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Elsevier

Books in Physiology

Covering the functions of organ systems, neurobiology, and integrative physiology, this portfolio supports clinicians, researchers, and students. It features cutting-edge research, experimental methods, and clinical applications that enhance understanding of health, disease, and human performance.

  • Practice-Based Physiology in Allied Health Sciences

    From Evidence to Clinical Application
    • 1st Edition
    • Satyajit Tripathy + 3 more
    • English
    Practice-Based Physiology in Allied Health Sciences: From Evidence to Clinical Application provides a comprehensive, systems-based exploration of human physiology specifically designed for applied health sciences. It moves beyond conventional textbook knowledge to integrate cardiovascular, respiratory, neurological, endocrine, and musculoskeletal systems within the context of real-world clinical and functional applications. By emphasizing translational physiology, the text helps readers understand how cellular and systemic mechanisms directly inform therapeutic assessment, intervention planning, and patient-centered care. The book’s multidisciplinary perspective supports students and practitioners in physiotherapy, occupational therapy, nursing, sports medicine, and behavioral science—highlighting physiology as a common language that unites diverse healthcare disciplines. Through detailed explanations, case studies, and applied scenarios, readers learn to interpret physiological data, identify dysfunctions, and design interventions grounded in scientific evidence. Ultimately, this resource bridges the gap between science and practice by linking physiological understanding to outcomes such as recovery, mobility, pain management, fatigue reduction, and overall well-being. It encourages critical thinking, clinical reasoning, and interprofessional collaboration—ensuri... that learners not only grasp how the human body functions but also how that knowledge can meaningfully improve health, performance, and quality of life.

  • Evolutionary Adaptations and Mosquito-Borne Viruses

    • 1st Edition
    • Volume 70
    • English
    Evolutionary Adaptations and Mosquito-Borne Viruses comprises comprehensive reviews of various topics in mosquito adaptations and mosquito-virus interactions, with insights into future research prospects. The topics covered in this volume include mechanisms of insecticide resistance, thermal and desiccation tolerance, insect-specific viruses and their interactions with pathogenic viruses, mosquito viral immunity, factors affecting vector competence, host preference, saliva and viral pathogenesis, microbiota and symbionts, gene drives and genetic modification of mosquitoes, and microRNA roles in mosquito-virus interactions.

  • Engelking's Textbook of Veterinary Physiological Chemistry

    • 4th Edition
    • Kevin Connolly
    • English
    Bridging the gap between basic and clinical science concepts, Engelking's Textbook of Veterinary Physiological Chemistry, Fourth Edition offers broad coverage of biochemical principles for students and practitioners of veterinary medicine. The only recent biochemistry book written specifically for the veterinary field, this updated text covers cellular-level concepts related to whole-body physiologic processes in a reader-friendly, approachable manner. Each chapter is written in a succinct and concise style that includes an overview summary section, numerous illustrations for best comprehension of the subject matter, targeted learning objectives, and end of the chapter study questions to assess understanding.With numerous illustrations and both instructor and student companion websites with updated PowerPoint images, lecture slides, and Snapcasts, Engelking's Textbook of Veterinary Physiological Chemistry, Fourth Edition, proves useful to students and lecturers from diverse educational backgrounds. Sectional exams and updated case studies extend the breadth and depth of learning resources.

  • Procedural Medicine for Spaceflight

    • 1st Edition
    • Dana Levin + 2 more
    • English
    Procedural Medicine for Spaceflight is a collection of research and experiential data on procedural medicine and the needs of those involved in Space Medicine. Procedural medicine is a core competency for the specialty of Space Medicine, but there is no single reference available which addresses the unique spaceflight environment or the medical techniques required to ensure success.This book is divided into six sections. Starting with the Introduction, then moving to Procedural Considerations, Anesthesia and Pain Management; Post Procedure Care; Other Considerations; and concluding with The Future of Procedural Medicine in Space. Each chapter is written by experienced subject matter experts in relevant disciplines. This book is intended for physicians, medical students, engineers, mission planners, and medical researchers interested in and/or training in Space Medicine.

  • Mucosal Barriers and Host-Microbiota Interplay

    Dysbiosis to Barrier Dysfunction
    • 1st Edition
    • Linda Chia-Hui Yu
    • English
    Mucosal Barriers and Host-Microbiota Interplay: Dysbiosis to Barrier Dysfunction, a volume in Elsevier's new series Hot Topics in Physiology, provides an in-depth exploration of mucosal barriers, including their structure, establishment, and consideration of different diseases and intervention strategies. Published in association with the International Union of Physiological Sciences (IUSP), this is an ideal reference for those researching or studying biology and medicine, particularly gastroenterology. Biotechnological companies working on metagenomics sequencing and analysis may also find this volume useful.As a massive load of commensal microbes, consisting of bacteria, viruses, and fungi resides in the gastrointestinal tract and other mucosal surfaces, collectively termed microbiota, this book provides an update on new and existing knowledge. Mucosal barriers, including the epithelial layers and immune cells act as the frontline to strategically confine these microorganisms and prevent the entry of microbes into the body proper.

