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Elsevier

Books in Pharmacology general

Providing foundational knowledge, this collection covers drug mechanisms, receptor pharmacology, and therapeutic principles. Supporting students, educators, and researchers, it features core concepts, emerging trends, and interdisciplinary approaches that underpin pharmaceutical science and clinical practice.

  • Quercetin in Drug Discovery

    • 1st Edition
    • Gautam Sethi + 2 more
    • English
    Quercetin in Drug Discovery is a detailed reference exploring the multifaceted pharmacological potential of quercetin, a naturally occurring flavonoid with significant therapeutic promise. Addressing the critical need for consolidated knowledge, this guide highlights quercetin’s diverse biological activities and the translational challenges limiting its clinical applications, making it essential for researchers and pharmaceutical scientists. The comprehensive table of contents covers quercetin’s pharmacological properties, molecular docking studies, and ADME profiles, alongside therapeutic applications in cardiovascular diseases, cancer, and other conditions. It further examines bioavailability enhancement strategies, drug formulation, innovative delivery systems, and clinical trial evidence. Contributions from leading experts provide detailed insights into signaling pathways, molecular targets, and synthetic derivatives. Quercetin in Drug Discovery equips pharmacologists, medicinal chemists, and pharmaceutical scientists with critical information to advance research and drug development. By addressing bioavailability issues and regulatory considerations, this reference supports the translation of quercetin from bench to bedside, fostering innovation in natural product-based therapeutics.

  • Current State of Alzheimer's and Parkinson's Disease Research and its Pharmacology

    • 1st Edition
    • Volume 108
    • English
    Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Integrating Artificial Intelligence with Virtual Screening

    A New Era in Drug Discovery
    • 1st Edition
    • Vivek Asati + 1 more
    • English
    Integrating Artificial Intelligence with Virtual Screening: A New Era in Drug Discovery addresses the evolving landscape of drug discovery by combining traditional virtual screening with cutting-edge artificial intelligence technologies. This volume offers an interdisciplinary guide to AI-driven ligand and structure-based screening methods, including machine learning, deep learning, and generative models, thus enabling faster and more accurate identification of drug candidates. It covers mathematical models, computational workflows, and optimization strategies such as Pareto-based and physics-based approaches.Sections also discuss challenges in navigating ultra-large chemical libraries and present practical case studies that demonstrate real-world applications. Edited by leading researchers, the book provides authoritative insights suited for graduate students, researchers, and industry professionals. Users will be empowered by the latest tools and knowledge to innovate drug discovery pipelines and support the development of precision medicines and foster advancements in pharmaceutical sciences.

  • The Pharmacology of Obesity

    • 1st Edition
    • Volume 107
    • English
    The Pharmacology of Obesity, Volume 107 in the Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Obesity Therapeutic Landscape, Challenges, and Unmet Needs, Diagnosis and Evaluation of Obesity for Therapeutic Selection, When to use First-Generation Anti-Obesity Medications?, GLP-1 Receptor Agonists in our Clinics, Future Directions in Obesity Pharmacotherapy: Novel Targets and Pipeline Therapies, Destigmatizing Obesity: from language to the clinical environment, and much more.Additional chapters cover Role of Nutrition and physical Activity in the Therapy of Obesity, Behavioral and Lifestyle Strategies in Obesity Management and Post-Bariatric Follow-Up, The interpretation of Body-composition Metrics in Obesity, Digital Health, Technology, Artificial Intelligence, and Wearables in Obesity Care, Metabolic Aging and Obesity: how Physiology Changes with Age, Endoscopic Bariatric and Metabolic Therapies, and What Patients Could Benefit from Bariatric Surgery?

  • Annual Reports in Medicinal Chemistry - Part 1

    • 1st Edition
    • Volume 67
    • English
    Annual Reports in Medicinal Chemistry, Volume 67 presents authoritative and forward‑looking reviews that capture current advances in medicinal chemistry, with a strong emphasis on molecular conjugates, hybrid therapeutics, and precision drug design. Contributions from leading international researchers examine emerging strategies for antiviral, antifungal, and antimicrobial drug development, including small‑molecule conjugates, aptamer–RNA platforms, terpene‑derived hybrids, and intracellular targeting approaches.The volume highlights how chemical innovation is being leveraged to address drug resistance, emerging viral threats, and unmet clinical needs, while also reflecting broader methodological advances in conjugate design, carrier systems, and structure–activity relationships. As with previous volumes in the series, ARMC 67 serves as both a critical reference and a forward‑looking guide for medicinal chemists in academia and industry.

  • Encyclopedia of Pharmacy Practice and Clinical Pharmacy

    • 2nd Edition
    • Zaheer-Ud-Din Babar
    • English
    Encyclopedia of Pharmacy Practice and Clinical Pharmacy, Second Edition, Four-Volume Set examines the science, practice, policy, and impact of medicines use across healthcare systems. Featuring approximately 204 chapters by international experts, it provides authoritative coverage of clinical pharmacy, pharmacy practice research, medication safety, medicines optimisation, pharmacoepidemiology... pharmacovigilance, health policy, social and administrative pharmacy, pharmacoeconomics, public health, digital health, implementation science, pharmacy education, and workforce development.Designed to support teaching, learning, and research, the encyclopedia integrates foundational concepts, research methods, professional practice, and emerging developments in healthcare delivery. Content is evidence-based and informed by current published research.The work serves undergraduate and postgraduate students, researchers, educators, pharmacists, clinicians, healthcare leaders, and policymakers, and supports programmes in pharmacy, pharmacology, public health, health services research, and healthcare management.Bringing together scientific evidence, professional practice, and policy perspectives, this updated edition offers a comprehensive reference for understanding the evolving role of medicines and pharmacy in improving patient and population health.

