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Books in Molecular biology cellular biology and genetics

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Cell Culture Techniques

  • 1st Edition
  • January 1, 2025
  • Shailendra Singh Shera
  • English
  • Paperback
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  • eBook
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Cell Culture Techniques: Protocols, Methods, Tools and Processes is the ideal laboratory reference to execute animal cell culture assays. Based on the author’s experience and practice, the selected methods represent the current status of the field. Cell culture practices covered in this book include the ones used both in academic and corporate lab setting.The initial part of the book guides the reader through the key decisions and challenges involved with setting up a cell culture laboratory. Serum-free media is then discussed as the way to provide cells the requirements for their growth. The next group of chapters cover the general procedures for cell culture, including selection of media, preparation and sterilization of equipment, tissue extraction or dissociation and initiation of the cell culture. The author then moves on to cover cell counting methods, cell proliferation assays, and scaling up animal cell culture. The chapters that follow discuss authentication, contamination detection by microbes and viruses. The next chapters cover stem cells, organoids, and spheroid cells. The last part of the book provides methods for cell separation, high-speed cell sorting, detection of cell cycle stages and then finally discusses biosafety aspects of cell culture.Providing readers a collection of over 50 animal cell culture laboratory methods, Cell Culture Techniques: Protocols, Methods, Tools and Processes is the ideal companion to bioscientists involved in animal research in academic settings and also to corporate based researchers looking for protocols, methods, tools and processes to improve their practice.

Molecular Medicine and Biomedical Research in the Era of Precision Medicine

  • 1st Edition
  • January 1, 2025
  • Ranbir Chander Sobti + 4 more
  • English
  • Paperback
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  • eBook
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Molecular Medicine and Biomedical Research in the Era of Precision Medicine: New technologies and personalized drug therapies for patient care provides researchers with an extensive overview of recent advances in molecular biology impacting the development of targeted therapies. It delivers insights into the pathobiological and pathogenetic mechanisms of various diseases, providing a detailed study of the latest personalized interventions to be implemented across such conditions.The book covers a range of technologies including RNA-sequencing, AI, Machine Learning, gene therapy, omics and nanotechnology, delving into their clinical applications across various diseases. It also tackles targeted treatments of different disease types including acute, chronic, infectious and noncommunicable diseases. Future perspectives are also covered.This book provides an in-depth study across molecular medicine, drug discovery and delivery, disease diagnosis and prevention, and therapeutic interventions, acting as an invaluable interdisciplinary reference for researchers across the biomedical sciences.

CRISPR-Cas-Based Genome Editing for Treating Human Diseases - Part B

  • 1st Edition
  • Volume 210
  • January 1, 2025
  • Vijai Singh
  • English
  • Hardback
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  • eBook
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CRISPR-Cas-based genome editing for treating human diseases part B represents CRISPR-Cas systems for genome editing. Currently, CRISPR-Cas systems are proven a key technology for targeted genome editing which is acting as a simple, rapid, and cost-effective solution. CRISPR-Cas9 system is being used in microbial genome editing, mammalian genome editing, disease models, and many. It has shown potential in human disease treatment. However, it is not easy to find CRISPR-Cas systems genome editing in a single source. This volume offers CRISPR-Cas systems for metabolic disorders, retinal disease cataract and blindness, muscular dystrophy, cardiac disease, diabetes, liver disease, lung disease, kidney diseases, rare disease, heredity disease, neurological disorders and CRISPR challenges in clinical developments. This volume highlights a number of aspects of the CRISPR-Cas sytems that can help the basic understanding of students, researchers, clinicians, entrepreneurs, and stakeholders to perform their research with great interest.

Kaufman’s Atlas of Mouse Development Supplement

  • 2nd Edition
  • January 1, 2025
  • Gillian Morriss-Kay + 1 more
  • English
  • Hardback
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  • eBook
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Kaufman's Atlas of Mouse Development Supplement, Second edition, continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems. This book explores the developmental origins of the organ systems, following the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development.In recent years there has been considerable progress in imaging techniques and molecular and experimental studies in the mouse, which in turn has strengthened the importance of the mouse as a model for understanding human development. In this new edition, each chapter has been updated to include the latest research in these areas, while three brand new chapters are also included, covering the functional aspects of mouse and human heart development, the immune system, and the inner ear. These additions ensure an up-to-date resource for all biomedical scientists who use the mouse as a model species for understanding the normal and abnormal development of human systems.

Nuclear Proteins

  • 1st Edition
  • Volume 143
  • January 1, 2025
  • Rossen Donev
  • English
  • Hardback
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  • eBook
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Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics.