  • Encyclopedia of Cardiovascular Research and Medicine

    • 2nd Edition
    • Vasan Ramachandran S. + 1 more
    • English
    Now in its second edition, the Encyclopedia of Cardiovascular Research and Medicine is a four‑volume print and online reference that brings together the essential knowledge needed to understand the heart and vascular system. Designed for students, clinicians, researchers, and instructors, it offers clear, authoritative coverage of how the cardiovascular system develops, functions, becomes injured, and can be repaired. Because cardiovascular disease remains the world’s leading cause of death, this edition provides the up‑to‑date scientific and clinical insights needed to support research, inform care, and improve outcomes.This revised edition includes around 180 expert articles spanning cardiac development and regeneration, vascular biology, genetics and omics technologies, coronary and acute cardiac syndromes, heart failure, electrophysiology and device therapies, imaging, population health, and modern research methods. By spanning basic, clinical, and population sciences, the encyclopedia supports a wide range of users from those seeking introductory knowledge to specialists pursuing advanced expertise in cardiovascular medicine.

  • Seldin and Giebisch's The Kidney

    Physiology and Pathophysiology
    • 6th Edition
    • Robert J. Alpern + 3 more
    • English
    Seldin and Giebisch’s The Kidney: Physiology and Pathophysiology, Sixth Edition provides a common language for nephrology researchers, fellows, and practicing nephrologists to discuss normal and abnormal renal physiology and the development and diagnosis of a wide range of renal diseases. Guided by a team of four distinguished authorities in nephrology, experts from all areas of renal research and practice take readers from the structure and function of the normal kidney, to the specific cellular and molecular mechanisms underlying disease development, and into the management of renal disease through physiologic regulation. This classic nephrology reference for nearly 30 years combines basic and clinical sciences that provides authoritative, concise, and readily accessible information. Academic, medical, and pharma researchers save valuable time by quickly accessing the very latest details on renal physiology and pathophysiology as opposed to searching through thousands of journal articles.

  • Comparative Fish Immunology

    • 1st Edition
    • Volume 42
    • English
    Comparative Fish Immunology, Volume 42 in the Fish Physiology series, presents chapters written by leading experts. Covering a broad range of topics, this edition explores the evolution and function of immune systems in fish, with particular attention to both innate and adaptive immune mechanisms across diverse aquatic species. Chapters examine adaptive immunity in jawless vertebrates and the unique VLR system, the role of antimicrobial peptides in teleost infections, and the use of zebrafish as a model for studying innate immune responses. Additional contributions explore pharyngeal mucosal lymphoid structures, the evolutionary origins of germinal centers in fish, and mechanisms of antigen presentation in teleosts.Other chapters address microbiota–host immune interactions, emerging insights into teleost neuroimmunology, and the modulation of immune function through behavioral fever. Together, these contributions provide a comprehensive overview of current discoveries and evolving perspectives in fish immunology, offering valuable insights for researchers, immunologists, and aquatic biologists interested in the physiology and immune biology of fishes.

  • The Cardiac Conduction System

    Evolution, Development, and Therapeutic Potential
    • 1st Edition
    • Bjarke Jensen + 1 more
    • English
    The Cardiac Conduction System: Evolution, Development, and Therapeutic Potential, the latest release in the Hot Topics in Physiology series, provides the reader a thorough and comprehensive review of this intricate system. The book covers conventional topics: anatomy, electrophysiology, and key cellular characteristics, as well as emerging topics: patient specific computer modelling, induced pluripotent stem cells, and in vivo editing as state-of-the-art treatment strategy. Given the exhaustive coverage of topics, this book is "go-to reference" for the cardiac conduction system for years to come.This volume was published in association with the International Union of Physiological Sciences (IUPS). It is an ideal reference for academics and researchers in anatomy, physiology, cardiology, electrophysiology, biomedical engineering and medical education at Undergrad, Masters, PhD, and Post-Doc levels.

  • Biomechanics of the Human Spine

    Basic Concepts, Spinal Disorders and Treatments
    • 2nd Edition
    • Fabio Galbusera + 1 more
    • English
    Biomechanics of the Human Spine: Basic Concepts, Spinal Disorders and Treatments, Second Edition is an essential resource for both biomedical engineers and spinal surgeons. The book is divided into four key sections, each building on the previous to offer a thorough understanding of spine biomechanics. It starts with the functional anatomy of the spine, emphasizing often overlooked aspects of clinical literature. The second section details the mechanics of spinal tissues, including testing setups and mathematical models. The third section explores contemporary spine research methods, while the final section addresses biomechanical aspects of spinal pathologies and their surgical treatments.Contribut... from leading institutions worldwide ensure the inclusion of the latest research and expertise in spine biomechanics. Highlights include in-depth experimental testing, numerical simulation, and in vivo studies, such as imaging and motion analysis. The book stands out for its comprehensive approach, bridging the gap between biomechanical knowledge and clinical application. It is indispensable for professionals in the field, offering valuable insights and practical guidance for understanding and treating spinal disorders.

