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Elsevier

Books in Life sciences

  • Special Volume on Kogia biology: Part 4

    • 1st Edition
    • Volume 106
    • English
    Special Volume on Kogia Biology: Part Four, Volume 106 presents reviews on all aspects of marine biology. Published since 1963, this serial updates on marine biology, fisheries science, ecology, zoology and biological oceanography. Topics include Stranding data of Kogia spp. from the seas around Japan, The biology of pygmy sperm whales (Kogia breviceps) from New Zealand waters, Age, growth and reproduction of pygmy (Kogia breviceps) and dwarf (K. sima) sperm whales stranded in South Africa, The fast lane revisited: life history strategy of Kogia spp, and Stomach content analysis of pygmy and dwarf sperm whales and its ecological implications: is there niche partitioning?

  • Machine Learning and Urban Health

    Advancing Wellness through Data Analytics
    • 1st Edition
    • Deepak Kumar + 3 more
    • English
    Machine Learning and Urban Health: Advancing Wellness through Data Analytics explores how advanced data analytics and machine learning are reshaping the future of urban wellness. As cities worldwide evolve into highly interconnected, technology-driven spaces, new opportunities—and challenges—emerge for ensuring sustainable urban health. This timely volume addresses the critical question: how can we harness the power of data to improve health outcomes in complex urban environments? From predicting disease outbreaks to identifying vulnerable populations and optimizing resource allocation, this book highlights how machine learning is transforming the public health landscape.Drawing on real-world case studies and diverse datasets—including environmental sensors, population health indicators, and urban infrastructure metrics—the book provides actionable insights for researchers, policymakers, urban planners, and public health professionals. It emphasizes not only technical innovation but also the ethical and equitable use of health data to reduce disparities and enhance quality of life for all city residents.

  • Advances in Virus Research

    • 1st Edition
    • Volume 127
    • English
    Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Biomedical Engineering - Part C

    • 1st Edition
    • Volume 410
    • English

  • Mitochondria Part B

    • 1st Edition
    • Volume 217
    • English

  • Next-Generation Non-Animal Protein Foods: Science, Technology, and Health for a Changing Food System

    • 1st Edition
    • Volume 124
    • English
    Advances in Food and Nutrition Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Agronomy

    • 1st Edition
    • Volume 204
    • English
    Advances in Agronomy, Volume 204, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Male Infertility

    From Pathophysiology to Clinical Management
    • 1st Edition
    • Rehana Rehman + 1 more
    • English
    Understand the latest science and clinical breakthroughs to master the diagnosis and treatment of male infertilityWork DescriptionMale Infertility: From Pathophysiology to Clinical Management offers an authoritative, accessible guide covering the biology, diagnosis, and treatment of male reproductive disorders. Edited by leading experts, this volume integrates cutting-edge research —including molecular mechanisms, proteomics, and emerging therapies —with practical clinical insights. Featuring contributions from international specialists, it addresses genetic, hormonal, environmental, and psychosocial factors influencing male fertility. With clear illustrations, evidence-based management strategies, and future-focused chapters on technologies like AI and regenerative medicine, this book is an essential resource for clinicians, researchers, and students seeking to deepen their understanding and improve patient care in reproductive medicine.Key FeaturesIntegrates the latest research, including emerging technologies like proteomics, assisted reproductive techniques (ART), and regenerative medicineFeatures illustrations, flow charts, summary tables, key points, and step-by-step procedures to facilitate understanding and applicationProvides a thorough foundation in male reproductive biology, infertility causes, diagnostics, and management strategies

  • Neurobiology of Depression

    Road to Novel Therapeutics
    • 2nd Edition
    • João L. de Quevedo + 2 more
    • English
    Neurobiology of Depression: Road to Novel Therapeutics, Second Edition follows the success of the first edition, synthesizing the basic neurobiology of major depressive disorder (MDD) with discussions on the latest research advances, including interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and novel optogenetic techniques revolutionizing depression research. This new edition includes comprehensive foundational understandings of the disorder and highlights recent advances, aiding advanced students and researchers in their understanding of MDD. The book introduces new chapters exploring groundbreaking topics such as the neurobiology of treatment-resistant depression, the antidepressant mechanisms of ketamine, and the link between depression and Alzheimer's disease. Additionally, it covers the neurobiology of suicide in depression, the impact of psychedelics as therapy, and the unique aspects of bipolar depression. This edition also examines computational models in depression, the neurobiology of psychotherapy, and the putative mechanisms of action for vagus nerve stimulation as a therapeutic approach. These additions help to provide a broader and more comprehensive understanding of depression and its treatment.

  • Molecular Mechanisms of Cancer Resistance

    Emerging Technologies and Therapeutic Strategies
    • 1st Edition
    • Ahmet Acar
    • English
    Molecular Mechanisms of Cancer Resistance: Emerging Technologies and Therapeutic Strategies explores innovative tools and strategies designed to address the critical issue of drug resistance in cancer treatment. This comprehensive volume is tailored for researchers, clinicians, and students, offering insights into the latest advancements and methodologies in the field. The book covers essential topics such as molecular mechanisms of drug resistance, the tumor microenvironment, and emerging technologies like single-cell analysis and computational modeling. Each chapter features contributions from leading experts, providing a multi-dimensional perspective on both foundational concepts and cutting-edge research.By engaging with this book, the academic audience gains access to groundbreaking research and therapeutic strategies that enhance understanding and practice. The knowledge acquired will inspire collaboration and innovation, ultimately contributing to more effective and personalized cancer treatment approaches.

