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Books in Molecular and genetic toxicology

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    • Advances in Molecular Toxicology

      • 1st Edition
      • Volume 9
      • October 11, 2015
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 2 2 9 0
      • eBook
        9 7 8 0 1 2 8 0 2 4 3 0 0
      Advances in Molecular Toxicology features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment and produced by the human body manifest themselves as toxins. The book is not strictly limited to documenting these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field.

    • Oxidative Stress and Neurodegenerative Disorders

      • 1st Edition
      • March 22, 2007
      • G. Ali Qureshi + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 2 8 0 9 4
      • eBook
        9 7 8 0 0 8 0 4 8 9 4 9 0
      Oxidative stress is the result of an imbalance in pro-oxidant/antioxid... homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage in models on neurological disorders. This book presents detailed information on various neurodegenerative disorders and their connection with oxidative stress. This information will provide clinicians with directions to treat these disorders with appropriate therapy and is also of vital importance for the drug industries for the design of new drugs for treatment of degenerative disorders.

    • ABC Proteins

      • 1st Edition
      • January 7, 2003
      • I Barry Holland + 3 more
      • English
      • Hardback
        9 7 8 0 1 2 3 5 2 5 5 1 2
      • eBook
        9 7 8 0 0 8 0 4 8 1 8 7 6
      ABC Proteins is an in-depth, up-to-date analysis of all that is known about the subject to date. It discusses and compares evolution, biology and mechanism of action of all known ABC proteins, including the first structural studies as well as clinical implications. It will be useful to anyone trying to stay abreast of the latest findings. This book is sure to become a classic and will regularly be updated.

    • Advances in Cancer Research

      • 1st Edition
      • Volume 67
      • November 22, 1995
      • English
      • Paperback
        9 7 8 0 1 2 4 1 5 7 0 7 1
      • eBook
        9 7 8 0 0 8 0 5 6 2 4 9 0
      Advances in Cancer Research is a biannual publication that includes timely reviews on the most cutting-edge issues in cancer research. Topics covered in Volume 67 include a developmental model of progenitor cell oncogenesis based on a description of transcriptional control; pathways of chromosome alteration in human epithelial cancers, using colorectal, breast, lung, and endometrial cancers as examples; the genetics of murine lung tumors; the molecular pathogenesis of AIDS-related lymphomas; HLA class I antigens in human tumors, focusing on abnormal MHC expression detected in human tumors and the biological role these alterations may have in tumor development; a summary of the information obtained by the molecular characterization of EBV diversity and discussion of its relevance for viral epidemiology, transmission, and pathogenesis. There are two reviews discussing angiogenesis: the first focuses on the role of scatter factor and the second, the VEGF-FH receptor system. The "Foundations in Cancer Research" article by Alfred G. Knudson is a personal account of his career studying mutation and cancer.