Apolipoprotein E in Health and Disease
Unravelling its Intricate Roles
- 1st Edition - April 3, 2026
- Latest edition
- Editors: Dileep Kumar, Ankit Ganeshpurkar, Aditya Ganeshpurkar
- Language: English
Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and di… Read more
Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease.
In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.
In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.
- Provides a comprehensive examination of Apolipoprotein E (ApoE) in various health conditions and diseases, including cardiovascular diseases, Alzheimer's, neurological disorders, and cancer
- Delivers detailed insights into the genetic variability of ApoE, explaining how different genotypes influence disease risk and therapeutic responses
- Integrates perspectives from biochemistry, molecular biology, genetics, neurology, and cardiology to offer a holistic understanding of ApoE
- Highlights the pharmacogenetics of ApoE, illustrating its potential in personalized medicine and targeted therapeutic strategies
Researchers and Scientists: Working in the fields of biochemistry, molecular biology, genetics, neurology, cardiology, and related disciplines. Clinicians and Healthcare Professionals: In fields related to cardiovascular health, neurology, Alzheimer's disease, and other medical specialties. Students and Academics: Pursuing undergraduate or graduate studies in the life sciences, pharmacology, or medicine. Pharmaceutical Industry Professionals: Involved in drug development and personalized medicine research. Public Health Practitioners: Interested in the role of genetics and lipid metabolism in disease susceptibility and prevention. Genetic Counselors: Working with patients or families with genetic disorders related to Apolipoprotein E, such as familial hypercholesterolemia. Neuroscientists and Neurologists: Investigating the links between Apolipoprotein E and neurodegenerative diseases, such as Alzheimer's and Parkinson's
1. Apolipoprotein E (ApoE): Structural Insights, Functionality, and Genetic Variability
2. Apolipoprotein E and Cardiovascular Pathophysiology: A Comprehensive Exploration
3. Apolipoprotein E in Alzheimer's Disease: Genetic Predisposition and Mechanistic Implications
4. Apolipoprotein E and Neurological Disorders: Beyond Alzheimer's Disease
5. Apolipoprotein E's Impact on Metabolic Syndrome: A Systematic Analysis
6. Apolipoprotein E and Liver Health: Implications in Lipid Metabolism and Disease
7. Apolipoprotein E and its Role in Cancer: Insights into Carcinogenic Associations
8. Apolipoprotein E's Immune Mediation: Implications in Inflammatory Disorders
9. Pharmacogenetics of Apolipoprotein E: Precision Medicine and Therapeutic Implications
10. Challenges and Prospects in Targeting ApoE for Disease Management
11. Apolipoprotein E and Infectious Diseases: A Framework for Therapeutic Developments
12. Genetic Engineering of Apolipoprotein E: Innovations and Clinical Applications
13. Apolipoprotein E and Precision Medicine: Individualized Disease Management Approaches
14. Apolipoprotein E in Drug Delivery Systems: Targeted Pharmacotherapeutics
15. Apolipoprotein E and Autoimmune Disorders: Therapeutic Frontiers
2. Apolipoprotein E and Cardiovascular Pathophysiology: A Comprehensive Exploration
3. Apolipoprotein E in Alzheimer's Disease: Genetic Predisposition and Mechanistic Implications
4. Apolipoprotein E and Neurological Disorders: Beyond Alzheimer's Disease
5. Apolipoprotein E's Impact on Metabolic Syndrome: A Systematic Analysis
6. Apolipoprotein E and Liver Health: Implications in Lipid Metabolism and Disease
7. Apolipoprotein E and its Role in Cancer: Insights into Carcinogenic Associations
8. Apolipoprotein E's Immune Mediation: Implications in Inflammatory Disorders
9. Pharmacogenetics of Apolipoprotein E: Precision Medicine and Therapeutic Implications
10. Challenges and Prospects in Targeting ApoE for Disease Management
11. Apolipoprotein E and Infectious Diseases: A Framework for Therapeutic Developments
12. Genetic Engineering of Apolipoprotein E: Innovations and Clinical Applications
13. Apolipoprotein E and Precision Medicine: Individualized Disease Management Approaches
14. Apolipoprotein E in Drug Delivery Systems: Targeted Pharmacotherapeutics
15. Apolipoprotein E and Autoimmune Disorders: Therapeutic Frontiers
- Edition: 1
- Latest edition
- Published: April 3, 2026
- Language: English
DK
Dileep Kumar
Dileep Kumar received his B. Pharm from Manipal College of Pharmaceutical Sciences, Manipal University, and M. Pharm from S.G.S.I.T.S Indore, Madhya Pradesh. He has several patents to his credit. He was awarded a Junior Research fellowship by National Medicinal Plant Board (NMPB) New Delhi, Senior Research Fellowship from University Grants Commission (UGC), Teaching Assistantship, and institute Post-Doctoral fellowship from IIT (BHU) Varanasi. At present, he is teaching as an assistant professor at Poona College of pharmacy, Bharti Vidyapeeth University Pune. He has published many papers and patents. He is Guest editor of several Prestigious journals. At present he is visiting professor in the department of entomology and Comprehensive Cancer Center in university of California Davis
Affiliations and expertise
University of California, Davis, USAAG
Ankit Ganeshpurkar
Dr. Ganeshpurkar's primary goal is to establish a distinct presence in the realm of medicinal chemistry and drug design research, with a specific focus on harnessing computational tools and artificial intelligence to advance the processes of lead discovery and optimization. His research is centred around in silico drug design, lead identification, and optimization. Additionally, his work encompasses the design, synthesis, and thorough biological assessment of novel leads tailored to address diverse pathophysiological conditions, including but not limited to Alzheimer's disease and various neurodegenerative disorders.
Affiliations and expertise
Bharati Vidyapeeth (Deemed to be University), IndiaAG
Aditya Ganeshpurkar
Dr. Aditya Ganeshpurkar holds a Ph.D. in pharmacology and has extensive experience in both academics and research. His research primarily focuses on pharmacological and nutraceutical studies, with an emphasis on drug discovery, evaluation, and immunomodulation. Dr. Ganeshpurkar has published numerous research articles, review articles, and book chapters in various scientific journals and has presented his work at national seminars and conferences. His research areas include the evaluation of herbal and synthetic drugs, immunomodulatory potential, and the development of drug delivery systems. He has more than 3000 citations with h index of 28 and holds a place in top 2% of scientist in the pharmacy field.
Affiliations and expertise
Shri Ram Institute of Technology-Pharmacy, India