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Books in Life sciences general

Providing a broad overview of biological systems, ecology, evolution, and molecular biology, this selection supports researchers, educators, and students across life sciences. It features foundational concepts, recent advances, and interdisciplinary approaches that promote comprehensive understanding and innovative research in the biological sciences.

  • Current Approaches to Overcome Therapeutic Resistance of Leukemia

    • 1st Edition
    • Zhe-Sheng Chen + 2 more
    • English
    Current Approaches to Overcome Therapeutic Resistance of Leukemia presents a comprehensive academic resource addressing the persistent challenge of treatment resistance in leukemia. It explores biological, molecular, and clinical dimensions of resistance, bridging fundamental research with therapeutic innovation. The book examines key resistance mechanisms, including genetic mutations, leukemic stem cells, and tumor microenvironment interactions, alongside emerging insights such as epigenetic regulation, metabolic reprogramming, and immune evasion. It further highlights advanced therapeutic approaches, including immunotherapy, targeted therapies, combination strategies, and AI-driven tools for drug discovery and monitoring. This volume provides students, researchers, and clinicians with foundational and integrated knowledge essential for understanding resistance biology and translating discoveries into clinical practice. It supports evidence-based decision-making and promotes the development of innovative strategies to improve patient outcomes.
  • AI and Global Health

    Unlocking Transformative Potential
    • 1st Edition
    • Adil Haider
    • English
    AI and Global Health: Unlocking Transformative Potential provides a roadmap for practitioners to apply and leverage artificial intelligence to strengthen health systems using the World Health Organization's health systems approach. The book's combination of case studies and secondary research inspires the possibility of what can happen using AI in healthcare, ensuring the use of robust, scientific evidence to draw conclusions. Additionally, readers will learn from others in settings where AI has been a tool for change, providing healthcare practitioners and policymakers with what they need to think through how it can be applied in resource limited settings.The book provides a strong call to action for policymakers and healthcare leaders of governments, international organizations, and healthcare institutions to take the lead in AI implementation as a key lever for advancing global health goals through a systems approach. As AI is a rapidly evolving field with significant investment made in this industry in recent years from government and the private sector, this book articulates how this growth can be harnessed for countries that need a different approach to addressing global health problems.
  • Childhood Disorders of Rickets and Osteomalacia

    A Comprehensive Review
    • 1st Edition
    • Suma Uday
    • English
    Childhood Disorders of Rickets: A Comprehensive Review defines the pathophysiology of rickets and the various genetic and acquired conditions that present with rickets in childhood. This comprehensive review details the various forms of rickets, the histopathology, recent advances leading to new therapeutic options in treating rickets, and the role of Vitamin D and calcium in nutritional rickets. Additionally, the authors explore future research in various areas of nutritional and non-nutritional forms of rickets.Written by global experts for clinicians and researchers treating and studying the various forms of rickets, the book will also be of interest to those working in public health and policy makers working on the prevention of nutritional rickets worldwide.
  • Operative Strategies in Pelvic Exenteration Surgery

    • 1st Edition
    • Michael E Kelly + 1 more
    • English
    Operative Strategies in Pelvic Exenteration Surgery is a reference for the surgical management of Pelvic Exenteration Surgery. It covers all aspects of surgery from the colorectal, urological, gynecological, and orthopedic point of view. Coverage consolidates the research of world-leaders and includes the history of exenterative study, outlining the current state and indicating future developments. The book also discusses the current surgical operative strategies for the management of locally advanced and recurrent pelvic neoplasms with illustrations, intra-op photos, and supplementary video material.Created from the experiences of an international collaboration of surgeons, this reference is the perfect reference for surgical oncologists, colorectal, gynecology, urology, and vascular surgeons as well as any group involved in complex pelvic surgery including complex open, laparoscopic, and robotic surgery.
  • Emergent Nanotherapeutics in Diabetic Complications

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Emergent Nanotherapeutics in Diabetic Complications explores how cutting-edge nanotechnology is transforming the treatment of diabetes-related disorders beyond glycemic control. This comprehensive volume examines targeted, multifunctional nanoplatforms designed to address the wide range of comorbidities linked to diabetes, including vascular complications, metabolic dysfunctions, and impaired wound healing. Structured in five parts, the book spans from current nanoformulation strategies to emerging innovations such as CRISPR-Cas9 delivery, AI-guided nanoparticles, and 3D/4D printed nanostructures.Bridg... the gap between preclinical research and clinical application, it offers valuable guidance on stimuli-responsive systems, biocompatible materials, and regulatory pathways. This is essential resource for medical professionals, biomedical engineers, and pharmaceutical scientists seeking scalable, next-generation solutions for managing diabetic complications through nanomedicine.
  • The Evolution of Artificial Intelligence in Healthcare and Medicine

    From Basic Methods to Clinical Practice
    • 1st Edition
    • Mario Cannataro
    • English
    The Evolution of Artificial Intelligence in Healthcare and Medicine: From Basic Methods to Clinical Practice explores revolutionary technological advancements in the medical and healthcare realms due to generative AI and Deep Learning. This comprehensive guide not only explores cutting-edge technologies such as transformers and large language models for newcomers but also demystifies advanced applications like sequential decoding techniques and segmentation algorithms rarely explored in other literature. Sections cover foundational concepts and terminologies, explore deep learning and generative AI, provide AI's role in biomedical research, examine its integration into clinical practice, scrutinize its applications in public health, and discuss challenges and future prospects.This is an indispensable resource for healthcare professionals, scientists, researchers, students, and enthusiasts seeking to deepen their understanding of this rapidly evolving field.
  • Current Advances in Cancer Stem Cells and Neoplasia Research

