Quick Guide to Hemostasis and Transfusion Medicine
- 1st Edition - June 1, 2026
- Imprint: Elsevier
- Authors: George A. Fritsma, Rance Chadwick Siniard, Brianna Miller, Lance A. Williams III
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 3 7 8 0 - 8
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 3 7 8 1 - 5
Quick Guide to Hemostasis and Transfusion Medicine is a patient reference that recommends indication-based laboratory test selection and interpretation to diagnose and treat hemorr… Read more
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Quick Guide to Hemostasis and Transfusion Medicine is a patient reference that recommends indication-based laboratory test selection and interpretation to diagnose and treat hemorrhagic and thrombotic disorders using blood components, biologics, and synthetic therapeutics. The book introduces hemostasis and transfusion medicine for students, residents, and fellows, supplementing standard texts. It uses headings, bulletpoints, telegraphic syntax, tables, figures, and speedy lookup features and is an essential quick reference for health care providers who order, perform, and interpret hemostasis and immunohematology assays and administer hemostasis therapy.
- Presents a great resource for practical guidance that condenses hemostasis physiology and pathology, providing speedy, often lifesaving patient management
- Addresses the challenging issues that laboratory professionals face day to day
- Provides straightforward and timely recommendations for the selection and management of biological components
Medical laboratory technicians, medical laboratory scientists, people with academic and professional doctorates in medical laboratory science, clinical pathologists, and students, residents, and fellows in clinical pathology, hematology and most other specialties in medicine, anyone involved in laboratory assay utilization, performance, and interpretation for the purpose of diagnosis and treatment, Laboratory directors of clinical testing laboratories, staff responsible for validating clinical tests and maintaining a quality program
1. Approach to bleeding patients
a. Patient history, bleeding assessment test protocol
b. Acquired versus congenital, isolated versus coagulopathy, systemic versus anatomic
2. Approach to thrombosis patient
a. Patient history
b. Acquired versus congenital thrombosis
c. Arterial versus venous thrombosis
3. Blood specimen management
4. Test utilization and indications
5. Antithrombotic therapy
a. Oral anticoagulants: warfarin and DOACs
b. Parenteral anticoagulants: heparin types
c. Direct thrombin inhibitors
d. Antiplatelet therapeutics
6. Platelets
a. Normal platelet function
b. Platelet disorders: thrombocytopenia and functional disorders
c. Immune and thrombotic thrombocytopenic purpura
d. Platelet function testing
e. Viscoelastometry
7. Coagulation
a. Normal coagulation cascade
b. Clot-based and chromogenic testing
8. Bleeding disorders: diagnosis and management
a. Acquired coagulopathies: liver disease, dietary deficiencies, kidney disease
b. Trauma-induced coagulopathy
c. Hemophilia: congenital single factor deficiencies
d. Von Willebrand disease
e. Disseminated intravascular coagulation
f. Laboratory protocols
g. Viscoelastometry
9. Thrombophilia
a. Congenital thrombosis risk factors
b. Antiphospholipid syndrome
c. Heparin-induced thrombocytopenia with thrombosis
d. Thromboinflammation
e. Laboratory protocols
10. Transfusion safety
11. Blood donation, processing, management
a. Donor qualification, whole blood, plateletpheresis, plasmapheresis
b. Directed donations
12. Blood components: Red blood cells, leukocyte-reduction, CMV-negative products, irradiated products, plasma, cryoprecipitate, platelet concentrate, whole blood, coagulation factor concentrates
13. Patient blood management: medical transfusion decisions, transfusion refusal
a. Urgent blood need, group O whole blood
b. Massive transfusion protocol
c. Transfusion of neonates and neonatal immune thrombocytopenia
d. Platelet concentrates
e. Transfusion in autoimmune hemolytic anemia, sickle cell disease, IgA deficiency, etc
f. Progenitor cell transplant
14. Managing adverse transfusion effects: signs and symptoms—immediate and delayed, laboratory investigation, care
15. Therapeutic apheresis: indications, types, technical and clinical considerations
16. Features
a. Glossary and abbreviations
b. Table of tables
c. Table of figures
d. Table of equations
e. Reference intervals and therapeutic targets
f. Index
g. References
a. Patient history, bleeding assessment test protocol
b. Acquired versus congenital, isolated versus coagulopathy, systemic versus anatomic
2. Approach to thrombosis patient
a. Patient history
b. Acquired versus congenital thrombosis
c. Arterial versus venous thrombosis
3. Blood specimen management
4. Test utilization and indications
5. Antithrombotic therapy
a. Oral anticoagulants: warfarin and DOACs
b. Parenteral anticoagulants: heparin types
c. Direct thrombin inhibitors
d. Antiplatelet therapeutics
6. Platelets
a. Normal platelet function
b. Platelet disorders: thrombocytopenia and functional disorders
c. Immune and thrombotic thrombocytopenic purpura
d. Platelet function testing
e. Viscoelastometry
7. Coagulation
a. Normal coagulation cascade
b. Clot-based and chromogenic testing
8. Bleeding disorders: diagnosis and management
