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Elsevier

Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

  • Molecular Mechanisms of Cancer Resistance

    Emerging Technologies and Therapeutic Strategies
    • 1st Edition
    • Ahmet Acar
    • English
    Molecular Mechanisms of Cancer Resistance: Emerging Technologies and Therapeutic Strategies explores innovative tools and strategies designed to address the critical issue of drug resistance in cancer treatment. This comprehensive volume is tailored for researchers, clinicians, and students, offering insights into the latest advancements and methodologies in the field. The book covers essential topics such as molecular mechanisms of drug resistance, the tumor microenvironment, and emerging technologies like single-cell analysis and computational modeling. Each chapter features contributions from leading experts, providing a multi-dimensional perspective on both foundational concepts and cutting-edge research.By engaging with this book, the academic audience gains access to groundbreaking research and therapeutic strategies that enhance understanding and practice. The knowledge acquired will inspire collaboration and innovation, ultimately contributing to more effective and personalized cancer treatment approaches.

  • Principles of Antiviral Drug Development

    Rapid Discovery Technologies and Practical Applications
    • 1st Edition
    • Ailin Liu
    • English
    Principles of Antiviral Drug Development: Rapid Discovery Technologies and Practical Applications systematically integrates the major experimental techniques and virtual drug screening methods involved in the discovery of antiviral drugs, and provides a detailed discussion of their applications: among them, the combination of virtual drug screening technologies coupled with experimental methods offers strong potential for the rapid discovery of antiviral agents. The book also discusses activity-guided extraction, isolation, and activity evaluation of active components in order to reveal the material basis of antiviral activity and preliminary mechanisms of action. The book also discusses: drug repurposing of approved medicines; and an analysis of the discovery and mechanistic studies of a series of antiviral natural products which offer important information on the needs of future research, development, together with the clinical application of new antiviral drugs.

  • Analytical Pharmacology

    • 1st Edition
    • Su Zeng + 1 more
    • English
    Analytical Pharmacology covers a wide range of analytical methods, including PCR, flow cytometry, molecular imaging, and gene editing, in the context of mechanistic studies, target discovery, biomarker development, drug metabolism, and clinical evaluation. The comprehensive scope and emphasis on emerging technologies make it a valuable resource for researchers seeking to understand how analytical tools are applied to solve key scientific problems in pharmacology and toxicology. Pharmaceutical industry specialists, including quality control analysts, regulatory affairs specialists and pharmaceutical technicians, will find value in understanding how modern analytical techniques can enhance drug quality assessment and compliance with regulatory requirements. For all readers interested in practical applications there are detailed descriptions of analytical techniques and validation methods. Case studies are used throughout to enrich theory and practical application.The book offers research and academic readers detailed information on the emerging technologies of spatial transcriptomics and spatial omics, supporting their application in research studies and teaching

  • Encyclopedia of Pharmacy Practice and Clinical Pharmacy

    • 2nd Edition
    • Zaheer-Ud-Din Babar
    • English
    Encyclopedia of Pharmacy Practice and Clinical Pharmacy, Second Edition, Three-Volume Set is a comprehensive reflection of the transformative shifts in pharmaceutical policy, practice, and research. Covering a wide range of subjects, including clinical pharmacy, socio-administrative and behavioral pharmacy, and the critical field of pharmacovigilance, this new edition is hailed as the most comprehensive reference resource in the field. With a collection of over 210 chapters contributed by field experts, the book seamlessly bridges the gap between foundational principles and emerging trends, providing readers with a rich understanding of the multifaceted aspects of pharmacy practice and clinical pharmacy.Readers will find this an indispensable tool that allows practitioners, researchers, and students alike to easily navigate the ever-changing landscape of pharmacy in the 21st century.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 67
    • English
    Annual Reports in Medicinal Chemistry, Volume 67 presents authoritative and forward‑looking reviews that capture current advances in medicinal chemistry, with a strong emphasis on molecular conjugates, hybrid therapeutics, and precision drug design. Contributions from leading international researchers examine emerging strategies for antiviral, antifungal, and antimicrobial drug development, including small‑molecule conjugates, aptamer–RNA platforms, terpene‑derived hybrids, and intracellular targeting approaches.The volume highlights how chemical innovation is being leveraged to address drug resistance, emerging viral threats, and unmet clinical needs, while also reflecting broader methodological advances in conjugate design, carrier systems, and structure–activity relationships. As with previous volumes in the series, ARMC 67 serves as both a critical reference and a forward‑looking guide for medicinal chemists in academia and industry.