    • 1st Edition
    • Volume 8
    • Hirendra Banerjee
    • English
    Cancer, Volume 8 in the Stem Cell Innovation in Health and Disease series explores the rapidly evolving role of stem cells in cancer treatment. As cancer continues to impose a heavy global health burden, stem cell therapies are being recognized for their regenerative potential and ability to enhance recovery following aggressive therapies. Hematopoietic stem cell (HSC) transplantation is already a standard, FDA-approved treatment for hematologic cancers such as leukemia, myeloma, and lymphoma. These cells help regenerate healthy blood cells post-treatment. In addition, mesenchymal stem cells (MSCs) and neural stem cells (NSCs) are showing promise in preclinical models as therapeutic carriers, capable of homing to tumor sites and delivering anti-cancer agents such as nanoparticles, siRNAs, and small-molecule drugs. Recent clinical advancements include differentiation therapy, where stem cells are used to induce cancer cells to become non-cancerous. Two completed phase I clinical trials have demonstrated innovative applications: one using NSCs to convert a prodrug into a toxic compound within tumors, and another using MSCs engineered with viral enzymes to activate cytotoxic drugs directly at the tumor site. MSCs have also helped reduce graft-versus-host disease (GVHD), a major complication of stem cell transplants. This volume is divided into two main sections: understanding stem cell roles in cancer biology, and translating stem cell innovations into clinical practice. It features cutting-edge research, including organoid models, genetic editing, and iPSC technologies. Together, these insights offer a timely review of the field’s progress and its real-world potential to reshape cancer therapy.
  • Trauma During Pregnancy

    • 1st Edition
    • Jorge Hidalgo + 2 more
    • English
    Surgical Care of the Critically Ill During Pregnancy, a volume in the Critical Care Obstetrics series, is a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women in all surgical aspects including trauma. The book's authors offer best practices and evidence-based material explicitly focused on the most common complications in pregnant patients that may occur to improve patient care. It not only covers critical care investigation from medical-surgical complications that any patient can present, but also how to prepare and anticipate complications in the critical care unit.
  • Laboratory Sleep Medicine

    Fundamentals of Sleep Technology
    • 1st Edition
    • Ravi Gupta + 2 more
    • English
    Laboratory Sleep Medicine: Fundamentals of Sleep Technology, is the second of the Fundamentals of Sleep Technology series, discusses balancing the fundamentals of sleep medicine with the newest innovations in the lab. High priority is given to practices that must be followed in sleep labs to guarantee the safety of patients and workers. To make information straightforward and easy to grasp, key events in each epoch of polysomnography are showcased. This serves to walk sleep professionals cogently through the history of sleep technology advancement.Laborato... Sleep Medicine: Fundamentals of Sleep Technology is keenly aware that manual titration with PAP is the gold standard treatment for sleep apnea. However, certain patients may require oxygen treatment, which is also covered in depth. In addition, case vignettes illustrate the development of a relevant report using the following: data from a sleep diary, actigraphy, and polysomnography. How to do sleep tests in unusual situations (such as at-home sleep apnea testing and testing in an intensive care unit) are also covered.
  • Pain Conditions of the Head and Face

    A Practical Guide to Diagnosis and Management
    • 1st Edition
    • Anat Galor + 1 more
    • English
    Pain Conditions of the Head and Face: A Practical Guide to Diagnosis and Management provides a user-friendly guide on diagnosing and managing common head and facial pain conditions using new methods and therapies. The book contains practical information, reviewing epidemiology, presenting key features, contributing mechanisms, and including treatment algorithms for common pain conditions of the head and face. Focus is given to aspects of disease that are novel and evolving, and all conditions are discussed within the framework of the latest advances in research and patient care.Doctors seeking to ameliorate their patients’ pain from such maladies as (among many others) neuropathic ocular pain, trigeminal neuralgia, herpetic neuralgia, temporomandibular disorders, burning mouth disorder, and neuropathic ear pain will require no other book to identify their patients’ illnesses and make sure they receive the care they need.
  • Dry Eye Disease

    A Clinical Handbook
    • 1st Edition
    • James Stuart William Wolffsohn + 2 more
    • English
    Dry Eye Disease: A Clinical Handbook illuminates the translation of cutting-edge research on dry eye disease into practical situations, allowing clinical diagnosis and management of the condition using the latest evidence-based methods. It first presents research on the core pathophysiological features of dry eye disease, including tear film instability, hyperosmolarity, inflammation, and ocular surface damage. Thereafter, it champions a patient-centered approach to dry eye management, emphasizing the necessity of classifying the ocular surface disease(s) most relevant to each case. It discusses global disease distribution and the role of non-modifiable risk factors like age, sex, and ethnicity. Additionally, the book describes tools for monitoring symptoms over time and assessing subtle signs of the disease. Readers will find practical methods for improving patient outcomes both in clinical settings and at home.
  • Bioinformatics Essentials II

    From Multi‑omics to AI – Methods, Workflows, and Translational Applications
    • 1st Edition
    • Syed Mudasir Ahmad + 2 more
    • English
    Bioinformatics Essentials II, From Multi‑omics to AI – Methods, Workflows, and Translational Applications offers a comprehensive guide to modern bioinformatics, focusing on best-practice workflows for multi-omics data analysis and AI-assisted discovery. Designed for learners and early-career researchers, it bridges foundational knowledge with cutting-edge applications. The book covers experimental design, sequencing technologies, and core omics workflows including transcriptomics, proteomics, metabolomics, and epigenomics. Advanced chapters explore single-cell and spatial omics, multi-omics integration, AI/ML applications, and environmental bioinformatics.Each chapter includes learning objectives, worked examples, toolbox comparisons, and reproducible code. This resource empowers students, faculty, and applied researchers to confidently analyze complex datasets and translate findings into agriculture, health, and environmental solutions. Its modular structure and companion website enhance usability in both coursework and independent study.
  • Biofeedback and Pain Management

    A Clinical Guide
    • 1st Edition
    • Anu Kotay
    • English
    Biofeedback and Pain Management: A Clinical Guide provides a detailed understanding of the psychophysiology of chronic pain, biofeedback treatments, the realities of living life with chronic pain limitations, and the role of pain in our lives and society. The book covers evidence on the effective uses of biofeedback interventions for pain management, including protocols, as well as case-based examples and strategies practitioners can use in real-life settings. Sections define biofeedback, including illustrations that depict how biofeedback is a useful part of any pain management treatment plan, cover procedures based on evidence and case examples, and present the social context of chronic pain.
  • Biomaterials in Cancer Therapy

    Innovations and Applications
    • 1st Edition
    • Alok Raghav
    • English
    Biomaterials in Cancer Therapy: Innovations and Applications explores the critical role of functional biomaterials in addressing one of today’s most pressing health challenges—cancer. Despite advancements in therapies, cancer continues to claim millions of lives annually, necessitating innovative approaches that integrate engineering and pharmaceutical sciences. This book highlights the potential of engineered biomaterials to enhance drug delivery, minimize side effects, and promote tissue regeneration, ultimately improving patient outcomes. The content examines cutting-edge innovations in functional biomaterials, including their applications in targeted drug delivery and immunotherapy, while emphasizing the role of nanotechnology in developing effective cancer theranostics with minimal toxicity. Targeted at academicians, physicians, and industry professionals, this book serves as a vital resource for understanding the transformative potential of functional biomaterials in oncology. By addressing real-world challenges and incorporating diverse perspectives, it inspires innovative solutions that enhance global healthcare outcomes for cancer patients.
  • Health Impacts of Climate Change