  • Brain-Computer Interfaces (BCI)

    • 1st Edition
    • Volume 229
    • English
    Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Structure, Function, and Regulation of G Protein-Coupled Receptors Part B

    • 1st Edition
    • Volume 750
    • English
    G protein-coupled receptors constitute one of the largest classes of cell surface receptors in the human genome and drug targets for approximately one third of the currently prescribed medicines. The has been a tremendous advance in understanding the activation, signaling, and regulation of these receptors over the past couple of years using cellular, biochemical, structural, and pharmacological approaches. These two volumes of Methods in Enzymology cover these recent advances in the form of short overview of the key topics as well as step-by-step protocols developed to probe the functional attributes of these versatile receptors.

  • Clinical Brain Stimulation Part B

    • 1st Edition
    • Volume 309
    • English
    Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 90
    • English
    Advances in Microbial Physiology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Functioning Neuroendocrine Tumors and Paraneoplastic Endocrine Syndromes

    • 1st Edition
    • Volume 135
    • English
    Volume 135, Functioning Neuroendocrine Tumors and Paraneoplastic Endocrine Syndromes, provides a comprehensive and contemporary overview of the biology, clinical presentation, diagnosis, and management of hormone-secreting neuroendocrine neoplasms and endocrine paraneoplastic syndromes. Functioning neuroendocrine tumors (NETs) represent a unique group of neoplasms characterized by excessive hormone production, leading to diverse and often complex clinical syndromes that require a multidisciplinary approach. At the same time, paraneoplastic endocrine syndromes, resulting from ectopic hormone secretion by non-endocrine malignancies, remain important diagnostic and therapeutic challenges due to their rarity, heterogeneous manifestations, and significant impact on patient outcomes. This volume integrates recent advances in molecular biology, endocrine physiology, functional imaging, pathology, biomarkers, genetics, and precision medicine to provide an evidence-based approach to these disorders. Chapters cover the epidemiology, pathophysiology, diagnostic algorithms, localization techniques, medical and surgical treatment, peptide receptor radionuclide therapy, targeted therapies, and long-term follow-up of patients with functioning NETs, including insulinomas, gastrinomas, glucagonomas, VIPomas, somatostatinomas, ACTH-producing tumors, and other rare hormone-secreting neoplasms. In addition, the volume comprehensively reviews endocrine paraneoplastic syndromes such as ectopic Cushing syndrome, humoral hypercalcemia of malignancy, SIADH, tumor-induced hypoglycemia, and other ectopic hormone secretion syndromes, emphasizing early recognition and optimal multidisciplinary management.

  • Neurotoxicity of Microplastics and Nanoplastics

    • 1st Edition
    • Volume 17
    • English
    Neurotoxicity of Microplastics and Nanoplastics provides state-of-the-art reviews on topics in neurotoxicology. The book series addresses molecular and cellular mechanisms, experimental models, environmental and occupational toxicants, and the effects of neurotoxins on neurological disease. The series emphasizes critical synthesis of current knowledge while highlighting novel mechanistic insights.

  • Plant Tissue Culture

    Techniques and Experiments
    • 5th Edition
    • Sunghun Park
    • English
    Plant Tissue Culture, Fifth Edition offers a practice-driven introduction to one of the most influential experimental platforms in plant science. Combining established methodologies with contemporary advances in biotechnology, it demonstrates how cultured cells, tissues, and organs can be used to explore plant development and morphogenesis, propagate valuable germplasm, generate novel variation, and support crop trait enhancement.Structur... around a series of laboratory exercises, the book enables technical proficiency alongside an in-depth understanding of the biological principles that govern cellular growth, function, and regenerative responses. Readers are guided through the investigative techniques that have shaped the field, from micropropagation and embryo rescue to protoplast technologies and plant transformation, illustrating how in-vitro systems continue to serve as powerful tools for both discovery and application.This fully revised edition also discusses the expanding relationship between culture-based methods and molecular approaches, including genome editing and RNA interference. Building on decades of established principles and placing cutting-edge developments in the broader context of plant research and agricultural innovation, the volume highlights the continuing evolution of a discipline that remains central to unlocking and harnessing plant potential.

  • Aging and Troponin

    Clinical Implications and Uses Beyond Diagnosis
    • 1st Edition
    • Gary Tse + 3 more
    • English
    Aging and Troponin: Clinical Implications and Uses Beyond Diagnosis examines the multifaceted role of troponin in clinical medicine, with a special focus on aging. This comprehensive reference provides essential technical knowledge, diagnostic and prognostic applications, and model development insights from leading experts in clinical biochemistry, pathology, and epidemiology. The book emphasizes the impact of aging on troponin test results and their interpretation, addressing age-related disorders such as renal failure. Sections cover the technical aspects of troponin assays, comparing traditional and high-sensitivity assays and exploring point-of-care testing advancements.The book also examine age-related changes and intra- and inter-individual variability in troponin levels, focuses on diagnostic applications, including troponin as a biomarker for cardiac injury and dysfunction, and the effects of age, sex, and renal impairment on diagnostic sensitivity and specificity, and discusses troponin's prognostic value for mortality in various conditions, including heart disease, sepsis, and COVID-19, and its role as a marker of organ biological age. The final section offers cutting-edge insights into the clinical applicability of troponin testing, highlighting the benefits of incorporating high-sensitivity assays into clinical workflows and providing perspectives and age-related considerations from practicing physicians on implementation and evidence-based practice.