  • Cell Physiology Sourcebook

    • 5th Edition
    • F. Javier Alvarez-Leefmans + 1 more
    • English
    Written by leading experts in the field, the fifth edition of the Cell Physiology Sourcebook, Fifth Edition offers a critical, comprehensive, and multidisciplinary overview of essential aspects of cell physiology and biophysics, spanning from bacterial and archaeal cells to mammalian cells and tissues. The present edition incorporates new molecular insights without losing the integrative perspective of cell physiology and biophysics, as well as its foundational concepts. Our target readers are advanced students and researchers interested in understanding how cells work.The history of this book goes back to Hugh Davson’s classic A Textbook of General Physiology, which reached its fourth and last edition in 1970. The successor of this influential work was Cell Physiology Sourcebook, first published in 1995 and edited by the late Professor Nicholas Sperelakis, with a foreword written by Davson. At that time, the knowledge of molecular and cell physiology became so vast that a single author's work, like its predecessor, was materially impossible. Professor Sperelakis, for whom we dedicate the present edition, put together an impressive volume with the contribution of various experts in fundamental areas of the field until the 4th edition, published in 2012, one year before his death. This book's success and the gap it fills motivated the present editors to continue this project, updating the entire book to reflect new developments.

  • Integrative Fish Biomechanics

    • 1st Edition
    • Volume 41
    • English
    Integrative Fish Biomechanics, Volume 41, the latest release in the Fish Physiology series, highlights new advances in the field, with this volume presenting insightful chapters written by leading experts. Covering a wide range of topics, this edition explores the intricate hydrodynamics and biomechanics of fish feeding, swimming, and terrestrial locomotion. It delves into the structural and functional properties of fish tissues, providing a deeper understanding of their mechanical adaptations.Other chapters examine the sensing and control of fish behaviour, the role of biomechanics in fish adhesion, and the emerging field of fish robotics. The volume also discusses the ecomechanics of fish locomotion and feeding, collective behaviours, and the micro- and macroevolutionary perspectives of fish biomechanics. Offering a comprehensive look at the intersection of biology, physics, and engineering, this book provides valuable insights for researchers, marine biologists, and those interested in fish physiology and biomechanics.

  • Quantitative Human Physiology

    An Introduction
    • 3rd Edition
    • Joseph J Feher
    • English
    Quantitative Human Physiology: An Introduction, Third Edition, winner of a 2018 Textbook Excellence Award (Texty), is the first text to meet the needs of the undergraduate bioengineering student who is being exposed to physiology for the first time but requires a more analytical/quantitat... approach. This book explores how component behavior produces system behavior in physiological systems. Through text explanation, figures, and equations, it provides the engineering student with a basic understanding of physiological principles, with an emphasis on quantitative aspects. The third edition has been revised with more and expanded problem sets and improved illustrations.

  • The Human Body

    Linking Structure and Function
    • 2nd Edition
    • Bruce M. Carlson
    • English
    The Human Body: Linking Structure and Function, Second Edition offers a comprehensive and accessible exploration of the human anatomy, making it an invaluable resource for students and professionals alike. Each chapter delves into a specific organ system, elaborating on how the unique structures within the body contribute to its overall functionality.Organi... by organ system, this succinct publication presents the functional relevance of developmental studies and integrates anatomical function with structure. A new chapter presents the functional anatomy of a joint, including the skeleton, muscles, connective tissues, nerves and vessels.Written by a leader in the field for upper undergraduate, graduate and postdoc market, as well as professors and researchers studying functional anatomy, developmental biology, physiology and across the life sciences, dentistry, and nursing.

  • Pharmacology, Physiology, and Practice in Obstetric Anesthesia

    • 1st Edition
    • Alan D. Kaye + 1 more
    • English
    Pharmacology, Physiology, and Practice in Obstetric Anesthesia provides all the essentials of obstetric anesthesia in a straightforward, user-friendly format that avoids encyclopedic language and lengthy discussions, and is inclusive of other healthcare specialties and subspecialties including obstetrics, neonatal care, and more. Coverage spans the essentials of obstetrics as well as overlooked issues including obstetric pharmacology and physiology safe practice strategies, clinical concepts for vaginal delivery and C-section, high-risk pregnancy states and management of the complicated parturient, complications and medicolegal, fetus and newborn considerations, and guidelines, standards and statements related to obstetric anesthesia.Pharmacol... Physiology, and Practice in Obstetric Anesthesia is the perfect reference for an interdisciplinary group of health professionals, policymakers, and researchers working and training in the field of obstetric anesthesiology

  • Precision Medicine for Long and Safe Permanence of Humans in Space

    • 1st Edition
    • Chayakrit Krittanawong
    • English
    Precision Medicine for Long and Safe Permanence of Humans in Space serves as a reference to assist with the diagnosis of medical conditions (e.g., microgravity, space radiation), monitoring inflight, clinical decision-making inflight, disease prediction and prevention (pre- or postflight), and the facilitation of precision space medicine. This book defines the basic concepts of space health, fundamental physics, and biology in space and highlights the current applications, current challenges, and future directions in space medicine. Each chapter discusses precision medicine to a specific medical subspecialty, including cardiovascular disease, neurology, nephrology, endocrinology, ophthalmology, hepatology, hematology, pulmonology, emergency medicine, nutrition, dermatology, immunology, mental health, regenerative medicine, surgery, vascular surgery, anesthesiology, urology, OB-GYN, and male and female reproductive issues in space. Additionally, this book discusses current artificial intelligence (AI) technology in space, AI in commercial space industry, and recent space health progress worldwide (e.g., NASA, China, Japan, the Middle East). This book serves as an ideal companion for healthcare professionals, scientists, researchers, postdoctoral fellows, students, or anyone interested in space travel.

