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T Cell Metabolism and Cancer Immunotherapy

  • 1st Edition - September 1, 2024
  • Editor: Jianxun Song
  • Language: English
  • Hardback ISBN:
    9 7 8 - 0 - 4 4 3 - 1 3 8 2 7 - 0
  • eBook ISBN:
    9 7 8 - 0 - 4 4 3 - 1 3 8 2 8 - 7

T Cell Metabolism and Cancer Immunotherapy investigates the cellular regulation of T-cell immunity and tolerance. Within ten chapters, the content not only reveals targets o… Read more

T Cell Metabolism and Cancer Immunotherapy

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T Cell Metabolism and Cancer Immunotherapy investigates the cellular regulation of T-cell immunity and tolerance. Within ten chapters, the content not only reveals targets of T cell metabolism as critical determinants of immune regulation, but also uncovers unique therapeutic opportunities to improve immunotherapy through targeting T cell metabolism. This fills a significant gap in the knowledge of scientists working in the field of onco-immunology/immunotherapy, and students learning about T cells, metabolism, immunomodulation, and immunotherapy.

Because of the plasticity and potentially unlimited capacity for self-renewal, stem cell-derived T lymphocytes have great potential in the treatment of diseases, including cancer. Despite great advancement in immunotherapy, such as adoptive T cell transfer-based regimen, the clinical outcomes remain less satisfactory due to a variety of factors that lessen its therapeutic efficacy.