Nutrition in the Control of Inflammation

Emerging Roles for the Microbiome and Epigenome

1st Edition - July 1, 2024
Editors: Bradley S. Ferguson, Steven Frese
Language: English
Paperback ISBN:
9 7 8 - 0 - 4 4 3 - 1 8 9 7 9 - 1
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 1 8 9 8 0 - 7

Nutrition in the Control of Inflammation: Emerging Roles for the Microbiome and Epigenome offers a comprehensive overview on how our diet promotes or attenuates inflammat… Read more

Purchase options

Limited Offer

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code needed.

Institutional subscription on ScienceDirect

Request a sales quote

Nutrition in the Control of Inflammation: Emerging Roles for the Microbiome and Epigenome offers a comprehensive overview on how our diet promotes or attenuates inflammation to regulate inflammatory diseases. Broken into five sections, this book presents an introduction to the microbiome and epigenome in nutrition, subsequently covering diet, lifestyle, and the microbiome in the development of inflammatory diseases, nutrition and the epigenome in metabolic and cardiovascular diseases, diet, epigenetics, and microbiome. The book also addresses health-disparities in diet, epigenetics and gut microbes.

This reference will be of interest to nutrition researchers, nutritionists, and postgraduate students, as well as others working in, studying, and researching related fields.

Section I. Introduction

1. Introduction: Nutrition, the microbiome, and the epigenome in human health and disease

Section II. Diet, lifestyle and the microbiome in development and inflammatory diseases

2. The microbiome across the lifecycle

3. The microbiome in infant gut health and development

4. The microbiome in early life as a risk factor for autoimmune diseases

5. The microbiome in gut inflammation and carcinogenesis

6. Obesity and the microbiome: A role for microbes in insulin resistance

7. Fiber and the gut microbiome and its impact on inflammation

8. Diet-specific impacts on the gut microbiome and their relation to health and inflammation

9. Hypertension, Obesity, and the microbiome in cardiovascular disease

10. Bariatric surgery, gut microbes, and metabolic health

11. Caloric restriction in the microbial regulation of inflammaging

12. Exercise, the gut microbiome and inflammatory disease

Section III. Nutrition and the epigenome in metabolic and cardiovascular diseases

13. Obesity, histone acetylation and insulin resistance

14. Obesity, DNA methylation and metabolic disease

15. Diet, histone modifications and cardiovascular diseases

16. Diet, DNA methylation and cardiovascular diseases

17. Obesity and non-coding RNAs in epigenetic inheritance of metabolic disease

18. Caloric restriction in the epigenetic regulation of aging and longevity

19. Exercise in epigenetic programing throughout life

Section IV. Diet, epigenetics, and the microbiome in inflammatory disease

20. Gut microbiome, epigenetics and neuro-inflammatory disease

21. Caloric restriction, gut microbes, epigenetics and inflammaging

22. Obesity, gut bacteria and the epigenetic control of metabolic disease

23. The microbiome-epigenome axis in infant gut health and development

24. The microbiome and epigenome intersect to regulate gut inflammation

Section V. Conclusions: Health-disparities in diet, epigenetics and gut microbes

25. Race, gender and ethnicity in the control of our gut microbes

26. The role for social-environmental influences in epigenetic determination

27. Practical applications for diet and lifestyle to improve microbial and epigenetic health

Bradley S. Ferguson

Dr. Bradley Ferguson is Assistant Professor of Nutrition at the University of Nevada, Reno, NV. His lab adopts integrative, translational research approaches that encompass bioinformatics, in vitro cell culture, and in vivo animal models to elucidate dietary food components that act as epigenetic modifiers, as well as the role of dietary epigenetic modifiers on pathological cardiac signaling, gene expression, and remodeling. He also seeks to understand how acetylation and deacetylation links metabolic disease (obesity and diabetes) to pathological cardiac remodeling and dysfunction. Dr. Ferguson has published his findings across a wide range of peer reviewed journals, including Scientific Reports, Journal of Animal Science, Current Pharmaceutical Design, and the Journal of Molecular and Cellular Cardiology.

Affiliations and expertise

Assistant Professor of Nutrition, University of Nevada, Reno, NV, USA

Steven Frese

Dr. Steven Frese is Assistant Professor of Nutrition at the University of Nevada, Reno, NV and holds an appointment as an Adjunct Assistant Professor at the Department of Food Science and Technology at the University of Nebraska, Lincoln. His research applies principles of microbial ecology and evolutionary biology to develop rational interventions to improve human health via the gut microbiome. This includes applying advanced techniques including bioinformatics, DNA/RNA sequencing, and mass spectrometry to determine strain- and ecosystem-level interactions both in vitro and in human clinical trials. His work has primarily focused on the gut microbiome in early life, and the role of diet and the microbiome in shaping infant health and development. Dr. Frese’s work has been published in a variety of broad interest peer-reviewed journals including Cell, Science Translational Medicine, Cell Host & Microbe, and PLoS Genetics, as well as audience specific journals including Pediatric Research, Glycobiology, and Bioinformatics

Affiliations and expertise

Assistant Professor, University of Nevada, USA