Cytoskeletal Proteins in Neurodegenerative Diseases
- 1st Edition, Volume 150 - March 30, 2026
- Latest edition
- Editors: Subashchandrabose Chinnathambi, Rossen Donev
- Language: English
Cytoskeletal Proteins in Neurodegenerative Diseases, Volume 150 covers the pivotal roles that cytoskeletal proteins play in the onset and progression of neurodegenerative disord… Read more
Description
Description
Cytoskeletal Proteins in Neurodegenerative Diseases, Volume 150 covers the pivotal roles that cytoskeletal proteins play in the onset and progression of neurodegenerative disorders. The book explores the structure, function, and dynamics of key cytoskeletal components—including microtubules, actin filaments, and intermediate filaments—and examines how their dysfunction contributes to diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis (ALS). Chapters in this new release include Cytoskeletal proteins regulates Tau in Alzheimer's Disease, "Sticks with whips in neurodegenerative diseases: On the roles of intrinsic disorder in (dis)function of cytoskeletal proteins", Glial Fibrillary Protein is potential biomarker For AD, and much more.
Additional chapters cover Cytoskeletal disintegration in cardiovascular disease-related neurodegeneration, Cytoskeletal Proteins in Neurodegeneration, Extracellular matrix degradation proteins in Neurodegenerative disease, GPCRs regulates Cytoskeletal remodeling in microglia, Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer's Disease, Chemokine receptors modulates Cytoskeletal proteins in Alzheimer’s disease, Cytoskeletal Intermediate Filament proteins in Neurodegeneration, Mechanism of tau proteins differentially regulating the motility of different families of kinesin motors, The Quest to Restore Neuronal Structure: Targeting Cytoskeletal Proteins in Neurodegenerative Diseases, and many more timely topics.
Additional chapters cover Cytoskeletal disintegration in cardiovascular disease-related neurodegeneration, Cytoskeletal Proteins in Neurodegeneration, Extracellular matrix degradation proteins in Neurodegenerative disease, GPCRs regulates Cytoskeletal remodeling in microglia, Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer's Disease, Chemokine receptors modulates Cytoskeletal proteins in Alzheimer’s disease, Cytoskeletal Intermediate Filament proteins in Neurodegeneration, Mechanism of tau proteins differentially regulating the motility of different families of kinesin motors, The Quest to Restore Neuronal Structure: Targeting Cytoskeletal Proteins in Neurodegenerative Diseases, and many more timely topics.
Key features
Key features
- Provides a detailed exploration of cytoskeletal protein families (e.g., microtubules, neurofilaments, actin) and their roles in neuronal function
- Presents a discussion of protein aggregation, misfolding, post-translational modifications, and their impact on neuronal health
- Examines cytoskeletal proteins as potential biomarkers for early diagnosis and disease progression
Readership
Readership
Neuroscientists, Neurologists, Molecular biologists, Graduate students
Table of contents
Table of contents
1. Cytoskeletal proteins regulates Tau in Alzheimers Disease
Subashchandrabose Chinnathambi and Anusree Adithyan
2. "Sticks with whips in neurodegenerative diseases: On the roles of intrinsic disorder in (dis)function of cytoskeletal proteins"
Vladimir N. Uversky and Swayam Jyothi Tirupathi
3. Glial Fibrillary Protein is potential biomarker For AD
Subashchandrabose Chinnathambi, Gowshika Velmurugan and Madhura Chandrashekar
4. Cytoskeletal disintegration in cardiovascular disease-related neurodegeneration
Ufuk Çakatay, Erdem Atasever, Tamer Cebe, Şeydanur Turgut and Gülnur Andican
5. Cytoskeletal Proteins in Neurodegeneration
Amit Mishra, Rohan Dhiman, Amit Prasad, Rahul Kumar Verma, Subashchandrabose Chinnathambi, Sumit Kinger, Akash Choudhary, Prashant Kumar, Yuvraj Anandrao Jagtap and Vivek Sharma
6. Extracellular matrix degradation proteins in Neurodegenerative disease
Subashchandrabose Chinnathambi, Gowshika Velmurugan, Sneha Malik, Amit Mishra and Poornima Priyadarshini CG
7. GPCRs regulates Cytoskeletal remodeling in microglia
Subashchandrabose Chinnathambi, Nagaraj Rangappa, Gowshika Velmurugan and Madhura Chandrashekar
8. Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer's Disease
Poornima Priyadarshini and Basavaraju K C
9. Chemokine receptors modulates Cytoskeletal proteins in Alzheimer’s disease
Subashchandrabose Chinnathambi, Nagaraj Rangappa and Madhura Chandrashekar
10. Cytoskeletal Intermediate Filament proteins in Neurodegeneration
Subashchandrabose Chinnathambi and Sneha Malik
11. Mechanism of tau proteins differentially regulating the motility of different families of kinesin motors
Ping Xie
12. The Quest to Restore Neuronal Structure: Targeting Cytoskeletal Proteins in Neurodegenerative Diseases
Selvaraj Chandrabose Sr.
