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Books in Genetics

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    • Apolipoprotein E in Health and Disease

      Unravelling its Intricate Roles
      • 1st Edition
      • Dileep Kumar + 2 more
      • English
      Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles offers a thorough investigation into Apolipoprotein E (ApoE), emphasizing its importance across a spectrum of health conditions. This book details ApoE’s structure, genetic diversity, and functional significance, exploring how this protein impacts cardiovascular health, Alzheimer’s disease, neurological disorders, metabolic syndrome, and more. Through well-researched chapters, it highlights ApoE’s influence on lipid metabolism, heart disease, and the genetic factors contributing to Alzheimer’s, establishing the foundation for precision medicine and targeted therapeutic interventions. Beyond its primary focus, the book also examines ApoE’s broader effects on cognitive decline, liver function, cancer susceptibility, and immune responses.It delves into the pharmacogenetics of ApoE, addressing how genetic variations shape medication effectiveness and treatment plans. Innovative topics such as infectious disease management, genetic engineering, and advanced drug delivery systems are discussed, making this resource valuable for researchers, clinicians, and students alike.

    • Frontiers of Cancer Biology

      Current Trends in Cancer Research
      • 1st Edition
      • Devavarapu Kasi Viswa Prasad + 1 more
      • English
      Frontiers of Cancer Biology: Current Trends in Cancer Research presents the latest research in cancer, which is advancing day by day. This book provides an introduction to cancer genetics, as well as the roles of genomic instability, oncogenes, proto-oncogenes, tumor suppressor genes, and DNA damage and repair in relation to cancer. It then goes on to discuss viral genomics and cancer, epigenetics and cancer, cancer genetics, gene therapy in precision medicine. Finally, this book reviews the future direction of cancer genetics. Frontiers of Cancer Biology: Current Trends in Cancer Research is a valuable resource for researchers and professionals working in cancer biology, as well as academics that want to keep up to date with the field.

    • Nanomedicine and Nutrigenomics

      Pioneering the Future of Health
      • 1st Edition
      • Yugal Kishore Mohanta + 2 more
      • English
      Nanomedicine and Nutrigenomics: Pioneering the Future of Health offers a comprehensive introduction to nanomedicine and nutrigenomics, ensuring readers grasp the fundamental concepts, techniques, and applications. The book provides an overview of nanotechnology, nanomaterials, and gene-nutrient interactions, paving the way for understanding the potential healthcare applications of these groundbreaking methodologies. It emphasizes the synergy between nanomedicine and nutrigenomics, showcasing how they can optimize health outcomes and delving into nanotechnology's role in enhancing drug delivery systems, diagnostics, and therapeutics, while also highlighting personalized nutrition interventions based on genetic makeup. The book addresses future advancements, ethical implications, and challenges, presenting a holistic view.

    • DNA in Health, Identity, and Ancestry

      • 1st Edition
      • Hisham Atan Edinur + 2 more
      • English
      DNA in Health, Identity and Ancestry examines the human genome and advances in molecular techniques in relation to their value in health, genetic ancestry, and forensic DNA. This book systematically presents these three areas, providing new insights into recent developments in these fields, including gene editing, ancestral fraction determination, and DNA profiling. It covers the latest advances in molecular biology to understand the pertinent issues in these areas. DNA in Health, Identity and Ancestry provides an introduction to human genomes, and then delves into health, forensics and ancestry across 36 chapters. Each section is concluded with practical case studies to demonstrate the application of the principles discussed in each respective section. This book is a valuable resource for researchers, practitioners, and postgraduate students in biochemistry, molecular biology and genetics. It not only provides them with fundamental knowledge on genetics, diseases, population genetics and forensic DNA, but also presents advances, technical operational standards, analytical tools and recent developments in these respective areas.

    • Investigative and Predictive DNA Testing

      • 1st Edition
      • Hirak Ranjan Dash
      • English
      Investigative and Predictive DNA Testing delves into the cutting-edge of DNA analysis, presenting a comprehensive guide that unlocks the potential of DNA in solving complex cases. This book stands as a vital resource for students, practitioners, and researchers in fields such as biology, zoology, medicine, anthropology, microbiology, and genetics. Designed for those with a basic understanding of biological sciences, it is particularly beneficial for graduate, post-graduate, and research level students. The book explores the evolution of DNA analysis, focusing on predictive methods and investigative leads such as ancestry, lineage, and phenotype.Each chapter, contributed by internationally renowned experts, highlights the transformative role of artificial intelligence and machine learning in enhancing the accuracy and utility of DNA analysis. The book is comprised of various sections, starting with fundamental concepts of investigative and predictive DNA analysis, followed by technological advancements in the field, and concluding with the challenges and future concerns of DNA analysis. It serves as an indispensable tool for anyone looking to expand their knowledge and skills in DNA analysis, making it a must-read for the scientific community.

    • From DNA to Traditional Chinese Medicine

      • 1st Edition
      • Jesse Li-Ling
      • English
      From DNA to Traditional Chinese Medicine presents how genetic disorders can be explained using concepts of Traditional Chinese Medicine. This book explores the striking correlation between the characteristics of congenital syndromes and fundamental concepts of Traditional Chinese Medicine, such as Jing-Mai (Meridians or Channels) and Zang-Fu (the Yin and Yang internal organs). This correlation appears to be systematic and comprehensive, suggesting that these Chinese concepts have correctly summarized the connections between particular parts of the human body during embryonic development. Should this discovery be correct, it will have an immense impact on the understanding of genomic medicine as well as Chinese medicine. The uncovering of the mechanism of Chinese medicine, may also lead to development of new treatments for various human diseases. This book covers topics including genetic syndromes and fundamental concepts of Traditional Chinese Medicine. Starting with DiGeorge/Velocardiof... syndrome, this book will first introduce the basics of Medical Genetics and congenital syndromes, and then the fundamental concepts of Traditional Chinese Medicine including Jing-Mai and Zang-Fu. It will provide a completely new perspective on genetic syndromes with insights into how they relate to Traditional Chinese Medicine. This book is a valuable resource for graduates, medical undergraduates and researchers as well as professionals from both academia and industry.

