Books in Pharmacology general

Providing foundational knowledge, this collection covers drug mechanisms, receptor pharmacology, and therapeutic principles. Supporting students, educators, and researchers, it features core concepts, emerging trends, and interdisciplinary approaches that underpin pharmaceutical science and clinical practice.

Integrating Artificial Intelligence with Virtual Screening
A New Era in Drug Discovery
1st Edition
Vivek Asati + 1 more
English
Integrating Artificial Intelligence with Virtual Screening: A New Era in Drug Discovery addresses the evolving landscape of drug discovery by combining traditional virtual screening with cutting-edge artificial intelligence technologies. This volume offers an interdisciplinary guide to AI-driven ligand and structure-based screening methods, including machine learning, deep learning, and generative models, thus enabling faster and more accurate identification of drug candidates. It covers mathematical models, computational workflows, and optimization strategies such as Pareto-based and physics-based approaches.Sections also discuss challenges in navigating ultra-large chemical libraries and present practical case studies that demonstrate real-world applications. Edited by leading researchers, the book provides authoritative insights suited for graduate students, researchers, and industry professionals. Users will be empowered by the latest tools and knowledge to innovate drug discovery pipelines and support the development of precision medicines and foster advancements in pharmaceutical sciences.
The Pharmacology of Obesity
1st Edition
Volume 107
English
The Pharmacology of Obesity, Volume 107 in the Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Obesity Therapeutic Landscape, Challenges, and Unmet Needs, Diagnosis and Evaluation of Obesity for Therapeutic Selection, When to use First-Generation Anti-Obesity Medications?, GLP-1 Receptor Agonists in our Clinics, Future Directions in Obesity Pharmacotherapy: Novel Targets and Pipeline Therapies, Destigmatizing Obesity: from language to the clinical environment, and much more.Additional chapters cover Role of Nutrition and physical Activity in the Therapy of Obesity, Behavioral and Lifestyle Strategies in Obesity Management and Post-Bariatric Follow-Up, The interpretation of Body-composition Metrics in Obesity, Digital Health, Technology, Artificial Intelligence, and Wearables in Obesity Care, Metabolic Aging and Obesity: how Physiology Changes with Age, Endoscopic Bariatric and Metabolic Therapies, and What Patients Could Benefit from Bariatric Surgery?
Pharmacology of T-Cell Therapies
1st Edition
Volume 106
English
Pharmacology of T-Cell Therapies, Volume 106 in the Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics in this new release include Enhancing persistence of therapeutic T cells, T cell manufacturing impacts on in vivo function, Transient T cell therapies, In vivo T cell therapies, T cell subsets for therapy, Engineering T cell metabolism to enhance therapeutic efficacy, and Tracking Therapeutic T cells In Vivo contacts.
Capsaicin, the Pungent Principle in Hot Pepper
From Basic Pharmacology to Therapeutic Applications
1st Edition
Arpad Szallasi
English
Capsaicin, the Pungent Principle in Hot Pepper: From Basic Pharmacology to Therapeutic Applications explores capsaicin's biological and pharmacological characteristics, from its discovery and isolation to its receptor identification and antagonists. The book's structure is divided into three sections, starting with the historical development of research on capsaicin. This foundational section provides a thorough understanding of the compound's journey from a simple pungent ingredient to a significant element in pharmacological studies. The second part of the book delves into capsaicin’s biological effects and pharmacology, covering areas such as nociception, pain, salivary secretion, body temperature regulation, and blood pressure regulation.Finally, the book examines the clinical applications of capsaicin, discussing potential future developments in desensitization, pain relief, injections, effects on the tumor microenvironment, appetite control, and longevity. This book is invaluable for pharmacology researchers and clinicians in pain management and cancer, offering insights into the unique characteristics and therapeutic potential of capsaicin.
The Science of Pharmacology
1st Edition
Jahangir Moini + 3 more
English
The Science of Pharmacology offers a detailed and contemporary exploration of medications, delving into the scientific principles behind drug actions and their therapeutic applications. It is an essential resource for students in pharmacology and pharmaceutical sciences, providing foundational knowledge on a wide range of topics. The book addresses the effects of drugs on various bodily systems, such as the nervous, respiratory, and cardiovascular systems, and also covers their impact on mental health and behavior. Beyond the core topics, the book also discusses special subjects like herbal medications and drug interactions.It includes valuable teaching materials, including test banks and quizzes, and offers comprehensive insights into toxicological treatments, making it an invaluable tool for both learning and teaching in the field.
Brain Shuttle Peptides: Development and Applications
1st Edition
Volume 105
English
Advances in Pharmacology, Volume 105, a new volume in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Introduction to brain shuttle peptides, In silico optimization of brain shuttle properties for passive diffusion, Shuttles derived from natural proteins, Shuttles derived from phage display, Chemically enhanced brain shuttle peptides, Brain delivery of gold nanoparticles, Brain delivery of lipid nanoparticles, Brain delivery of therapeutic proteins, In vitro BBB models for the study of brain shuttle transport, Physiological strategies for delivery across the BBB, and Polymeric Nanoparticles.
Machine Learning in Drug Development: Part 2
1st Edition
Volume 65
English
Machine Learning in Drug Development: Part Two, Volume 65 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this volume explore Transforming Modern Drug Discovery with Machine Learning – Applications in Ligand-based Drug Design, Optimizing Multi-Modal Drug Design Through Computational Pocket Mapping and Data Integration, Harnessing AI for Nucleic Acid Drug Discovery: Small Molecule Targeting DNA and RNA, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, and more.Additional section delve into Artificial Intelligence in the Development of Antiviral Drugs – Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery
Progress in Medicinal Chemistry
1st Edition
Volume 64
English
Progress in Medicinal Chemistry, Volume 64 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.
Machine Learning in Drug Development: Part 1
1st Edition
Volume 64
English
Machine Learning in Drug Development: Part One, Volume 64 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field. Chapters in this release include Artificial Intelligence in Small Molecule and Nucleic Acid Research: A Review, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, AI-aided Drug Development for Protein Degraders: Biology Validation, Disease-association, Drug Repurposing, Transforming Modern Drug Discovery with Machine Learning, Artificial Intelligence in the Development of Antiviral Drugs: Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery.
Comprehensive Toxicology
4th Edition
Charlene McQueen
English
Comprehensive Toxicology, Fourth Edition, Fifteen Volume Set continues the legacy that began with the first edition in 1997, serving as an indispensable reference for toxicology researchers. This edition focuses on understanding the mechanisms by which chemicals affect biological systems and cause adverse health effects. Edited by a distinguished editorial board and featuring 400 in-depth contributions from experts around the globe, this comprehensive work spans fifteen volumes and nearly 9,000 pages, covering all major organ systems and general principles of toxicology. This extensively revised edition includes around 30 new chapters on modern testing strategies and novel in vitro models, such as organ-on-a-chip systems.It also explores computational approaches, new risk and safety assessment methods, harmonization, artificial intelligence, and the microbiome. As the most authoritative resource in toxicology, it continues to support researchers, faculty, and students in toxicology, as well as professionals in medical, veterinary, food, environmental, chemical, and pharmaceutical industries and international regulatory agencies.