  • Anti-Obesity Drug Development

    Physiology, Pharmacology and Drug Delivery
    • 1st Edition
    • Fadia Salah Youssef + 1 more
    • English
    Anti-Obesity Drug Development: Physiology, Pharmacology and Drug Delivery is a complete reference for pharmaceutical researchers in this key area of research and clinical development. The contents of the book are organized in four parts. The first provides an overview of the foundations and historical development of anti-obesity drugs, including extensive discussion of comorbidities and how they impact drug activity and efficacy. Part two is dedicated to the drug targets involved in the progression of obesity treatment. These include GLPRI and GIPR agonists, Incretin/Glucagon, RM-493 and Liraglutide, Pramlintide and metreleptin, Growth Hormone, FXR and GPR131, and the Gut Microbiota. Part three discusses the most common drugs available in the market and their pharmacological parameters. The final part of the book covers all natural products known to have scientific evidence on the treatment of obesity.Anti-Obesity Drug Development: Physiology, Pharmacology and Drug Delivery is the perfect reference for pharmacology researchers and those involved in new drug development both in academic and corporate environments. Research-physicians, endocrinologists, and nutritionists will also benefit from the comprehensive overview of treatments covered in this book.

  • Pharmaceutical Hot Melt Extrusion

    From Materials Selection to Commercial Production
    • 1st Edition
    • Purnima D. Amin
    • English
    The Practical/User Manual for Making Pharmaceutical Products with Hot Melt Extrusion (HME) is a comprehensive resource addressing the evolving landscape of HME technology. This reference explores the core principles of formulation development, equipment design, process scaling, and regulatory considerations, providing essential knowledge for researchers and industry professionals. It emphasizes innovative, green manufacturing practices, solvent-free processes, and patient-centric delivery systems, making it a vital guide for advancing pharmaceutical and nutraceutical formulations.This reference enhances understanding of cutting-edge HME applications, supporting environmentally sustainable practices and innovative product development for both academia and industry. It equips formulation scientists, R&D professionals, and students with the knowledge to accelerate research, improve efficiency, and translate laboratory innovations into market-ready solutions.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 65
    • English
    Progress in Medicinal Chemistry, Volume 65 brings together state-of-the-art reviews and critical insights from leading scientists in the field. Each volume surveys the latest advances in drug discovery and development, with a focus on practical strategies, novel modalities, and real-world case studies. From target identification and structure-based design to optimization of pharmacokinetic properties, safety assessment, and translational science, these volumes provide a comprehensive, up-to-date overview for researchers, graduate students, and professionals working in medicinal chemistry, pharmacology, and related life sciences.Chapters in this new release cover Molecular Glues and Tactics in Hit Finding through to Lead Generation in Drug Discovery – current position and future directions.

  • Analytical Pharmacology

    • 1st Edition
    • Su Zeng + 1 more
    • English
    Analytical Pharmacology covers a wide range of analytical methods, including PCR, flow cytometry, molecular imaging, and gene editing, in the context of mechanistic studies, target discovery, biomarker development, drug metabolism, and clinical evaluation. The comprehensive scope and emphasis on emerging technologies make it a valuable resource for researchers seeking to understand how analytical tools are applied to solve key scientific problems in pharmacology and toxicology. Pharmaceutical industry specialists, including quality control analysts, regulatory affairs specialists and pharmaceutical technicians, will find value in understanding how modern analytical techniques can enhance drug quality assessment and compliance with regulatory requirements. For all readers interested in practical applications there are detailed descriptions of analytical techniques and validation methods. Case studies are used throughout to enrich theory and practical application.The book offers research and academic readers detailed information on the emerging technologies of spatial transcriptomics and spatial omics, supporting their application in research studies and teaching

  • Principles of Antiviral Drug Development

    Rapid Discovery Technologies and Practical Applications
    • 1st Edition
    • Ailin Liu
    • English
    Principles of Antiviral Drug Development: Rapid Discovery Technologies and Practical Applications systematically integrates the major experimental techniques and virtual drug screening methods involved in the discovery of antiviral drugs, and provides a detailed discussion of their applications: among them, the combination of virtual drug screening technologies coupled with experimental methods offers strong potential for the rapid discovery of antiviral agents. The book also discusses activity-guided extraction, isolation, and activity evaluation of active components in order to reveal the material basis of antiviral activity and preliminary mechanisms of action. The book also discusses: drug repurposing of approved medicines; and an analysis of the discovery and mechanistic studies of a series of antiviral natural products which offer important information on the needs of future research, development, together with the clinical application of new antiviral drugs.

