral and infectious diseases; details the role of cytokines in DNA virus infections, RNA virus infections, and reverse transcribing virus infections; and gives insights into the recent advances and strategies in diagnostic tools and therapeutic and prophylactic measures.Cytokine Response Against Major Human Viral Infections is valuable resource for both researchers in immunology and virology, as well as for those in the biotech and pharmaceutical industries, engaged in the study of cytokines and their immunological response against human viral infections.

A New Era in Alzheimer's Research

  • 1st Edition
  • October 17, 2024
  • Sandeep Kumar Singh + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 5 4 0 - 6
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 5 3 9 - 0
A New Era in Alzheimer's Research: Pathogenesis, Prevention, and Treatment is focused on the research and perspectives in Alzheimer's disease (AD), offering an update on the challenging aspects of neurodegenerative disorders. Each chapter of this book contains unique and valuable scientific information on the latest progress of research in neurodevelopmental diseases. Even after years of research, Alzheimer's disease is still far from being cured; this book addresses the most current issues within the many dimensions relevant to the pathogenesis, diagnosis, and prevention under one cover, making it useful for researchers, students, and clinicians, as well as those in pharmaceuticals.

Macrophages Biology and Tissue Inflammation in Health and Disease

  • 1st Edition
  • June 26, 2024
  • Stuart Goodman + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 1 7 5 4 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 1 7 6 2 - 7
Macrophages Biology and Tissue Inflammation in Health and Disease outlines the important role of macrophages—keys cells in the innate immune system—as regulators and orchestrators of inflammation and repair in health and disease. It contains chapters by leading authors on the basic and translational aspects of macrophage biology, covering how to maintained tissue homeostatis and how to deal with internal and external biological threats.

Advanced Vaccination Technologies for Infectious and Chronic Diseases

  • 1st Edition
  • March 25, 2024
  • Vasso Apostolopoulos + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 8 5 6 4 - 9
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 8 5 6 5 - 6
Advanced Vaccination Technologies for Infectious and Chronic Diseases is a comprehensive guide that delves into the intricate details of vaccine design, development across various platforms, and the path to commercialization. This book provides an introductory overview of vaccines, covering various types, developmental methodologies, delivery systems, adjuvants, immunization, and measurement of vaccine efficacy. It also showcases examples of vaccine research efforts targeting infectious diseases, autoimmune disorders, and cancer. The book concludes by exploring cutting-edge advances in proteogenomics, immunopeptidomics, and future vaccine technologies.The primary objective of this book is to inform a broad scientific audience about the fundamental concepts underlying vaccine and immunology. Further, it serves as an invaluable reference for understanding the critical steps in the journey from discovery to regulatory processes for human clinical trials, addressing common misconceptions and presenting factual information about vaccinations. Advanced Vaccination Technologies for Infectious and Chronic Diseases is a requisite reference for occupational health professionals whose roles involve supervision of immunization programs such as those working within the National Health Service, some sectors of higher education, or the pharmaceutical industry. It also caters to those researchers engaged in vaccine development and all who want to learn the processes involved from laboratory research to final product.

Nanomedicine in Cancer Immunotherapy

  • 1st Edition
  • January 11, 2024
  • Prashant Kesharwani
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 8 7 7 0 - 4
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 8 7 7 1 - 1
Nanomedicine in Cancer Immunotherapy bridges the two disciplines of nanotechnology and immunology, summarizing the latest research into novel cancer treatments, often personalized to the patient. The book covers a wide range of nanomaterial types for use in cancer immunotherapy, including hydrogel, lipid, exosome, gold and peptide nanoparticles. The preparation, application, pros and cons of each nanomaterial class is reviewed, helping the reader understand the potential for each to tailor their own selections. Nanovaccines are also covered, along with a clinical evaluation and market analysis of nanomedicines for immunotherapy, offering an important clinical and commercial overview of this rapidly developing field.This book is an interesting reference for those working in the fields of nanotechnology, immunology, and cancer therapeutics, as well as clinicians with an interest in novel nano-based cancer treatments.

In Silico Approach Towards Magnetic Fluid Hyperthermia of Cancer Treatment

  • 1st Edition
  • February 28, 2023
  • Muhammad Suleman
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 3 2 8 6 - 5
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 3 2 8 7 - 2
In Silico Approach Towards Magnetic Fluid Hyperthermia in Cancer Treatment: Modeling and Simulation presents mathematical modeling and simulation approaches contrary to costly and time consuming in-vivo and in-vitro studies. Finite element method-based models of all hyperthermia processes of liver, brain and breast tumors are simulated on COMSOL Multiphysics software. Problems of constant versus variable heat sources, the backflow problem, the enhanced permeation and retention effect, the flow around Happel’s sphere in cells model structure, the deformation effect in poroelastic brain tumor, 3D flow through porous tissue, the reacting nanofluid flows, and optimization of parameters have been simulated for quantitative analysis. This important reference aids in hyperthermia treatment planning in clinical applications and provides an important compendium for practitioners as well as non-medical practicing scientists and engineers and is resource for both research and medical practice in hyperthermia treatment planning in clinical applications.

Comparative Mammalian Immunology

  • 1st Edition
  • February 9, 2023
  • Ian R Tizard
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 5 2 1 9 - 4
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 5 2 2 0 - 0
Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals provides a review on the current knowledge of mammalian immune systems from a comparative viewpoint. This reference encompasses recent work on the immune systems of marine mammals, bats and marsupials in addition to other lesser-known species, with the immune systems of humans and laboratory mice as components of chapters on primates and rodents respectively. The book also makes use of the most recent studies on the genomic sequences of the mammals to identify both common and unique features of each mammal's immune system. The book elucidates the complex, but coordinated and controlled series of interactions involving cells and molecules that has evolved to protect the host against disease. Mammals consist of a highly diverse group of animals in which the immune system has been subjected to a variety of selective pressures. This is reflected in differences in the organization and function of their immune systems, and is especially seen in those gene families characterized by complexity and polymorphism.

System Vaccinology

  • 1st Edition
  • August 20, 2022
  • Vijay Kumar Prajapati
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 8 5 9 4 1 - 7
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 9 7 8 6 - 0
Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials. My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines. This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens. Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters.

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