Smart Organ-on-Chip Devices: Dynamic Microfluidic Systems for Cell Culture discusses the concepts to engineer functional stimuli responsive organotypic-on-chip devices and its application in several fields, including drug development, disease modeling, personalized medicine, and tissue engineering. Groundbreaking studies are presented throughout the book sections to reinforce the importance of adding more reliable and robust in vitro platforms able to closely emulate the dynamism of human physiology.The authors present new information regarding in silico studies of cell spheroids within microfluidic devices, as well as step-by-step guidance on key procedures. Written for researchers, practitioners and students using microfluidic devices as platforms, by well-respected scientists from both academia and industry.
Cryo-Electron Tomography: A Journey from Sample Preparation to Data Mining providing a holistic overview of this rapidly advancing field and equipping researchers with the knowledge and tools necessary to initiate their own investigations. The book begins with a section on advanced cryogenic sample preparation for in situ cellular tomography, covering a range of sample types including viruses, bacteria, eukaryotic cells, and perspectives for organoids and tissues. Specific chapters focus on essential approaches such as vitrification, sample thinning, and bimodal correlative techniques. The book then transitions to a section on data mining and validation.
Ultra Widefield Imaging of the Retina covers basic anatomy and physiology of the retina, providing the technical aspects of ultra widefield retinal imaging that give readers a strong grounding in the discipline’s central tenets. The book provides a comprehensive view of the peripheral retina, enabling better detection of pathology and more accurate assessment of disease progression. It fills the knowledge gap among healthcare professionals with regard to principles, procedural aspects, and clinical applications of these innovations. In essence, anyone seeking in-depth information on imaging and the treatment of vascular chorioretinal disorders, inflammatory disorders, and chorioretinal tumors will find it here.New imaging modalities, improved image quality, and enhanced analysis techniques have proven valuable tools in the diagnosis and management of retinal diseases, hence this book will serve as a resource for clinicians and researchers to stay up-to-date in this rapidly evolving field.
Space Biology and Space Biotechnology provides the reader with a wide-ranging review of space biology and related fields. The topics covered include space environment, space microbiology, space botany, space hydrobiology, space physiology, space development, space ecology, space cell animal and tissue engineering, space simulation technology, and space pharmaceuticals. Written for professionals in biology and biotechnology, graduate students and post-docs, as well as spaceflight professionals in industry, academia and government, by experts and scholars in the field of space biology and space biotechnology.
Training in clinical chemistry is acquired via different avenues that include didactic lectures on pathophysiology of disease, methodologies and practical aspects of testing, and through attendance of operations meetings, sign-out sessions, seminars and tutorials. There is little instruction on how to apply the vast amount of knowledge gained in the process to practice. In other branches of medicine, cases are regularly presented with clinical information and therapeutic interventions which form the basis of training. Diagnostic Reasoning: Laboratory-Based Case Studies in Clinical Chemistry fills this gap for clinical chemistry. The concise and practical approach of the book, including real-life scenarios, is an excellent resource for pathology trainees, clinical laboratory science students, clinical chemistry fellows, clinical laboratory professionals, and clinicians. These cases help professionals remain competent in the field and be successful in their board exams. The cases are stated as they present, often with no or few clinical details accompanying the sample request with only barcoded samples arriving into the laboratory. In a busy laboratory, thousands of these cases are received daily and it is impossible to review the clinical information associated with the specimens.
Carotid Artery Disease is a practical resource for those who need a detailed understanding of pathophysiologic and hemodynamic mechanisms that lead to development of atherosclerotic plaque which can provide a fertile environment to scientists for further discoveries. It provides the most up to date clinical practice and opinions from leading medical doctors who manage carotid artery disease. This book provides the most recent utilized diagnostic and treatment modalities, as well as clear guidelines pertinent to special diagnostic considerations and emerging novel surgical and non-surgical treatment techniques.
Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes was the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies.Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices. Contributions from scientists, clinicians, and engineers who are the leading figures in their respective field’s present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field.New coverage will include signaling pathways for tendon development, molecular mechanisms of tendinopathy, inflammation contribution to healing and pathology of tendons, tendon aging and degeneration, tendon models, and translational studies for tendon regenerative medicine.