  • Evidence Based Diagnosis and Management of Testicular Tumors

    • 1st Edition
    • Axel Heidenreich
    • English
    Evidence Based Diagnosis and Management of Testicular Tumors is a comprehensive reference that addresses the current needs of urologists, oncologists, and related specialists involved in testicular cancer care. This book synthesizes the latest research, clinical guidelines, and expert insights to facilitate accurate diagnosis, staging, and personalized treatment strategies. It emphasizes a multidisciplinary approach, integrating pathology, molecular genetics, imaging, and surgical techniques, to optimize patient outcomes and minimize long-term toxicity. The contents are organized into key sections covering epidemiology, pathology, staging, diagnostic evaluation, disease management, and follow-up. Each chapter begins with case scenarios and interactive questions, fostering active learning and decision-making skills. The book also dedicates sections to rare tumors and pediatric cases, ensuring broad applicability across age groups and tumor types. Visual content, including figures, flow charts, tables, and videos, enhances comprehension and procedural training. This reference aims to bridge the knowledge gap in current testicular cancer management, providing practitioners with practical, guideline-conforming advice. It supports clinicians in delivering individualized, risk-adapted care, ultimately improving survival rates and quality of life for patients. By combining expert perspectives with evidence-based protocols, this book serves as an essential resource for advancing clinical practice in testicular oncology.

  • Implications of Artificial Intelligence in Next Generation Physiotherapy

    • 1st Edition
    • Manpreet Kaur + 3 more
    • English
    Implications of Artificial Intelligence in Next Generation Physiotherapy explores how artificial intelligence is transforming the future of physiotherapy across the entire continuum of rehabilitation. Covering musculoskeletal, neurological, cardiopulmonary, sports, paediatric, geriatric, women's health, and community-based physiotherapy, the book highlights how AI is reshaping clinical practice through intelligent assessment, precision rehabilitation, personalized treatment planning, predictive analytics, remote monitoring, and data-driven clinical decision-making.The book presents comprehensive coverage of emerging AI technologies, including machine learning, deep learning, computer vision, wearable sensors, robotics, virtual and augmented reality, digital twins, tele-rehabilitation, and intelligent clinical decision support systems. It also discusses workload monitoring, movement analysis, biomechanical assessment, functional outcome prediction, patient engagement, and continuous recovery tracking, supported by current research, real-world applications, and clinical case studies.Designed for researchers, clinicians, educators, students, and healthcare innovators, this book bridges the gap between cutting-edge artificial intelligence and evidence-based physiotherapy practice. By examining both current applications and future directions, it provides readers with the knowledge required to implement AI-driven innovations that enhance diagnostic accuracy, optimize rehabilitation outcomes, improve healthcare accessibility, and advance patient-centred care in the next generation of physiotherapy.

  • Metabolic Challenges in Cancer Treatment

    Precision Oncology in Diabetes and Radiotherapy
    • 1st Edition
    • Alok Raghav + 4 more
    • English
    Metabolic Challenges in Cancer Treatment: Precision Oncology in Diabetes and Radiotherapy presents an interdisciplinary academic reference that examines the complex interplay between diabetes mellitus, metabolic dysregulation, and radiotherapy outcomes in cancer patients. The book positions metabolic health as a critical determinant of therapeutic efficacy, toxicity, and survival, offering a timely contribution to precision oncology. The volume integrates endocrinology, radiation oncology, metabolism, and clinical medicine to explore pathophysiological mechanisms, radiotherapy‑induced metabolic alterations, glycemic control strategies, nutritional management, pharmacologic interactions, and personalized radiotherapy approaches. It combines mechanistic insights with clinical trial data, real‑world case discussions, and emerging research directions. For its academic audience, the book provides a unified framework that bridges bench‑to‑bedside translation, supports evidence‑based clinical decision‑making, and advances interdisciplinary research. It serves as a comprehensive resource for improving patient‑oriented outcomes and quality of life in cancer patients with metabolic comorbidities.

  • Wound Microenvironment Responsive Smart Dressing for Effective Healing

    • 1st Edition
    • Mohit Kumar + 4 more
    • English
    Wound Microenvironment Responsive Smart Dressing for Effective Healing presents a cutting-edge scientific exploration of phytoconstituent-bas... smart wound dressings engineered to accelerate and improve tissue repair. Bridging the therapeutic wisdom of traditional herbal medicine with advanced biomaterials, nanotechnology, polymer science, and bioengineering, this volume highlights how natural bioactive compounds can be transformed into clinically viable wound therapies. The book provides an integrated understanding of the molecular and cellular mechanisms governing wound healing, and demonstrates how stimuli-responsive delivery platforms—sensitive to pH, temperature, enzymes, ROS, or glucose—can enable precise, controlled release of phytochemicals directly at the wound site. These innovative systems overcome limitations of conventional formulations, such as instability, poor solubility, low bioavailability, and lack of targeted action. With contributions spanning smart hydrogels, nanocarriers, microneedles, 3D/4D printing, and AI-assisted wound monitoring, this multidisciplinary reference offers both foundational principles and translational guidance. Case studies and globally inclusive perspectives ensure broad relevance for researchers, clinicians, and formulation scientists working toward next-generation wound management solutions.