    A Global Perspective
    • 1st Edition
    • Mohammad Hadi Dehghani + 2 more
    • English
    Health Impacts of Climate Change: A Global Perspective confronts the most urgent reality of our time: the climate crisis is, at its core, a health crisis. Drawing from the latest research in climate science, public health, and policy, this book offers a comprehensive, interdisciplinary look at how global warming is already endangering lives—and what can be done to protect them. Readers will gain a deep understanding of direct health threats like heatstroke, air pollution, and disaster-related trauma, as well as the less visible dangers: rising zoonotic diseases, crop failures leading to malnutrition, and mental health challenges driven by climate-induced displacement.What sets this book apart is its unwavering focus on equity. It explores how climate change disproportionately impacts the most vulnerable—low-incom... communities, people in the Global South, and marginalized groups—who contribute the least to global emissions but bear the brunt of the damage. Through case studies, personal narratives, and policy analysis, the book amplifies frontline experiences and calls for climate justice as an essential part of any effective health response. From practical strategies for healthcare professionals to frameworks for policymakers, this book empowers a wide range of readers—from students and researchers to community leaders and concerned citizens.
  • Human Reproduction

    From basics to Biotechnology
    • 1st Edition
    • Marc yeste
    • English
    Human Reproduction: From Basics to Biotechnology is a complete reference for anyone in the field of life, health, and biomedical sciences. The book provides an overview of basics in human reproduction to advanced knowledge of the field, including some evidence from other mammalian species that complement our current knowledge on the anatomy and physiology of the male and female reproductive tract and gametes. This resource covers the most used assisted reproductive techniques and technical advances, human reproduction and infertility disorders, their diagnosis and available treatment options.
  • Advances in Medical Simulation

    Techniques, Applications and Innovations
    • 1st Edition
    • Noor Zaman Jhanjhi + 2 more
    • English
    Advances in Medical Simulation: Techniques, Applications, and Innovations explores cutting-edge developments in medical simulation, focusing on its transformative role in medical education, training, and patient care. The book examines various simulation techniques, including virtual and augmented reality, high-fidelity mannequins, and task trainers, showcasing their applications in surgical training, clinical diagnostics, and emergency response. Sections provide an in-depth discussion of the challenges and future directions in medical simulation, highlighting innovations such as robotics and artificial intelligence. By addressing gaps in existing literature, this book offers a comprehensive understanding of how advanced simulation techniques can enhance healthcare professionals' skills and competencies.For the academic audience, this book serves as a vital resource that bridges research and practical applications in clinical settings. It identifies trends and opportunities for future innovation, ultimately aiming to reduce medical errors and improve patient safety through effective simulation-based practices.
  • Nanotechnology in Brain Tumor Treatment

    Unveiling Molecular Mechanisms and Pioneering Therapies
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Nanobiotechnology in Brain Tumor Treatment: Unveiling Molecular Mechanisms and Pioneering Therapies is a groundbreaking resource that addresses the formidable challenges posed by brain tumors in oncology. This comprehensive book explores the etiology, symptoms, diagnosis, and treatment options for brain tumors, with a particular focus on the revolutionary impact of nanobiotechnology. By integrating cutting-edge research on nanotechnology with practical applications in neuro-oncology, this book offers a unique perspective on enhancing patient outcomes and advancing brain cancer treatment strategies.By offering a comprehensive overview of nanobiotechnology in brain tumor treatment, this resource serves as a vital tool for those involved in the research, diagnosis, and treatment of brain cancers, paving the way for innovative and personalized therapeutic approaches.
  • Space Physiology

    From Earth to Space and Back Again
    • 1st Edition
    • Alan Hargens
    • English
    Space Physiology: From Earth to Space and Back Again provides readers with new and authoritative information about current and important topics related to risks and their countermeasures in space.This book covers translation of Earth-based physiology to astronaut health and Earth applications of space research. Topics include adaptations of various systems to space, including bone, microcirculation, microcirculation, skeletal and smooth muscles, headward fluid shifts, vision as well as integrated countermeasures to maintain well-being and health in space.This is a volume in Elsevier’s series Hot Topics in Physiology, published in association with the International Union of Physiological Sciences. It is an ideal reference for academics and researchers (space physiology and medicine, space radiation, rehabilitation medicine, exercise, wound healing, biochemistry and cell biology, molecular biology) at undergraduate, masters, PhD, and Post-Doc levels.
  • Essentials of Medical Coordination in Complex Humanitarian Emergencies

    • 1st Edition
    • Joanna Kotcher
    • English
    Essentials of Public Health and Medical Coordination in Complex Humanitarian Emergencies provides a practical overview for health coordinators in assessing, coordinating, and implementing medical and public health responses in disaster and conflict environments. The book aims to achieve this in two parts. Part one covers foundational information such as the role of the coordinator; project assessment and start-up; standards, protocols, and guidelines; project strategy and accountability; and basic epidemiological measurements and tools. Part two goes on to discuss the implementation of programs and services like nutrition, mental health and psychosocial support (MHPSS), management of chronic disease, community health promotion, sexual and reproductive health, health information systems and disease surveillance. A health coordinator in the field is required to quickly assess the needs of a population in a humanitarian emergency, initiate start-up procedures, and coordinate the response over a period of months or longer. The efficiency and effectiveness of this process depends on the experience, knowledge, and skills of the coordinator, Essentials of Public Health and Medical Coordination in Complex Humanitarian Emergencies is a resource for those in the medical, public health, and international humanitarian aid sectors who care about the health of populations at risk and is written by an author who has coordinated emergency response in conflict environments in Kosovo, Central Asia (Tajikistan), Afghanistan, Darfur, Gaza and the OPT, Somaliland, Syria, and Iraq.
  • Advanced Nanofiber Technology in Cancer Management