a. Acquired coagulopathies: liver disease, dietary deficiencies, kidney disease
b. Trauma-induced coagulopathy
c. Hemophilia: congenital single factor deficiencies
d. Von Willebrand disease
e. Disseminated intravascular coagulation
f. Laboratory protocols
g. Viscoelastometry
9. Thrombophilia
a. Congenital thrombosis risk factors
b. Antiphospholipid syndrome
c. Heparin-induced thrombocytopenia with thrombosis
d. Thromboinflammation
e. Laboratory protocols
10. Transfusion safety
11. Blood donation, processing, management
a. Donor qualification, whole blood, plateletpheresis, plasmapheresis
b. Directed donations
12. Blood components: Red blood cells, leukocyte-reduction, CMV-negative products, irradiated products, plasma, cryoprecipitate, platelet concentrate, whole blood, coagulation factor concentrates
13. Patient blood management: medical transfusion decisions, transfusion refusal
a. Urgent blood need, group O whole blood
b. Massive transfusion protocol
c. Transfusion of neonates and neonatal immune thrombocytopenia
d. Platelet concentrates
e. Transfusion in autoimmune hemolytic anemia, sickle cell disease, IgA deficiency, etc
f. Progenitor cell transplant
14. Managing adverse transfusion effects: signs and symptoms—immediate and delayed, laboratory investigation, care
15. Therapeutic apheresis: indications, types, technical and clinical considerations
16. Features
a. Glossary and abbreviations
b. Table of tables
c. Table of figures
d. Table of equations
e. Reference intervals and therapeutic targets
f. Index
g. References
- Edition: 1
- Published: June 1, 2026
- Imprint: Elsevier
- Language: English
GF
George A. Fritsma
Dr. George Fritsma manages www.fritsmafactor.com, “The Fritsma Factor, Your Interactive Hemostasis Resource,” an educational blog supported by Precision BioLogic Inc, Dartmouth, Nova Scotia. Dr. Fritsma also consults for the Laboratory Solutions Program for Developing Nations, supported by BioMedica Diagnostics, Inc., Windsor, Nova Scotia. He is a consultant for the Laboratory Medicine Division of the Pathology Department, University of Alabama at Birmingham School of Medicine, where he provides lectures for pathology residents and for hematology fellows. He is an adjunct Associate Professor for Michigan State and Rutgers University.
George chairs the American Association for Clinical Chemistry Press Board and is a consulting editor for the Clinical Laboratory Science journal and is a member of the International Society on Thrombosis and Hemostasis and the International Society for Laboratory Hematology.
Affiliations and expertise
Clinical Associate Professor, Pathology, Division of Laboratory Medicine, School of Medicine University of Alabama at Birmingham, USARS
Rance Chadwick Siniard
Dr. Rance Chadwick Siniard is an Assistant Professor in Department of Pathology and Laboratory Medicine at the University of Alabama at Birmingham. He is the Director of Community Practice Pathology Program Transfusion Medicine and Director of Coagulation Laboratory, Laboratory Medicine, Clinical Pathology. His research interest is in hemostasis and thrombosis research.
Affiliations and expertise
Assistant Professor Department of Pathology and Laboratory Medicine, University of Alabama at Birmingham, USABM
Brianna Miller
Brianna Miller is an Assistant Professor in the Medical Laboratory Sciences program at the University of Alabama at Birmingham. She holds a Master’s degree in Clinical Laboratory Science and an advanced certification as a Specialist in Blood Banking. After beginning her career at UAB Hospital in the Transfusion Medicine Service as a Medical Laboratory Scientist, she quickly moved into the position of Antibody Specialist. Eventually, she shifted to the academic side of UAB, advancing to an Assistant Professor. Mrs. Miller’s main disciplines of teaching include Transfusion Medicine and Hemostasis, but she also teaches various subjects in laboratory medicine to students in programs of Physician Assistants, Physical Therapy, Optometry, Biomedical Sciences, and Clinical Pathology Residents.
Affiliations and expertise
Assistant Professor, Medical Laboratory Sciences program, University of Alabama, Birmingham, USALW
Lance A. Williams III
Dr. Williams is currently an Assistant Professor in the Department of Pathology, Division of Laboratory Medicine and serves as the Medical Director of Hemostasis Laboratory at the University of Alabama at Birmingham. He is also the Director of Transfusion Medicine for the Community Pathology Practice Program, which encompasses 5 hospitals throughout Alabama. Dr. Williams received his BS with high honors in Biology from Longwood University and his MD with honors from Ross University. He completed residency training at East Carolina University and two fellowships – Transfusion Medicine at Yale University and Hematopathology at Virginia Commonwealth University. Dr. Williams is an award-winning teacher, known for his innovative teaching methods and his dedication to elevating students of all levels. His publications include original research articles, review articles, and books, including Quick Guide to Transfusion Medicine, 2nd edition. Nationally, he is known as an engaging and knowledgeable speaker and he serves on many committees committed to advancing the science of Transfusion Medicine, Apheresis, and Hemostasis.
Affiliations and expertise
MD, Department of Pathology, University of Alabama at Birmingham, AL, USA