Studies in Natural Products Chemistry
- 1st Edition, Volume 77 - May 23, 2023
- Imprint: Elsevier
- Editor: Atta-ur Rahman
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 1 2 9 4 - 5
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 1 2 9 5 - 2
Studies in Natural Products Chemistry, Volume 77 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts… Read more
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Request a sales quoteStudies in Natural Products Chemistry, Volume 77 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.
This book covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.
- Focuses on the chemistry of bioactive natural products
- Contains contributions by leading authorities in the field of natural products chemistry
- Presents sources of new pharmacophores
Natural product chemists working in academia and industry, Medicinal chemists and pharmacologists in academia and industry
- Cover image
- Title page
- Table of Contents
- Studies in Natural Products Chemistry
- Copyright
- Chapter 1. Bixa orellana L. and its implications in human health: Perspectives and new trends
- Introduction
- Materials and methods
- Risks of bias and quality in individual studies
- Results
- Characteristics of the included studies
- Characteristics of the included studies
- Quality and risk of bias individual studies
- Synthesis of results
- Discussion
- Limitations
- Conclusion
- Supplementary material
- Chapter 2. Flavonoids: an alternative therapy for oxidative stress-related diseases
- Introduction
- Chemical structure of flavonoids
- Antioxidant activity
- Antiinflammatory activity
- Cardioprotective activity
- Conclusions
- Chapter 3. Bioactive hybrid compounds from Myrtaceae: Chemical classification and biological activities
- Introduction
- Chemical constituents
- Biological activities
- Conclusion and future perspectives
- Chapter 4. Bioactive chemicals in Helianthus tuberosus L may reduce beta-amyloid cytotoxicity as a potential novel treatment for Alzheimer's disease
- Introduction
- Methods
- Results
- Discussion
- Conclusion and future work
- Abbreviations
- Chapter 5. Curcumin and its derivatives as nutraceuticals: an update
- Introduction
- Physico-chemical properties
- Curcumin as nutraceutical
- Derivatives
- Bioavailability
- Conclusion
- Chapter 6. Natural products and combination therapy as strategies against bacterial biofilm
- Introduction
- Biofilms, antibiotics resistance, and clinical importance
- Treatment of bacterial biofilms
- Natural products
- Natural products from plants
- Natural products from animals
- Natural products from microorganism
- Combination therapy
- Conclusion
- Chapter 7. Phytocompounds as a source for the development of new drugs to treat respiratory viral infections
- Introduction
- Respiratory viruses
- Preclinical toxicity studies
- Clinical trials
- Future perspectives
- Chapter 8. Structure-related relationship: Plant-derived antidiabetic compounds
- Introduction
- Diabetes and pathophysiology
- Treatments
- Structure-activity relationship
- Conclusions and future prospective
- Abbreviations
- Chapter 9. Immunostimulants derived from plants and algae to increase resistance of pacific white shrimp (Litopenaeus vannamei) against vibriosis
- Introduction
- Vibriosis
- Activation of the immune response
- Immunostimulants based on plants and algae
- Selection of natural compounds
- Considerations
- Chapter 10. Plant natural products as autophagy modulators to improve potential cancer therapy
- Introduction
- Plant natural products that target autophagy pathways in tumor cells
- Discussion
- Conclusion
- Chapter 11. Modern solvent-free microwave extraction with essential oil optimization and structure-activity relationships
- Introduction
- Essential oils
- Extraction of EOs using SFME technology
- A systematic review of EO extraction using SFME
- Optimization of EO extraction using RSM
- The proportion of oxygen- and sulfur-containing molecules in EOs
- SAR studies of key molecules in EOs
- Conclusion
- Future perspectives
- Abbreviations
- Chapter 12. Tandem mass spectrometry for Structural characterization of marine natural products with selective exemplary case studies
- Introduction
- Tandem mass spectrometry
- Structural characterization using tandem mass spectrometry
- Dereplication process using tandem MS approach
- Exemplary case studies
- Abbreviations
- Index
- Edition: 1
- Volume: 77
- Published: May 23, 2023
- Imprint: Elsevier
- No. of pages: 474
- Language: English
- Hardback ISBN: 9780323912945
- eBook ISBN: 9780323912952
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Atta-ur Rahman
Atta-ur-Rahman, Professor Emeritus, International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, Pakistan, was the Pakistan Federal Minister for Science and Technology (2000-2002), Federal Minister of Education (2002), and Chairman of the Higher Education Commission with the status of a Federal Minister from 2002-2008. He is a Fellow of the Royal Society of London (FRS) and an UNESCO Science Laureate. He is a leading scientist with more than 1283 publications in several fields of organic chemistry.
Affiliations and expertise
Professor Emeritus, International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, PakistanRead Studies in Natural Products Chemistry on ScienceDirect