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Books in Medicinal chemistry

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Discovery and Development of Anti-Prostate Cancerous Agents from Natural Products

  • 1st Edition
  • February 1, 2025
  • Goutam Brahmachari
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 1 8 4 2 - 2
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 1 8 4 3 - 9
Discovery and Development of Anti-Prostate Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This new volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogues that show promising potential to act as anti-prostate cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields.It will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for prostate cancer, highlighting several key structures from natural products and exploring possible future developments in the area.

Advances in Prodrugs

  • 1st Edition
  • September 25, 2024
  • Claudiu Trandafir Supuran + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 6 3 5 - 9
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 6 3 4 - 2
Advances in Prodrugs: Design and Therapeutic Applications provides a versatile tool in prodrug design and development as well as a concrete perspective on clinical and preclinical studies currently available on prodrugs. The first part of this book discusses different chemical classes of prodrugs, with particular emphasis on metabolic pathways and mechanisms involved in the activation of their functional groups. The second part of the book covers therapeutic applications of prodrugs against the most discussed diseases, providing detailed discussion on recent achievements in the field. This book offers researchers involved in drug discovery key criteria for the successful development of prodrug-based therapeutic tools.Prodrugs are inactive drug precursors which undergo different chemical transformation by metabolic processes to provide pharmacologically active compounds. Prodrugs include a broad range of structurally diverse molecules employed for the treatment of several diseases.

Specialized Plant Metabolites as Cosmeceuticals

  • 1st Edition
  • July 1, 2024
  • Deepika Kathuria + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 9 1 4 8 - 0
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 3 4 5 - 7
Specialized Plant Metabolites as Cosmeceuticals presents a comprehensive guide to traditional medicinal plants that are used in the field of cosmetics. Chapters cover geographical distribution, extraction of key components from each plant, traditional uses, pharmacognostic characteristics, phytochemistry, pharmacology, toxicology, and future prospects. This book will be a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, cosmetology and the pharmaceutical sciences. As medicinal plants are a rich source of a variety of bioactive secondary metabolites, their wide range of pharmacological applications as antibiotics, antifungals, anticancer agents, and antimicrobial and antiviral applications provide new and exciting avenues.In addition, they have great implications for the food, pharmaceutical, cosmetics and personal care product industries. Secondary metabolites also ecofriendly, cost effective, biocompatible, and cause less side effects as compare to synthetic compounds.

Herbal Formulations, Phytochemistry and Pharmacognosy

  • 1st Edition
  • June 14, 2024
  • Mital Kaneria + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 3 8 3 - 9
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 3 8 2 - 2
Herbal formulations, Phytochemistry and Pharmacognosy combines the principles of natural medicines with refined modern technology that helps the development of more ecofriendly, better effective, easily available, and affordable drug discovery process.The drug discovery process accelerates the design of new leads for various life-threatening diseases. Natural medicines have been an integral part of drug discovery process, and these not only play a major role as a template for the drug discovery but also offer holistic approach for better management of various diseases.The main purpose of this book is to provide the classical and applied knowledge in drug discovery and broadly cover the related aspects such as herbal formulations, phytochemistry and pharmacogenetic research.

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

  • 2nd Edition
  • Volume 2
  • June 1, 2024
  • Bimal Banik
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 6 1 6 4 - 3
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 6 1 6 5 - 0
Green Approaches in Medicinal Chemistry for Sustainable Drug Design: Methods, Second Edition reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context on the growth of green chemistry in relation to drug discovery, the book identifies a range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global experts, the book encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists, and more.This volume covers synthesis methods following green chemistry principles, contributing to sustainability by saving energy, using lesser toxic reagents/solvents/catalysts and environmentally benign sources, including plants and agricultural materials.

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

  • 2nd Edition
  • Volume 1
  • May 30, 2024
  • Bimal Banik
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 6 1 6 6 - 7
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 6 1 6 7 - 4
Sustainable and Green Approaches in Medicinal Chemistry: Applications, Second Edition reveals essential context on the growth of green chemistry in relation to drug discovery, identifying a broad range of practical techniques and useful insights and revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process. The book encourages the growth of green medicinal chemistry and supports medicinal chemists, drug discovery researchers, pharmacologists, and all those in related fields across both academia and industry in integrating these approaches into their own work.This volume includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods.

Dihydropyrimidinones as Potent Anticancer Agents

  • 1st Edition
  • August 15, 2023
  • Mashooq Ahmad Bhat + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 9 0 9 4 - 0
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 3 0 4 - 4
Dihydropyrimidinones as Potent Anticancer Agents gives readers a unique update on scientific knowledge, accomplishments and recent advances in the medicinal chemistry of dihydropyrimidinones in cancer treatment. Dihydropyrimidinones are known to be active scaffold and have been reported to show some exceptional results with regards to malignancies. With ever increasing knowledge and information about synthesis, pharmacology and other aspects of dihydropyrimidinones, there is need to document such information in one place. Since the field of medicinal chemistry is dynamic, with new emerging trends, it provides readily available updated information on chemistry and pharmacology aspects of dihydropyrimidinones in cancer. This book covers everything about dihydropyrimidinones from synthesis, derivatives, mode of action and potential therapeutic targets. It will also provide insights about the clinical trials and way forward in cancer research of dihydropyrimidinones.

Nanotechnology and In Silico Tools

  • 1st Edition
  • July 9, 2023
  • Mital Kaneria + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 4 5 7 - 7
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 4 5 8 - 4
Nanotechnology and In Silico Tools: Natural Remedies and Drug Discovery provides the latest information and updates in the area of drug discovery. The book covers aspects like nanomedicines, bioinformatics, molecular docking, molecular modeling, QSAR, virtual screening, and computational chemistry as well as metabolomics research using various tools. It combines the principles of natural medicines with refined modern technology to help chemists in the development of a more ecofriendly and effective discovery process.The drug discovery process accelerates the design of new leads for various life-threatening diseases and natural medicines. Silico tools have been an integral part of the drug discovery process, playing a major role as a template for drug discovery and offering a holistic approach to better management of various diseases.

Medicinal Chemistry of Anticancer Drugs

  • 3rd Edition
  • April 28, 2023
  • Carmen Avendaño + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 8 5 4 9 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 9 6 5 2 - 6
This third edition of Medicinal Chemistry of Anticancer Drugs, provides an updated resource for students and researchers from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. This new edition includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theranostic anticancer agents, and pre-mRNA processing in cancer. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a unique and valuable perspective from the point of view of medicinal chemistry and drug design. It will be useful to undergraduate and postgraduate students of medicinal chemistry, pharmacology, biological chemistry, pharmacy and other health sciences. Researchers and practitioners will find a comprehensive treatment of the topic and a large number of references to reviews and the primary literature.

Recent Frontiers of Phytochemicals

  • 1st Edition
  • April 26, 2023
  • Siddhartha Pati + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 9 1 4 3 - 5
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 8 0 8 - 7
Phytochemicals have been present in human diet and life since the birth of mankind, including the consuming of plant foods and the application of herbal treatments. This coevolutionary interaction of plants and people has resulted in humans' reliance on food and medicinal plants as sources of macronutrients, micronutrients, and bioactive phytochemicals. Phytochemicals can be used as adjuvant agents and sensitizers in traditional antibiotic and anticancer therapy, reducing the potential of selecting resistant microbial strains and cancer cells. Recent Frontiers of Phytochemicals addresses the many processes of potential phytochemical evaluation of known sources, with a focus on phytochemical and pharmacological evaluations, and computational research into the structures and pharmacological mechanisms of natural products and their applications in medicine, food and biotech.