    • 1st Edition
    • Goutam Rath + 2 more
    • English
    Advanced Nanofiber Technology in Cancer Management presents a comprehensive exploration of nanofiber-based systems for cancer therapy and diagnostics. It bridges pharmaceutical sciences, nanotechnology, and oncology to address the challenges of targeted drug delivery and systemic toxicity. The book covers biopolymer, peptide, carbon, and metal nanofibers, detailing their fabrication, characterization, and application in chemotherapy, immunotherapy, gene therapy, and photothermal treatment. It also explores diagnostic innovations such as biosensors and imaging-guided systems, alongside AI and 3D printing in nanofiber development. This volume benefits researchers, clinicians, and pharmaceutical developers by offering translational insights, regulatory perspectives, and real-world case studies. It supports informed decision-making in cancer management and product development.
  • Emerging Technologies in Bioengineering for Oncology

    Fundamentals, Research, and Future Prospects
    • 1st Edition
    • Saikat Das + 2 more
    • English
    Emerging Technologies in Bioengineering for Oncology: Fundamentals, Research, and Future Prospects explores the integration of engineering, biology, and medicine to tackle challenges in developing innovative tools for cancer diagnosis and treatment. This comprehensive resource addresses the evolving landscape of bioengineering in oncology, highlighting the intersection of various disciplines to drive advancements in diagnostic and therapeutic approaches. The book explores a range of cutting-edge technologies such as lab-on-chip devices, wearable biosensors, 3D bioprinting, and targeted nanomedicine, offering promising avenues for enhanced diagnostic precision, treatment effectiveness, and personalized healthcare.Geared towards medical students and professionals, the book provides detailed insights into the latest developments, practical applications, and future research directions in the field. By offering a deep dive into the realm of bioengineering for oncology, it serves as a valuable asset for those seeking to advance cancer care through interdisciplinary collaboration and innovation.
  • Endoscopic Ultrasound in Pancreatic Diseases

    Best Practices and Recent Innovations in Technology and Techniques
    • 1st Edition
    • Masayuki Kitano
    • English
    In Endoscopic Ultrasound in Pancreatic Diseases: Best Practices and Recent Innovations in Technology and Techniques, leading experts share their insights, best practices, and the latest technological innovations revolutionizing the approach to pancreatic diseases. This practical reference provides step-by-step guidance, case presentations, and detailed images and procedures on advanced techniques in diagnosis and treatment with endoscopic ultrasound for pancreatic diseases.Organized into four sections, this book reviews the latest advances in endoscopic ultrasound equipment, techniques, complications, scanning methods, microbubbles and contrast harmonic imaging, elastography, fine needle tissue acquisition, and classification and safety management of interventional endoscopic ultrasound. Tumor detection, characterization, and diagnosis are reviewed, and pancreatic diseases treatment and intervention methods are covered extensively. The book concludes with the examination of groundbreaking methods and discussion of education and future directions. Endoscopic Ultrasound in Pancreatic Diseases: Best Practices and Recent Innovations in Technology and Techniques fully equips endoscopists with the most recent developments in endoscopic ultrasound and is a vital resource for navigating the evolving landscape, enabling practitioners to excel in advanced clinical practices and contribute to the field’s growth.
  • Lifestyle Medicine

    Lifestyle, the Environment and Preventive Medicine in Health and Disease
    • 4th Edition
    • Michael Sagner
    • English
    Lifestyle Medicine: Lifestyle, the Environment and Preventive Medicine in Health and Disease, Fourth Edition aims to reduce the burden of chronic diseases by harnessing technology and providing a better understanding of environment-biology interactions, evidence-based interventions, and the underlying mechanisms of chronic diseases. This new edition is greatly expanded to cover major chronic diseases as well as infectious diseases. Led by top experts in the field, the editors provide a framework to promote and facilitate multi-stakeholder collaboration with an orchestrated common language and an integrated care model to increase the population’s heath span.The book provides the latest research updates on the pathophysiology of preventable diseases, Clinical updates on interventions for practice, and Public health updates on Precision Medicine / Systems Biology approaches to prevention for clinicians and Interdisciplinary aspects for allied health professionals. It is essential to healthcare professionals who want to: understand the potential of preventing diseases; understand how to maintain health and well-being; understand the implications of preventable diseases for society and individuals; and understand lifestyle aspects in the prevention and treatment of diseases.
  • An Essential Guide to Radiation Dosimetry for Medical Applications

    Principles, Technologies, and Clinical Applications
    • 1st Edition
    • Jayachandran Venkatesan + 1 more
    • English
    An Essential Guide to Radiation Dosimetry for Medical Applications: Principles, Technologies, and Clinical Applications provides a comprehensive overview of the fundamental concepts, advanced methodologies, and emerging technologies in radiation dosimetry. This book serves as an essential resource for researchers, clinicians, and students involved in cancer research, bioinformatics, medical physics, radiology, material scientists and radiation therapy, offering in-depth insights into both theoretical principles and practical applications. The content covers core topics such as radiation interactions, dosimetry materials, and simulation techniques, alongside clinical and diagnostic applications.In addition, it also explores innovative approaches like artificial intelligence, nanodosimetry, and quality assurance, ensuring readers stay current with technological advancements. This book benefits the academic audience by enhancing their knowledge of dosimetry science and fostering the development of safer, more effective radiation practices. It supports education, research, and clinical decision-making, ultimately advancing the field of radiation physics and improving patient outcomes.
  • Leveraging AI and ML in Cardiovascular Diagnosis and Management

    • 1st Edition
    • Rosaline Mishra + 3 more
    • English
    Leveraging AI and ML in Cardiovascular Diagnosis and Management examines how artificial intelligence and machine learning transform cardiovascular care. It gathers chapters from leading researchers to bridge clinical practice with cutting-edge analytics, imaging, and decision support. The volume details core topics across the field, including fundamentals of AI/ML, AI-driven cardiovascular imaging, predictive analytics for risk stratification, heart failure management, arrhythmia detection, wearable-enabled monitoring, and the integration of multi-omics with clinical data. It also addresses neurocardiology, clinical decision support systems, ethics, and regulatory considerations, all framed for cardiovascular scientists and clinicians. For academics, clinicians, and educators, the book offers actionable workflows, a cohesive framework for translating AI and ML advances into improved diagnosis, treatment personalization, and patient outcomes across diverse populations.
  • Theranostics for Cancer Targeting