  • The Science of Pharmacology

    • 1st Edition
    • Jahangir Moini + 3 more
    • English
    The Science of Pharmacology offers a detailed and contemporary exploration of medications, delving into the scientific principles behind drug actions and their therapeutic applications. It is an essential resource for students in pharmacology and pharmaceutical sciences, providing foundational knowledge on a wide range of topics. The book addresses the effects of drugs on various bodily systems, such as the nervous, respiratory, and cardiovascular systems, and also covers their impact on mental health and behavior. Beyond the core topics, the book also discusses special subjects like herbal medications and drug interactions.It includes valuable teaching materials, including test banks and quizzes, and offers comprehensive insights into toxicological treatments, making it an invaluable tool for both learning and teaching in the field.

  • Pharmacology of T-Cell Therapies

    • 1st Edition
    • Volume 106
    • English
    Pharmacology of T-Cell Therapies, Volume 106 in the Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics in this new release include Enhancing persistence of therapeutic T cells, T cell manufacturing impacts on in vivo function, Transient T cell therapies, In vivo T cell therapies, T cell subsets for therapy, Engineering T cell metabolism to enhance therapeutic efficacy, and Tracking Therapeutic T cells In Vivo contacts.

  • Pharma-Skript

    • 1st Edition
    • Michael Uhrig
    • German
    Pharmakologie kompakt. Klinisch gedacht. Nachhaltig gelernt.Pharmakologi... und Toxikologie sind komplex – müssen aber nicht kompliziert sein. Das Pharma-Skript bietet dir einen strukturierten Einstieg ins Fach und hilft dir, Arzneimittel wirklich zu verstehen: über 280 Wirkstoffe – von Aspirin bis Zolpidem – praxisnah erklärt und konsequent aufs Wesentliche fokussiert.Du lernst, Wirkmechanismen, Nebenwirkungen und Kontraindikationen systematisch herzuleiten – eine Fähigkeit, die sich in Prüfungen ebenso auszahlt wie im klinischen Alltag.Dabei unterstützen dich:einheitlich aufgebaute Kapitel für schnelle Orientierungüber 100 einprägsame Abbildungen zu zentralen Wirkmechanismenrund 275 kompakte Wirkstofftabellen mit allen prüfungsrelevanten Informationenklinisc... Fallbeispiele, die das pharmakologische Denken fördernein eigenes Kapitel zur Toxikologie mit typischen Toxidromen und TherapieansätzenDas Pharma-Skript ist ein zuverlässiger Begleiter für Studierende der Human- und Zahnmedizin, Physician Assistants, sowie für Auszubildende in medizinischen Berufen.Für alle, die Arzneimittel nicht nur lernen, sondern verstehen wollen.

  • Lo esencial en farmacología. Cursos Crash

    • 6th Edition
    • Spanish
    Con una formula que ha demostrado su exito a lo largo de los ultimos 25 a?os, cada volumen de la serie se ha actualizado por completo para facilitar el estudio. La serie esta escrita por estudiantes de ultimos cursos y recien graduados que acaban de superar sus examenes, y toda la informacion ha sido cuidadosamente revisada por profesores universitarios. Este volumen de la serie se ha mejorado para satisfacer las necesidades de los estudiantes de Medicina actuales, y las de los estudiantes y profesionales de otras disciplinas sanitarias que requieran un acceso rapido a los aspectos esenciales de la farmacologia. Cada capitulo guia de forma sucinta por todos los temas curriculares, integrando los aspectos clinicos con la ciencia basica relevante y evitando los detalles innecesarios o confusos. Los cuadros destacados a lo largo del texto ofrecen los apuntes, las sugerencias y los puntos clave esenciales. Se incluye una seccion de autoevaluacion totalmente revisada y adaptada a los ultimos formatos de examenes para comprobar los conocimientos y para ayudar en la preparacion de las pruebas. Completamente revisada y actualizada, esta sexta edicion ofrece un recurso accesible de aprendizaje y repaso que facilite la compresion de los principios y las aplicaciones de la farmacologia en todas las areas de la medicina y la cirugia. Comienza con un capitulo introductorio sobre los principios basicos de la farmacologia. En el resto de los capitulos, se describen los efectos de los farmacos en los distintos sistemas organicos y se incluyen actualizaciones sobre los avances farmacologicos mas recientes en medicina (p. ej., las nuevas terapias dirigidas en oncologia y enfermedades inflamatorias, asi como los nuevos tratamientos utilizados en el manejo de la diabetes y la insuficiencia cardiaca). La seccion de autoevaluacion se ha actualizado para reflejar el contenido y el estilo de varios examenes de pre- y posgrado. Las preguntas de autoevaluacion se centran en la farmacologia clinica y su aplicacion a casos reales de la practica clinica.

  • Machine Learning in Drug Development: Part 2

    • 1st Edition
    • Volume 65
    • English
    Machine Learning in Drug Development: Part Two, Volume 65 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this volume explore Transforming Modern Drug Discovery with Machine Learning – Applications in Ligand-based Drug Design, Optimizing Multi-Modal Drug Design Through Computational Pocket Mapping and Data Integration, Harnessing AI for Nucleic Acid Drug Discovery: Small Molecule Targeting DNA and RNA, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, and more.Additional section delve into Artificial Intelligence in the Development of Antiviral Drugs – Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 64
    • English
    Progress in Medicinal Chemistry, Volume 64 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Machine Learning in Drug Development: Part 1

    • 1st Edition
    • Volume 64
    • English
    Machine Learning in Drug Development: Part One, Volume 64 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field. Chapters in this release include Artificial Intelligence in Small Molecule and Nucleic Acid Research: A Review, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, AI-aided Drug Development for Protein Degraders: Biology Validation, Disease-association, Drug Repurposing, Transforming Modern Drug Discovery with Machine Learning, Artificial Intelligence in the Development of Antiviral Drugs: Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery.

