Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

Books Journals

Curcumin Bioavailability and Sustainability as Therapeutic Agent

1st Edition
October 1, 2025
Mahmood Ahmed + 1 more
English
Paperback
9 7 8 0 4 4 3 2 9 1 9 6 8
eBook
9 7 8 0 4 4 3 2 9 1 9 7 5

Curcumin Bioavailability and Sustainability as Therapeutic Agent: Strategies for Sustained Release Curcumin is a comprehensive reference on techniques to enhance the bioavailability of curcumin, while also covering sustainability aspects across its production cycle. This book focuses on the information needs of pharmaceutical scientists aiming at developing drug delivery systems and formulations that can maximize the therapeutic impact of curcumin drugs. After an introduction to curcumin therapeutic properties, the authors delve into the bioavailability challenges confronted by curcumin, discussing influencing factors, pharmacokinetic pathways, and formulations to augment its bioaccessibility. Chapter 3 explores innovative formulation paradigms, encompassing nanoparticle-based delivery systems and lipidic matrices, tailored to overcome solubility limitations and increase absorptive efficacy. Chapter 4 covers delivery systems, encompassing prodrug strategies, encapsulation modalities, and nanocarrier technologies. Chapter 5 investigates sustainable sourcing and production, raising awareness to ethical cultivation practices, eco-friendly extraction methodologies, and proficient waste management techniques within curcumin production processes. In Chapter 6 discusses balancing bioavailability augmentation with sustainability principles including case studies. Chapter 7 navigates the domain of pharmacokinetic studies and clinical trials, providing an overview of bioaccessibility and bioavailable formulations. Chapter 8 explores safety profiles, regulatory requirements, and quality benchmarks, encompassing product labeling and claims concerning curcumin's bioavailability and sustainability. Chapter 9 casts a future view contemplating nascent technologies for bioavailability and sustainability optimization. The final chapter concludes the book with the author's observations on its central themes. Curcumin Bioavailability and Sustainability as Therapeutic Agent: Strategies for Sustained Release Curcumin provides practical strategies to be explored by pharmaceutical scientists in increasing bioavailability of curcumin formulations. Research physicians and nutritionists may also benefit from the evidence-based information on curcumin's therapeutic activities provided across the book.

Drug Metabolism in Diseases

2nd Edition
October 1, 2025
Wen Xie
English

Drug Metabolism in Diseases: Leveraging Drug Metabolism and Disposition in Precision Medicine and Therapeutic Development, now in second edition, provides pharmaceutical scientists and biologists with the needed foundational knowledge required to understand the interplay between diseases and physiological conditions, how they impact drug metabolism and disposition, and its implications in personalized treatment. The book has been expanded with six new chapters, and completely updated with the scientific findings since the first edition published in 2016. The new chapters in the book cover drug metabolism in metabolic syndrome , transplant patients, geriatric patients, the developmental regulation of drug metabolism and disposition, the effect of gut microbiota on xenobiotic and endobiotic metabolism, the regulation of expression of drug-metabolizing enzymes by oncogenic signaling pathways, and drug metabolism in HIV patients. All other chapters in the first edition like drug metabolism in pregnancy, pediatric patients, patients of cardiovascular disease, and kidney diseases were completely updated to include the latest research results and references. Drug Metabolism in Diseases: Leveraging Drug Metabolism and Disposition in Precision Medicine and Therapeutic Development is a comprehensive reference on the mutual effect between drug metabolism and diseases, which has great implications in precision medicine and therapeutic development. Pharmaceutical scientists and drug metabolism researchers in academia and corporate R&D departments will benefit from the expanded coverage provided by expert authors. Research physicians interested in better understand the impact of diseases in drug metabolism will also benefit from the comprehensive overview of the area.

Handbook of Melatonin-Based Therapy and its Applications

1st Edition
October 1, 2025
Alejandro Romero Martínez + 2 more
English
Paperback
9 7 8 0 4 4 3 3 0 2 4 0 4
eBook
9 7 8 0 4 4 3 3 0 2 4 1 1

Handbook of Melatonin-Based Therapy and its Applications provides pharmaceutical researchers and health professionals with a comprehensive reference on the applications of melatonin in the therapeutic setting. Succinct, meticulously organized, and expertly written, this book addresses all essential aspects. It starts with an overview of safe use of melatonin, translational aspects, and its prospection. The next section of the book covers a variety of clinical applications, including dosage, pharmacokinetics and pharmacodynamic profiles, toxicity, and principles of action. The chapters in this section cover applications to both adults and pediatric patients suffering from conditions like skin cancers, GI issues, psychiatric, hepatic and ocular conditions.This is a comprehensive resource for pharmaceutical scientists and health professionals involved in developing therapies and applying them to patients. Researchers in the fields of medicine, biology, neuroscience, and pharmacology conducting studies related to melatonin-based will benefit from insights into the latest research findings, clinical trials, and therapeutic approaches.

Theoretical and Clinical Geropharmacology

1st Edition
Volume 104
October 1, 2025
Mehmet Can Atayik + 1 more
English

This book explores the emerging field of senotherapeutics, which focuses on targeting cellular senescence to reduce age-related diseases and promote healthy aging. As the population ages, there is growing interest in developing senotherapeutic strategies to delay or reverse age-related degenerative processes. Senotherapeutics offers promising approaches to achieve this goal by addressing the key factors that drive cellular aging. Fundamental mechanisms of cellular senescence, the potential of senolytic and senomorphic compounds in integrating senescence-associated pathways, and their relevance in conventional geropharmacology are offered to the readers. The current volume also highlights recent advances, challenges, and future directions, emphasizing developing senotherapeutic medications to promote longevity and improve healthspan.