  • Sex and Gender Differences in Cardiovascular-Renal-Metabolic Physiology and Pathophysiology

    Sex, Gender and Function
    • 1st Edition
    • Jane Reckelhoff + 2 more
    • English
    Sex and Gender Differences in Cardiovascular-Renal... Physiology and Pathophysiology: Sex, Gender and Function, the latest release in the Fundamentals of Physiology series, provides a fundamental overview on sex and gender differences in all aspects of physiology. The book shares information on sex and gender differences in a variety of topics in a single comprehensive volume. This book, published in association with the International Union of Physiological Sciences acts as a primer of information scientists can build upon with their own research in sex and gender-based research.

  • On Oxygen

    From Air to Tissues
    • 1st Edition
    • Michael Joyner + 1 more
    • English
    On Oxygen: From Air to Tissues, the latest release in the Fundamentals of Physiology series, provides a fundamental overview of the entire oxygen pathway, sharing key mechanistic insights into the alternating conductive and diffusive steps of O2 transport. The book describes specific aspects along each stage of the oxygen route through the body, from the transfer of air to the alveoli, through the lungs, to the ultimate fate of O2 in the mitochondria. Additionally, the effect of specific disease states, aging, and developmental aspects are considered.This book, published in association with the International Union of Physiological Sciences, acts is a valuable introduction to the full biological journey of oxygen, and is a beneficial guide for students and researchers in physiology, sport science, pulmonology, and related fields.

  • Truth Unveiled

    Navigating Science and Society in an Era of Doubt
    • 1st Edition
    • Faadiel Essop
    • English
    Faculty, students, researchers, and clinicians are struggling how to deal with the post-truth world as the broader public lacks an understanding of the complexity of the scientific research process. This has resulted in the dissemination of mis- and disinformation that is increasingly used to shape public opinion in medical-related matters, for example, the rise of anti-vaxxers and resistance to COVID-19 pandemic social isolation protocols. In addition, physiologists and scientists play relatively limited role when engaging the broader public in this regard. Truth Unveiled: Navigating Science and Society in an Era of Doubt provides valuable information to inform researchers and clinicians and better train students on the broader aspects of the scientific process and how to best counteract mis- and disinformation. This book is published as part of the Fundamentals of Physiology series in association with the International Union of Physiological Sciences and should be a useful resource for lecturers when training physiologists, biomedical scientists, and medical and allied health students.

  • Balancing a Sauropod

    The Physiology of a Dinosaur
    • 1st Edition
    • Brant E Isakson
    • English
    One completely unexplored area in terms of physiology is the era of dinosaurs—with good reason, they lived over 100 million years ago and we’re left to make inference based on fossilized bones. However, by merging classical, comparative, and extreme physiology and applying it to current paleontological knowledge of dinosaurs, Balancing a Sauropod: The Physiology of a Dinosaur will for the first time begin to provide a sound physiological underpinning for how they may have lived 100 million years ago. Sauropods were the largest land animals to ever walk the earth with an incredible distance from heart to brain, begging the question, how did they maintain blood flow in their brain? Also, the climate sauropods lived in was hypoxic compared to what we live in now, so how did the dinosaurs breathe in the hypoxic Jurassic era? These questions and others expand to multiple fascinating questions the book will dissect in order of organ systems. The topics focus on major organ systems and apply them to potential sauropod physiology. Less emphasis is given to the skeletal system, as that has been discussed extensively in other literature. Each organ system will be discussed in terms of function and current understanding of how they work in a comparative environment. Balancing a Sauropod: The Physiology of a Dinosaur is written at a technical level to both inform the lay reader and provide a sound argument to scientists in the field.

  • The 50th Anniversary Issue of Fish Physiology

    Physiological Applications
    • 1st Edition
    • Volume 40B
    • English
    Fish Physiology, Volume 40B recently celebrated its 50th Anniversary. The editors of the series have produced a total of 47 books (several volumes have two books) that contain almost 500 chapters since the inaugural volume published in 1969. Initial volumes were devoted to understanding the basic mechanisms and principles of fish physiology, with a focus on a few model species and some application to natural environmental conditions. Then, as the field better understood mechanisms, the approach was broadened to not only delve deeper into system physiology (e.g., chapters in early volumes were expanded to become books), but also interspecific differences in physiology.Finally, as interspecific physiological mechanisms were further resolved, it became possible to discuss physiology in light of a changing world. Thus, physiology can now inform on conservation, sustainability and management, as exemplified with the most recent volumes. This anniversary issue celebrates the series by highlighting some of the very important early work in the field that was published in the series.

  • Unveiling the History of Transplantation

    An Illustrated Review of the Boundaries, Fantasies and Realities
    • 1st Edition
    • Shi Chen
    • English
    Unveiling the History of Transplantation: An Illustrated Review of the Boundaries, Fantasies and Realities covers the key international figures involved in organ transplantation and related fields. It includes a discussion of the contributions of many Nobel Prize winners in Physiology and Medicine. The book introduces the whole process of transplantation and the latest research progress of cell, tissue, and organ transplantation: from initial exploration to maturity and on to widespread application. A key feature of this resource is that it includes a large number of unique historical photos and material related to organ transplantation as collected by the author from libraries worldwide.

