Books in Developmental biology

Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer - Part B

1st Edition
Volume 397
October 1, 2025
Lorenzo Galluzzi + 1 more
English

Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer Patients, Part B, delves into the crucial role of circulating biomarkers in cancer diagnosis and treatment monitoring. Specific chapters in this new release include Circulating biomarkers for diagnosis and response to therapies in cancer patients, Identification of circulating tumor DNA as a biomarker for diagnosis and response to therapies in cancer patients, Identification of cell-free circulating epigenomic biomarkers for early diagnosis and response to therapies in breast cancer patients, Expanding frontiers in liquid biopsy-discovery and validation of circulating biomarkers in renal cell carcinoma and bladder cancer, and much more.This comprehensive work explores the various types of biomarkers, their significance in early cancer detection, prognostication, and evaluation of therapeutic responses. It covers cutting-edge research on circulating tumor cells, cell-free DNA, exosomes, and other biomarkers that can revolutionize cancer management. Additionally, it discusses the challenges, advancements, and future prospects of utilizing circulating biomarkers in personalized cancer care.

Animal Models of Disease Part D

1st Edition
Volume 197
September 1, 2025
Lorenzo Galluzzi + 3 more
English

Animal Models of Disease, Part D, Volume 197 in the Methods in Cell Biology series presents significant advancements in understanding disease mechanisms through animal models. This volume features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

Cytokine-Based Immunotherapy - Part A

1st Edition
Volume 396
September 1, 2025
Pedro Berraondo + 2 more
English
Hardback
9 7 8 0 4 4 3 2 9 7 2 6 7
eBook
9 7 8 0 4 4 3 2 9 7 2 7 4

Cytokine-Based immunotherapy, Volume 396, Part A delves into the intricate world of cytokines, vital signaling proteins that orchestrate the immune response and their pivotal role in modulating various immune functions. From their fundamental mechanisms to their therapeutic applications, this book offers a thorough examination of the latest trends and developments in leveraging cytokines for immunotherapy. The book includes chapters such as Cytokine-driven cancer immune evasion mechanisms, which explores how cytokines contribute to cancer cells' ability to evade the immune system. Cytokine-based immunotherapy in hematolymphoid malignancies is also explored, discussing the use of cytokines in treating blood cancers.Targeting TNF-alpha examines the immunotherapeutic approach for alleviating neuropathic pain. The key role of immunomodulatory cytokines for the development of novel nk cell-based cancer therapies focuses on the importance of cytokines in developing new cancer treatments. Finally, complexities in the clinical development of TGFβ inhibitors covers the challenges in creating inhibitors for TGFβ.

The Emerging Genomic Landscape of Complex Immune-Mediated Traits

1st Edition
Volume 114
August 1, 2025
Juliana Miranda Cerqueira
English
Hardback
9 7 8 0 4 4 3 2 2 4 1 5 7
eBook
9 7 8 0 4 4 3 2 2 4 1 6 4

The Emerging Genomic Landscape of Complex Immune-Mediated Traits, Volume 114 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Unraveling the Interplay of Genetic Variants and Epigenetic Signatures in Complex traits, Crosstalk between T Cell Gene Regulation and Intestinal Epithelial Cells: Insights into Mucosal Immunity, Understanding the link between regulatory RNA regions and genomic variation with coeliac disease, Interplay Between the Host Genome, Autoimmune Disease and Infection, and Organoids and gut-on-chip as powerful tools to model the genetics of intestinal mucosal inflammation.

The Microbiome in Cancer and Autoimmunity - Part B

1st Edition
Volume 395
August 1, 2025
Manisha Singh
English
Hardback
9 7 8 0 4 4 3 3 1 7 0 8 8
eBook
9 7 8 0 4 4 3 3 1 7 0 9 5

Microbiome in Cancer and Autoimmunity - Part B, Volume 395 offers a comprehensive exploration of the intricate relationship between the human microbiome and the development of cancer and autoimmune diseases. Delving into cutting-edge research and clinical insights, this groundbreaking work elucidates the role of microbial communities in influencing immune responses, disease pathways, and therapeutic outcomes. Specific chapters cover the Effect of Microbial Dysbiosis on Autoimmune-Associated Inflammation, Gut Microbiota and Systemic Immune Responses in Cancer, The role of microbiome in gastrointestinal cancer, Cancer and Microbiome-Targeted Therapies, Autoimmune disease and Microbiome Targeted Therapies, and the Effect of Diet and Lifestyle on Microbiome Composition.

