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Books in Medicinal chemistry

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    • Synthesis of Best-Seller Drugs

      • 2nd Edition
      • Ruben Vardanyan + 1 more
      • English
      Synthesis of Best-Seller Drugs, Second Edition provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field.

    • Advances in Treatment Methods Towards Emerging Contaminants

      Sources, Occurrences and Health Effects
      • 1st Edition
      • Nabisab Mujawar Mubarak + 3 more
      • English
      Advances in Treatment Methods Towards Emerging Contaminants: Sources, Occurrences and Health Effects is a vital resource for understanding the detection, monitoring, analysis, and remediation of emerging contaminants. This comprehensive guide offers both theoretical insights and practical instructions, making it indispensable for researchers and industry experts. By exploring fundamental aspects such as transformations and toxicology, the book provides a thorough understanding of emerging pollutants and contaminants. In addition to recent advancements in detection techniques, this book features case studies on new remediation strategies, including the use of green technology and nanotechnology.It is an essential reference for policymakers, graduate students, and professionals working in environmental monitoring and waste treatment.

    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 64
      • English
      Progress in Medicinal Chemistry, Volume 64 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

    • Drug Discovery Stories, Volume 2

      • 1st Edition
      • Bin Yu + 1 more
      • English
      Drug Discovery Stories, Volume Two showcases the discovery journeys of recent blockbuster drugs approved between 2023 and 2024, along with promising drug candidates. This book delves into structural biology, biological functions of targets, hit compound identification, hit-to-lead optimization, binding modes, key biological and pharmacokinetic data, and clinical results. It also covers other candidate compounds against the same targets and includes additional content based on the authors' choices. The series addresses the rapid evolution in drug discovery and development, appealing to those in chemical biology, synthetic chemistry, and pharmacology.By highlighting interdisciplinary collaboration, the authors plan to release updated editions every few years to ensure the content reflects the latest achievements and breakthroughs in the field.

    • Drug Discovery and One Health Approach in Combating Infectious Diseases

      A Multi-sectoral Approach to address Infections
      • 1st Edition
      • Kanti Bhooshan Pandey + 2 more
      • English
      Drug Discovery and One Health Approach in Combating Infectious Diseases: A Multi-sectoral Approach to address Infections explores the intersection of drug discovery and the One Health Approach, along with the effectiveness of interdisciplinary approaches to combating infectious diseases. The book covers both holistic and innovative drug discovery methodologies and technologies such as natural compounds, harnessing genomics, proteomics, and nanotechnology. Additionally, the book reviews zoonotic diseases, vaccine development, ethical considerations, and regulatory pathways. Practice case studies demonstrate successful One Health and interdisciplinary initiatives to combating infectious disease.This catalogue of knowledge provides a toolbox of innovative and interdisciplinary solutions of complex issues in drug discovery and infectious disease. It will be a valuable resource to professionals and researchers working in the fields of biomedical sciences, pharmaceutical sciences, infectious disease research, and public health, as well as those engaged in drug discovery, development, and the management of infectious diseases.

    • Amines to Azetidines

      • 1st Edition
      • Navjeet Kaur
      • English
      Amines to Azetidines embarks on an insightful journey into the realm of organic synthesis, spotlighting the intricate processes that lead to the formation of azetidines from amine-based compounds. This book serves as a vital resource for chemists, blending theoretical knowledge with practical methodologies. With a focus on clarity, it elaborates on reaction mechanisms, substrate flexibility, and the role of catalysts in facilitating smooth conversions. Designed for readers ranging from seasoned researchers to eager novices, the text combines accessible language with relevant illustrations, ensuring a seamless understanding of fundamental concepts and advanced techniques alike.In addition to its detailed exploration of synthetic routes, the book provides a wealth of examples that underscore the practical applications of azetidines in pharmaceutical and industrial chemistry. It delves into structure-property relationships, offering insights into how subtle chemical modifications influence reactivity and stability. The inclusion of case studies and experimental data makes this work a dynamic blend of academic rigor and real-world relevance.

    • Discovery and Development of Anti-Prostate Cancerous Agents from Natural Products

      • 1st Edition
      • Goutam Brahmachari
      • English
      Discovery and Development of Anti-Prostate Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This new volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogues that show promising potential to act as anti-prostate cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields.It will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for prostate cancer, highlighting several key structures from natural products and exploring possible future developments in the area.

    • Human Microbiome Drug Targets

      Modern Approaches in Disease Management
      • 1st Edition
      • Genevieve Dable-Tupas + 3 more
      • English
      Human Microbiome Drug Targets: Modern Approaches in Disease Management presents fundamental information on the human microbiome, looking into the relationship between the microbiome and how it changes with specific diseases. Delving into the multifaceted roles of the microbiome in health and disease, the book's chapters discuss the role of the human microbiome in the pathophysiologic understanding of relevant diseases or disorders and their management. As changes in the human microbiome can provide clues to the probable cause and effect of diseases or disorders, as well as the impacts of therapy or intervention, this book is a welcomed addition to the existing research.Explaining how a better understanding of the microbiome and its impact on health and disease can pave the way for future discoveries leading to better health outcomes, this book will be of interest to drug developers, medicinal chemists, microbiologists, infectious disease specialists, biochemists, and students.

    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 63
      • English
      Progress in Medicinal Chemistry, Volume 63 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Specific chapters in this release include Harnessing conformational drivers in drug design, Recent Advances in the Medicinal Chemistry of Heterobifunctional Derivatives for Protein Homeostasis, and A Decade of Antimalarial Drug Discovery: New Targets, Tools and Molecules.

    • Advances in Prodrugs

      Design and Therapeutic Applications
      • 1st Edition
      • Claudiu Trandafir Supuran + 2 more
      • English
      Advances in Prodrugs: Design and Therapeutic Applications provides a versatile tool in prodrug design and development as well as a concrete perspective on clinical and preclinical studies currently available on prodrugs. The first part of this book discusses different chemical classes of prodrugs, with particular emphasis on metabolic pathways and mechanisms involved in the activation of their functional groups. The second part of the book covers therapeutic applications of prodrugs against the most discussed diseases, providing detailed discussion on recent achievements in the field. This book offers researchers involved in drug discovery key criteria for the successful development of prodrug-based therapeutic tools.Prodrugs are inactive drug precursors which undergo different chemical transformation by metabolic processes to provide pharmacologically active compounds. Prodrugs include a broad range of structurally diverse molecules employed for the treatment of several diseases.