  • Massachusetts General Hospital. Psicofarmacología y Neuroterapéutica

    • 2nd Edition
    • Theodore A. Stern + 2 more
    • Spanish
    Información práctica y específica de uno de los principales hospitales y departamentos de psiquiatría del mundo. La segunda edición de Massachusetts General Hospital. Psicofarmacología y Neuroterapéutica es la guía ideal sobre los más actuales tratamientos psicofarmacológicos y somáticos para enfermedades psiquiátricas y neurológicas. Compuesta por capítulos extraídos principalmente de la tercera edición de Massachusetts General Hospital. Tratado de Psiquiatría Clínica, de Stern et al., la presente obra, exhaustivamente revisada, se centra en los tratamientos psicotrópicos actuales, la terapia electroconvulsiva y la neuroterapéutica, lo que la convierte en una herramienta de ágil consulta, ideal para psiquiatras, psicólogos, internistas y enfermeras.

  • Comprehensive Toxicology

    • 4th Edition
    • Charlene McQueen
    • English
    Comprehensive Toxicology, Fourth Edition, Fifteen Volume Set continues the legacy that began with the first edition in 1997, serving as an indispensable reference for toxicology researchers. This edition focuses on understanding the mechanisms by which chemicals affect biological systems and cause adverse health effects. Edited by a distinguished editorial board and featuring 400 in-depth contributions from experts around the globe, this comprehensive work spans fifteen volumes and nearly 9,000 pages, covering all major organ systems and general principles of toxicology. This extensively revised edition includes around 30 new chapters on modern testing strategies and novel in vitro models, such as organ-on-a-chip systems.It also explores computational approaches, new risk and safety assessment methods, harmonization, artificial intelligence, and the microbiome. As the most authoritative resource in toxicology, it continues to support researchers, faculty, and students in toxicology, as well as professionals in medical, veterinary, food, environmental, chemical, and pharmaceutical industries and international regulatory agencies.

  • ​Theoretical and Clinical Geropharmacology​

    • 1st Edition
    • Volume 104
    • English
    ​Theoretical and Clinical Geropharmacology​, explores the emerging field of senotherapeutics, which focuses on targeting cellular senescence to reduce age-related diseases and promote healthy aging. Chapters in this new release include Senotherapeutics: Milestones, innovations, and future prospects, Game Changer: Navigating between challenges and hopes in Geropharmacology, Next-Gen Senotherapeutics: AI/ML-driven strategies for aging and age-related disorders, Pharmacological frontiers in senescence: Transforming senescence with drug repurposing, Pharmacological potential of calorie restriction mimetics in mitigating brain aging, Isothiocyanates from cruciferous plants as geroprotectors, and much more.Other chapters cover Cellular parabiosis as a senotherapeutic approach, Molecular imaging for senescent cells-targeted therapeutics in aging and age-related diseases, Mitochondria-associa... membranes (MAMs) in age-related heart diseases, role of endoplasmic reticulum stress, Cellular senescence and senotherapeutics in cardiovascular diseases, Risk of senescence, polypharmacy, and their outcomes in elderly cardiovascular disease patients, Geropharmacology and gastrointestinal surgery, Oxygen-ozone adjunct therapy in aging and senescence-related disorders, and more.

  • Farmacología humana

    • 7th Edition
    • Jesús Flórez Beledo + 2 more
    • Spanish
    La séptima edición de "Farmacología humana", obra de referencia de la especialidad en habla hispana, ofrece un texto exhaustivo y plenamente actualizado, guiado por la claridad expositiva y combinando el conocimiento teórico con la práctica clínica. Se han mantenido y reforzado los capítulos que abordan los principios básicos de la ciencia farmacológica y se han reflejado todas las novedades acontecidas desde la última edición y se ha incluido un nuevo capítulo dedicado a las "Terapias antoneoplásicas dirigidas". Otra novedad a destacar es la incorporación de nuevos colaboradores que junto con los ya tradicionales aúnan experiencia y frescura a esta magnífica obra.

  • Targeting Enzymes in the Brain

    • 1st Edition
    • Volume 102
    • English
    Targeting Enzymes in the Brain series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Pharmacovigilance

    A Practical Approach
    • 2nd Edition
    • Thao Doan + 4 more
    • English
    **Selected for 2026 Doody's Core Titles in Pharmacy**Written by multidisciplinary experts in the fields of pharmaceutical and patient safety, Pharmacovigilance: A Practical Approach, Second Edition, provides a succinct, easy-to-digest overview of an increasingly critical area of medical safety. From cover to cover, this concise resource offers essential information for physicians and other health care professionals, clinical researchers, and regulators who need a comprehensive, up-to-date source of information on the principles and practice of pharmacovigilance.