Novel Genetic Pathways Associated to Energy Homeostasis Impairments

1st Edition
Volume 113
July 1, 2025
Marc Schneeberger
English
Hardback
9 7 8 0 4 4 3 2 3 7 4 4 7
eBook
9 7 8 0 4 4 3 2 3 7 4 5 4

Novel Genetic Pathways Associated to Energy Homeostasis Impairments, Volume 113 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Advances in Metabolism: Energy Balance Circuitry, Advances in Metabolism: Diabetic Retinopathy, From Metabolomics to Energy Balance Physiology, Advances in Metabolism: Prader-Willi Syndrome, Neural Mechanisms and Health Implications of Food Cravings During Pregnancy, Advances in Metabolism: Diabetes, Advances in Metabolism: Cachexi, and Parkinson’s Disease and Metabolic Disorders: Understanding Their Shared Co-Morbidity Through the Autonomic Nervous System.

The Microbiome in Cancer and Autoimmunity - Part A

1st Edition
Volume 394
July 1, 2025
Manisha Singh
English
Hardback
9 7 8 0 4 4 3 3 1 7 0 6 4
eBook
9 7 8 0 4 4 3 3 1 7 0 7 1

Microbiome in Cancer and Autoimmunity - Part A, Volume 394 offers a comprehensive exploration of the intricate relationship between the human microbiome and the development of cancer and autoimmune diseases. Delving into cutting-edge research and clinical insights, this groundbreaking work elucidates the role of microbial communities in influencing immune responses, disease pathways, and therapeutic outcomes. From deciphering the molecular mechanisms underlying microbiome-host interactions to unraveling the impact of dysbiosis on disease progression, the book provides a multifaceted analysis of the microbiome's pivotal role in cancer and autoimmunity.With contributions from leading experts in the field, this book serves as a pivotal resource for researchers, clinicians, and healthcare professionals seeking to understand and harness the therapeutic potential of the microbiome in combating cancer and autoimmune conditions.

Circadian Rhythms in Health and Disease

1st Edition
Volume 393
June 1, 2025
Valentina Sica
English
Hardback
9 7 8 0 4 4 3 2 9 6 8 2 6
eBook
9 7 8 0 4 4 3 2 9 6 8 3 3

Circadian Rhythms in Health and Disease, Volume 393 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Circadian Rhythms in Cardiac Health and Disease, Liver as a nexus of daily metabolic cross talk, Non-rhythmic modulators of the circadian system: A new class of circadian modulators, The emerging role of circadian rhythms in exosome-mediated cellular crosstalk, Circadian rhythms and muscle health, and Output circuits from the suprachiasmatic nucleus controlling diverse physiological functions.

Circulating Tumor Cells, From Biotech Innovation to Clinical Utility Part B

1st Edition
Volume 392
May 1, 2025
Carolina Reduzzi + 2 more
English
Hardback
9 7 8 0 4 4 3 1 3 6 5 5 9
eBook
9 7 8 0 4 4 3 1 3 6 5 6 6

Circulating Tumor Cells, From Biotech Innovation to Clinical Utility Part B, Volume 392 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Circulating Tumor Cells in Lung Cancer: integrating stemness and heterogeneity to improve clinical utility, Multi-omic Features and Clustering Phenotypes of Circulating Tumor Cells Associated with Metastasis and Clinical Outcomes, CTCs in CRC: updates, Proteomics and post-translational modification analysis in CTCs, Latest advances of CTC studies in prostate cancer, and Epigenetics and CTCs: new biomarkers and impact on tumor biology.

Insect Ecomorphology

1st Edition
February 25, 2025
Oliver Betz
English
eBook
9 7 8 0 4 4 3 1 8 5 4 5 8

Insect Ecomorphology: Linking Functional Insect Morphology to Ecology and Evolution offers up-to-date knowledge and understanding of the morphology of insects and the functional basis of their diversity. This book covers the form and function of insect body structures in relation to their physiological performance capabilities, biological roles, and evolutionary histories. Written by international experts, the book explores the ecomorphology of functional systems such as insect feeding, locomotion, sensing, and egg laying. The combination of conceptual and review chapters, methodological approaches, and case studies enables readers to delve into active research fields and to gain an understanding of the form-function-performance paradigm.This book uncovers key structures of the various regions of the insect body, elucidates their function, and investigates their ecological and evolutionary implications. Insect Ecomorphology is thus a vital resource for entomologists, biologists, and zoologists, especially those seeking to understand more fully the morphology and physiological impacts of insects in correlation to their environments and to evolution.

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health