    • Epigenetics Methods

      • 2nd Edition
      • Trygve O. Tollefsbol
      • English
      Epigenetics Methods, Second Edition offers an extensive overview of the tools that enhance translational epigenetics studies. This edition includes updated and revised chapters, along with newly added topics such as MALDI-TOF-MS for analyzing DNA methylation and the RIP assay for lncRNA binding. Specialists provide step-by-step guidance on methods used to study various epigenetic mechanisms. The book covers both fundamental and advanced techniques, making it an essential resource for researchers in this dynamic field. In addition to DNA methylation and histone modification techniques, the book also explores chromatin evaluation, enzyme analyses, and non-coding RNAs as epigenetic modulators.New chapters discuss recent advancements like single-cell epigenomics, epigenetic editing, and computational epigenetics. The volume addresses reproducibility issues and offers consensus-driven methods to unify approaches across experiments and labs. This edition is a vital reference for understanding and employing cutting-edge epigenetics methods.

    • Encyclopedia of Bioinformatics and Computational Biology

      • 2nd Edition
      • Shoba Ranganathan + 2 more
      • English
      Bioinformatics and Computational Biology (BCB) combine elements of computer science, information technology, mathematics, statistics, and biotechnology, providing the methodology and in silico solutions to mine biological data and processes, for knowledge discovery.In the era of molecular diagnostics, targeted drug design, translational medicine and Big Data for personalized medicine, computational methods for data analysis are essential tools for biochemistry, biology, biotechnology, pharmacology, biomedical and computer science, as well as mathematics and statistics. New areas are emerging, and relatively isolated fields are becoming current hot research areas in BCB, such as Artificial Intelligence, Quantitative Biology, Computational Vaccinology, Epidemiology and Infection Diffusion, Synthetic Biology, and Phenomics. The role of BCB in characterizing SARS-CoV-2 variants and facing the COVID-19 pandemic is just one example of how these tools can help us better prepare for such future events.This Encyclopedia comprises three sections, covering Methods, Topics, and Applications. The methodologies and algorithms underpinning BCB are described in the Methods section; Topics covers traditional areas such as phylogeny, as well as more recent areas such as translational bioinformatics, cheminformatics and environmental informatics; Applications provides guidance for commonly asked “how to” questions.Navigating the maze of confusing jargon and the plethora of software tools is often confronting for students and researchers alike. This comprehensive and unique resource provides up-to-date theory and application content to address molecular data analysis requirements, with precise definitions of terminology and lucid explanations by field experts.

    • Computational Genomics and Structural Bioinformatics in Microbial Science

      Microbial Genomics Volume 2
      • 1st Edition
      • Javid Ahmad Parray + 2 more
      • English
      Computational Genomics and Structural Bioinformatics in Microbial Science: Microbial Genomics (Volume 2) covers different aspects of microbial genomics, metagenomics, and functional studies of microbes through informative illustrations of current trends in computational tools and bioinformatics approach in environmental microbiology and clinical diagnosis. This book aims to provide readers with an overview of the microbial genome, computational genomics, and structural bioinformatics in microbial science, as well as the most recent developments in these fields. This book covers a range of topics, including the challenges and opportunities of computational epigenomics, bioinformatics tools for assessing metagenomic data, as well as computed comparative genomics and computational phenotyping of microorganisms relevant to agriculture. Microbial Genomics: Host Adaptation, virulence, and Evolution is a valuable resource for faculty members, researchers, and undergraduate and postgraduate students at universities, medical research labs, that are interested in microbial science specifically related to the microbial genome, computing genomics, and bioinformatics.

    • Host Adaptation, Virulence, and Evolution

      Microbial Genomics Volume 1
      • 1st Edition
      • Javid Ahmad Parray + 2 more
      • English
      Microbial Genomics: Host Adaptation, Virulence, and Evolution covers different aspects of microbial genomics, metagenomics, and functional studies of microbes that have provided a significant understanding of microbial-host interactions, virulence function, host adaptation mechanisms, including microbial evolution. Microbial Genomics: Host Adaptation, virulence, and Evolution is a comprehensive source on the latest updates and applications of microbial genomics information to understand the plant, microbe interaction, host adaptation, virulence nature of the infectious pathogen, microbial evolution, host-pathogen interactions contribute to shaping the genetic diversity of both organisms. Sections include an introduction to Microbial Genomics, followed by sections on Plant Microbiome, Genome Editing Prospecting and Approaches, Microbial virulanse and disease incidence. The final section of the book covers Microbial Genomics and evolutionary concepts. “Microbial Genomics: Host Adaptation, virulence, and Evolution” is a valuable resource for faculty members, researchers, and undergraduate and postgraduate students at universities, medical research labs, industries, and government agencies that are interested in the microbial science specific to the microbial genome, virulence function of pathogenic microbes, host adaptation, evolution of microbes, and all other disciplines related to molecular microbiology.