  • Joint Replacement in the Human Body

    • 1st Edition
    • Thomas J Joyce
    • English
    Joint Replacement in the Human Body provides a comprehensive exploration of artificial joint designs. The book's primary focus is to introduce readers to the diverse landscape of artificial joint technologies while offering insights into their historical development. This book is divided into three sections, each addressing specific aspects of joint replacements. The first section delves into artificial joints of the lower limb, including the hip, knee, and ankle. In the subsequent section, the book explores upper limb replacements, covering joints such as the shoulder, elbow, wrist, finger, and thumb.The third section tackles broader themes like biotribology, regulatory aspects of joint replacements, examines noteworthy case studies like metal-on-metal hips, and addresses joint replacements not easily categorized in the previous sections, such as spinal total disc replacements. This book offers a critical assessment of the diverse and evolving design concepts currently in use, ranging from established metal-on-polymer joints to innovative biomimetic solutions. This book is designed to swiftly equip readers with a deep understanding of contemporary joint replacements and the immediate and long-term challenges they present.

  • Primate Anatomy

    Introduction to Extant Primates
    • 4th Edition
    • Friderun Ankel-Simons
    • English
    Primate Anatomy: Introduction to Extant Primates synthesizes the taxonomy, anatomy, physiology, and genomics of extant primates, including humans. It takes a holistic approach to describing primate skeletal, muscular, and organ structure and function, providing the tools to understanding the fundamentals and state of the science of primatology. Now in its fourth edition, this work introduces its audience to the history and objectives of the field of primatology. It enumerates and profiles extant primates before delving into detailed descriptions of primate skulls, brains, teeth, skeletons, musculature, organs, blood groups, reproduction, and development.In addition, the book highlights recent advances in primate genomics, including new genera and species assignments, and concludes with a glance at the future of the field. Written by longtime expert Friderun Ankel-Simons, this new edition effectively introduces complex biological concepts in a manner accessible to all readers. It will serve as an excellent reference for technical and non-technical audiences, including primatologists, anatomists, paleontologists, anthropologists, conservationists, and naturalists.

  • Encyclopedia of Fish Physiology

    • 2nd Edition
    • Sarah L. Alderman + 1 more
    • English
    Encyclopedia of Fish Physiology, Second Edition is a comprehensive, introductory-level reference work that aims to unite readers in the wonders of this discipline. Chapters highlight where physiological systems and processes are conserved across vertebrate groups, which supports the use of fish as a vertebrate model for investigating fundamental problems in physiology and knowledge transfer to the medical field. Other chapters highlight unique specializations and adaptations that allow fish to survive in challenging environments, leading to a deeper appreciation of the natural world. Final sections demonstrate the consequences of perturbing physiological systems and how this knowledge can empower conservation strategies to protect fish. Much has changed in the field of fish physiology since publication of the previous, Prose award winning, edition. For example, we understand better the impacts of global climate change on the physiological systems of fish, and we have gained a deeper mechanistic understanding of physiological processes through technological advancements such as gene editing with CRISPR, whole genome sequencing, and quantitative ‘omic` approaches. The new edition greatly expands the closing thematic section focused on applying fish physiology to real world challenges with topics including ocean acidification, declining habitat quality due to human activities, and the use of zebrafish in biomedical studies on tissue regeneration, neurological disorders and cancer.

  • Early Vascular Aging (EVA)

    New Directions in Cardiovascular Protection
    • 2nd Edition
    • Pedro Guimarães Cunha + 4 more
    • English
    Early Vascular Aging (EVA): New Directions in Cardiovascular Protection, Second Edition continues to be the most comprehensive and authoritative resource on premature alterations in artery structure and function. The book presents a novel approach to the problem of cardiovascular disease, showing it in relation to great vessels disease and revealing a comprehensive approach to the problem of increased rigidity of the great vessels, its causes, and further consequences. This second edition contains completely updated content with expanded coverage of basic and translational research, systematic reviews of the most prominent literature, discussion of applicability of new evidence and more. Written by an international team of clinicians and researchers, this is a valuable resource to basic and translational scientists, clinical researchers and clinicians in the cardiovascular field interested in prevention, diagnosis and treatment of EVA.

  • Diagnostic Molecular Pathology

    A Guide to Applied Molecular Testing
    • 2nd Edition
    • William B. Coleman + 1 more
    • English
    Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease.

  • Principles of Gender-Specific Medicine

    Sex and Gender-Specific Biology in the Postgenomic Era
    • 4th Edition
    • Marianne Legato J
    • English
    Awarded with the 2018 Prose Award in Clinical Medicine, the third edition of Principles of Gender-Specific Medicine explored and described exciting new areas in biomedicine that integrated technology into the treatment of disease and the augmentation of human function. Novel topics such as the sex-specific aspects of space medicine, the development and the use of genderized robots and a discussion of cyborgs were included in the third edition, providing a preview of the expanding world of sex-specific physiology and therapeutics. This Fourth Edition is a continuation of the mission to trace the relevance of biological sex to normal function and to the experience of disease in humans.We are now twenty years into the postgenomic era. The investigation of how the genome produces the phenome has led to fascinating insights as well as yet unanswered questions. Principles of Gender-Specific Medicine, Fourth Edition, has a central theme: discuss advances in understanding the role of epigenetics in regulating gene expression in a dynamic, sex-specific way during human life. It explores the protean role of epigenetics in human physiology, the relevance of environmental experience to human function, the therapeutic promise of cutting-edge methodologies like gene manipulation, the preparation of humans for space travel, the use of artificial intelligence in detection and therapeutic decisions concerning disease states, the possibilities for technological support of not only compromised individuals but of the augmentation of human function, and an analysis of the benefits, limitations and issues that surround our current expectations of personalized medicine.