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    This groundbreaking Theranostic book delivers the definitive roadmap for the next generation of precision oncology by systematically detailing the clinical, regulatory, and drug delivery landscapes of theranostics—the revolutionary integration of therapy and diagnostics—across 20-22 major cancer types. Designed for medical publishers, clinicians, and biotech researchers, this chapter is a structural framework for each malignancy, bridging laboratory breakthroughs in nanotechnology, green nanochemistry, drug delivery, diagnostics, and AI with real-world clinical applications. It serves as an essential commercial and academic asset, offering unprecedented depth on FDA/EMA regulatory hurdles, technology transfer pathways, and actionable data tables that track active clinical trials and global research groups. By addressing key market trends and regulatory challenges, it serves as an essential, multidisciplinary resource for driving personalized oncology and improving patient outcomes
  • Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases

    • 1st Edition
    • Riccardo De Robertis
    • English
    Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases addresses the critical need for detailed comparisons between advanced ultrasound (US) techniques and CT/MRI findings in the evaluation of liver diseases. While many books exist, few provide the in-depth analysis and practical guidelines necessary for accurate diagnosis and effective treatment planning. This book fills that gap, offering a multiparametric approach to the assessment of fibrotic and steatotic liver diseases. Inside, readers will find essential topics such as indications for liver US in diffuse liver diseases, advanced Ultrasound techniques for assessing liver fibrosis and steatosis, and the correlation between US, CT, and MRI findings.Key chapters cover the basics of liver ultrasound, conventional Doppler and microvascular flow imaging, ultrasound elastography, and the quantification of liver steatosis. Additionally, the book explores cutting-edge topics like artificial intelligence in liver ultrasound and the application of US in pediatric patients. Contributions from leading experts in the field ensure that each chapter provides valuable insights and practical advice. This is an indispensable resource for scientists, researchers, and clinicians alike. It offers clear guidelines on performing liver ultrasounds, understanding and interpreting results, and making informed comparisons with CT and MRI findings.
  • Bioinformatics, Computational Biology, and Multi-Omics–Driven Probiotic Design for Gut Microbiome Engineering

    • 1st Edition
    • Naheed Mojgani + 3 more
    • English
    Bioinformatics, Computational Biology, and Multi Omics–Driven Probiotic Design for Gut Microbiome Engineering presents an interdisciplinary framework for applying artificial intelligence to microbiome science, probiotic development, and personalized nutrition. The book integrates bioinformatics, computational biology, and clinical insight to address current challenges in gut microbiome research and translation. The volume covers AI driven microbiome profiling, multi omics integration, computational modeling of host–microbe interactions, and predictive analytics. It progresses from foundational concepts to advanced applications, including AI assisted probiotic design, gut–brain axis research, regulatory considerations, and real world case studies supporting translational and clinical relevance. The book equips bioinformaticians, translational microbiome researchers, and clinician scientists with actionable methodologies, conceptual clarity, and validated examples. It supports evidence based decision making, accelerates translational research, and bridges discovery science with implementation in personalized nutrition and probiotic innovation.
  • Wilson and Mulcahy’s Prosthetic Urology

    A Comprehensive Guide to Surgery for Erectile Dysfunction and Male Incontinence
    • 1st Edition
    • Jay Simhan + 1 more
    • English
    Wilson and Mulcahy’s Prosthetic Urology: A Comprehensive Guide to Surgery for Erectile Dysfunction and Male Incontinence is a comprehensive reference that covers the surgical management of erectile dysfunction and male incontinence.This book's chapters cover a wide range of topics, including the history of penile prostheses, practice considerations, patient selection, placement techniques for malleable and inflatable penile prostheses, management of complications, and infection prevention and management. Additionally, specialized topics such as managing Peyronie's disease, priapism, and penile prosthesis placement in transgender patients are also addressed.Written by esteemed experts in the field, this reference offers valuable insights and guidance for healthcare professionals. Whether you are a practicing prosthetic urologist, a trainee looking to enhance your skills, or a device manufacturer aiming to improve surgical quality, this essential reference will elevate your knowledge and expertise.Tibor Imley's cover photo features Dr. Wilson and Dr. Mulcahy, after whom this title is named. This book honors their pioneering contributions to prosthetic urology.
  • Capsule Endoscopy in Pediatric Patients from Theory to Practice

    • 1st Edition
    • Thomas M. Attard
    • English
    Capsule Endoscopy in Pediatric Patients from Theory to Practice is a practical and authoritative guide that empowers pediatric gastroenterologists, physicians, and trainees to navigate the complexities of Video Capsule Endoscopy (VCE) in children. With a focus on bridging knowledge gaps and providing practical insights, this book offers updated information on understanding and utilizing VCE in the pediatric population. The book covers the background and technical aspects of VCE, including guidance on setting up a pediatric VCE service and an overview of indications and limitations. It delves into practical aspects such as preprocedural preparation, artifact reduction techniques, and management of capsule retention. By exploring VCE in various disease conditions such as inflammatory bowel disease, gastrointestinal bleeding, hereditary polyposis syndromes, and chronic abdominal pain, readers gain a comprehensive understanding of diagnosis, surveillance, and management. Special content elements, including key terms, case studies, and a timeline of recent advances, enhance the learning experience. This essential resource empowers readers to optimize patient care, make informed decisions, and confidently navigate the realm of VCE in children.
  • Biopolymer-Based Therapeutics for Inflammation Modulation in Wound Care

    • 1st Edition
    • Neha Raina + 2 more
    • English
    Biopolymer-Based Therapeutics for Inflammation Modulation in Wound Care presents a comprehensive, biomarker-driven exploration of how natural and engineered biopolymers are transforming the management of acute, chronic, and non-healing wounds. Positioned at the intersection of biomaterials science, pharmaceutical innovation, and clinical practice, the book addresses one of the central challenges in wound care: persistent inflammation that delays tissue repair and regeneration. Beginning with the biological and clinical foundations of wound healing, the book systematically examines inflammatory pathways and key biomarkers such as TNF-α, IL-6, ROS, and VEGF.It then advances into in-depth coverage of natural biopolymers—includin... collagen, chitosan, hyaluronic acid, silk-derived polymers, and marine polysaccharides—and their roles in immune modulation, macrophage polarization, and redox balance. Dedicated sections explore advanced delivery platforms such as nanofibers, smart hydrogels, nanozymes, and stimuli-responsive dressings, alongside emerging precision technologies including 3D printing and AI-guided material design. With a strong translational focus, the book bridges laboratory research and real-world application, addressing regulatory pathways, manufacturing scalability, and commercialization challenges.
  • Spaceflight Ophthalmology and Medicine

