Books in Life sciences general

Aortic Valve Repair

1st Edition
February 2, 2026
J Scott Rankin
English
Paperback
9 7 8 0 1 2 8 2 3 0 2 5 1
eBook
9 7 8 0 1 2 8 2 3 0 5 4 1

Aortic Valve Repair provides a comprehensive summary on techniques developed during the first 500 cases of aortic ring annuloplasty. Aortic valve disease is usually surgically managed by aortic valve replacement, and it is well established in published literature regarding the long-term results, survival rate, durability of the protheses and reoperations rates. Over the past two decades, aortic valve repair (AVr) has evolved into a recognized surgical option for selected patients with aortic insufficiency or proximal aorta aneurysm. Studying the first 500 cases of aortic ring annuloplasty, the authors provide the most effective methods of leaflet and aortic root reconstruction to repair pathologies.Includin... original illustrations and videos, the book serves as an essential reference for cardiac surgeons in practice.

Glial Mechanisms in Sleep and Circadian Biology

1st Edition
February 2, 2026
Marcos G. Frank
English

Glial Mechanisms in Sleep and Circadian Biology presents a comprehensive and up-to-date discussion of the role of glial cells in numerous, often unexpected, aspects of sleep. It seamlessly links glial cell activity to the multi-system processes that affect sleep. Experts in the field discuss how glial cells influence the sleep-wake cycle, the accumulation and discharge of sleep drive, the timing of sleep and wake across the 24-hour day, and how glial cells may govern important sleep functions (e.g., brain plasticity and metabolism). This is a book that could well change scientists’ and practitioners’ traditional beliefs about the factors underlying sleep.Users will find the book's content at the forefront of one of the hottest topics in basic sleep research. Over the last decade, scientists have made breakthrough discoveries revealing that sleep is not only a product of neurons, but of neuronal-glial interactions.

Geriatric Neurosurgery in Clinical Practice

1st Edition
February 2, 2026
English

Geriatric Neurosurgery: An Evidence-Based Approach is an essential resource that provides a thorough and modern overview of geriatric neurosurgery. This volume compiles the latest research and clinical practice guidelines, offering practical advice for clinicians caring for elderly patients. It delves into a range of topics, including the management of common neurosurgical conditions in elderly patients, surgical techniques, postoperative care, and the integration of multidisciplinary approaches to enhance patient outcomes. Users will find this to be an invaluable reference for practicing neurosurgeons, neurosurgery residents, neurologists, geriatric physicians, and researchers seeking clear and concise information on current treatments and procedures for geriatric neurosurgery.

Fluid Dynamics of Viral Transmission

1st Edition
February 2, 2026
Mehrzad Shams + 1 more
English

Fluid Dynamics of Viral Transmission is an essential exploration into the transmission dynamics of COVID-19, focusing specifically on the airborne spread of respiratory aerosols carrying infectious viruses. In light of the recent global pandemic, it offers crucial insights into the complex interaction between fluid dynamics and viral transmission and provides practical solutions for minimizing risks in indoor environments. The book delves into CFD simulations, optimizing ventilation systems, air filtration strategies, and spatial layout modifications. It evaluates mitigation measures such as mask-wearing, physical distancing, and occupancy limits, aiming to equip readers with the knowledge to create safer indoor spaces. This book is ideal for public health officials, policymakers, healthcare professionals, engineers, researchers, and academics in fluid mechanics, computational fluid dynamics, epidemiology, and virology.

Translational Cardiothoracic Surgery

1st Edition
February 1, 2026
Adam E.M. Eltorai + 4 more
English

Translational research is essential to the advancement of medicine. This Cardiothoracic-speci... instructional guide to translational medical research serves as a practical, step-by-step roadmap for taking a biomedical device, potential therapeutic agent, or research question from idea through demonstrated clinical benefit. Fundamentally, the volume aims to help bridge the gap between current research and practice. Written by a team of expert medical, biomedical engineering, and clinical research experts in cardiothoracic surgery, this volume provides a clear process for understanding, designing, executing, and analyzing clinical and translational research within the field.

Biomedical Basis of Human Disease

1st Edition
February 1, 2026
Ahmed El-Hashash + 2 more
English
Hardback
9 7 8 0 3 2 3 9 9 8 7 0 3
eBook
9 7 8 0 3 2 3 9 8 5 0 9 3

Biomedical Basis of Human Disease: From Research to Clinic provides information on pathophysiology/mech... of organ system disease and selected disorders and diseases that cause the most deaths worldwide, including but not limited to cardiovascular, respiratory, gastrointestinal and nervous systems. This information is placed within the structural context of tissue/organ, molecular and cellular biology, pathophysiology, diagnostic and treatment methods, and disease models in sections that also describe recent research examples, such as recently developed cutting-edge in vitro and in vivo biomedical science methods to bridge the bench and bedside. This text is suitable for students, researchers and practitioners in biomedicine and basic medicine.

