Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

Books Journals

Fundamentals of Biologicals Regulation

2nd Edition
November 1, 2025
Rebecca Sheets + 6 more
English
Paperback
9 7 8 0 4 4 3 2 1 9 8 8 7
eBook
9 7 8 0 4 4 3 2 1 9 8 9 4

Fundamentals of Biologicals Regulation: Vaccines and Biotechnology Medicines, Second Edition serves as an introduction to the international regulatory arena in which biologicals are developed, offering an overview of processes and insights into the scientific concepts underpinning global regulations. The book provides in-depth coverage of Quality by Design, Combination Products, Quality Target Product Profiles, Risk Management Plans, REMS, and switching from reliance on in vivo to in vitro analytical methods. It reflects new developments and processes accelerated by the COVID-19 vaccine experience, including emergency use authorizations and conditional marking authorizations. New pedagogic elements and case studies have been added to improve learning outcomes.This book provides multiple levels of readership, with guidance on basic concepts, a detailed look at regulatory challenges, and practical insights into how regulators consider regulatory science and regulatory process issues across various regions, with an emphasis on the European Medicines Agency and the U.S. Food and Drug Administration.

Ketamine

1st Edition
November 1, 2025
Albert Dahan + 1 more
English
Paperback
9 7 8 0 4 4 3 2 9 9 3 0 8
eBook
9 7 8 0 4 4 3 2 9 9 3 1 5

Pharmacology of Ketamine: Fundamentals, Applications, Delivery Systems and Clinical Aspects explores the multifaceted properties of ketamine for diverse applications, delving into dosing strategies, routes of administration, and their pharmacological implications. The book begins with an introduction that underscores the need to bridge research and practice. It then delves into the pharmacological intricacies of ketamine, dissecting mechanisms and dosing strategies and exploring the diverse routes of administration and their impact on ketamine's metabolites.The book then explores the PK and PD characteristics of ketamine, followed by a deep dive into clinical applications emphasizing anesthesia, psychiatric therapy, and emerging treatments. The final part of the book covers addiction, toxicity, and future research perspectives. It will serve as a comprehensive reference tailored to the needs of both researchers and clinicians involved in the administration and study of ketamine.

Capsaicin, the Pungent Principle in Hot Pepper

1st Edition
November 1, 2025
Arpad Szallasi
English
Hardback
9 7 8 0 4 4 3 3 0 2 0 2 2
eBook
9 7 8 0 4 4 3 3 0 2 0 3 9

Capsaicin, the Pungent Principle in Hot Pepper: From Basic Pharmacology to Therapeutic Applications explores capsaicin's biological and pharmacological characteristics, from its discovery and isolation to its receptor identification and antagonists. The book's structure is divided into three sections, starting with the historical development of research on capsaicin. This foundational section provides a thorough understanding of the compound's journey from a simple pungent ingredient to a significant element in pharmacological studies. The second part of the book delves into capsaicin’s biological effects and pharmacology, covering areas such as nociception, pain, salivary secretion, body temperature regulation, and blood pressure regulation.Finally, the book examines the clinical applications of capsaicin, discussing potential future developments in desensitization, pain relief, injections, effects on the tumor microenvironment, appetite control, and longevity. This book is invaluable for pharmacology researchers and clinicians in pain management and cancer, offering insights into the unique characteristics and therapeutic potential of capsaicin.

Machine Learning in Drug Development: Part 2

1st Edition
Volume 65
November 1, 2025
Joy Feng + 1 more
English

Machine Learning in Drug Development: Part Two, Volume 65 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this volume explore Transforming Modern Drug Discovery with Machine Learning – Applications in Ligand-based Drug Design, Optimizing Multi-Modal Drug Design Through Computational Pocket Mapping and Data Integration, Harnessing AI for Nucleic Acid Drug Discovery: Small Molecule Targeting DNA and RNA, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, and more.Additional section delve into Artificial Intelligence in the Development of Antiviral Drugs – Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery

Progress in Medicinal Chemistry

1st Edition
Volume 64
October 30, 2025
Jonathan Bentley + 1 more
English

Progress in Medicinal Chemistry, Volume 64 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

The Science of Pharmacology

1st Edition
October 15, 2025
Jahangir Moini + 3 more
English

The Science of Pharmacology offers a detailed and contemporary exploration of medications, delving into the scientific principles behind drug actions and their therapeutic applications. It is an essential resource for students in pharmacology and pharmaceutical sciences, providing foundational knowledge on a wide range of topics. The book addresses the effects of drugs on various bodily systems, such as the nervous, respiratory, and cardiovascular systems, and also covers their impact on mental health and behavior. Beyond the core topics, the book also discusses special subjects like herbal medications and drug interactions.It includes valuable teaching materials, including test banks and quizzes, and offers comprehensive insights into toxicological treatments, making it an invaluable tool for both learning and teaching in the field.

