Books in Protein structure and synthesis

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Protein Misfolding in Neurodegenerative Diseases

• 1st Edition
• March 1, 2025
• Neha Gogia + 2 more
• English
• Paperback 978-0-443-18716-2

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• eBook 978-0-443-18717-9

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Protein Misfolding in Neurodegenerative Diseases is a comprehensive review of proteome homeostasis in neurons, and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson’s disease, ALS, Creutzfeldt-Jakob disease, and more.

Computational Intelligence in Protein-Ligand Interaction Analysis

• 1st Edition
• March 22, 2024
• Bing Wang + 2 more
• English
• Paperback 978-0-12-824386-2

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• eBook 978-0-12-824435-7

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Computational Intelligence in Protein-Ligand Interaction Analysis presents computational techniques for predicting protein-ligand interactions, recognizing protein interaction sites, and identifying protein drug targets. The book emphasizes novel approaches to protein-ligand interactions, including machine learning and deep learning, presenting a state-of-the-art suite of skills for researchers. The volume represents a resource for scientists, detailing the fundamentals of computational methods, showing how to use computational algorithms to study protein interaction data, and giving scientific explanations for biological data through computational intelligence. Fourteen chapters offer a comprehensive guide to protein interaction data and computational intelligence methods for protein-ligand interactions.

Encyclopedia of Biological Chemistry

• 3rd Edition
• July 29, 2021
• Joseph Jez
• English
• Hardback 978-0-12-819460-7

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• eBook 978-0-12-822040-5

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Encyclopedia of Biological Chemistry, Six Volume Set has always been characterized by its unique and comprehensive content. Since publication of the 2nd edition, many important discoveries have been made leading to novel concepts in several areas of biochemistry, and new technologies have advanced our understanding of key processes of life. All of these advances are included in the new and expanded third edition. With its 6 volumes, this is the most up-to-date and complete resource on biochemistry and molecular biology, provided through contributions by leading experts in the field.

RNA-Based Regulation in Human Health and Disease

• 1st Edition
• August 19, 2020
• Rajesh Pandey
• English
• Paperback 978-0-12-817193-6

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• eBook 978-0-12-817194-3

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RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics.

Chromatin Proteins and Transcription Factors as Therapeutic Targets

• 1st Edition
• Volume 107
• February 17, 2017
• Rossen Donev
• English
• Hardback 978-0-12-812390-4

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• eBook 978-0-12-812391-1

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Chromatin Proteins and Transcription Factors as Therapeutic Targets, the latest volume in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

Neurotrophins

• 1st Edition
• Volume 104
• February 15, 2017
• Gerald Litwack
• English
• Hardback 978-0-12-812263-1

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• eBook 978-0-12-812264-8

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Neurotrophins, the latest volume in the Vitamins and Hormones series first published in 1943, and the longest-running serial published by Academic Press, provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions, and the biological actions of neurotrophins related to clinical conditions and disease. Each volume is thoroughly reviewed and focuses on a single molecule or disease that is related to vitamins or hormones, with the topic broadly interpreted to include related substances such as transmitters, cytokines, growth factors, and others.

Early Stage Protein Misfolding and Amyloid Aggregation

• 1st Edition
• Volume 329
• January 18, 2017
• Massimo Sandal
• English
• Hardback 978-0-12-812251-8

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• eBook 978-0-12-812252-5

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Early Stage Protein Misfolding and Amyloid Aggregation, Volume 329, the latest in the International Review of Cell and Molecular Biology series presents comprehensive reviews and current advances in cell and molecular biology, including articles that address the structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a worldwide readership and maintains a high standard by publishing invited articles on important and timely topics as authored by prominent cell and molecular biologists.

Biomarkers of Kidney Disease

• 2nd Edition
• November 8, 2016
• Charles L. Edelstein
• English
• Hardback 978-0-12-803014-1

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• eBook 978-0-12-803035-6

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Biomarkers of Kidney Disease, Second Edition, focuses on the basic and clinical research of biomarkers in common kidney diseases, detailing the characteristics of an ideal biomarker. The latest techniques for biomarker detection, including metabolomics and proteomics are covered in the book. This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation, and preeclampsia. New chapters include biomarkers of cardiovascular disease in patients with CKD, biomarkers of Polycystic Kidney Disease, and biomarkers and the role of nanomedicine.

Conquering RAS

• 1st Edition
• August 11, 2016
• Asfar Azmi
• English
• Hardback 978-0-12-803505-4

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• eBook 978-0-12-803541-2

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Conquering RAS: From Biology to Cancer Therapy provides introductory knowledge on how modern RAS biology is taking shape in light of newer technological development. Each chapter is written in a manner that emphasizes simplicity and readability for both new investigators and established researchers. While RAS biology has been intensively studied for more than three decades, we are yet to see any effective therapeutics that could interfere in the signaling cascade regulated by this master oncogene. The book covers topics ranging from basic RAS biology, to translational biology and drug discovery applications. These topics will be appealing to basic researchers working in labs who seek deeper understanding of the modern concepts in RAS research. On the other side, the oncologist at the patient’s bedside will find the book useful as they routinely face the daunting task of treating patients that predominantly have a disease driven by oncogenic KRAS.

Ion Channels as Therapeutic Targets, Part B

• 1st Edition
• Volume 104
• March 29, 2016
• Rossen Donev
• English
• Hardback 978-0-12-804826-9

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• eBook 978-0-12-805242-6

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This volume is the second part of the thematic on Ion Channels as Therapeutic Targets. The popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists, brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.