Artificial Intelligence in Microbiology: Scope and Challenges volume-II

  • 1st Edition
  • Volume 56
  • January 1, 2025
  • Akanksha Srivastava + 1 more
  • English
  • Hardback
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  • eBook
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Nowadays, the field of microbiology is undergoing a revolutionary change due to the emergence of Artificial Intelligence (AI). AI is being used to analyze massive data in a predictable form, about the behavior of microorganisms, to solve microbial classification-related problems, exploring the interaction between microorganisms and the surrounding environment. It also helps to extract novel microbial metabolites which have been used in various fields like medical, food and agricultural industries. As the pace of innovation in Microbiology is accelerating, the use of AI in these industries will be beneficial. AI will not only show its extraordinary potential in expanding the market of antibiotics, food, and agriculture but also offer an eco-friendly, safer, and profitable solution to the respective industries. It would be challenging to search out specific features and discuss future research on AI in microbiology with a wide perspective.

Advances in Clinical Chemistry

  • 1st Edition
  • Volume 124
  • January 1, 2025
  • Gregory S. Makowski
  • English
  • Hardback
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  • eBook
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The ACC series provides the fundamentals of physiologic and pathophysiologic biochemistry in general and Clinical Chemistry specifically. Complex molecular pathways are elucidated using historical, current and emerging technologies such as biosensor design and development. Identification of novel biomarkers and accurate and precise analysis are key to cutting-edge patient care, diagnostics and treatment. The ACC series strategically focuses on new tools for the detection of novel biomarkers especially in light of an aging worldwide population faced with increased prevalence of chronic disease, many of which lack early diagnostic tools but are so essential to patient care and socioeconomic outcome.

Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

  • 7th Edition
  • December 2, 2024
  • Reed E. Pyeritz + 2 more
  • English
  • Hardback
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  • eBook
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Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics: Ophthalmologic, Hearing, Craniofacial, Dermatologic, Connective Tissue, and Skeletal Disorders, Seventh Edition bridges the gap between high-level molecular genetics and practical applications. With nearly 5,000 pages of detailed coverage and contributions from over 250 of the world’s most trusted authorities in medical genetics, this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies for this growing field.This comprehensive yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine more broadly. In this volume, leading international contributors examine the genetics of ophthalmologic, hearing, craniofacial, dermatologic, connective tissue, and skeletal disorders, with emphasis on understanding the genetic mechanisms underlying these disorders, diagnostic approaches, and treatment methods that make use of current genomic technologies and translational studies.

Genomics, Populations, and Society

  • 1st Edition
  • December 1, 2024
  • Ruth Chadwick + 1 more
  • English
  • Paperback
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  • eBook
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Genomics, Populations, and Society, a new volume in the Genomic and Precision Medicine in Clinical Practice series, considers the vast and thorny web of ELSI topics in genomics, from bioethics to healthcare applications, healthcare economics, genomic data management, and population dynamics. Emphasis is placed on the impact of rapid genomic advances on ethical, sociocultural and lifestyle dimensions. Healthcare and health economics topics include genomics and digital health, genome editing, and genomics and infectious disease management. Legal issues related to data ownership, equity, access, probity, consent, and confidentiality are also discussed in-depth, along with sociocultural topics such as community engagement, consanguinity, and more.Here, a range of readers from researchers to clinicians, policy administrators, lawyers, economists and social scientists will discover carefully crafted, synthesized discussions on ELSI topics in genomics to power new scientific advances and genomic medicine implementation.

Methods for Monitoring Mitochondrial Functions During Pathogen Infection

  • 1st Edition
  • Volume 190
  • December 1, 2024
  • Saverio Marchi + 1 more
  • English
  • Hardback
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  • eBook
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Methods for Monitoring Mitochondrial Functions During Pathogen Infection, Volume 188 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Mitochondrial Labeling with Fluorescent Proteins for Enhanced Morphological Characterization and Visualization of Intercellular Mitochondrial Transfer, Visualizing mitochondrial electron transport chain complexes and super-complexes during infection of human macrophages with Legionella pneumophila, Quantitative assessment of mitochondrial membrane potential in macrophages in sepsis, Quantification of mitochondrial reactive oxygen species in macrophages during sepsis, and much more.Additional chapters cover Quantification of intracellular and mitochondrial ATP content in macrophages during lipopolysaccharide-induced inflammatory response, Analysis of cytosolic mtDNA release during Staphylococcus Aureus infection, Monitoring mitochondria dynamics upon infection using a tomographic approach, A screening system to determine bacterial effects on MADCAM1 expression by high endothelial venule cells, Isolation of mitochondria from Mycobacteria infected cells, Monitoring mitochondrial localization of Mycobacterial proteins, and more.