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T Cell Metabolism and Cancer Immunotherapy
- 1st Edition - September 1, 2024
- Editor: Jianxun Song
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 3 8 2 7 - 0
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 3 8 2 8 - 7
T Cell Metabolism and Cancer Immunotherapy investigates the cellular regulation of T-cell immunity and tolerance. Within ten chapters, the content not only reveals targets o… Read more
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Request a sales quoteT Cell Metabolism and Cancer Immunotherapy investigates the cellular regulation of T-cell immunity and tolerance. Within ten chapters, the content not only reveals targets of T cell metabolism as critical determinants of immune regulation, but also uncovers unique therapeutic opportunities to improve immunotherapy through targeting T cell metabolism. This fills a significant gap in the knowledge of scientists working in the field of onco-immunology/immunotherapy, and students learning about T cells, metabolism, immunomodulation, and immunotherapy.
Because of the plasticity and potentially unlimited capacity for self-renewal, stem cell-derived T lymphocytes have great potential in the treatment of diseases, including cancer. Despite great advancement in immunotherapy, such as adoptive T cell transfer-based regimen, the clinical outcomes remain less satisfactory due to a variety of factors that lessen its therapeutic efficacy.
- Provides a summary of the current state-of-the-art, creating a valuable foundation for both established researchers and newcomers/students in the field of cancer immunotherapies
- Focuses on the investigation of cellular regulation of T-cell immunity and tolerance
- Defines the precise role and mechanism of T cell metabolism in modulating T cells and T cell-mediated immunity
- Presents insights to develop and optimize strategies for utilizing highly reactive T lymphocytes for cell-based therapies
Cancer researchers, medical oncologists, clinicians, pharmacologists, translational investigators, buyer, library, Undergraduate and postgraduate courses in medicine, pharmacy, nursing, and related discipline
1. The role of T Cell Metabolism in Cancer Immunotherapies
2. Pancreatic cancer immunotherapy using childhood vaccine recall antigens and Listeria
3. Targeting MyD88 costimulation in cancer immunotherapy
4. T cell-derived IL-27 for cancer immunotherapy
5. Defeating cancer with immunomodulatory bacterial therapeutics
6. Salmonella-based cancer immunotherapy: current progress and prospects
7. Cancer immunotherapy for hepatocellular carcinoma
8. Integrative targeted therapy for melanoma
9. Controls of memory T cell differentiation
10. Inhibition of the Wnt/β-Catenin Pathway overcomes prostate cancer resistance
2. Pancreatic cancer immunotherapy using childhood vaccine recall antigens and Listeria
3. Targeting MyD88 costimulation in cancer immunotherapy
4. T cell-derived IL-27 for cancer immunotherapy
5. Defeating cancer with immunomodulatory bacterial therapeutics
6. Salmonella-based cancer immunotherapy: current progress and prospects
7. Cancer immunotherapy for hepatocellular carcinoma
8. Integrative targeted therapy for melanoma
9. Controls of memory T cell differentiation
10. Inhibition of the Wnt/β-Catenin Pathway overcomes prostate cancer resistance
- No. of pages: 220
- Language: English
- Edition: 1
- Published: September 1, 2024
- Imprint: Academic Press
- Hardback ISBN: 9780443138270
- eBook ISBN: 9780443138287
JS
Jianxun Song
Dr. Song is Professor of Microbial Pathogenies and Immunology at Texas A&M University Health Science Center, Bryan, TX
Is highly motivated to pursue an academic research career in Microbial Pathogenesis and Immunology. The base of expertise on T cell biology needed to perform the proposed research began to develop while he was a postdoctoral scholar and research scientist from the years 2000-2007 under the mentorship of Dr. Michael Croft at La Jolla Institute for Allergy & Immunology. As a PI on previous university-, foundation- and NIH-funded grants, he laid the groundwork for the proposed research by developing antigen-specific T lymphocytes from pluripotent stem cells.. He offered leadership and administrative skills that were developed during his independence as a mentor of graduate students and postdoctoral scholars.
Affiliations and expertise
Professor of Microbial Pathogenies and Immunology,Texas A&M University Health Science Center