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Books in Medicinal chemistry

Photonic Sensors for Detection of VOC Biomarkers

  • 1st Edition
  • May 1, 2025
  • Sridhar Krishnaswamy + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 9 1 6 6 - 1
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 9 1 6 7 - 8
VOCs available in exhaled human breath are the products of metabolic activity in the body and, therefore, any changes in their control level can be utilized to diagnose specific diseases. More than 1000 VOCs have been identified in exhaled human breath along with the respiratory droplets which provide rich information on overall health conditions. This book cover the introductory information on VOCs, their source in the human body, associated diseases, potential sensing materials used for selective detection, and the advancement in their sensing technology. These VOCs offer great potential as a biomarker for a disease that can be sampled non-invasively from exhaled breath with breath biopsy. However, it is still a great challenge to develop a rapid responsive, highly selective, and sensitive VOC-sensing system. This book analyzes all the challenges and their possible solutions that can be used to achieve target-specific detection and real-time monitoring of the VOC molecules in the exhaled breath. It also covers a detailed discussion of all the sensing materials developed for selective and sensitive detection of VOC molecules and their integration with photonic devices in order to develop miniature technology. It covers various miniature sensing systems that are being exploited in VOC sensing such as interferometer, Bragg grating, microstructured fiber, 3D printed optical sensing systems, etc. The book will also provide an overview of the FEM technique and computation methods used to optimize the optical sensing devices before their practical realization. Photonic sensors for detection of VOC biomarkers aims to provide comprehensive information to early career professionals and boost their existing knowledge in the area of Chemistry and Biomedical Engineering.

Discovery and Development of Anti-Prostate Cancerous Agents from Natural Products

  • 1st Edition
  • February 1, 2025
  • Goutam Brahmachari
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 1 8 4 2 - 2
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 1 8 4 3 - 9
Discovery and Development of Anti-Prostate Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This new volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogues that show promising potential to act as anti-prostate cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields.It will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for prostate cancer, highlighting several key structures from natural products and exploring possible future developments in the area.

Human Microbiome Drug Targets

  • 1st Edition
  • October 23, 2024
  • Genevieve Dable-Tupas + 3 more
  • English
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 4 3 6 - 2
Human Microbiome Drug Targets: Modern Approaches in Disease Management presents fundamental information on the human microbiome, looking into the relationship between the microbiome and how it changes with specific diseases. Delving into the multifaceted roles of the microbiome in health and disease, the book's chapters discuss the role of the human microbiome in the pathophysiologic understanding of relevant diseases or disorders and their management. As changes in the human microbiome can provide clues to the probable cause and effect of diseases or disorders, as well as the impacts of therapy or intervention, this book is a welcomed addition to the existing research.Explaining how a better understanding of the microbiome and its impact on health and disease can pave the way for future discoveries leading to better health outcomes, this book will be of interest to drug developers, medicinal chemists, microbiologists, infectious disease specialists, biochemists, and students.

Advances in Prodrugs

  • 1st Edition
  • September 25, 2024
  • Claudiu Trandafir Supuran + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 6 3 5 - 9
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 6 3 4 - 2
Advances in Prodrugs: Design and Therapeutic Applications provides a versatile tool in prodrug design and development as well as a concrete perspective on clinical and preclinical studies currently available on prodrugs. The first part of this book discusses different chemical classes of prodrugs, with particular emphasis on metabolic pathways and mechanisms involved in the activation of their functional groups. The second part of the book covers therapeutic applications of prodrugs against the most discussed diseases, providing detailed discussion on recent achievements in the field. This book offers researchers involved in drug discovery key criteria for the successful development of prodrug-based therapeutic tools.Prodrugs are inactive drug precursors which undergo different chemical transformation by metabolic processes to provide pharmacologically active compounds. Prodrugs include a broad range of structurally diverse molecules employed for the treatment of several diseases.