    A Comprehensive Guide to Ocular Health and Related Systemic Health Risks in Astronauts and Space Travelers
    • 1st Edition
    • Ryung Lee + 4 more
    • English
    Spaceflight Ophthalmology and Medicine: A Comprehensive Guide to Ocular Health and Related Systemic Health Risks in Astronauts and Space Travelers provides a comprehensive exploration of ocular health issues faced by astronauts during space missions. The book brings together contributions from leading experts in various fields, addressing the multifaceted risk factors associated with spaceflight and their implications for vision and overall health. Sections examine risk factors for ophthalmic diseases, including the effects of microgravity, space radiation, and oxidative stress, and explore innovative approaches in spaceflight ophthalmology, such as advanced diagnostic techniques and potential treatments for ocular conditions specific to the space environment. This book serves as an essential resource for researchers, clinicians, and space medicine professionals. By offering insights into the latest research and practical applications, it enhances understanding of ocular health in space and promotes the development of effective strategies to ensure astronaut safety and mission success.
  • Neonatal Surgery

    Techniques, Evidence and Outcomes
    • 1st Edition
    • David J. Hackam
    • English
    Neonatal Surgery: Techniques, Evidence, and Outcomes addresses the growing need for specialized surgical care in neonates, whose unique physiology demands distinct considerations from other surgical populations. Written by leaders in the field, this definitive textbook is the first devoted entirely to neonatal surgery, filling a vital gap in the literature with evidence-based guidance on timing, technique, and postoperative management for optimal outcomes. The book opens with the general care of the neonatal surgical patient, covering anatomy and physiology, preoperative workup, anesthesia, pain management, nursing, family experience, transport, nutrition, pharmacy, vascular access, and radiographic considerations. Subsequent sections address specialized areas including head and neck, thoracic, abdominal, urologic, orthopedic, neurosurgical, plastic and reconstructive, and congenital heart surgery, each offering detailed, evidence-based guidelines and techniques for managing specific conditions. The book concludes with a look at the future of neonatal surgery and considerations for surgery in low- and middle-income countries. An invaluable resource for clinical learners and practicing surgeons alike, it serves as a critical how-to guide for students and residents and an authoritative reference for practicing surgeons, including evidence-based management strategies. Researchers will find it indispensable for understanding the metabolic and physiological responses to neonatal surgery, adding translational relevance to their work. This textbook is essential for anyone involved in the surgical care of neonates, providing the knowledge needed to achieve the best possible outcomes
  • Legal Issues in Quality for Healthcare Institutions

    • 1st Edition
    • Ramesh Sachdeva
    • English
    Legal Issues in Quality for Healthcare Institutions provides the perspective of practicing physicians, lawyers, and academic legal scholars to comprehensively address the implications for quality of care and patient safety both from a legal, medical, and improvement science standpoint. Hospital administrators, physicians, nurses, researchers, legal scholars, as well as regulatory and compliance officers working in hospitals and acute care facilities will find this to be a helpful resource in understanding and addressing the many facets and issues in the field of medicine and law related to quality and patient safety.
  • Synthetic Biology in Medicine

    Tools and Transformative Therapies
    • 1st Edition
    • Xie Zhen
    • English
    Synthetic Biology in Medicine: Tools and Transformative Therapies covers the design and optimization of artificial biological components, gene editing systems, principles for designing and constructing artificial gene circuits, cell engineering, delivery systems of artificial biomolecules, and the prospects and challenges of synthetic biology technologies applied in drug development. The book contains many application cases related to clinical practice and industry, offering references for solving industrial pain points.
  • Urinary Incontinence

    Integrating Science and Clinical Practice
    • 1st Edition
    • Marcus Drake + 2 more
    • English
    Urinary Incontinence: Integrating Science and Clinical Practice succinctly describes the importance of lower urinary tract physiology to all for an understanding of urinary incontinence and its clinical treatment. World-leading contributors describe the key influences on mechanisms and therapies for proper understanding of the scientific basis of incontinence.The first part of the book is dedicated to System Physiology: Function and Adaptation. In this section, an anatomical sequence is followed for presenting the chapters, moving from the lower urinary tract organs upwards through the spinal centers to the brain. These chapters discuss what is known and unknown for crucial areas, such as neurological control and co-ordination, bladder fibrosis, bladder physiology and more.The second part is dedicated to Incontinence: Mechanism and Therapy. In this clinical application section, chapters derive from the clinical classification of incontinence and explore topics such as the role of urodynamics; mechanisms underpinning medical and interventional treatments; the sensations arising from the lower urinary tract; adverse effects of therapy and the considerable faced in managing incontinence.Written for researchers and clinicians, this book is a welcomed resource for those aiming to understand more about urinary incontinence.
  • Molecular Pathophysiological Basis of Lifestyle-Related Diseases

    Case Studies and Clinical Management
    • 1st Edition
    • Tetsuya Watanabe
    • English
    Molecular Pathophysiological Basis of Lifestyle-Related Diseases: Case Studies and Clinical Management presents an integrated molecular and biophysical account of lifestyle-related diseases, including type 2 diabetes, hypertension, atherosclerosis, chronic kidney disease, periodontitis, and neurodegenerative disorders. Rather than treating these conditions as isolated clinical entities, it examines their shared origins in chronic low-grade inflammation, oxidative stress, mitochondrial dysfunction, metabolic dysregulation, sympathetic overactivity, and psycho-emotional stress. Drawing on mathematical, physical, chemical, and molecular principles, the book explains how measurable pathological events emerge from disrupted tissue function and how these mechanisms shape clinical signs, disease progression, and patient management. Clinical case studies and management strategies connect mechanistic pathophysiology to real-world decision-making, making the volume useful for clinicians, researchers, and advanced students seeking a deeper understanding of prevention, diagnosis, and treatment. By bridging redox biology, neuroendocrine regulation, cardiovascular and renal physiology, and metabolic disease, the book offers a coherent framework for understanding the worldwide rise of lifestyle-related disorders and for developing more targeted clinical and research responses. Written for clinical doctors, medical researchers, pathophysiology scientists, biologists, and physicists in biomedical research or bioengineering.
  • Artificial Intelligence in Immunoengineering

