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Books in Molecular biology cellular biology and genetics

This collection offers insights into gene expression, cell signalling, and genetic regulation. Supporting researchers, clinicians, and students, it features advanced techniques, genetic engineering, and disease mechanisms, fostering innovations in personalized medicine, regenerative therapies, and molecular diagnostics.

  • PACAP

    From Discovery to Function
    • 1st Edition
    • David Vaudry + 1 more
    • English
    PACAP: From Discovery to Function in Health and Disease serves as a comprehensive review covering all aspects of PACAP and its receptors, from expression to function in healthy tissues and disease models. The book introduces the biochemical, pharmacological and signaling properties of PACAP before exploring the biological actions of PACAP in normal health and pathological conditions. It considers PACAP in relation to various aspects, including pain, stress, brain injury, tumor cells and neurodegenerative disease. Effect on peripheral organs is also covered, from the gastrointestinal tract and cardiovascular system to immune cells and bones, among others. Therapeutic potential is also explored. This is a volume in the Molecular Mediators in Health and Disease book series, and provides a complete analysis of PACAP and the latest research in the field. Thus it is an ideal guide for researchers interested in PACAP and its impact across health and disease.

  • Radiation Biology

    Molecular Foundations and Clinical Applications
    • 1st Edition
    • Barry S. Rosenstein + 1 more
    • English
    Radiation Biology: Molecular Foundations and Clinical Applications is a comprehensive exploration of the effects of radiation on living organisms, delving into the molecular mechanisms underlying cellular responses. This book examines critical topics such as radiation-induced DNA damage, repair processes, and molecular signaling pathways. It provides a detailed look at how cells respond to radiation, addressing cell cycle control, apoptosis, and the effects of radiation on immune system functionality. As a resource for researchers, it bridges the gap between molecular biology and clinical oncology, offering insights into radiation's role in both therapeutic contexts and its broader impact on human biology.In addition to its focus on molecular responses, the book covers topics like tumor microenvironment and metabolism, the role of epigenetics in radiation biology, and the hallmarks of cancer relevant to radiation therapy. It also provides discussions on chemotherapeutic agents, radiation carcinogenesis, and the complex interplay between radiation and cancer biology. The later sections extend the scope to tissue, organ, and systemic effects of radiation, making it an invaluable reference for professionals in molecular biology, oncology, and related fields striving to push the boundaries of radiation research.

  • Medical and Health Genomics of South Asia

    • 1st Edition
    • Dhavendra Kumar + 1 more
    • English
    Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region.Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

  • Non-Invasive Prenatal Screening of Rare Fetal Genetic Diseases

    • 1st Edition
    • Riyaz Ahmad Rather
    • English
    Non-Invasive Prenatal Screening of Rare Fetal Genetic Diseases offers a comprehensive exploration of the latest advancements in non-invasive prenatal screening (NIPS) technologies and their application in detecting rare fetal genetic disorders. It provides a detailed overview of current methods in NIPS technology, the application of NIPS in detecting rare genetic disorders, and ethical considerations. Sections cover advanced genomic methods such as Next-Generation Sequencing, Single-Nucleotide Polymorphism analysis, and Comparative Genomic Hybridization, highlighting their impact on the accuracy and scope of NIPS, while also exploring specific genetic disorders, including Trisomy 18, Trisomy 13, Duchenne Muscular Dystrophy, Angelman Syndrome, Turner Syndrome, and Cri du Chat Syndrome.Researchers will find this to be a valuable resource for understanding and applying NIPS protocols in their work, while clinicians will benefit from practical insights on appropriate screening methods, interpreting NIPS results, and counseling expectant parents. This book is an essential resource for researchers in obstetrics and gynecology, genetic counselors, and professionals in the biotechnology and pharmaceutical industries. It equips readers with the knowledge and tools needed to advance their work and improve prenatal care practices.

  • Artificial Intelligence Based Primary Care

    Artificial Intelligence and Human Cognition in General Practice and Family Medicine
    • 1st Edition
    • Anthony C. Chang + 5 more
    • English
    Artificial Intelligence Based Primary Care: Artificial Intelligence and Human Cognition in General Practice and Family Medicine provides a comprehensive look into the integration of artificial intelligence within primary care. This book aims to bridge the gap between data scientists and primary care clinicians by presenting potential AI applications, implementation challenges, and real-world clinical scenarios in an accessible manner. Comprised of 5 sections and 20 chapters, it offers both theoretical insights and practical guidance for family medicine practitioners.Additi... the book includes a chapter dedicated to a day in the life of a General Practitioner, showcasing the practical impact of AI. It also features an extra compendium listing the Top 100 articles and best books on Artificial Intelligence. This resource is invaluable for academics, researchers, and clinicians eager to expand their knowledge in this emerging field.