  • Emerging Therapeutic Targets and Drug Delivery Approaches in IBD

    • 1st Edition
    • Volume 101
    • English
    Emerging Therapeutic Targets and Drug Delivery Approaches in IBD, Volume 101 in this ongoing series, highlights new advances, with this volume presenting interesting chapters on timely topics, including Fibrosis in IBD – AXL as a Promising Therapeutic Target, Developing a pathway to test anti-fibrotic drugs in Crohn’s disease, Emerging therapeutics for the management of intestinal fibrosis and strictures, GCPII for IBD, Fistulas/stem cell products for IBD/Crohn’s, The landscape of new therapeutic opportunities for IBD, TL1A : A Model For The Use Of Precision Medicine For The Treatment of Crohn’s Disease and Ulcerative Colitis, Dectin-1 as a therapeutic target for IBD, and more.Additional sections cover BRD4 as an Emerging Epigenetic Therapeutic Target for Inflammatory Bowel Diseases, Scripps - S1P, The potential of targeting TREM-1 in Inflammatory Bowel Disease, and Microbiome therapies.

  • Traditional Medicines and Natural Products as Preventive and Therapeutic Agents Against COVID-19

    A Promising Response to the Global Unprecedented Pandemic
    • 1st Edition
    • Nabeelah Bibi Sadeer + 1 more
    • English
    Traditional Medicines and Natural Products as Preventive and Therapeutic Agents Against COVID-19: A Promising Response to the Global Unprecedented Pandemic presents comprehensive coverage of the pharmacological effects of natural products on the prevention and treatment of COVID-19. Sections provide traditional medicine approaches and their potential to prevent and treat COVID-19 infection, including traditional Chinese, Ayurvedic, Persian, and Kampo medicine, alongside an overview of nutritional regimens and their therapeutic potential. Other sections cover natural molecules such as flavonoids, saponins, coumarins, alkaloids, terpenes, polysaccharides, and several microbial natural products of relevant action against viruses. Final chapters cover nanotherapeutic approaches.This is a valuable resource for researchers and academics in the fields of herbal medicine, pharmacology, pharmacognosy and for professionals in the pharmaceutical industries and anyone interested in natural products and their application for therapeutic purposes.

  • Annual Reports in Medicinal Chemistry: Roadmaps

    • 1st Edition
    • Volume 62
    • English
    Annual Reports in Medicinal Chemistry: Roadmaps, Volume 62 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. This release provides a compendium of information on newly approved drugs and compounds entering late-stage clinical trials, making it a valuable resource for graduate students pursuing research in medicinal chemistry

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 63
    • English
    Progress in Medicinal Chemistry, Volume 63 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Specific chapters in this release include Harnessing conformational drivers in drug design, Recent Advances in the Medicinal Chemistry of Heterobifunctional Derivatives for Protein Homeostasis, and A Decade of Antimalarial Drug Discovery: New Targets, Tools and Molecules.

  • Quality Assurance Management

    A Comprehensive Overview of Real-World Applications for High Risk Specialties
    • 1st Edition
    • Gayathri De Lanerolle + 3 more
    • English
    Quality Assurance Management: A Comprehensive Overview of Real-World Applications for High Risk Specialties demonstrates how to best design and implement standard operating procedures (SOPs) to ensure protocol and regulation adherence. The book showcases similarities and differences between healthcare and academic quality assurance systems, resulting in counter-productivity and performance issues, in addition to regulatory inspection preparedness. It uses the processes and standards of the UK to demonstrate how to combine QA and research building into ‘building blocks’ that share a common pathway for effective project design, analysis and unbiased interpretation of collated data.This book fills a gap, providing original research in QA that especially focuses on specialist areas. It will be of use to research and clinical staff working in clinical research within healthcare, academia and industry.

  • Rang y Dale. Farmacología

    • 10th Edition
    • James M. Ritter + 4 more
    • Spanish
    Nueva edición del texto clásico en Farmacología y de referencia para los estudiantes de Medicina en el que se aborda de forma exhaustiva, pero clara y organizada el mecanismo de acción de los fármacos más comúnmente usados, tanto a nivel molecular o celular, como de los mecanismos fisiológicos sobre los que actúan.Se ha mantenido la organización general del libro, dividido en 6 grandes secciones en las que se ofrece una descripción de los efectos y usos de los diferentes fármacos junto con su acción sobre las vías de señalización subyacentes a todos los procesos fisiológicos que ocurren en el ser humano. En cuanto a las novedades, si bien todos los capítulos se han actualizado, algunos de ellos han sufrido grandes cambios. Así cabe destacar: Cap 5 (se han incluido un mayor número de fármacos RNA), Cap 24 (recientes avances en la medición de la presión de oxígeno), Cap 40 (se ha puesto el foco en el Alzheimer y la demencia vascular y la asociada a los cuerpos de Levy), Cap 43 (nueva sección destinada al tratamiento del dolor crónico), Cap 51 (nuevos diagramas que ilustran los lugares de acción de los antibióticos a nivel de los ribosomas), Cap 53 (información sobre el modo de replicación de los retrovirales y una sección específica de Covid19) y Cap 57 ( gran y amplia cobertura de los nuevos fármacos anticancerosos). Se ha introducido dos nuevos capítulos. Uno de ellos dedicado a la Farmacología ocular y otro dedicado al tratamiento farmacológico de la migraña en el que se incluyen los nuevos antagonistas de CGRP y su uso profiláctico para la migraña. La nueva edición incluye acceso al e-book en español en el que se incluye contenido adicional (casos clínicos y preguntas de autoevaluación) también en español.