  • Endoscopic Transoral Surgical Approaches to the Skull Base

    • 1st Edition
    • Nyall London + 2 more
    • English
    Endoscopic Transoral Surgical Approaches to the Skull Base provides the first reference for endoscopic transoral surgical techniques and to improve education and training in endoscopic transoral skull base surgery. These approaches can be challenging; this book solves the problem by providing a collection of information regarding these surgical approaches and a dissection guide. This volume will act as a cadaveric surgical dissection guide to assist those interested in utilizing these surgical techniques

  • AI-Driven Robotics in Healthcare

    Ethical, Legal, and Implementation Challenges
    • 1st Edition
    • Rajiv Pandey + 3 more
    • English
    AI-Driven Robotics in Healthcare: Ethical, Legal, and Implementation Challenges presents a comprehensive reference in the rapidly evolving field of AI-driven medical robotics. Addressing the pressing demands of modern healthcare systems, this reference explores the intersection of machine learning, robotics, and healthcare delivery. It responds to the critical need for interdisciplinary understanding as healthcare providers, researchers, and policymakers navigate the complexities of AI integration. The reference is structured to cover foundational machine learning techniques, data processing, and deep learning architectures relevant to surgical robotics, followed by applications such as cognitive assistance, workflow automation, and anomaly detection. Implementation challenges including data privacy, system integration, and energy efficiency are examined alongside ethical, legal, and workforce implications. Contributions from international experts enrich the content with practical insights and case studies. This books benefits a diverse audience by bridging technical innovation with real-world clinical, regulatory, and policy considerations. It equips researchers, postgraduate students, healthcare professionals, and system integrators with the knowledge to responsibly adopt and manage AI robotics in healthcare, fostering safe, effective, and ethical technological advancement.

  • Artificial Intelligence in Healthcare

    • 2nd Edition
    • Adam Bohr + 1 more
    • English
    Artificial Intelligence in Healthcare, Second Edition shows where AI is delivering measurable value in medicine today, where it is failing, and what it takes to deploy it responsibly. Substantially rewritten since the first edition of 2020, it reflects the arrival of foundation models, multimodal data, autonomous and agentic systems, and the regulatory frameworks now shaping their use. Twelve chapters by leading practitioners cover AI-driven healthcare transformation and the gap between hype and real-world impact; next-generation drug discovery and molecular design; intelligent drug delivery and pharmaceutical innovation; oncology, from diagnostics to precision treatment pathways; medical imaging; medical devices; surgical intelligence; next-generation digital care; security, privacy and information sharing; insurance and personalised risk; and the ethical and legal questions that decide whether the machine can be trusted. Throughout, the emphasis is on evidence rather than promise: what problem each application solves, where it works in practice, where it fails, and what it means clinically and economically. Written for clinicians, healthcare leaders, industry and policymakers as well as researchers in computer science, data science, bioinformatics and biomedical engineering, it is a practical decision-making tool rather than a technical manual or an academic survey.

  • Understanding Mycotoxins

    Toxicity, Detection, Risk Assessment, and Prevention Strategies
    • 1st Edition
    • Vinay B. Raghavendra + 1 more
    • English
    Understanding Mycotoxins: Toxicity, Detection, Risk Assessment, and Prevention Strategies offers an in-depth exploration of their toxicological impact, detection techniques, and strategies for prevention and risk management. It addresses the critical health risks associated with mycotoxin exposure, including acute poisoning, carcinogenicity, and neurotoxicity, emphasizing the importance of accurate detection and effective mitigation measures. The book provides evidence-based insights into the mechanisms of mycotoxin toxicity, emerging threats, and the latest technological advances in analysis and detection. The book is structured into three detailed sections. The first section covers the fundamental aspects of mycotoxins, including their structures, biosynthetic pathways, sources of contamination, and health risks, supported by discussions on sampling, analytical techniques such as chromatography and spectroscopy, and the link between mycotoxins and diseases like cancer and neurological disorders. The second section delves into modern detection methods, highlighting advanced electrochemical sensors, immunoassays, biosensors, and innovative approaches utilizing machine learning, artificial intelligence, and nanotechnology for rapid and accurate identification of mycotoxins in various food matrices. The final section focuses on prevention and risk management, exploring detoxification strategies, mitigation techniques—including physical, chemical, biological, and emerging plasma and nanotechnology-based methods—and the regulatory frameworks that underpin safe food production and handling practices, aiming to reduce exposure and protect vulnerable populations globally.

  • Surgical Management of GERD

    • 1st Edition
    • Shahin Ayazi + 1 more
    • English
    Surgical Management of GERD provides a comprehensive and up-to-date reference on the modern surgical treatment of gastroesophageal reflux disease.Authored by a diverse and authoritative group of contributors, the book is organized into four sections covering foundational principles, primary anti-reflux procedures, complex and special scenarios, outcomes, technology, and future directions.By addressing both operative techniques and the underlying physiologic considerations, the volume serves as a practical guide for clinicians and trainees in foregut and esophageal disease, including practicing and academic surgeons, gastroenterologists, advanced endoscopists, residents, and fellows.

  • Artificial Intelligence in Medical Ultrasound

    • 1st Edition
    • Zhuhuang Zhou
    • English
    Artificial Intelligence in Medical Ultrasound is an authoritative reference that explores the integration of advanced AI methodologies within the field of ultrasound imaging. The book addresses the critical need for specialized knowledge on AI-driven ultrasound techniques, which are rapidly transforming diagnostic and therapeutic practices. It covers a broad spectrum of topics, including AI-assisted image processing, quantitative ultrasound, multimodal deep learning, and emerging models such as generative adversarial networks and physics-informed neural networks. The detailed table of contents delineates chapters authored by leading international experts, providing both foundational principles and cutting-edge research developments. The content is designed to serve researchers, engineers, and clinicians seeking to understand, develop, and deploy AI models in ultrasound applications. Its comprehensive scope ensures that readers will gain a deep understanding of the latest innovations, practical applications, and future directions in the field. This reference aims to facilitate the adoption of AI techniques in clinical settings, improve diagnostic accuracy, and accelerate the development of next-generation ultrasound technologies. Overall, it is an essential resource for advancing research, guiding clinical practice, and fostering innovation in medical ultrasound with artificial intelligence.