    Methods, Models, and Translational Applications
    • 1st Edition
    • Steven Zanganeh + 1 more
    • English
    Artificial Intelligence in Immunoengineering: Methods, Models, and Translational Applications examines how AI reshapes immunoengineering to design immune-modulating biomaterials, imaging systems, and diagnostic tools. The book presents an integrated view of data-driven approaches that accelerate discovery and translation in biomedicine. It surveys biological data from single-cell to spatial omics and proteogenomics and offers practical machine learning frameworks, generative and mechanistic models, and multimodal integration strategies. Sections address bench-to-bedside translation, validation pipelines, and regulatory considerations for AI-enabled immunoengineering tools.The book highlights the rapid progress of multidisciplinary research within immunotherapy and immunoengineering. Looking forward, the prospects of immunoengineering appear promising, with further advancements in disease prevention, diagnostics, and treatment on the horizon. Graduate students, academic researchers, clinician-scientists... and computational biologists will gain standardized workflows, mechanism-aware modeling, and reproducible pipelines that advance immunotherapies and diagnostics from concept to clinical impact.
  • Critical Care in Pregnant Patients

    Ultrasound
    • 1st Edition
    • Jorge Hidalgo + 3 more
    • English
    Critical Care in Pregnant Patients: Ultrasound, a volume in the Critical Care Obstetrics series, is a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women with various health compromises. The book's chapters reflect the growing scope of critical care obstetrics and the increasing importance and recognition of the hospital structure's field. All intensivists, regardless of primary discipline, must possess a core set of critical care skills to manage critically ill patients. The book's authors have gathered the best evidence-based material explicitly focused on how ultrasound can successfully manage potential scenarios of common and rare health complications. Users will find the basics of ultrasound and the latest technological advances of ultrasound that foster research and improve health outcomes in pregnant patients.
  • Aging and Troponin

    Clinical Implications and Uses Beyond Diagnosis
    • 1st Edition
    • Gary Tse + 3 more
    • English
    Aging and Troponin: Clinical Implications and Uses Beyond Diagnosis examines the multifaceted role of troponin in clinical medicine, with a special focus on aging. This comprehensive reference provides essential technical knowledge, diagnostic and prognostic applications, and model development insights from leading experts in clinical biochemistry, pathology, and epidemiology. The book emphasizes the impact of aging on troponin test results and their interpretation, addressing age-related disorders such as renal failure. Sections cover the technical aspects of troponin assays, comparing traditional and high-sensitivity assays and exploring point-of-care testing advancements.The book also examine age-related changes and intra- and inter-individual variability in troponin levels, focuses on diagnostic applications, including troponin as a biomarker for cardiac injury and dysfunction, and the effects of age, sex, and renal impairment on diagnostic sensitivity and specificity, and discusses troponin's prognostic value for mortality in various conditions, including heart disease, sepsis, and COVID-19, and its role as a marker of organ biological age. The final section offers cutting-edge insights into the clinical applicability of troponin testing, highlighting the benefits of incorporating high-sensitivity assays into clinical workflows and providing perspectives and age-related considerations from practicing physicians on implementation and evidence-based practice.
  • Evidence Based Diagnosis and Management of Testicular Tumors

    • 1st Edition
    • Axel Heidenreich
    • English
    Evidence Based Diagnosis and Management of Testicular Tumors is a comprehensive reference that addresses the current needs of urologists, oncologists, and related specialists involved in testicular cancer care. This book synthesizes the latest research, clinical guidelines, and expert insights to facilitate accurate diagnosis, staging, and personalized treatment strategies. It emphasizes a multidisciplinary approach, integrating pathology, molecular genetics, imaging, and surgical techniques, to optimize patient outcomes and minimize long-term toxicity. The contents are organized into key sections covering epidemiology, pathology, staging, diagnostic evaluation, disease management, and follow-up. Each chapter begins with case scenarios and interactive questions, fostering active learning and decision-making skills. The book also dedicates sections to rare tumors and pediatric cases, ensuring broad applicability across age groups and tumor types. Visual content, including figures, flow charts, tables, and videos, enhances comprehension and procedural training. This reference aims to bridge the knowledge gap in current testicular cancer management, providing practitioners with practical, guideline-conforming advice. It supports clinicians in delivering individualized, risk-adapted care, ultimately improving survival rates and quality of life for patients. By combining expert perspectives with evidence-based protocols, this book serves as an essential resource for advancing clinical practice in testicular oncology.
  • Artificial Intelligence in Clinical Medicine

    General Concepts and Specific Applications
    • 1st Edition
    • Marianne Legato J. + 1 more
    • English
    Artificial Intelligence in Clinical Medicine: General Concepts and Specific Applications explores the evolution and application of artificial intelligence (AI) in medicine, highlighting both its potential and challenges. The initial discussion outlines past failures in integrating AI into healthcare, followed by a review of FDA-approved AI medical devices and their implications for diagnostics. Subsequent sections examine the transformative impact of large language models, the ethical application of AI in clinical settings, and the role of AI in enhancing patient safety. Various specialties, such as cardiology and pulmonary disease, illustrate AI's capabilities in improving diagnostics and treatment. The discussions extend to diabetes care, dermatology, obstetrics, and radiology, emphasizing the need for ethical considerations and quality assessments to ensure AI aligns with human values and improves patient outcomes across diverse healthcare contexts.
  • Molecular Pathology

    The Molecular Basis of Human Disease
    • 3rd Edition
    • Gregory J. Tsongalis + 1 more
    • English
    Molecular Pathology: The Molecular Basis of Human Disease, Third Edition is a comprehensive reference that explores the molecular mechanisms and basis of major human diseases. Expertly crafted, this book is designed for use as a teaching tool for medical students, biomedical graduate students, and allied health students. It serves as an advanced resource for pathology residents, postdoctoral fellows, basic scientists, and physician scientists engaged in disease-related research, presenting traditional pathology in the context of translational molecular medicine. In this new edition, the chapters have been fully updated and rearranged for better logical flow.Notably, four new chapters have been included, covering topics such as the pathogenesis of fibrotic diseases, mechanisms of mutation, molecular basis of soft tissue disease and pathology, and pathogenesis and pathophysiology. The book remains an invaluable reference for anyone seeking a deeper understanding of the molecular aspects of human disease.
  • Rational 'Co-Design' of Targeted Anticancer Therapeutics