Machine Learning in Drug Development: Part 1

1st Edition
Volume 64
October 1, 2025
Joy Feng + 1 more
English

Machine Learning in Drug Development: Part 1, Volume 63 in this series Annual Reports on Medicinal Chemistry, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

Comprehensive Toxicology

4th Edition
September 1, 2025
Charlene McQueen
English
Hardback
9 7 8 0 3 2 3 9 5 4 8 8 4
eBook
9 7 8 0 3 2 3 9 5 4 8 9 1

Comprehensive Toxicology, Fourth Edition, Fifteen Volume Set continues the legacy that began with the first edition in 1997, serving as an indispensable reference for toxicology researchers. This edition focuses on understanding the mechanisms by which chemicals affect biological systems and cause adverse health effects. Edited by a distinguished editorial board and featuring 400 in-depth contributions from experts around the globe, this comprehensive work spans fifteen volumes and nearly 9,000 pages, covering all major organ systems and general principles of toxicology. This extensively revised edition includes around 30 new chapters on modern testing strategies and novel in vitro models, such as organ-on-a-chip systems.It also explores computational approaches, new risk and safety assessment methods, harmonization, artificial intelligence, and the microbiome. As the most authoritative resource in toxicology, it continues to support researchers, faculty, and students in toxicology, as well as professionals in medical, veterinary, food, environmental, chemical, and pharmaceutical industries and international regulatory agencies.

Fundamentals of Biologicals Regulation

2nd Edition
September 1, 2025
Rebecca Sheets + 6 more
English
Paperback
9 7 8 0 4 4 3 2 1 9 8 8 7
eBook
9 7 8 0 4 4 3 2 1 9 8 9 4

Fundamentals of Biologicals Regulation: Vaccines and Biotechnology Medicines, Second Edition serves as an introduction to the international regulatory arena in which biologicals are developed, offering an overview of processes and insights into the scientific concepts underpinning global regulations. The book provides in-depth coverage of Quality by Design, Combination Products, Quality Target Product Profiles, Risk Management Plans, REMS, and switching from reliance on in vivo to in vitro analytical methods. It reflects new developments and processes accelerated by the COVID-19 vaccine experience, including emergency use authorizations and conditional marking authorizations. New pedagogic elements and case studies have been added to improve learning outcomes.This book provides multiple levels of readership, with guidance on basic concepts, a detailed look at regulatory challenges, and practical insights into how regulators consider regulatory science and regulatory process issues across various regions, with an emphasis on the European Medicines Agency and the U.S. Food and Drug Administration.

Pharmacological Targets in Metabolic Diseases

1st Edition
September 1, 2025
Marcos Roberto de Oliveira
English
Paperback
9 7 8 0 4 4 3 2 7 3 7 0 4
eBook
9 7 8 0 4 4 3 2 7 3 7 1 1

Pharmacological Targets in Metabolic Diseases: Challenges and Opportunities serves as an in-depth guide to potential drug development targets for therapeutic advancements. It addresses both signaling pathways and specific proteins, presenting strategies to modulate the molecular and cellular changes observed in metabolic diseases through the use of new or classical drugs. This comprehensive text begins with an overview of metabolic diseases, detailing biological changes and identifying pharmacological targets at molecular, subcellular, and cellular levels, laying the foundation for targeted therapeutic interventions. The book further delves into the pharmaceutical targeting of organs, including a dedicated chapter on the gut-brain axis.It reviews advances in metabolic syndrome research, explores inborn errors of metabolism, and examines the pharmacological potential of natural molecules. A section is devoted to the role of the microbiota in metabolic disease therapeutics, followed by discussions on the impact of aging, nanotechnology, the environment, and diagnostic techniques. This resource is essential for researchers, physicians, nutritionists, and biologists seeking detailed information on therapeutic targets for treating metabolic conditions.

Capsaicin, the Pungent Principle in Hot Pepper

1st Edition
September 1, 2025
Arpad Szallasi
English
Hardback
9 7 8 0 4 4 3 3 0 2 0 2 2
eBook
9 7 8 0 4 4 3 3 0 2 0 3 9

Capsaicin, the Pungent Principle in Hot Pepper: From Basic Pharmacology to Therapeutic Applications explores capsaicin's biological and pharmacological characteristics, from its discovery and isolation to its receptor identification and antagonists. The book's structure is divided into three sections, starting with the historical development of research on capsaicin. This foundational section provides a thorough understanding of the compound's journey from a simple pungent ingredient to a significant element in pharmacological studies. The second part of the book delves into capsaicin’s biological effects and pharmacology, covering areas such as nociception, pain, salivary secretion, body temperature regulation, and blood pressure regulation.Finally, the book examines the clinical applications of capsaicin, discussing potential future developments in desensitization, pain relief, injections, effects on the tumor microenvironment, appetite control, and longevity. This book is invaluable for pharmacology researchers and clinicians in pain management and cancer, offering insights into the unique characteristics and therapeutic potential of capsaicin.

Handbook of Intervention Science

1st Edition
July 1, 2025
Laura N.Gitlin + 1 more
English
Paperback
9 7 8 0 4 4 3 2 1 6 6 4 0
eBook
9 7 8 0 4 4 3 2 1 6 6 5 7

Handbook of Intervention Science: From Design to Implementation discusses multiple approaches for developing and advancing interventions at the individual, family, community, health system, and policy level. The book focuses on creating interventions suitable for diverse populations from racial, ethnical, geographical, and socioeconomical perspectives. Combining best practices with a practical approach, the book enables readers to advance their intervention research. It covers intervention design, data capture in trials, and evaluation. Decision trees help illustrate when to move forward with an implementation relative to the need for further work.

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