  • Nanoengineered Drug Delivery Systems for Oral and Head and Neck Cancer

    Targeting the Tumor Microenvironment
    • 1st Edition
    • Raghvendra Ashok Bohara
    • English
    Nanoengineered Drug Delivery Systems for Oral and Head and Neck Cancer: Targeting the Tumor Microenvironment explores innovative nanotechnologies designed to improve treatment outcomes for oral and head and neck cancers. The book integrates molecular design, nanotechnology, and clinical translation, emphasizing targeted drug delivery strategies that modulate the tumor microenvironment. It provides comprehensive coverage of tumor biology, early detection, molecular targets, and advanced delivery systems like liposomes and stimuli-responsive nanocarriers.The content also highlights emerging areas such as immune engineering, AI-assisted design, and clinical case studies, fostering a translational approach from laboratory research to clinical application. This resource benefits researchers, clinicians, and students by offering insights into cutting-edge nanomedicine, fostering interdisciplinary collaboration, and guiding future innovations in personalized cancer therapy and commercialization pathways.

  • Urinary Tract Infections

    Epidemiology, Immunopathology, Diagnosis and Treatment
    • 1st Edition
    • Ashish Jain + 2 more
    • English
    Urinary Tract Infections: Immunopathology, Diagnosis and Treatment is a comprehensive scientific reference that addresses the epidemiology, pathogenesis, and clinical management of UTIs.This volume explores the complex mechanisms underlying bacterial and nonbacterial urinary tract infections, emphasizing the role of host immune responses, microbiota interactions, and emerging diagnostic tools. The book covers a broad spectrum of topics, including the anatomy and physiology of the urinary tract, pathogen virulence factors, and the impact of antimicrobial resistance, providing a holistic understanding of UTI pathology. Its detailed chapters on clinical manifestations, prophylactic measures, and therapeutic strategies serve as an essential guide for clinicians, microbiologists, and researchers seeking current insights and future directions in UTI management. The volume also discusses innovative approaches such as vaccine development, probiotics, and novel therapeutics, aligning with the latest advances in precision medicine.This reference aims to bridge gaps between research and clinical practice, offering evidence-based recommendations and highlighting ongoing challenges. It is designed to support medical professionals, research scholars, and policymakers in improving patient outcomes and advancing scientific knowledge in urinary tract infections. Overall, this volume is an indispensable resource for those involved in infectious disease research, urology, and microbiology, fostering a deeper understanding of UTIs and promoting innovative solutions for their diagnosis and treatment.

  • Cuproptosis in Oncology

    Pathogenic Mechanisms and Emerging Therapeutic Opportunities
    • 1st Edition
    • Gourav Singh + 4 more
    • English
    Cuproptosis in Oncology: Pathogenic Mechanisms and Emerging Therapeutic Opportunities offers a comprehensive study of this novel form of regulated cell death driven by copper-induced mitochondrial stress, and its significance in cancer. The book begins with foundational chapters on the fundamentals of cuproptosis, its molecular mechanisms, and significance of copper homeostasis in cellular physiology, setting the stage for advanced discussions on its role in oncogenesis. Subsequent sections investigate cuproptosis in cancer progression, including how dysregulated cuproptosis influences tumor initiation, proliferation, metastasis, and therapy resistance. This is followed by an evaluation of innovative therapeutic approaches, including copper chelators, nanomedicine, small-molecule modulators, and combination therapies, highlighting their potential to revolutionize cancer treatment. The final section considers translational and clinical perspectives, including cuproptosis biomarkers for diagnosis and prognosis in oncology, clinical trials targeting cuproptosis, and future perspectives regarding the integration of omics, systems biology and precision medicine for therapeutic innovation. This volume unearths the critical role of copper homeostasis in tumor development and progression, laying the foundation for future translational advances. It serves as an invaluable resource for biomedical researchers including cell biologists, pharmacologists and oncologists, seeking to understand and target copper-dependent cell death pathways.

  • Novel Technologies for Dairy Foods

    • 1st Edition
    • Zuhaib F. Bhat + 2 more
    • English
    Novel Technologies for Dairy Foods provides a comprehensive overview of the latest advancements in the processing of milk and dairy products through both traditional and modern technologies. Recent innovations in engineering, materials science, and consumer sciences have led to significant research on emerging techniques such as pulsed electric fields, ultrasound, high-pressure processing, and 3D printing. These technologies not only enhance the quality and prolong the shelf life of dairy products but also facilitate the development of functional and designer foods tailored to special dietary needs, including those of geriatrics and individuals with swallowing difficulties. This book compiles and interprets a wealth of literature, summarizing industrial applications and advancements in processing technologies including cold plasma, pulsed electric field, ohmic heating and many more. Packaging systems, designer foods, and automation are covered, as well as the use of nano-preservatives with antioxidant and antimicrobial properties. This book is an essential resource for a diverse audience, including researchers, industry professionals, and students in the fields of food science, dairy technology, and nutrition. With contributions from renowned experts across the globe, readers will gain insights into the mechanisms by which novel technologies impact dairy quality and the latest trends in the industry.Novel Technologies for Dairy Foods serves as a critical reference for those seeking to deepen their understanding of innovative practices and their practical applications in the dairy sector.