  • Pharmacological Advances in Central Nervous System Stimulants

    • 1st Edition
    • Volume 99
    • English
    Pharmacological Advances in Central Nervous System Stimulants, Volume 99 in the Mechanisms, Therapeutic Uses, and Abuse of Stimulants series, showcases recent pharmacological progress investigating both therapeutic (ADHD, binge-eating and narcolepsy) and abuse aspects of a number of stimulants, some of which are long-standing (amphetamines, cocaine and nicotine) while others are emerging (cathinones). Specific chapters in this new release include Transgenerational Epigenetic Inheritance of Phenotypes Associated with Parental Exposure to Drugs of Abuse, Dysregulation Of Brain Cholesterol Homeostasis by Psychostimulants, Modeling Methamphetamine Use Disorder in Mammals: Sex Differences in Behavioral Consequences and Gene Expression, and much more.Additional sections focus on Second Generation Stimulants – Pharmacological and Clinical Advances in The Treatment of ADHD And Binge-eating disorder, Pharmacology Of Stimulant – Opioid Co-Use, Role Of Age and Sex in Determining the Risk For Adverse Consequences Following Exposure To Amphetamines, Modafinil, An Atypical CNS Stimulant, Modulators Of Nicotine Reward-Related and Reinforcement-Relate... Behaviors, Methamphetamine Effects on Peripheral Immune System, Post-Translational Mechanisms in Neurotransmitter Efflux, The Many Enigmas of Nicotine, Genetic Variation in The Neuregulin-Erbb Signaling Pathway And Substance Use Disorders, Pharmacology And Neurotoxicology of Synthetic Cathinones, and more.

  • Brody's Human Pharmacology

    • 7th Edition
    • Lynn Wecker + 1 more
    • English
    **Selected for 2026 Doody's Core Titles in Pharmacology**Brody’... Human Pharmacology, 7th Edition, is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives.What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 62
    • Jonathan Bentley + 1 more
    • English
    Progress in Medicinal Chemistry, Volume 62 provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors.

  • Natural Products

    • 1st Edition
    • Volume 61
    • English
    Natural Products, Volume 61 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on Chemical evolution of natural product structure for drug discovery, Fungal Metabolites, Polypharmacology of Natural Products, Glycopeptide Antibiotics, and Natural products-based drug discovery for the CNS.

  • New Approaches Towards Novel Antibacterial Agents

    • 1st Edition
    • Volume 60
    • English
    New Approaches Towards Novel Antibacterial Agents, Volume 60 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Privileged Scaffolds in Drug Discovery

    • 1st Edition
    • Bin Yu + 2 more
    • English
    Privileged Scaffolds in Drug Discovery is the most complete and up-to-date work in the area. Covering a wide range of privileged structures, it is a perfect reference for scientists involved in targeted drug development.The editors recruited experts from several prestigious Chinese institutions to cover the areas of antiviral drugs, chalcone, pyrimidine, (benz)imidazoles, natural product-derived privileged scaffolds, N-Sulfonyl carboxamides, kinase inhibitors, antitumor molecules, antineurodegenerativ... drugs, triazoles, oxazolidinone, indole and indoline scaffolds, tigliane diterpenoids, peptide and peptide-based drugs, quassinoids, and others including pseudonatural products, macrocycles, stable peptides and peptidomimetics. The book also explores scaffolds in drug molecules approved in recent years.Privileged Scaffolds in Drug Discovery is a complete reference for researchers in drug discovery and organic synthesis, in academic and corporate settings, who are investigating privileged structures upon which to base new drugs. Researchers in medicinal chemistry and chemical biology will also find the contents of this book valuable.

  • Bioactive Lipid Mediators in Cardiopulmonary Pharmacology

    • 1st Edition
    • Volume 97
    • English
    Bioactive Lipid Mediators in Cardiopulmonary Pharmacology, Volume 97 updates readers on topics surrounding Bioactive lipid mediators. These mediators are involved in a vast array of signaling pathways that regulate both physiological and pathophysiological responses. Chapters in this new release include Cyclooxygenases and Vascular Function, Cyclooxygenases and Platelet Function, Eicosanoids and Cardiomyopathies, Cytochrome P450 Bioactive Lipids in the Heart, Epoxide Hydrolase and Leukotoxin in the Heart and Lung, Role of cytochrome P450-epoxygenase and soluble epoxide hydrolase in the regulation of vascular response, Bioactive Lipids in Hypertension, Cytochrome P450 Metabolites and Angiogenesis, 20-Hydroxyeicosatetr... Acid and Vascular Function, and more. Other critical sections cover Cytochrome P450 Eicosanoids and the Brain, Omega-3 Oxylipids, Resolvins, Lipoxins and Inflammation, Endocannabinoids as Bioactive Metabolites, and Oxylipins and Aspirin Exacerbated Respiratory Disease.