Intelligent Osteogenesis

1st Edition
February 1, 2026
Carlo Galli
English

Intelligent Osteogenesis: How A.I., New Materials, and Manufacturing Technologies are Reshaping Bone Regeneration delves into the revolutionary intersection of technology and medicine. The book focuses on how cutting-edge advancements like artificial intelligence, nanotechnology, biotechnology, and material science significantly influence and transform bone regeneration therapies. It aims to shed light on the multifaceted nature of this field, bringing diverse elements together to reveal their collective impact. The book covers the use of A.I. to monitor advancements, the acceleration of research, and the technological influence on the application of bone regenerative techniques.Authored by experts, it serves as a definitive guide for both biomedical researchers and clinical practitioners in dentistry and orthopedics.

Reverse Aging

1st Edition
February 1, 2026
Sandeep Kumar Singh + 1 more
English

Reverse Aging: Current Research and Future Directions explores the integrated approach of aging and reverse aging to present a comprehensive understanding of the biological, genetic, and molecular mechanisms associated with aging. By targeting fundamental aging mechanisms, strategies are being developed to reverse and repair damage and potentially lead to greater healthspan benefits and optimal longevity. The book opens with the fundamentals of aging and how genetic, environmental, and lifestyle variables affect the biological, psychological, and social processes that lead to aging before delving into a comprehensive review of the hallmarks of aging. Next, an overview of the concept of reverse aging is presented, and subsequent chapters examine specific reverse aging models and approaches. The book explores use of cellular reprogramming techniques, provides an overview of the molecular processes that underlie NANOG-mediated reversal aging, and discusses the possible contribution of IGF-1/PKA signaling reduction to reverse aging via HSC-based therapies. The developing science of rejuvenating stems cells, histone modification, and stimulation of autophagic activity to facilitate the removal of cellular debris and reduce the impact of aging on various organ systems as well as novel concepts of mRNA enhanced cell therapy, immunological-driven signaling, mitochondrial modulations, cell-cycle regulation, and metabolic reprogramming for reserve aging are all examined. The wide range of nutritional therapies, phytochemical, prescription medications, and nutraceuticals impacting the aging process is reviewed, and the book closes with discussion of the revolutionary role AI has on anti-aging research and where the field is headed. In conclusion, the book emphasizes the importance of targeting fundamental aging mechanisms to extend health and achieve optimal longevity and provides insights into the potential implications for healthcare and aging research, highlighting the need for collaborative efforts and interdisciplinary perspectives to address the challenges of population aging and develop effective strategies for healthy aging practices.

Advancing Liver Transplantation

1st Edition
February 1, 2026
Andrea Schlegel
English

Advancing Liver Transplantation: A Foundational Exploration of Machine Perfusion Techniques lays the groundwork for understanding the intricate world of liver transplantation within this groundbreaking reference book. Crafted with intuitive pedagogy and accessible formats, this reference serves as an entry point for students and entry-level practitioners, guiding them through fundamental concepts, processes, and applications in machine perfusion technology. From historical milestones to emerging innovations, the book provides a clear and comprehensive overview, ensuring readers quickly grasp essential knowledge to navigate this complex field. The meticulously structured table of contents acts as a roadmap, guiding readers through each section with ease. Starting with an introduction by editor Andrea Schlegel, the book explores historical perspectives and underlying mechanisms in Section 1, providing a solid foundation for further exploration. Contents dive into different machine perfusion techniques in Section 2, then navigate the practical aspects of implementation in clinical practice in Section 3. Finally, the book uncovers the latest innovations and emerging strategies in Section 4, consolidating understanding and building new connections along the way. Tailored for students, researchers, and practitioners across their career journey, this book caters to a diverse audience seeking to gain a solid foundation in liver transplantation and machine perfusion. Whether just starting an exploration or looking to refresh knowledge, this accessible and comprehensive coverage ensures the tools and insights needed to succeed in this dynamic field.

Insights into Direct-Acting Antivirals

1st Edition
February 1, 2026
Mohamed Mahmoud Zakaria El-Kassas
English

Insights Into Direct-Acting Antivirals: Mechanistic Impact on Chronic Hepatitis C is a comprehensive reference that explores Chronic Hepatitis C management. This authoritative reference covers the mechanisms, efficacy, and future potential of Direct-Acting Antivirals (DAAs), offering valuable insights for clinicians, researchers, and students in hepatology and infectious diseases. Structured into three sections, this reference covers a wide range of topics related to DAAs in the management of Hepatitis C. In Section 1, readers will gain a thorough understanding of HCV infection, its clinical significance, and the immune response involved. They will also explore the molecular mechanisms of DAAs and the different classes available. Section 2 focuses on the practical aspects of using DAAs in the treatment of HCV. Readers will discover the clinical efficacy of different DAA regimens, the safety and tolerability considerations, and the additional benefits of DAA treatment beyond virological response. The section also covers current treatment guidelines and individualized approaches for specific patient populations. In Section 3, readers will learn the challenges and future directions in DAA therapy including antiviral resistance in HCV and strategies for managing and overcoming resistance. The book also explores the relationship between DAA therapy and hepatocellular carcinoma, as well as the current limitations and unmet needs in DAA therapy. "Insights Into Direct-Acting Antivirals: Mechanistic Impact on Chronic Hepatitis C" is a comprehensive and indispensable resource for anyone involved in the management of Chronic Hepatitis C. With its in-depth exploration of DAAs, from their molecular mechanisms to their clinical applications and future directions, this book equips clinicians, researchers, and students with the knowledge and insights needed to enhance their practices and contribute to the global fight against HCV infection.

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