  • Proteins in Camel Milk

    From Biochemistry to Therapeutic and Technological Advances
    • 1st Edition
    • Roua Lajnaf + 1 more
    • English
    Proteins in Camel Milk: From Biochemistry to Therapeutic and Technological Advances presents a comprehensive scientific examination of the structural, biochemical, and technological properties of camel milk proteins and their relevance in modern food systems, health applications, and industrial processes. This book contributes value to researchers and professionals by offering in-depth insights into the unique characteristics of camel milk proteins from Camelus dromedarius and Bactrianus, highlighting their potential as bioactive and functional ingredients in food and therapeutic products. With a strong emphasis on comparative protein biochemistry, this reference work explores the nutritional and therapeutic composition of camel milk, examining protein classes such as caseins, whey proteins, α-lactalbumin, lactoferrin, and immunoglobulins. It discusses their roles in antimicrobial, antioxidant, immunomodulatory, and anticancer activity, and highlights their potential in infant nutrition, functional foods, and medical applications. In addition, it addresses how microbial fermentation, thermal processing, drying, homogenization, and fouling influence protein structure, solubility, digestibility, and stability. Spanning five structured sections, the book includes chapters on the historical and nutritional value of camel milk, therapeutic and biotechnological relevance of its proteins, preservation and processing technologies, surface and emulsifying properties, and emerging non-food applications. It integrates recent research with practical considerations in dairy technology and product development, with special focus on sustainability, innovation, and commercialization.Th... book is a valuable resource for food scientists, dairy technologists, biochemists, academic researchers, postgraduate students, and industry professionals involved in functional food development, milk protein research, and dairy innovation, particularly those exploring the growing potential of camel milk in food and biotherapeutic sectors.

  • Site Specific and Global Epigenomic Editing

    Principles and Applications
    • 1st Edition
    • Volume 33
    • Feng C Zhou
    • English
    Site Specific and Global Epigenomic Editing: Principles and Applications, Volume 33 highlights the expanding role that epigenetics plays in pathogenesis, the full range of sites for possible epigenetic modification, and the potential to target these sites to modulate disease progression. The book answers key questions, including which of the hundreds of epigenomic marks and features are relevant, and which are likely to serve a role in regulating gene expression, cell behavior and phenotypic outcomes. This volume is the first to provide a thorough, conceptual introduction to epigenetic regulation and a thorough accounting of sites for possible epigenetic edits and disease modulation.Included protocols and applied case studies examine early disease targets and likely pathways of therapeutic significance while also outlining common challenges in the field. The book addresses its topic in a comprehensive, but accessible manner, highlighting practical tools and burning questions remaining in the field to enable fresh research.

  • A Manual for Endocrine Diagnoses, Therapies, and Research in Children and Young adults

    • 1st Edition
    • Constantine A. Stratakis
    • English
    A Manual for Endocrine Diagnoses, Therapies, and Research in Children and Young adults is an all-inclusive handbook of everything a practicing clinician should know about diagnosing and treating a pediatric endocrine disorder, including what is new and expected future predictions for clinical trials etc. It provides background information and research updates as well as the how to. This is a must have reference for scientists and researchers to be informed about the pediatric endocrine areas that they are researching on what is current state-of the-art in diagnosis and treatment.This book covers an expanding and interdisciplinary market of endocrinology with a special focus on pediatric endocrinology which provides not only a solid background of applicable science, but also the current impending development of diagnostic technologies, techniques, and procedures. Its core is focused on how clinical research affects clinical practice for not only Pediatrics, but also expand into growing research areas such as LGBTQ and aging.

  • Diagnosis and Treatment of Infectious Diseases

    • 1st Edition
    • Saeed Soleiman Meigooni
    • English
    Diagnosis and Treatment of Infectious Diseases summarizes practical content in infectious diseases using keys topics for better coding and grasping of material. The book's author uses his experience from over 15 years of teaching and working in infectious diseases in more than ten hospitals with thousands of patients as a backdrop. All of its contents use a clinical perspective for a wide range of audiences, such as medical students, general practitioners, nurses, and others. As infectious diseases are among the most common diseases, and a cause of death in many societies, they can create health challenges in developed and developing countries.Medical students have a limited time for infectious diseases rotation in their curriculum and may not learn many infectious diseases syndromes during their entire medical course. Also, due to the high volume of infectious disease subjects in textbooks which overlap symptoms and signs of many microorganisms, they may forget some of the materials. Therefore, access to a comprehensive compact book such as this one seems necessary for any medical staff.

  • Necroptosis

    A Programmed Cell Death Machinery in Human Health
    • 1st Edition
    • Pratyusha Mandal
    • English
    Necroptosis: A Programmed Cell Death Machinery in Human Health provides a comprehensive review of the evolving concepts of programmed cell death (PCD) machinery. The book traces the evolutionary origin of necroptosis, necroptotic proteins, and how the proteins contribute to necroptosis and other cell death pathways. It clarifies necroptosis as more than merely an alternate to extrinsic apoptosis but explores it as an inflammatory form of cell death interconnected with multiple death signaling that ultimately dictates physiological outcome. Coverage summarizes the role of the death pathway and proteins in mammalian health and disease as well as key diseases where they play contributing roles.The involvement of necroptosis in pulmonary diseases including activation during SARS-CoV2 infection is covered along with other gastroenteric diseases, cancer, and aging. Beyond conveying clinical knowledge, these topics will be of strong research interest to the biomedical bench scientist.

  • Social Determinants of Health in Surgery

    Research Methods and Clinical Review
    • 1st Edition
    • Steven A. Toms + 4 more
    • English
    Social Determinants of Health in Surgery: Research Methods and Clinical Review is a groundbreaking resource dedicated to examining the role of social determinants within surgical care. This book is designed for surgical trainees, healthcare providers, researchers, and policy administrators, offering a thorough exploration of how social factors impact surgical outcomes and practice. Featuring a detailed analysis of eleven key domains, it addresses the challenges and opportunities of integrating social determinants into surgical research and practice. The text provides essential guidance for those seeking to understand and improve patient outcomes through a broader, community-driven lens.In addition to its comprehensive coverage, the book delves into specialized topics such as big data analytics, ethical considerations, global health perspectives, pediatric surgical care, and clinical applications for research. It presents methodological guidance, including valuable tips and common pitfalls useful for readers at any stage of their surgical careers. The book also offers an in-depth review of social determinants research across ten major surgical specialties, highlighting significant trends, key studies, and current gaps in knowledge. Case studies and reflective interviews from experienced clinicians further enrich the reader’s understanding.