  • Venous Ulcers

    • 2nd Edition
    • Cynthia K. Shortell + 1 more
    • English
    Venous Ulcers, Second Edition, provides a comprehensive synthesis of evidence-based recommendations and the highest level of expertise from a leading group of doctors, which is a fundamental constituent for the appropriate management of nonhealing venous wounds in everyday practice. This book offers a fertile environment for a complete understanding of genetics and molecular and biochemical mechanisms that lead to the development and progression of venous ulcers, which is essential for elucidating the underlying pathophysiology and can be utilized for developing novel therapies and accessing previously inaccessible areas of research. Socioeconomic impact, impact on health-related quality of life, the clinical course of the disease, and diagnostic algorithms are elaborated in detail. All currently available treatment modalities are explained in a clinically applicable approach with particular emphasis on operative technique, technical feasibility, success rates (both clinical and technical), and side effects. Lastly, this book elaborates on special diagnostic considerations and management of the most complex patients, often requiring the highest level of expertise for successful treatment.

  • Systems and Signal Processing of Capnography as a Diagnostic Tool for Asthma Assessment

    • 1st Edition
    • M. B. Malarvili + 4 more
    • English
    Systems and Signal Processing of Capnography as a Diagnostic Tool for Asthma Assessment provides a comprehensive overview of groundbreaking tools and techniques for the diagnosis and monitoring of asthma. Sections cover an introduction to the human respiratory system and the pathophysiology of asthma before analyzing current assessment concepts, tools and techniques. The book describes spirometry and the peak flow meter as existing tools in assessing asthma along with their limitations. In addition, a detailed description of capnography as a new approach is included with various studies conducted on its analysis. Academicians and researchers in biomedical engineering, particularly in the course of biomedical signal processing and biomedical instrumentation will find the book useful.

  • Aging

    From Fundamental Biology to Societal Impact
    • 1st Edition
    • Paulo J. Oliveira + 1 more
    • English
    Aging: From Fundamental Biology to Societal Impact examines the interconnection of the cellular and molecular basis of aging and societal-based challenges and innovative interventions. Sections take a societal-based angle on aging, describing several flagship initiatives for healthy living and active aging in different regions, cover the biology of aging which includes the hallmarks of aging, explain the pathophysiology of aging, describing different comorbidities associated with aging and possible interventions to decrease the impact of aging, and envision future and innovative measures to tackle aging-related morbidities.Contribu... from an interdisciplinary panel of experts cover such topics as the biology of aging to physical activity, nutrition, psychology, pharmacology, health care, social care and urban planning.

  • Beauty, Aging and AntiAging

    • 1st Edition
    • Ibrahim Vargel + 1 more
    • English
    Beauty, Aging and AntiAging covers novel and updated research and treatment options regarding the effects of aging on human physiology. Beauty perception and related molecular pathways are reviewed, along with current medical and surgical approaches to aging. The first part of the book focuses on beauty, youth, aging and its effects on the human body. In the second part, various restorative treatment approaches are reviewed in detail. Particularly, invasive treatment options and molecular pathophysiology of aging are covered in this book.

  • Exercise to Prevent and Manage Chronic Disease Across the Lifespan

    • 1st Edition
    • Jack Feehan + 2 more
    • English
    Exercise to Prevent and Manage Chronic Disease Across the Lifespan provides evidence-based insights into the clinical utility of exercise in the management of disease across a broad range of specialties and diseases. The book offers research informed strategies for the integration of exercise into standard practice in fields such as neurology, endocrinology, psychiatry and oncology, as well as decision-making pathways and clinical scenarios to advance patient care. The book is divided by specialty and includes clinical scenarios to allow for the integration of information within practice. The book's synthesized research evidence allows practitioners to safely and effectively begin to capitalize on the benefits of exercise in their patients.

  • Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease

    • 1st Edition
    • Julio A. Chirinos
    • English
    Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease, Two Volume Set covers the principles, physiology, biologic pathways, clinical implications and therapeutics surrounding arterial stiffness and pulsatile hemodynamics, along with a thorough overview of the field. The book presents complex engineering concepts in a way that those in science and medicine can more easily understand. It includes detailed illustrations. Additionally, it presents advanced bioengineering concepts in boxes for readers who wants more in-depth biophysical knowledge. This is a must-have reference for students, researchers and clinicians interested in learning more about this field.

  • Cardiovascular Pathology

    • 5th Edition
    • L. Maximilian Buja + 1 more
    • English
    Cardiovascular Pathology, Fifth Edition provides a comprehensive treatise on the pathology of cardiovascular diseases, combining presentations of detailed pathology of cardiovascular diseases coupled with contemporary insights into etiology and pathogenesis. Twenty-two chapters cover general topics, including cardiovascular genetics, heart failure, and transplantation, and specific congenital and acquired cardiovascular diseases, therapeutic interventions, and forensic aspects. New chapters address the scope of practice and training in cardiovascular pathology, with a focus on major diagnostic approaches used in contemporary practice and research in cardiovascular pathology, and a perspective on the field of cardiovascular regenerative medicine linked to the basic pathobiology of cell-based therapy. The book provides a unique combination of details of pathological anatomy essential for pathologists involved in the evaluation of cardiovascular specimens and cardiovascular diseases, and is an excellent reference for anyone interested in the natural history and therapeutic advances in the cardiovascular field.

  • Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies

    • 1st Edition
    • Tetsuya Watanabe
    • English
    Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies covers the neuronal cell communication system in excitable cells, recognizing the most relevant mechanisms of cell communication. Along with new findings in biotechnology, medicine and pathological cases for clinicians, the book highlights electrochemical potential in living nerve and muscle cells. Written for physiological scientists, pharmaceutical scientists, medical doctors, biologists and physicists, this book an essential read for a real understanding of the signals as we see them.

  • Muscle Biology

    The Life History of a Muscle
    • 1st Edition
    • Bruce M. Carlson
    • English
    Muscle Biology: The Life History of a Muscle looks at the story of a muscle from its embryonic beginnings, through its growth and ability to adapt to changing functional circumstances during adult life, to its eventual decline in both structure and function as old age progresses. Injury occurs to muscle during normal activity, after trauma, and during the source of certain diseases. Chapters on both muscle regeneration and muscle diseases emphasize the possibilities and limitsations of the healing capacity of muscle fibers. Muscle Biology begins with a brief review about the structure and function of a normal mature muscle and then proceeds to follow the developmental history of a muscle from the embryo to old age in a manner that gives the reader a perspective about not only developmental controls but also how at any stage of development a muscle is able to adapt to its functional environment. The book discusses both normal and abnormal changes in the muscle, the mechanisms behind those changes and how to mitigate deleterious changes from disease, 'normal' aging, and disuse/lack of physical activity. This is a must-have reference for students, researchers and practitioners in need of a comprehensive overview of muscle biology.

  • Recent Trends in Computer-aided Diagnostic Systems for Skin Diseases

    Theory, Implementation, and Analysis
    • 1st Edition
    • Saptarshi Chatterjee + 2 more
    • English
    Recent Trends in Computer-aided Diagnostic Systems for Skin Diseases: Theory, Implementation, and Analysis provides comprehensive coverage on the development of computer-aided diagnostic (CAD) systems employing image processing and machine learning tools for improved, uniform evaluation and diagnosis (avoiding subjective judgment) of skin disorders. The methods and tools are described in a general way so that these tools can be applied not only for skin diseases but also for a wide range of analogous problems in the domain of biomedical systems. Moreover, quantification of clinically relevant information that can associate the findings of physicians/experts is the most challenging task of any CAD system. This book gives all the details in a step-by-step form for different modules so that the readers can develop each of the modules like preprocessing, feature extraction/learning, disease classification, as well as an entire expert diagnosis system themselves for their own applications.

  • Lahita's Systemic Lupus Erythematosus

    • 6th Edition
    • Robert G. Lahita
    • English
    Systemic lupus erythematosus (SLE), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness.To date, lupus has no known cause or cure. Early detection and treatment are the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, antimalarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, like those used in the treatment of cancer, are also used to suppress the immune system in lupus patients. A new edition of this established and well-regarded reference combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus, Sixth Edition, is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a reference work for hospital libraries.

  • Human Aging

    From Cellular Mechanisms to Therapeutic Strategies
    • 1st Edition
    • Calogero Caruso + 1 more
    • English
    Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging. The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it.

  • Reciprocal Translation Between Pathophysiology and Practice in Health and Disease

    • 1st Edition
    • Peter B. Soeters + 1 more
    • English
    Reciprocal Translation Between Pathophysiology and Practice in Health and Disease brings a novel perspective, closing the knowledge gap between normal/abnormal physiology. Chapters describe the basic mechanisms underlying a disease or trauma-related response, describe consequences in practice, and provide insights on how to use information to better understand disease outcomes. Other sections explore how these responses are beneficial and driven by similar hormones and inflammatory immune cell derived modulators. This is a must-have resource for those seeking an authoritative and comprehensive understanding on how to treat the basic mechanisms underlying disease or trauma-related responses.With contributions from Petronella L.M. Reijven.

  • Aquaculture

    • 1st Edition
    • Volume 38
    • English
    Approx.364 pages

  • Introduction to the Constraints-Led Approach

    Application in Football
    • 1st Edition
    • Ben Bell
    • English
    Introduction to the Constraints-Led Approach: Application in Football is a coaching resource football coaches can use to understand key theoretical components of the constraints-led approach. Sections discuss ecological dynamics, perception-action, degrees of freedom and complexity theory. Examples are provided within theoretical chapters to assist readers in their practical application. Over 30 designed practices using the constraints-led approach show readers how the theory translates into practice. These are ordered by the aim of the practice, from in possession, to defensive transition, to out of possession and attacking transition. Currently, there are no books on the market covering the constraints-led approach specific to football. The aim is to make this book accessible to football coaches without the necessity to focus solely on academic theory.