Specialized Plant Metabolites as Cosmeceuticals

  • 1st Edition
  • July 1, 2024
  • Deepika Kathuria + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 9 1 4 8 - 0
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 3 4 5 - 7
Specialized Plant Metabolites as Cosmeceuticals presents a comprehensive guide to traditional medicinal plants that are used in the field of cosmetics. Chapters cover geographical distribution, extraction of key components from each plant, traditional uses, pharmacognostic characteristics, phytochemistry, pharmacology, toxicology, and future prospects. This book will be a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, cosmetology and the pharmaceutical sciences. As medicinal plants are a rich source of a variety of bioactive secondary metabolites, their wide range of pharmacological applications as antibiotics, antifungals, anticancer agents, and antimicrobial and antiviral applications provide new and exciting avenues.In addition, they have great implications for the food, pharmaceutical, cosmetics and personal care product industries. Secondary metabolites also ecofriendly, cost effective, biocompatible, and cause less side effects as compare to synthetic compounds.

Herbal Formulations, Phytochemistry and Pharmacognosy

  • 1st Edition
  • June 14, 2024
  • Mital Kaneria + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 3 8 3 - 9
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 3 8 2 - 2
Herbal formulations, Phytochemistry and Pharmacognosy combines the principles of natural medicines with refined modern technology that helps the development of more ecofriendly, better effective, easily available, and affordable drug discovery process.The drug discovery process accelerates the design of new leads for various life-threatening diseases. Natural medicines have been an integral part of drug discovery process, and these not only play a major role as a template for the drug discovery but also offer holistic approach for better management of various diseases.The main purpose of this book is to provide the classical and applied knowledge in drug discovery and broadly cover the related aspects such as herbal formulations, phytochemistry and pharmacogenetic research.

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

  • 2nd Edition
  • Volume 2
  • June 1, 2024
  • Bimal Banik
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 6 1 6 4 - 3
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 6 1 6 5 - 0
Green Approaches in Medicinal Chemistry for Sustainable Drug Design: Methods, Second Edition reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context on the growth of green chemistry in relation to drug discovery, the book identifies a range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global experts, the book encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists, and more.This volume covers synthesis methods following green chemistry principles, contributing to sustainability by saving energy, using lesser toxic reagents/solvents/catalysts and environmentally benign sources, including plants and agricultural materials.

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

  • 2nd Edition
  • Volume 1
  • May 30, 2024
  • Bimal Banik
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 6 1 6 6 - 7
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 6 1 6 7 - 4
Sustainable and Green Approaches in Medicinal Chemistry: Applications, Second Edition reveals essential context on the growth of green chemistry in relation to drug discovery, identifying a broad range of practical techniques and useful insights and revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process. The book encourages the growth of green medicinal chemistry and supports medicinal chemists, drug discovery researchers, pharmacologists, and all those in related fields across both academia and industry in integrating these approaches into their own work.This volume includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods.

Dihydropyrimidinones as Potent Anticancer Agents

  • 1st Edition
  • August 15, 2023
  • Mashooq Ahmad Bhat + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 9 0 9 4 - 0
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 3 0 4 - 4
Dihydropyrimidinones as Potent Anticancer Agents gives readers a unique update on scientific knowledge, accomplishments and recent advances in the medicinal chemistry of dihydropyrimidinones in cancer treatment. Dihydropyrimidinones are known to be active scaffold and have been reported to show some exceptional results with regards to malignancies. With ever increasing knowledge and information about synthesis, pharmacology and other aspects of dihydropyrimidinones, there is need to document such information in one place. Since the field of medicinal chemistry is dynamic, with new emerging trends, it provides readily available updated information on chemistry and pharmacology aspects of dihydropyrimidinones in cancer. This book covers everything about dihydropyrimidinones from synthesis, derivatives, mode of action and potential therapeutic targets. It will also provide insights about the clinical trials and way forward in cancer research of dihydropyrimidinones.

Nanotechnology and In Silico Tools

  • 1st Edition
  • July 9, 2023
  • Mital Kaneria + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 4 5 7 - 7
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 4 5 8 - 4
Nanotechnology and In Silico Tools: Natural Remedies and Drug Discovery provides the latest information and updates in the area of drug discovery. The book covers aspects like nanomedicines, bioinformatics, molecular docking, molecular modeling, QSAR, virtual screening, and computational chemistry as well as metabolomics research using various tools. It combines the principles of natural medicines with refined modern technology to help chemists in the development of a more ecofriendly and effective discovery process.The drug discovery process accelerates the design of new leads for various life-threatening diseases and natural medicines. Silico tools have been an integral part of the drug discovery process, playing a major role as a template for drug discovery and offering a holistic approach to better management of various diseases.