  • The Vaccine Book

    New Insights, Approaches, and Technologies
    • 3rd Edition
    • Fabio Bagnoli + 2 more
    • English
    The Vaccine Book: New Insights, Approaches and Technologies, Third Edition provides comprehensive information on the current and future world of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases such as AIDS, tuberculosis, and malaria. Edited by a new, highly experienced team of editors, the 3rd edition provides new approaches, design, and vaccine platform tools to develop vaccines quicker.This new edition is fully updated and designed for students, researchers, public health offcials, and all others interested in increasing their understanding of vaccines.

  • Cytokines

    Molecular Signals in Health and Disease
    • 1st Edition
    • Christopher Chang + 1 more
    • English
    Cytokines: Molecular Signals in Health and Disease offers a detailed guide to cytokines, their molecular mechanisms and impact on disease. The book is divided into four sections, first considering the fundamentals of cytokines including structural and functional classification, cytokine receptors, chemokines, and pro-inflammatory and anti-inflammatory cytokines. The book moves on to discuss the mechanisms of cytokines in disease, including genetics of cytokines, signaling pathways, and interaction between cytokines and cells. The third section explores cytokine-related diseases, including allergies, immunodeficiency disorders, rare diseases, cancer and impact in specific organ systems. Finally, the book closes with a section on cytokine release syndrome.This book acts as a comprehensive reference on this significant molecule and its role in cellular function and the development of disease and disorders. It is ideal for researchers in the fields of molecular biology and immunology, and those looking to investigate the significance of cytokines in disease pathogenesis and potential therapeutic intervention.

  • Microscopy in the Life Sciences from 1650 to the Present

    • 1st Edition
    • Joel B. Sheffield
    • English
    Microscopy in the Life Sciences from 1650 to the Present explores the transformation of the microscope and its applications and techniques over the course of history, illustrating how progress in optics and microscope design has informed our growing knowledge of cellular life. Beginning with early observations of cellular structure, the book tracks the movement towards understanding of cell biology and pathology, considering the changing landscape of microscopy, lens development, and limitations and challenges tackled. Users will also find content on recent advances, including fluorescence studies and the use of computational procedures to assemble images of individual molecules. This book traces the evolution of understanding that scientists have had regarding cellular life and how comprehension of this has been supported by the development of the microscope. It considers a range of experts central to its progression over the years, including Schleiden, Schwann, Abbe, Schott and Zeiss, and is a useful reference for researchers working with microscopy techniques across the biological sciences.

  • Microplastics and the Hidden Threat to Human Reproduction

    Plastic Peril
    • 1st Edition
    • Nimra Afzal + 1 more
    • English
    Microplastics and the Hidden Threat to Human Reproduction: Plastic Peril explores the intricate relationship between microplastics and reproductive health, delving into the sources and distribution of microplastics in the environment, human exposure routes, associated risks, the toxicological effects on reproductive health, potential connections to fertility, endocrine disruption, and developmental consequences due to maternal exposure. It includes impacts on both male and female reproductive health, risks during pregnancy, population-level health concerns, strategies for mitigating microplastic exposure, and the policy and regulatory frameworks surrounding this issue. The book also provides insights into the future direction of research and public health initiatives.In essence, it explores how tiny microplastic particles can have significant and far-reaching consequences on human reproductive health, making this a vital and emerging area of concern. This is a comprehensive resource for anyone interested in understanding the various aspects of the microplastics-reprod... health connection and a go-to reference for researchers, healthcare professionals, policymakers, and concerned individuals.

  • Water and Hydration in Health and Disease Prevention

    • 1st Edition
    • Rajkumar Rajendram + 2 more
    • English
    Water is one of the most fundamental needs sustaining human life. In the human body, hydration allows for the balance of electrolytes and the functioning of the kidneys, cardiovascular system, the brain, and more. For athletes, water and hydration are crucial in maximizing performance and preventing dehydration. At the same time, not all water is fit for purpose. Consideration must be given to water contaminated with heavy metals or organic chemicals in some communities. Water and Hydration in Health and Disease Prevention compiles the latest research on water in human health and connects otherwise scattered information into one comprehensive resource. Just as water is involved in nearly every aspect of life on earth, its study is vast and interdisciplinary, spanning fields such as environmental sciences, physiology, molecular biology, endocrinology, clinical sciences and other disciplines. Water and Hydration in Health and Disease Prevention will serve as an invaluable resource to researchers, clinicians, and students across all these fields.

  • Machine Learning in Cardiovascular Biomechanics

    Function, Diagnosis, and Prediction
    • 1st Edition
    • Reza Avazmohammadi + 1 more
    • English
    Machine Learning in Cardiovascular Biomechanics: Function, Diagnosis, and Prediction serves as a state-of-the-art reference of the methods and models published in the literature to highlight the current difficulties and encourage further exploration of applications of machine learning to cardiovascular biomechanics. This volume is a valuable asset for researchers and students attempting to address problems in cardiovascular mechanics using machine learning techniques as a reference to previously attempted and successful methods.