    Integrating Immuno-Oncology, Biomaterials, and Translational Systems
    • 1st Edition
    • Y. Manojkumar + 3 more
    • English
    Rational 'Co-Design' of Targeted Anticancer Therapeutics: Integrating Immuno Oncology, Biomaterials, and Translational Systems presents a unified, system level framework that designs molecules, carriers, and delivery pathways concurrently for clinically translatable cancer therapies. The book details how electronic structure, molecular recognition, biomaterial compatibility, immune microenvironment dynamics, and ADMET/AI models integrate into end to end decision frameworks—from in silico prediction to experimental validation and regulatory readiness. Readers gain a pragmatic path to faster, safer translation: case informed guidance, co design checklists, and criteria for affordability, scalability, and sustainability enable researchers and advanced students to move beyond fragmented, sequential development toward robust therapeutic systems.
  • Pediatric Culinary Medicine

    Evidence, Opportunities, and Practice
    • 1st Edition
    • Maria R. Mascarenhas + 2 more
    • English
    Pediatric Culinary Medicine: Evidence, Opportunities, and Practice is a groundbreaking resource authored by diverse pediatric leaders, offering a comprehensive exploration of the rapidly evolving field of food as medicine. This book uncovers the history, benefits, and current research landscape, highlighting future opportunities for advancing pediatric health & development through culinary approaches. It provides practical insights into supporting children from diverse cultural and socioeconomic backgrounds, including those managing chronic conditions and those seeking to optimize wellness. Perfect for both newcomers and seasoned practitioners, this book will inspire innovative ways to integrate food into pediatric care. Packed with expert knowledge, this volume covers the evolution of culinary medicine, current research gaps, and practical strategies for real-world application in a pediatric setting. It features detailed chapters on dietary patterns that promote child health, culturally relevant practices, and policy opportunities, along with pathways for training and education, offering essential guidance for translating culinary medicine into meaningful, sustainable programs that improve pediatric health outcomes. Designed to serve a broad audience, Pediatric Culinary Medicine: Evidence, Opportunities, and Practice is an invaluable tool for researchers seeking to identify gaps and develop impactful studies and for pediatric healthcare providers aiming to implement evidence-based practices. It provides the foundational knowledge, successful models, and training resources needed to harness the power of food to transform child health. This book is a must-have for anyone committed to shaping the future of pediatric nutrition and wellness through culinary medicine.
  • Pediatric Gastroenterological Diagnosis

    A Diagnostic Primer
    • 1st Edition
    • Richard Thomas Lee Couper
    • English
    Pediatric Gastroenterological Diagnosis: A Diagnostic Primer focuses on the theoretical aspects of diagnosing pediatric gastroenterology diseases, including historical and current information. Sections cover pediatric gastroenterology diseases and provide practical advice for quick and accurate diagnosis. In addition, the book provides multiple pediatric tables and references, as well as brief clinical vignettes that identify potential pitfalls clinicians may encounter. This is the perfect reference for clinicians who struggle with complex diagnosis and problem-solving, and will be ideal for pediatric gastroenterology trainees and pediatric gastroenterologists.
  • Precision Care in Gastroesophageal Reflux Disease

    Using Pathophysiology and Clinical Insights towards a Personalized Approach
    • 1st Edition
    • Walter W. Chan + 1 more
    • English
    Precision Care in Gastroesophageal Reflux Disease: Using Pathophysiology and Clinical Insights towards a Personalized Approach addresses the urgent need for personalized approaches in managing GERD. This reference explores the evolving understanding of GERD pathophysiology and the necessity to move beyond generalized treatments toward disease phenotyping and targeted therapy. It emphasizes integrating clinical insights with emerging diagnostic technologies to optimize patient outcomes. The book’s content is organized into sections covering disease phenotypes and pathophysiology, clinical presentation, diagnostic techniques, and management approaches. Chapters include detailed discussions on symptom mechanisms, hypervigilance, diagnostic endoscopy, esophageal function testing, and both medical and surgical treatment options. Contributions from international experts provide evidence-based perspectives on utilizing scoring systems, ancillary tests, and adjunctive therapies to support precision care. Precision Care in Gastroesophageal Reflux Disease equips clinicians, advanced practice providers, and trainees with state-of-the-art knowledge to tailor evaluation and treatment strategies for diverse GERD phenotypes. It is an essential resource for those seeking to apply precision medicine principles in gastroenterology, enhancing diagnostic accuracy and therapeutic effectiveness in clinical practice.
  • Rare and Complex Liver Diseases

    • 1st Edition
    • Ansgar Wilhelm Lohse + 2 more
    • English
    Rare and Complex Liver Diseases is a comprehensive guide that fills a critical gap in the literature, providing up-to-date, practical advice. The book is organized into distinct sections, each dedicated to a specific category of liver diseases. Topics covered include Autoimmune Liver Diseases such as Autoimmune Hepatitis (AIH) and Primary Biliary Cholangitis (PBC); Cholestatic Liver Diseases including Biliary Atresia and Alagille Syndrome; Vascular Liver Diseases like Budd-Chiari Syndrome and Non-cirrhotic Portal Hypertension; Metabolic Liver Diseases such as Wilson Disease and Alpha-1 Antitrypsin Deficiency; Structural Liver Diseases including Polycystic Liver Disease; and Rare Liver Tumors like Cholangiocarcinoma and Hemangioendothelioma... chapters cover Liver Disease in Pregnancy and delve into Quality of Life issues, offering evidence-based insights and practical strategies for improving patient well-being. This book serves as an indispensable resource for gastroenterologists, hepatologists, internists, and researchers specializing in liver diseases. It equips these professionals with the knowledge and practical advice necessary to improve patient outcomes and advance their field of study.
  • Coronary Physiology in the Cardiac Cath Lab

    • 1st Edition
    • William F. Fearon
    • English
    Coronary Physiology in the Cardiac Cath Lab provides the foundational knowledge required to understand the concepts behind a variety of coronary physiologic assessments performed and required to apply them effectively when evaluating cardiac patients. Written to bring a practical and evidence-based approach, this book is a valuable resource for interventional and general cardiologists, cardiology researchers, physicians, cardiac catheterization laboratory staff, and anyone interested in understanding the theory and current practice surrounding assessing coronary physiology in the cardiac cath lab.Over the past decade, there has been an explosion of data validating the importance of assessing coronary physiology at the time of coronary angiography. This has led to the development of numerous new techniques and metrics for performing these assessments and also resulted in the inclusion of these indices into practice guidelines.