  • Advances in Biomedical Engineering - Part A

    • 1st Edition
    • Volume 402
    • English
    Advances in Biomedical Engineering, Part A, Volume 402 provides a comprehensive overview of the latest developments, innovations, and research in the rapidly evolving field of biomedical engineering. This book covers a broad spectrum of topics, including medical imaging, biomaterials, tissue engineering, biomechanics, bioinstrumentation, and healthcare technologies. Specific chapters include Advances in biomedical engineering, Recent advances in nanomedicine as drug delivery systems, Advances in Nano biomaterials for Biomedical Engineering, Neurodiagnostic: Advances in diagnostic tools, Advances in Ferroptosis Research and Application, Bioink-based 3D Bioprinting: Paving the Path for Regenerative Medicine, and MRI Acute/Sub-Acute Ischemic Stroke Segmentation with Deep Learning: A Comprehensive Review.

  • Ion Channels in Cellular Pathophysiology Part A

    • 1st Edition
    • Volume 97
    • English
    Ion Channels in Cellular Pathophysiology, Part A, Volume 97 in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Possible therapeutic effects of essential oils on Na channels in experimental diabetic neuropathy, Modulation of ion channels by Group I metabotropic glutamate receptors, ATP-sensitive potassium channels in neurons: roles in and beyond metabolic control, Chemically induced cardiotoxicity: role of voltage dependent ion channels, Thyroid Hormone Deficiency-Induced Cardiac Ion Channel Dysfunction: Molecular Mechanisms and Arrhythmic Implications, and much more.Additional chapters discuss Pathophysiological Insights into Ion Channel Dysregulation and Electrical Remodeling in Cardiac Cells During Trypanosoma cruzi Infection, Targeting Sodium Channels in Neuroblastoma: Implications for Cellular Physiology, Breast cancer and voltage ion channels, Alpha-helical charged peptides a new concept of NaV gating modifiers, Nerve electrophysiological alterations in experimental diabetic neuropathy, and Cardioprotective effect of natural products on doxorubicin-induced acute cardiotoxicity and cardiac ischemia-reperfusion injury.

  • Transposable Elements in Health and Disease

    • 1st Edition
    • Volume 116
    • English
    Transposable Elements in Health and Disease, Volume 116 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting comprehensive chapters on a variety of timely topics. Specific chapters examine Transposable Elements in Human Cancer: Regulation, Activation, and Genomic Consequences, Retrotransposons as both “architects” and “saboteurs” in the nervous system, Shaping Mammalian Genomes: The Regulation and Co-option of Transposable Elements, Transposable element analysis in -omics data, and Transposable elements in Aging: from biomarkers to effectors.Together, these contributions provide valuable insights into the mechanisms and impacts of transposable element activity, advancing our understanding of their broad significance in genetics, development, health, and disease.

  • Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer

    • 1st Edition
    • Afsar Naqvi + 1 more
    • English
    Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer explores the critical role of noncoding RNAs in immune-mediated diseases and cancers, providing an essential resource on their diagnostic and therapeutic potential. The book contributes valuable insights into the pathobiology of noncoding RNAs and their application in various diseases, delving into the latest research on noncoding RNAs, including their mechanisms, interactions, and roles in disease. In addition, it examines how noncoding RNAs influence immune responses, inflammation, and cancer progression. With a focus on both diagnostic and therapeutic applications, this book highlights the potential of noncoding RNAs as biomarkers and therapeutic targets. Across comprehensive chapters, the book covers a wide range of topics, including the role of virus-encoded microRNAs in immune evasion, the therapeutic aspects of non-coding RNA in hepatocellular carcinoma, the impact of microRNAs in periodontal inflammation, and the involvement of miRNAs and lncRNAs in regulating the tumor microenvironment in HCC. Other chapters explore the functions and clinical value of tumor-derived exosomes and miRNAs in cancer immune response, the interaction of noncoding RNA in cancer metastasis, and a panorama of non‐coding RNA in prostate cancer. This book is an invaluable resource for basic science researchers in the noncoding RNA field, cancer biologists, immunologists and RNA biologists interested in the latest advancements in noncoding RNA research.

  • Cryo-EM Methods and Management

    • 1st Edition
    • Edward T. Eng + 2 more
    • English
    Cryo-EM Methods and Management provides a detailed introduction to the latest advances of cryo-EM, from technical innovations to the logistical challenges of maintaining a modern cryo-EM facility. The book consists of four parts, beginning with an overview of cryo-EM. It then moves on to discuss Cryo-EM workflows, with chapters focusing on sample handling and preparation, data collection and hardware, and data procession and visualization. The third part centers on aspects of cryo-EM infrastructure and community building, considering facility set-up and management, monitoring facility performance, instrumentation monitoring , data sharing and standards, and training and development standards. The book then closes with a section looking towards future prospects for cryo-EM. This is an ideal reference for cryo-EM facility and lab managers, providing guidance to the often-overlooked aspect of facility building and management. Additionally researchers working with cryo-EM across molecular biology, structural biology, cell biology and biochemistry will benefit from this book.

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