  • 3D Bioprinting and Bioinks for Regenerative Engineering

    Current Concepts and Future Advances
    • 1st Edition
    • Anthony Atala + 1 more
    • English
    3D Bioprinting and Bioinks for Regenerative Engineering: Current Concepts and Future Advances covers bioinks and their associated materials, design formulations, biological interactions, commercial products, and diverse applications in regenerative engineering of various tissues and organs. Part I lays the foundation for bioink concepts and their significance. Part II delves into various 3D printing technologies that enable the creation of complex biological structures. Part III focuses on the fundamentals of bioinks—critical materials that play a key role in printing viable tissues. In Part IV, attention shifts to the process of printing and the development of tissue and organ constructs.Finally, Part V addresses regulatory considerations and offers insights into future perspectives, emphasizing the challenges and opportunities ahead as the field continues to evolve. As the field is on the verge of a new era in engineering tissues, and tissue/body on a chip technologies will play a central role, bioinks are becoming a multidisciplinary field involving materials science, cell biology, biofabrication, and clinical applications. By combining cutting-edge research, practical applications, and expert contributions, this book will become an indispensable resource for both newcomers and experienced professionals.

  • Atlas of Heart and Vascular Pathology

    • 1st Edition
    • E. Rene Rodriguez + 1 more
    • English
    Atlas of Heart and Vascular Pathology presents detailed knowledge on how the normal heart structure can adapt to physiologic processes and how this adaptation can progress into pathologic states. In modern practice there are many interventions available to address diverse structural components of the heart and vascular systems (coronary arteries, valves, pericardium, the heart muscle itself, and vessels). Many such interventions are demonstrated in this atlas, along with the complications of such interventions. This resource helps readers understand the anatomical features and landmarks of the cardiac structures affected by pathologic processes, or by interventions and surgical procedures.In addition, it can help cardiovascular imagers and radiologists evaluate anatomic structures and interpret pathologic alterations. The book's authors illustrate with clarity common aspects of cardiovascular anatomy and pathology useful to medical and non-medical professionals who work on cardiovascular medical, surgical, technical and scientific fields. It is an indispensable reference to understanding the three-dimensional architecture of the heart to further understand how disease or pathologic processes affect its function.

  • Composting Science and Technology

    Fundamentals, Innovations, and Emerging Applications
    • 1st Edition
    • Sonia Tiquia-Arashiro
    • English
    Composting Science and Technology: Fundamentals, Innovations, and Emerging Applications provides a comprehensive examination of the scientific principles, technologies, and emerging innovations shaping modern composting. The book examines the biological, chemical, and physical processes underlying organic matter decomposition, with particular emphasis on microbial activity, nutrient transformations, process optimization, and compost quality. Through interdisciplinary perspectives and case studies, it connects fundamental composting science with the management and technological approaches used to improve process performance and product quality.Beyond established practices, the book explores advances in composting technologies, process monitoring and control, microbial management, biochar-assisted composting, and other emerging approaches to organic waste valorization. It also examines the role of composting in sustainable waste management, soil health, nutrient recycling, greenhouse gas management, and the circular economy, while addressing current challenges and future directions for composting science and technology.

  • Decellularization Technology in Regenerative Medicine and Tissue Bioengineering

    • 1st Edition
    • Ekaterine Berishvili + 2 more
    • English
    Decellularization Technology in Regenerative Medicine and Tissue Bioengineering, Volume Five in the Regenerative and Transplant Medicine series, captures recent progress and future directions in decellularization technology, addressing current challenges and exploring potential clinical applications. As organ transplantation remains the gold standard for treating various end-stage tissue and organ failures, this book addresses the use of cells, biomaterials, and bioactive molecules to restore or replace damaged tissues and organs. The book brings together contributions from leading experts in the field, providing a valuable resource for researchers, clinicians, and students involved in regenerative medicine and tissue engineering.As decellularization technology stands at the forefront of these efforts, offering numerous advantages over traditional transplantation methods, this book is a must-have reference.

  • Advanced and Sustainable Biotechnologies from Fungi

    Functional Foods and Nutraceutical Production
    • 1st Edition
    • Pragya Tiwari + 1 more
    • English
    Advanced and Sustainable Biotechnologies from Fungi: Functional Foods and Nutraceutical Production provides insights into existing and emerging fungal biotechnologies, along with advances in high-throughput technologies to enhance the sustainable production of bio-based functional foods and nutraceuticals of fungal origin. Focusing on the emerging, global concern of hunger and malnutrition, this book explains how fungi-based biotechnologies offer prospective solutions to address the global food shortage using functional foods and nutraceuticals. Chapters cover the major portion of novel sources and various biotechnological approaches used for the production of functional foods and nutraceuticals from microorganisms and mushrooms and their applications in the industry. In addition, the book includes the existing and emerging biotechnological trends and approaches in enhanced production of Functional food and Nutraceuticals of fungal origin, such as Omics-guided advances, computational strategies, and biotechnological tools. 3D printed fungal food products, and social, ethical, and regulatory aspects of functional food and nutraceutical products are also discussed. Authored by a team of experts in the field of fungi biotechnology, this book serves as a reference material for food microbiologists, food scientists, and pharmaceutical professionals for the development of new functional foods and nutraceuticals.

  • Sustainable Livestock Nutrition through Alternative Feed Ingredients

    • 1st Edition
    • Prabhat Khanal + 2 more
    • English
    Sustainable Livestock Nutrition through Alternative Feed Ingredients synthesizes the latest knowledge on alternative feed ingredients in livestock diets. With the use of sustainable, low-waste, and circular feed ingredients, livestock can gain essential key nutrients while reducing their environmental impact. Through meticulous research and practical insights, the book explores alternative proteins and nutritional sources for a variety of animals. Cutting-edge, low-impact ingredients, including insects, algae, microalgae, seaweed, and freshwater plants are covered and compared. Written and edited by an international team of experts, and with a focus on enhancing animal health and welfare while minimizing environmental impact, this book serves as a vital resource for researchers, farmers, students, and policymakers.

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