  • In Situ Molecular Pathology and Co-expression Analyses

    • 2nd Edition
    • Gerard J. Nuovo
    • English
    Major advancements in the field of in situ molecular pathology have occurred since publication of the first edition. In Situ Molecular Pathology and Co-expression Analyses, Second Edition, continues to teach both the molecular basis for the improvements and the actual protocols. This is the unique feature that separates it from the pack of other "cook-book" type approaches. The fields of in situ hybridization and immunohistochemistry have expanded rapidly where computer-based analyses systems have greatly expanded the power of these methods. Further, knowledge of the marked improvements in the reagents themselves since the first edition can make the difference of excellent versus misleading data. The automated platforms require that researchers and diagnostic biomedical investigators have a good understanding of the basics of in situ based tests, protocols, and biochemistry for troubleshooting in order to maximize the use of these platforms. This second edition focuses attention on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. Practicing molecular pathologists, diagnostic pathologists, laboratory directors, and toxicologists, as well as clinicians and researchers in training, will benefit from this clear presentation of protocols and theoretical framework. Data derived from in situ hybridization and immunohistochemistry...

  • Tantalizing Therapeutics in Bronchopulmonary Dysplasia

    • 1st Edition
    • Vineet Bhandari
    • English
    Tantalizing Therapeutics in Bronchopulmonary Dysplasia is a concise reference that provides an overview of emerging concepts in the understanding of lung development and injury from a molecular and cellular point-of-view, including exciting pathways that are paving the way for new options to prevent or treat Bronchopulmonary Dysplasia (BPD). The book's chapters are written by experts who are at the forefront of BPD research. Coverage includes chapters on exosomes, stem cells and miRs, as well as a section on new discoveries in BPD research with translational potential. This is a must-have reference for researchers, physicians and trainees working on BPD, lung developmental biology, and more.

  • Comparative Kinesiology of the Human Body

    Normal and Pathological Conditions
    • 1st Edition
    • Salih Angin + 1 more
    • English
    Comparative Kinesiology of the Human Body: Normal and Pathological Conditions covers changes in musculoskeletal, neurological and cardiopulmonary systems that, when combined, are the three pillars of human movement. It examines the causes, processes, consequences and contexts of physical activity from different perspectives and life stages, from early childhood to the elderly. The book explains how purposeful movement of the human body is affected by pathological conditions related to any of these major systems. Coverage also includes external and internal factors that affect human growth patterns and development throughout the lifespan (embryo, child, adult and geriatrics). This book is the perfect reference for researchers in kinesiology, but it is also ideal for clinicians and students involved in rehabilitation practice.

  • Pangolins

    Science, Society and Conservation
    • 1st Edition
    • English
    Pangolins: Science, Society and Conservation brings together experts from around the world to document the most up-to-date scientific knowledge on pangolins and their conservation. It chronicles threats facing the species, explores the current initiatives required to protect them, and looks ahead at the future of pangolin science and conservation efforts. Led by a team of editors with more than 20 years collective experience in pangolin conservation, this book includes accounts of the species’ evolution, morphology, and systematics. It discusses the role of pangolins in historically symbolic, mythological, and ritualistic practices across Africa, Asia, and Europe, as well as contemporary practices including international trafficking. Chapters in the latter portion of this book focus on conservation solutions, including law enforcement and international policy, behavior change, local community engagement, ex situ conservation, tourism, and other interventions needed to secure the future of the species. Pangolins: Science, Society and Conservation is the latest volume in Elsevier’s species-specific series, Biodiversity of the World: Conservation from Genes to Landscapes. This book is a valuable resource for researchers and students in species conservation science, planning, and policymaking.

  • The Zebrafish in Biomedical Research

    Biology, Husbandry, Diseases, and Research Applications
    • 1st Edition
    • Samuel Cartner + 5 more
    • English
    The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research.

  • Biology and Physiology of Freshwater Neotropical Fish

    • 1st Edition
    • Bernardo Baldisserotto + 2 more
    • English
    Biology and Physiology of Freshwater Neotropical Fish is the all-inclusive guide to fish species prevalent in the neotropical realm. It provides the most updated systematics, classification, anatomical, behavioral, genetic, and functioning systems information on freshwater neotropical fish species. This book begins by analyzing the differences in phylogeny, anatomy, and behaviour of neotropical fish. Systems such as cardiovascular, respiratory, renal, digestive, reproductive, muscular, and endocrine are described in detail. This book also looks at the effects of stress on fish immune systems, and how color and pigmentation play into physiology and species differentiation. Biology and Physiology of Freshwater Neotropical Fish is a must-have for fish biologists and zoologists. Students in zoology, ichthyology, and fish farming will also find this book useful for its coverage of some of the world’s rarest and least-known fish species.

  • Encyclopedia of Gastroenterology

    • 2nd Edition
    • Ernst J. Kuipers
    • English
    Encyclopedia of Gastroenterology, Second Edition, Four Volume Set provides a comprehensive and concise reference on all aspects of gastroenterology and hepatology, including the organs in the gastrointestinal system, their functions in health and disease, and strategies or procedures to resolve or prevent problems and disease. This concise, up-to-date information includes comprehensive sections on the impact of nutrition, gastrointestinal microbiota, lifestyle, commonly used drugs, and surgical procedures on health and disease. Since the first edition, attention to the roles of nutrition and gastrointestinal microorganisms (microbiota, formerly Microbiota) in health and disease has skyrocketed. In addition, an entirely new section on obesity and diabetes is included.

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