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Elsevier

Books in Organic chemistry

This collection offers extensive coverage of organic synthesis, reaction mechanisms, and functional group chemistry. Showcasing innovative research, green chemistry approaches, and industrial applications, it supports chemists, students, and researchers in designing new molecules and materials. Addressing drug discovery, polymers, and sustainable processes, these titles foster creativity and technical excellence in advancing organic chemistry for societal benefit.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 150
    • English
    Advances in Heterocyclic Chemistry, Volume 150 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics such as Hetero-antiaromatics... 1,3,2,4-benzodithiad... and related compounds, The Synthesis and Properties of Heterocyclic Derivatives of Steroids, Advances in the Chemistry and Applications of Isothiazoles fused with other heterocycles, 3(5)-Amino-1,2,4-tri... versatile synthons for triazole-based fused heterocycles, Photocatalytic Decarboxylative Alkylation: A Mild Strategy for Heterocycle Functionalization, and The Influence of Sulfones on the Synthesis and Properties of Heterocycles.

  • Photonic Sensors for Detection of VOC Biomarkers

    Technological Principles and Medical Applications
    • 1st Edition
    • Sridhar Krishnaswamy + 2 more
    • English
    VOCs available in exhaled human breath are the products of metabolic activity in the body and, therefore, any changes in their control level can be utilized to diagnose specific diseases. More than 1000 VOCs have been identified in exhaled human breath along with the respiratory droplets which provide rich information on overall health conditions. Photonic Sensors for Detection of VOC Biomarkers: Technological Principles and Medical Applications cover the introductory information on VOCs, their source in the human body, associated diseases, potential sensing materials used for selective detection, and the advancement in their sensing technology. These VOCs offer great potential as a biomarker for a disease that can be sampled non-invasively from exhaled breath with breath biopsy. However, it is still a great challenge to develop a rapid responsive, highly selective, and sensitive VOC-sensing system. This book analyzes all the challenges and their possible solutions that can be used to achieve target-specific detection and real-time monitoring of the VOC molecules in the exhaled breath. It also covers a detailed discussion of all the sensing materials developed for selective and sensitive detection of VOC molecules and their integration with photonic devices in order to develop miniature technology. It covers various miniature sensing systems that are being exploited in VOC sensing such as interferometer, Bragg grating, microstructured fiber, 3D printed optical sensing systems, etc. The book will also provide an overview of the FEM technique and computation methods used to optimize the optical sensing devices before their practical realization. Photonic sensors for detection of VOC biomarkers aims to provide comprehensive information to early career professionals and boost their existing knowledge in the area of Chemistry and Biomedical Engineering.

  • Practical Process Research and Development

    A Guide for Organic Chemists
    • 3rd Edition
    • Neal G. Anderson
    • English
    Practical Process Research and Development, Third Edition provides a concise, comprehensive, step-by-step framework to support understanding and implement organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries.The book has been heavily updated for its third edition, whilst retaining the basic spirit and structure of the first two editions. Half of the cited references were published after the second edition. It describes steps to prepare active compounds in a cost-effective manner. The chapters on safety and workup have been expanded. Continuous flow operations are discussed in a chapter and highlighted throughout the book. It also provides hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection, optimising catalytic reactions, chiral syntheses, troubleshooting, and green chemistry. Practical Process Research and Development, Third Edition is written primarily for organic chemists as well as chemical engineers. It is well suited for experienced researchers and for those beginning research in industry. It will be useful for drug discovery chemists and for others who want an accessible insight into industrial process R&D.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 90
    • Atta-ur-Rahman
    • English
    Studies in Natural Products Chemistry, Volume 90 covers the synthesis, or testing and recording, of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. With rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 65
    • English
    Progress in Medicinal Chemistry, Volume 65 brings together state-of-the-art reviews and critical insights from leading scientists in the field. Each volume surveys the latest advances in drug discovery and development, with a focus on practical strategies, novel modalities, and real-world case studies. From target identification and structure-based design to optimization of pharmacokinetic properties, safety assessment, and translational science, these volumes provide a comprehensive, up-to-date overview for researchers, graduate students, and professionals working in medicinal chemistry, pharmacology, and related life sciences.Chapters in this new release cover Molecular Glues and Tactics in Hit Finding through to Lead Generation in Drug Discovery – current position and future directions.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 149
    • English
    Advances in Heterocyclic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 89
    • Atta-ur-Rahman
    • English
    Studies in Natural Products Chemistry, Volume 89 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, this book is a welcomed and timely resource.With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

  • Comprehensive Medicinal Chemistry IV

    • 4th Edition
    • David Rotella + 1 more
    • English
    Comprehensive Medicinal Chemistry, Fourth Edition, Four Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. A list of new areas covered includes: - newer assays, techniques, applications in medicinal chemistry - use of artificial intelligence and machine learning in drug discovery and development (prediction of drug efficacy, toxicity, and ADME properties, identification of new drug targets; design of novel drug candidates) - big data - chemical biology - degradation technologies - Precision medicine (targeted therapies; the use of biomarkers to guide drug development)

  • The Alkaloids

    • 1st Edition
    • Volume 95
    • English
    The Alkaloids, Volume 95 continues the longstanding tradition of this authoritative series, offering in-depth and up-to-date reviews on the chemistry, biology, and pharmacology of alkaloids. This volume features comprehensive chapters covering the Chemistry and Biology of Imidazole, Oxazole and Thiazole Alkaloids, The Chemistry and Biology of Securinega Alkaloids, and Renieramycin-type Bis-1,2,3,4-tetrahyd... Marine Natural Products. These chapters provide critical insights into their structures, biosynthesis, and a wide range of biological activities, making this volume an essential reference for researchers in natural products chemistry, medicinal chemistry, and pharmacognosy.

  • Environmental Applications of Covalent Organic Frameworks

    • 1st Edition
    • Mustafa Soylak + 1 more
    • English
    Environmental Applications of Covalent Organic Frameworks offers an in-depth exploration of covalent organic frameworks (COFs), a class of porous polymers known for their structural versatility and robustness. This book delves into the cutting-edge research on COFs and their potential to reduce the environmental impact of chemical processes through green chemistry principles. With a focus on synthesis, functionalization, and practical application, the book presents COFs as transformative materials for pollution absorption, gas storage, and water purification, addressing the critical need for specialized resources that bridge fundamental research and real-world environmental solutions.The text also covers the unique attributes of COFs, including their ability to be tailored to specific environmental challenges through molecular design. It emphasizes the importance of COFs in sustainable development and their role in advancing cleaner and more efficient chemical processes. With insights from leading experts, Environmental Applications of Covalent Organic Frameworks is a crucial resource for researchers, chemists, and environmental scientists aiming to innovate and achieve sustainable progress.

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