  • Pharmaceutical Biotechnology in Drug Development

    • 1st Edition
    • Muhammad Sajid Hamid Akash + 3 more
    • English
    Pharmaceutical Biotechnology in Drug Development summarizes key concepts and the latest developments of biotechnology applied to the development of biopharmaceuticals. Chapters present a comprehensive collection of introductory biotechnology technologies and their modern concepts and cover pharmacokinetic and pharmacodynamic behavior of biopharmaceuticals and modification techniques of amino acids and nucleic acid. Other sections focus on topics such as gene therapy, immunological preparations and nanoparticles which are the major contributions of pharmaceutical biotechnology. Final chapters discuss emerging techniques in the field of pharmaceutical biotechnology to meet current patient and health care demand. This book is an essential reference useful for pharmaceutical scientists, clinicians and academic researchers who want easy access to up-to-date practices of pharmaceutical biotechnology. Corporate researchers will also benefit from this book’s succinct and objective content structure.

  • Rang & Dale's Pharmacology

    • 10th Edition
    • James M. Ritter + 6 more
    • English
    **Selected for 2026 Doody's Core Titles in Pharmacology**Rang and Dale’s Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years.Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required.This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing.

  • Clinical Trials and Tribulations

    • 1st Edition
    • Gayathri De Lanerolle + 2 more
    • English
    Clinical Trials and Tribulations evaluates the multiple layers of complexities around research management, also exploring current practices, challenges and future directions. The book provides answers to readers questions and problems through extensive use of real-world examples, case studies and lessons learned. Following an approach to provide pragmatic viewpoints as well as concepts and methodologies and its alignment with specific practices, the book explores paradigms between planning and conducting research in academia vs. healthcare vs. industry in the UK vs. Europe vs. America. It highlights practical solutions to real-world complex issues that have been documented by independent regulators. This will be an indispensable book for all staff working in clinical research within healthcare, academia and industry, as well as students intending to work in clinical trials.

  • DNA Interactions with Drugs and Other Small Ligands

    Single Molecule Approaches and Techniques
    • 1st Edition
    • Marcio Santos Rocha
    • English
    DNA Interactions With Drugs and Other Small Ligands: Single Molecule Approaches and Techniques provides the reader with all the main information, a "state-of-the-art" of sorts and an overall review of the field. There is no other book currently available that covers all these subjects together. On the contrary, the different subjects that are developed in this book are currently scattered in journal articles and other books.

  • Elemene Antitumor Drugs

    Molecular Compatibility Theory and its Applications in New Drug Development and Clinical Practice
    • 1st Edition
    • Tian Xie
    • English
    Elemene Antitumor Drugs: Molecular Compatibility Theory and its Applications in New Drug Development and Clinical Practice introduces natural anti-tumor drug elemene and systematic basic and clinical research. Basic principles of the compatibility theory of traditional Chinese medicine and the research and development process of the natural anti-tumor drug elemene under the guidance of this principle are introduced. In addition, the traditional extraction and separation of elemene and the new biosynthesis technology developed by the author's team are described. Then, the systematic anti-tumor mechanism research of elemene are introduced, including unique multi-target and comprehensive anti-tumor mechanisms and detailed mechanisms for treating specific tumors. Under the guidance of compatibility theory, clinical research on the combined application of elemene and different chemotherapeutic drugs has been further carried out, achieving positive results in clinical practice. Finally, the book also introduces the research and exploration of new drug delivery systems of elemene, as well as the structural modification and drug discovery progress taking elemene structure as the lead compound.

  • Advances in Extraction and Applications of Bioactive Phytochemicals

    • 1st Edition
    • Mihir Kumar Purkait + 2 more
    • English
    Advances in Extraction and Applications of Bioactive Phytochemicals presents comprehensive and systematic coverage of extraction techniques for bioactive phytochemical compounds and their delivery and therapeutic effectiveness. Sections focus on the pharmaceutical industry’s perspective, aiming at compiling recent advances of natural products in the field of drug delivery, including a brief overview of plant-based bioactive molecules, utilization of different plant elements for the extraction of phytochemicals, a compilation of conventional extraction approaches, advanced extraction methods, including Supercritical carbon-dioxide extraction, computational methods to improve production, drug delivery aspects of bioactive phytochemicals, their therapeutic effectiveness, and more. This book is a complete reference targeted at pharma researchers in academic and corporate environments and those willing to apply the most current extraction methods and health applications. Researchers in medicinal chemistry and chemical engineering will also benefit from this comprehensive resource.

  • Applications of Nanovesicular Drug Delivery

    • 1st Edition
    • Amit Kumar Nayak + 3 more
    • English
    Applications of Nanovesicular Drug Delivery provides thorough insights and a complete and updated discussion on the preparation, properties and drug delivery applications of various nanovesicles. This volume will discuss target-specific drug application, such as ocular, transdermal, nasal, intravenous and oral delivery. This title is a valuable resource for academics, pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical products and process development of tailored-made polysaccharides in drug delivery applications. Recently, there have been a number of outstanding nanosystems in nanovesicular carrier-forms (such as nanoemulsions, self-nanoemulsifying systems, nanoliposomes, nanotransferosomes, etc.), that have been researched and developed for efficient drug delivery by many formulators, researchers and scientists. However, no previously published books have covered all these drug delivery nanovesicles collectively in a single resource.

