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Elsevier

Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Self-Learning AI in Healthcare

    Agentic Systems for Smarter Medicine
    • 1st Edition
    • Rajesh Kumar Dhanaraj + 4 more
    • English
    Self-Learning AI in Healthcare: Agentic Systems for Smarter Medicine covers the transformative potential of advanced artificial intelligence within modern medicine. The book addresses the critical need for self-learning and agentic AI systems that autonomously adapt, refine decision-making, and navigate complex clinical environments with minimal intervention. Chapters provide foundational insights into the rise of self-learning AI and neural networks tailored for adaptive medical systems. Subsequent chapters delve into unsupervised, semi-supervised, and reinforcement learning for autonomous healthcare decision-making, alongside decentralized edge AI approaches. Specialized sections cover personalized medicine, hospital workflow optimization, remote patient monitoring, early disease detection, federated learning for privacy preservation, and more.Further, this book explores AI applications in drug discovery, mental health support, radiology, digital twins, and medical robotics, culminating with an examination of future challenges, ethics, and regulatory frameworks shaping self-learning AI’s trajectory in healthcare. It is tailored to serve a diverse yet specialized audience spanning academic, professional, and research sectors. Healthcare IT professionals and clinical informatics specialists will gain practical guidance for implementing adaptive AI solutions within complex healthcare environments. AI researchers and data scientists focused on developing self-learning models will find cutting-edge methodologies and case studies that advance medical applications.

  • Thiamine Pyrophosphate (TPP)-Dependent Enzymes

    • 1st Edition
    • Volume 736
    • English
    Methods in Enzymology: Thiamine pyrophosphate-depend... enzymes Thiamine pyrophosphate (TPP)-dependent enzymes are a diverse group of ubiquitous enzymes. They have in common the use of the biologically active form of vitamin B1 as a cofactor, which gives them the ability to catalyze the formation or cleavage of carbon-sulfur, carbon-oxygen, carbon-nitrogen, and especially carbon-carbon bonds. The specific characteristics of TPP-dependent enzymes, related to both the chemistry of thiamine pyrophosphate and their organization into multimeric subunits, have always aroused the interest of scientists. During these last years they developed original experimental approaches, and also new analytical tools to study, understand and modulate the activity of these enzymes. In the first section of this volume, we propose to address a wide range of methods related to TPP-dependent enzymes as target in health and agrochemistry. Then in a second section, we will focus more particularly on TPP-dependent enzymes in biocatalysis, and in particular on the associated techniques in the field of enzymatic engineering and repurposing. In a third section, we will then address an exciting topic, namely that of the assimilation of one-carbon compounds such as formaldehyde. We will see how TPP enzymes are a tool of choice in biotechnology to address this issue. Finally, we will focus on dual cofactor TPP-dependent enzymes and multi-enzyme complexes using structural and metabolic approaches.

  • Gender Affirming Hormone Therapy in Humans

    Evidence from Murine Models
    • 1st Edition
    • Jeffrey David Zajac
    • English
    Gender Affirming Hormone Therapy in Humans: Evidence from Murine Models is an unprecedented reference for scientists, researchers, students and anyone interested in this field of research. The book is a review of the current state of mouse animal models of relevance to transgender health. It's divided into chapters specific for different tissues in which mouse models are described and their relevance to human health is discussed. This is a novel reference summarizing what these models demonstrate about the benefits and risks of GAHT and the most effective and lowest risk approach to treatment. The models suggest applications of this research to human studies and treatment of transgender people. There is an expanding number of transgender people with are few evidence based books that address this field relating to the importance and growing role of murine models.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 137
    • English
    Advances in Applied Microbiology presents the latest developments and innovative research in applied microbiology, covering topics such as microbial biotechnology, environmental applications, industrial processes, and medical advancements. It offers valuable insights into the practical uses of microorganisms in solving real-world challenges, making it an essential resource for researchers, professionals, and students in microbiology and related fields.

  • Biosimilars in Cancer

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Biosimilars in Cancer is a comprehensive resource addressing the role of biosimilars in treating various cancer types. This book offers a succinct yet thorough overview of current trends in oncology, covering 21 different cancers from liver to breast cancer. Each chapter provides detailed insights into the latest trends, fundamental facts, and practical and clinical data, making it an invaluable tool for academics and practitioners. By compiling this rich content into a single, accessible volume, the book empowers researchers and clinicians to enhance their understanding, and improve patient outcomes through the effective use of biosimilars in oncology. Targeted primarily at pharmaceutical researchers, biomedical scientists, and clinicians, Biosimilars in Cancer supports the growing oncology biosimilars market. It also provides critical insights for those involved in cancer diagnostics and clinical trials, helping them stay ahead in this rapidly progressing field.

  • Diabetic Neuropathy

    • 1st Edition
    • Shahidul Islam
    • English
    "Recent Therapeutic Targets for the Prevention and Management of Diabetic Complications: Neuropathy" covers recent research and therapeutic approaches of this diabetic complication for the management of diabetes. It is a detailed reference to understand the pathogenesis of diabetes to alleviate the overall complications of neuropathy to improve patient care. It is uniquely focused on the different aspects of neuropathy with a focus on the molecular and biological pathways (therapeutic target) to detect an early diagnosis to better manage the disease and improve patient care. The book is useful to anyone in the field particularly those who do research investigations, and day-to-day practice in the area of diabetes.

  • The Metabolon

    • 1st Edition
    • Volume 739
    • English
    Methods in Enzymology series: The Metabolon, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Cell Death Part F

    • 1st Edition
    • Volume 211
    • English
    Cell Death: Part F, Volume 211 presents the latest advances and comprehensive reviews in the rapidly evolving field of cell death. This volume explores the molecular mechanisms, regulatory pathways, and biological consequences of various forms of cell death—including apoptosis, necrosis, autophagy, and other non-canonical processes. Chapters in this new release include Flow cytometry analysis of mitochondrial apoptotic priming with BH3 profiling on senescent cells, Methods to study PIDDOsome and caspase 2 signaling, Isolation, characterization, and experimental applications of apoptotic bodies in vitro, Lipid ROS Measurement by Spectral Flow Cytometry based on the ratiometric dye BODIPYTM C11 581/591, and much more.Additional chapters cover CRISPR-Cas9 Screen to Identify Genes Regulating Cell Death, Flow cytometry-assisted discrimination of early apoptotic, late apoptotic and primary necrotic morphological markers in Saccharomyces cerevisiae, Cytofluorometric analysis of cell death in primary human neutrophils, Real-time tracking of cell death in human intestinal organoids: a quantitative imaging approach, and more.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 44
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 44 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Animal Models of Disease Part F

    • 1st Edition
    • Volume 211
    • English
    Animal Models of Disease, Part F, Volume 212 in the Methods in Cell Biology series, presents significant advancements in understanding disease mechanisms through animal models. The book features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

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