13. Pathological Microtubule Dynamics in Parkinson’s Disease: Mechanisms and Therapeutic Implications
Vijay Kumar Prajapati
14. Bioanalytical Approaches Applied to Identify Cytoskeletal Proteins Associated with Neurodegenerative Diseases
Cícero Alves Lopes Júnior
15. Tau-Cytoskeleton and their interaction with other neurodegenerative proteins
Subashchandrabose Chinnathambi, Nagaraj Rangappa, Monalisa Mishra and Surajita Sahu
16. How cargo driven by kinesin motors can pass efficiently through tau islands on microtubules
Ping Xie
Subashchandrabose Chinnathambi and Anusree Adithyan
2. "Sticks with whips in neurodegenerative diseases: On the roles of intrinsic disorder in (dis)function of cytoskeletal proteins"
Vladimir N. Uversky and Swayam Jyothi Tirupathi
3. Glial Fibrillary Protein is potential biomarker For AD
Subashchandrabose Chinnathambi, Gowshika Velmurugan and Madhura Chandrashekar
4. Cytoskeletal disintegration in cardiovascular disease-related neurodegeneration
Ufuk Çakatay, Erdem Atasever, Tamer Cebe, Şeydanur Turgut and Gülnur Andican
5. Cytoskeletal Proteins in Neurodegeneration
Amit Mishra, Rohan Dhiman, Amit Prasad, Rahul Kumar Verma, Subashchandrabose Chinnathambi, Sumit Kinger, Akash Choudhary, Prashant Kumar, Yuvraj Anandrao Jagtap and Vivek Sharma
6. Extracellular matrix degradation proteins in Neurodegenerative disease
Subashchandrabose Chinnathambi, Gowshika Velmurugan, Sneha Malik, Amit Mishra and Poornima Priyadarshini CG
7. GPCRs regulates Cytoskeletal remodeling in microglia
Subashchandrabose Chinnathambi, Nagaraj Rangappa, Gowshika Velmurugan and Madhura Chandrashekar
8. Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer's Disease
Poornima Priyadarshini and Basavaraju K C
9. Chemokine receptors modulates Cytoskeletal proteins in Alzheimer’s disease
Subashchandrabose Chinnathambi, Nagaraj Rangappa and Madhura Chandrashekar
10. Cytoskeletal Intermediate Filament proteins in Neurodegeneration
Subashchandrabose Chinnathambi and Sneha Malik
11. Mechanism of tau proteins differentially regulating the motility of different families of kinesin motors
Ping Xie
12. The Quest to Restore Neuronal Structure: Targeting Cytoskeletal Proteins in Neurodegenerative Diseases
Selvaraj Chandrabose Sr.
13. Pathological Microtubule Dynamics in Parkinson’s Disease: Mechanisms and Therapeutic Implications
Vijay Kumar Prajapati
14. Bioanalytical Approaches Applied to Identify Cytoskeletal Proteins Associated with Neurodegenerative Diseases
Cícero Alves Lopes Júnior
15. Tau-Cytoskeleton and their interaction with other neurodegenerative proteins
Subashchandrabose Chinnathambi, Nagaraj Rangappa, Monalisa Mishra and Surajita Sahu
16. How cargo driven by kinesin motors can pass efficiently through tau islands on microtubules
Ping Xie
Product details
Product details
- Edition: 1
- Latest edition
- Volume: 150
- Published: March 31, 2026
- Language: English
About the editors
About the editors
SC
Subashchandrabose Chinnathambi
Subashchandrabose Chinnathambi is Additional Professor at the Department of Neurochemistry, National Institute of Mental Health and Neurosciences Hospital Bangalore, Karnataka, India. His scientific interests include physiopathology of neurodegenerative disorders, Tau Cytoskeleton, Tau-GPCR, purinergic and chemokine receptors, Tau stem cells, animal models, neuropharmacology, therapeutic approaches targeting Tau oligomers, and biomarkers for neurodegeneration. He serves on the editorial board for various international cell biology journals and is also a regular invited speaker at a number of meetings and workshops. Dr. Chinnathambi has more than 16 years of research experience in the area of neuroscience and Tau-related research in Alzheimer’s Disease.
Affiliations and expertise
Additional Professor, Department of Neurochemistry, National Institute of Mental Health and Neurosciences Hospital Bangalore, Karnataka, IndiaRD
Rossen Donev
Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.
Affiliations and expertise
Head of Research, MicroPharm Limited, UKView book on ScienceDirect
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