  • Pharmaceutical Hot Melt Extrusion

    From Materials Selection to Commercial Production
    • 1st Edition
    • Purnima D. Amin
    • English
    Pharmaceutical Hot Melt Extrusion: From Materials Selection to Commercial Production is an authoritative resource on the evolving landscape of HME technology. The book explores the core principles of formulation development, equipment design, process scaling, and regulatory considerations, providing essential knowledge for researchers and industry professionals. It emphasizes innovative, green manufacturing practices, solvent-free processes, and patient-centric delivery systems, making it a vital guide for advancing pharmaceutical and nutraceutical formulations. This reference enhances understanding of cutting-edge HME applications, supporting environmentally sustainable practices and innovative product development for both academia and industry.It equips formulation scientists, R&D professionals, and students with the knowledge to accelerate research, improve efficiency, and translate laboratory innovations into market-ready solutions.

  • Anti-Obesity Drug Development

    Physiology, Pharmacology and Drug Delivery
    • 1st Edition
    • Fadia Salah Youssef + 1 more
    • English
    Anti-Obesity Drug Development: Physiology, Pharmacology and Drug Delivery is a complete reference for pharmaceutical researchers in this key area of research and clinical development. The contents of the book are organized in four parts. The first provides an overview of the foundations and historical development of anti-obesity drugs, including extensive discussion of comorbidities and how they impact drug activity and efficacy. Part two is dedicated to the drug targets involved in the progression of obesity treatment. These include GLPRI and GIPR agonists, Incretin/Glucagon, RM-493 and Liraglutide, Pramlintide and metreleptin, Growth Hormone, FXR and GPR131, and the Gut Microbiota. Part three discusses the most common drugs available in the market and their pharmacological parameters. The final part of the book covers all natural products known to have scientific evidence on the treatment of obesity. Anti-Obesity Drug Development: Physiology, Pharmacology and Drug Delivery is the perfect reference for pharmacology researchers and those involved in new drug development both in academic and corporate environments. Research-physicians, endocrinologists, and nutritionists will also benefit from the comprehensive overview of treatments covered in this book.

  • Integrating Artificial Intelligence with Virtual Screening

    A New Era in Drug Discovery
    • 1st Edition
    • Vivek Asati + 1 more
    • English
    Integrating Artificial Intelligence with Virtual Screening: A New Era in Drug Discovery addresses the evolving landscape of drug discovery by combining traditional virtual screening with cutting-edge artificial intelligence technologies. This volume offers an interdisciplinary guide to AI-driven ligand and structure-based screening methods, including machine learning, deep learning, and generative models, thus enabling faster and more accurate identification of drug candidates. It covers mathematical models, computational workflows, and optimization strategies such as Pareto-based and physics-based approaches.Sections also discuss challenges in navigating ultra-large chemical libraries and present practical case studies that demonstrate real-world applications. Edited by leading researchers, the book provides authoritative insights suited for graduate students, researchers, and industry professionals. Users will be empowered by the latest tools and knowledge to innovate drug discovery pipelines and support the development of precision medicines and foster advancements in pharmaceutical sciences.

  • Medicines Safety and Pharmacovigilance

    Introduction, Concepts, and Applications
    • 1st Edition
    • Rabia Hussain
    • English
    Medicines Safety and Pharmacovigilance: Introduction, Concepts, and Applications provides a comprehensive guide for pharmaceutical professionals navigating the complex landscape of medicine safety and vigilance. Designed to support strategic decision-making, this reference draws on industry expertise to uphold the highest standards of patient care. The book addresses essential regulatory requirements, reporting obligations, and ethical considerations, offering practical guidance for implementing effective pharmacovigilance systems. Covering the latest technological advancements, it ensures readers are equipped to meet the modern challenges faced by healthcare and pharmaceutical sectors in monitoring the safety and efficacy of medicines for diverse populations worldwide.Beyond the foundational concepts, the book presents detailed insights into signal detection, risk management plans, and the real-world application of pharmacovigilance through case studies from both high- and low-middle-income countries. It examines the pivotal role of pharmacists and the importance of tailored approaches for special populations, while emphasizing effective communication of medicines safety.

  • Nonclinical Evaluation Studies of Cellular and Gene Therapy Products

    Strategies, Models, and Regulatory Frameworks
    • 1st Edition
    • Quanjun Wang + 2 more
    • English
    Nonclinical Evaluation Studies of Cellular and Gene Therapy Products: Strategies, Models, and Regulatory Frameworks systematically explores the nonclinical evaluation of Cell and Gene Therapies (CGT) products, emphasizing risk mitigation and innovation. The book provides comprehensive coverage, including 20+ chapters spanning preclinical toxicology, pharmacokinetics, and novel evaluation models. It is the first book to integrate organ-on-chip models into CGT evaluation, reflecting FDA/NMPA modernization initiatives. It includes practical guidance on addressing CRISPR off-target effects, immunogenicity, and long-term carcinogenicity risks.

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