Curcumin Bioavailability and Sustainability as Therapeutic Agent

1st Edition
October 1, 2025
Mahmood Ahmed + 1 more
English
Paperback
9 7 8 0 4 4 3 2 9 1 9 6 8
eBook
9 7 8 0 4 4 3 2 9 1 9 7 5

Curcumin Bioavailability and Sustainability as Therapeutic Agent: Strategies for Sustained Release Curcumin is a comprehensive reference on techniques to enhance the bioavailability of curcumin, while also covering sustainability aspects across its production cycle. This book focuses on the information needs of pharmaceutical scientists aiming at developing drug delivery systems and formulations that can maximize the therapeutic impact of curcumin drugs. After an introduction to curcumin therapeutic properties, the authors delve into the bioavailability challenges confronted by curcumin, discussing influencing factors, pharmacokinetic pathways, and formulations to augment its bioaccessibility. Chapter 3 explores innovative formulation paradigms, encompassing nanoparticle-based delivery systems and lipidic matrices, tailored to overcome solubility limitations and increase absorptive efficacy. Chapter 4 covers delivery systems, encompassing prodrug strategies, encapsulation modalities, and nanocarrier technologies. Chapter 5 investigates sustainable sourcing and production, raising awareness to ethical cultivation practices, eco-friendly extraction methodologies, and proficient waste management techniques within curcumin production processes. In Chapter 6 discusses balancing bioavailability augmentation with sustainability principles including case studies. Chapter 7 navigates the domain of pharmacokinetic studies and clinical trials, providing an overview of bioaccessibility and bioavailable formulations. Chapter 8 explores safety profiles, regulatory requirements, and quality benchmarks, encompassing product labeling and claims concerning curcumin's bioavailability and sustainability. Chapter 9 casts a future view contemplating nascent technologies for bioavailability and sustainability optimization. The final chapter concludes the book with the author's observations on its central themes. Curcumin Bioavailability and Sustainability as Therapeutic Agent: Strategies for Sustained Release Curcumin provides practical strategies to be explored by pharmaceutical scientists in increasing bioavailability of curcumin formulations. Research physicians and nutritionists may also benefit from the evidence-based information on curcumin's therapeutic activities provided across the book.

Drug Metabolism in Diseases

2nd Edition
October 1, 2025
Wen Xie
English

Drug Metabolism in Diseases: Leveraging Drug Metabolism and Disposition in Precision Medicine and Therapeutic Development, Second Edition provides essential knowledge for pharmaceutical scientists and biologists to understand the interplay between diseases and physiological conditions, impacting drug metabolism and its implications in personalized treatment. Expanded with six new chapters since the first edition, this updated book covers the latest scientific findings. Other important points include the book’s comprehensive reference on mutual effects between drug metabolism and diseases, implications in precision medicine, and therapeutic development. Pharmaceutical scientists, drug metabolism researchers, and research physicians will benefit from the expert insights provided.

Handbook of Melatonin-Based Therapy and its Applications

1st Edition
October 1, 2025
Alejandro Romero Martínez + 2 more
English
Paperback
9 7 8 0 4 4 3 3 0 2 4 0 4
eBook
9 7 8 0 4 4 3 3 0 2 4 1 1

Handbook of Melatonin-Based Therapy and its Applications provides pharmaceutical researchers and health professionals with a comprehensive reference on the applications of melatonin in the therapeutic setting. Succinct, meticulously organized, and expertly written, this book addresses all essential aspects. It starts with an overview of safe use of melatonin, translational aspects, and its prospection. The next section of the book covers a variety of clinical applications, including dosage, pharmacokinetics and pharmacodynamic profiles, toxicity, and principles of action. The chapters in this section cover applications to both adults and pediatric patients suffering from conditions like skin cancers, GI issues, psychiatric, hepatic and ocular conditions.This is a comprehensive resource for pharmaceutical scientists and health professionals involved in developing therapies and applying them to patients. Researchers in the fields of medicine, biology, neuroscience, and pharmacology conducting studies related to melatonin-based will benefit from insights into the latest research findings, clinical trials, and therapeutic approaches.

Theoretical and Clinical Geropharmacology

1st Edition
Volume 104
October 1, 2025
Mehmet Can Atayik + 1 more
English

Theoretical and Clinical Geropharmacology, explores the emerging field of senotherapeutics, which focuses on targeting cellular senescence to reduce age-related diseases and promote healthy aging. Chapters in this new release include Senotherapeutics: Milestones, innovations, and future prospects, Game Changer: Navigating between challenges and hopes in Geropharmacology, Next-Gen Senotherapeutics: AI/ML-driven strategies for aging and age-related disorders, Pharmacological frontiers in senescence: Transforming senescence with drug repurposing, Pharmacological potential of calorie restriction mimetics in mitigating brain aging, Isothiocyanates from cruciferous plants as geroprotectors, and much more.Other chapters cover Cellular parabiosis as a senotherapeutic approach, Molecular imaging for senescent cells-targeted therapeutics in aging and age-related diseases, Mitochondria-associa... membranes (MAMs) in age-related heart diseases, role of endoplasmic reticulum stress, Cellular senescence and senotherapeutics in cardiovascular diseases, Risk of senescence, polypharmacy, and their outcomes in elderly cardiovascular disease patients, Geropharmacology and gastrointestinal surgery, Oxygen-ozone adjunct therapy in aging and senescence-related disorders, and more.

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