6G-Enabled Technologies for Modern Society: Fundamentals, Applications, Analysis and Challenges serves as a comprehensive reference, addressing the information needs of professionals by providing deep information about the fundamentals and applications of 6G, enabling them to make informed decisions in the dynamic landscape of advanced communication technologies. In 24 chapters the book introduces the reader to the 6G technology, the evolution of wireless communication, the integration of artificial intelligence, provides Use Cases and Applications of 6G Technology, and insights into the challenges, future trends and emerging technologies includes the applications of 6G technology in remote healthcare services, patient monitoring, and medical diagnostics.6G-Enabled Technologies for Modern Society: Fundamentals, Applications, Analysis and Challenges redefines the way we connect, communicate, and collaborate with emerging technologies in this smart era of 6G technology. The title benefits from a collective wealth of knowledge and perspectives. This diversity enriches the content, providing readers with insights from various angles, setting it apart from publications authored or edited by a limited number of individuals.
Tumour-Targeting with Stimuli Responsive Vesicular Nanocarriers: Basics to Emerging Applications not only acquaints scientists and science interns with the fundamental knowledge of the experimental aspects and state-of-the-art technology for vesicular carriers to equip their rational application in tumor targeting, but also provides a holistic understanding of regulatory concerns, patents, and clinical trials. In 15 chapters. this book provides basics and advances in stimuli-responsive vesicular carriers for tumor targeting based on findings outlined in highly organized tables, illustrative figures, and flow charts.With a focus on the extrapolation of bioengineering tools in the domain of vesicular carriers, stimuli-responsive features concerning tumors, drug delivery approaches, and associated challenges, it helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries in therapy, diagnosis, and theragnosis of cancer.
Atlas of Endoscopy Imaging in Inflammatory Bowel Disease, Second Edition, serves as a comprehensive guide to the latest advancements in IBD. This new edition keeps readers updated with cutting-edge medical treatments, state-of-the-art endoscopy, and imaging technologies, as well as the evolution of interventional IBD. It explores the latest advancements in IBD diagnosis and management, including the most recent endoscopy instruments for measuring disease activity and the transformative world of image-enhanced endoscopy. Additionally, it delves into the groundbreaking application of Artificial Intelligence (AI) in IBD, revolutionizing diagnosis, disease monitoring, and dysplasia surveillance. New content introduces a range of topics to stay at the forefront of Inflammatory Bowel Disease (IBD) knowledge. These include Intestinal Ultrasound, Device-Associated Enteroscopy in Crohn’s Disease, insights into IBD-Like Conditions (Autoinflammatory Disorders), and the value of Intraoperative Endoscopy in IBD procedures. The book also integrates New Consensus Guidelines for Endoscopy Imaging in IBD, explores the Applications of Artificial Intelligence (AI) in IBD diagnosis and monitoring, addresses the intersection of COVID, COVID Vaccines, and IBD, and presents New Applications of Interventional IBD techniques. This second edition serves as a dynamic repository of state-of-the-art information, providing invaluable insights on differential diagnosis, advanced endoscopy, and imaging technologies, with a pronounced focus on AI. It also offers updated guidelines for disease activity assessment and the latest advancements in endoscopic therapy modalities. Designed to cater to a diverse range of medical professionals, it stands as an indispensable reference, fostering a comprehensive and up-to-date understanding of Inflammatory Bowel Disease (IBD). Within these pages,Gastroenterologists and IBD specialists will discover a wealth of resources to aid their pursuit of cutting-edge treatments and AI-driven insights. Primary care clinicians will find an expanded list of differential diagnoses that enables more accurate early-stage identification. Surgeons can elevate their expertise by delving into the intricacies of interventional IBD techniques, while pathologists and radiologists can enhance their diagnostic skills through AI and image-enhanced endoscopy. This comprehensive resource ensures that medical professionals across various disciplines are well-equipped to navigate the evolving landscape of IBD diagnosis, treatment, and management.