  • Allgemeine und spezielle Pharmakologie und Toxikologie

    • 13th Edition
    • Klaus Aktories + 3 more
    • German
    Wer mit „Aktories" lernt, versteht Das Standardwerk der Pharmakologie und Toxikologie in überarbeiteter 13. Auflage: das gesamte Wissen auf über 1.000 Seiten. Bewährt als erstklassiges Lehrbuch für Medizin- und Pharmaziestudierende... begehrt als Nachschlagewerk für Medizinier*innen und Pharmakolog*innen. Das gesamte Wissen der Pharmakologie und Toxikologie wird Ihnen hier verständlich und anschaulich erklärt und bringt Ihnen Sichherheit beim Lernen: Arzneimittelwirkunge... im Gesamtzusammenhang begreifen: Wirkmechanismen und pathophysiologische Bezüge in jedem Kapitel Zusammenhänge verstehen: Ausführliches Kapitel zur allgemeinen Pharmakologie und Toxikologie erleichtert Ihnen das Verständnis der speziellen pharmakologischen Zusammenhänge Praktische Relevanz: Empfehlungen zu Therapie und Dosierungen finden Sie in farbig hervorgehobenen Kästen Neu in der 13. Auflage: Hoch aktuelle Darstellung der Biologika (= das Gebiet der Pharmakologie, das am schnellsten wächst): signifikante Neuentwicklungen für die Tumortherapie, der Therapie rheumatischer Erkrankungen und anderer Autoimmunerkrankunge... der Therapie allergischer Erkrankungen und der Therapie der Psoriasis (Schuppenflechte) Bemerkenswerte Erkenntnisse bei der Einführung der SGLT-2-Inhibitoren (Sodium-Glucose-Like... 2) in der Diabetes-Typ2-Therap... Darstellung der vielfältigen Zusammenhänge von molekular-pharmakolo... Wirkungen der Arzneimittel und ihrer therapeutischen Anwendung (inklusive der mRNA-Technologie) Neue Arzneimittelentwickl... Ergänzung der IMPP-Arzneistofflist... (Markierung im Fließtext + eigenes Register)

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 61
    • David R. Witty + 1 more
    • English
    Progress in Medicinal Chemistry, Volume 61 provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors.

  • New Targets for the Treatment of Hypertension and Associated Diseases

    • 1st Edition
    • Volume 94
    • English
    New Targets for the Treatment of Hypertension and Associated Diseases, Volume 94 in the Advances in Pharmacology serial, highlights new advances in the field, with this new volume presenting interesting chapters on Cytochrome P450, 20-hydroxyeicosatetr... acid and GPR75 pathway in hypertension, Treatment of hypertension with soluble epoxide hydrolase inhibitors, Effects of allosteric modifiers of adenosine receptors in the heart, Orally active epoxyeicosatrienoic acid analogs in hypertension and renal injury, Drugs affecting the nitric oxide- cyclic GMP pathway in hypertension, Relaxin-2 and Serelaxin in renal and cardiac dysfunction in hypertension, and more.

  • Biochemistry of Drug Metabolizing Enzymes

    Trends and Challenges
    • 1st Edition
    • Muhammad Sajid Hamid Akash + 1 more
    • English
    Biochemistry of Drug Metabolizing Enzymes: Trends and Challenges is a complete and well-integrated reference on their mechanisms of action, their role in diseases, agents responsible for their deactivation, and their malfunction. Chapters explain the biochemistry of DMEs, including biochemical activation, functions, computational approaches, different contaminants on the action and function of DMEs, and describe the importance of DMEs in the drug development process. Conditions covered include metabolic diseases, cardiovascular diseases, neurological diseases, physiological diseases, xenobiotics and inflammatory responses, and their contribution in the malfunctioning of drug metabolizing enzymes. This book is the perfect resource for pharmacology and biochemistry researchers to understand the principles of DMEs. Researchers in the corporate environment will also benefit from the comprehensive list of diseases associated with malfunction of DMEs.

  • Brenner and Stevens’ Pharmacology

    • 6th Edition
    • Craig W. Stevens
    • English
    **Selected for 2026 Doody's Core Titles in Pharmacology**More detailed than an outlined review but less overwhelming than an encyclopedic reference, Brenner and Stevens’ Pharmacology, 6th Edition, focuses on the essential principles you need to know in a concise, easy-to-understand manner. Authored by Craig W. Stevens, PhD, this highly illustrated introductory text helps you learn and retain key information in pharmacology—taking you from course exams and the USMLE Step 1 right through to clinical practice. New and extensively revised content keeps you up to date with the latest pharmacologic mechanisms and applications.

  • Medical Pharmacology and Therapeutics

    • 6th Edition
    • Derek G. Waller + 1 more
    • English
    Medical Pharmacology & Therapeutics provides all the information medical and healthcare students need throughout their degree programme and beyond, including for professional qualifications such as the PSA.This all-round textbook covers basic pharmacology through to drug prescribing in clinical contexts, covering the pathogenic mechanisms of disease; drug actions, side effects, and the therapeutic principles of drug use. It takes a helpful systems-based approach that orders information according to body systems and disease areas, rather than by drug class.Now in its sixth edition, the book has been fully updated to include latest scientific understanding of drug action and administration and current best practice in prescribing medications, informed by the latest national guidelines.

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