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Elsevier

Books in Organic chemistry

This collection offers extensive coverage of organic synthesis, reaction mechanisms, and functional group chemistry. Showcasing innovative research, green chemistry approaches, and industrial applications, it supports chemists, students, and researchers in designing new molecules and materials. Addressing drug discovery, polymers, and sustainable processes, these titles foster creativity and technical excellence in advancing organic chemistry for societal benefit.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 136
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Studies in Natural Products Chemistry

    Volume 95
    • 1st Edition
    • Atta-ur-Rahman
    • English
    Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

  • Robust Theoretical Models in Medicinal Chemistry

    QSAR, Artificial Intelligence, Machine Learning, and Deep Learning
    • 1st Edition
    • Luciana Scotti + 1 more
    • English
    Robust Theoretical Models in Medicinal Chemistry: QSAR, Artificial Intelligence, Machine Learning, and Deep Learning serves as a valuable resource chock full of applications extending into multiple knowledge domains. The meticulous construction of a robust model holds significance, not only in drug discovery but also in engineering, chemistry, pharmaceutical, and food-related research, illustrating the broad spectrum of fields where QSAR methodologies can be instrumental. The activities considered in QSAR span chemical measurements and biological assays, making this approach a versatile tool applicable across various scientific domains. Currently, QSAR finds extensive use in diverse disciplines, prominently in drug design and environmental risk assessment.Quantitat... Structure-Activity Relationships (QSAR) represent a concerted effort to establish correlations between structural or property descriptors of compounds and their respective activities. These physicochemical descriptors encompass a wide array of parameters, accounting for hydrophobicity, topology, electronic properties, and steric effects, and can be determined empirically or, more recently, through advanced computational methods.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 90
    • English
    Advances in Carbohydrate Chemistry and Biochemistry, Volume 89 in this series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics in this new release include a Roadmap for the Synthesis of Nonreducing Disaccharides as Scaffolds for Complex Biomolecules andFunctionalized D-glucosamine derivatives and their applications.

  • Progress in Heterocyclic Chemistry

    • 1st Edition
    • Volume 38
    • R. Alan Aitken + 1 more
    • English
    Progress in Heterocyclic Chemistry (PHC), Volume 38, is the latest in this annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year’s literature on heterocyclic chemistry and articles on new developing topics of particular interest to heterocyclic chemists. The highlight chapters in Volume 38 are all written by leading researchers in their field and these chapters constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2026. As with previous volumes in the series, Volume 38 will enable academic and industrial chemists, and advanced students, to keep abreast of developments in heterocyclic chemistry in a convenient way.

  • Advances in Physical Organic Chemistry

    • 1st Edition
    • Volume 60
    • English
    Advances in Physical Organic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 89
    • English
    Advances in Carbohydrate Chemistry and Biochemistry, Volume 89 in this series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Computational Studies on Phosphorus Chemistry

    Structure, Spectroscopy and Mechanisms
    • 1st Edition
    • Yu Lan + 3 more
    • English
    Computational Studies on Phosphorus Chemistry: Structure, Spectroscopy and Mechanisms provides a theoretical overview of optimized structures, synthesis, and transformation pathways in phosphorous chemistry. The book introduces the interaction and reaction mechanisms of phosphorus compounds through multiple kinds of simulations and calculations studies. Sections cover theoretical methods and examples; theoretical studies on optimized structures, stereochemistry, spectroscopy, and reaction mechanism of phosphorus-containin... compounds; computational chemistry of the compounds of metal-organophosphor... ligand; the mechanism of organophosphine-cata... reactions; computational biotransformation of phosphorus containing drugs; and computational study of phosphorus-containin... pesticides, phosphorus containing neurotoxic agents, and phosphorus-containin... materials.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 86
    • English
    Advances in Organometallic Chemistry, Volume 86 collects invited chapters from leading researchers, covering advances in synthesis, structure and bonding, reaction mechanisms, and cutting-edge applications in catalysis, materials science, and sustainable chemistry. Chapters in this new release cover Unveiling non-covalent interaction patterns along reaction paths using density-based descriptors, Steering Catalysis with Weak Forces: the Role of Non-covalent Interactions in Reactions with Hydrogen Ions Transfer, New real-space computational methods for the analysis of noncovalent interactions in orgametallic systems, Dispersion Effects in Sterically Crowded Main Group and Transition Metal Alkyls, and more.Additional chapters cover Reassessing Secondary Interactions: Arene and Halogen Contacts in Electron-Rich Metals, making this a comprehensive reference for researchers and graduate students seeking the latest methods, trends, and insights in organometallic science.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 94
    • Atta-ur-Rahman
    • English
    Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

  • New Trends in Cyclodextrins Technology for Pharmaceuticals

    Innovations Based on Cyclodextrins for the Pharmaceutical World
    • 1st Edition
    • Ernesto Rivera García + 1 more
    • English
    New Trends in Cyclodextrins Technology for Pharmaceuticals: Innovations Based on Cyclodextrins for the Pharmaceutical World presents a detailed overview on the properties and applications of cyclodextrins in the pharmaceutical field. The book presents an up-to-date introduction and their properties, exploring current and future methodologies for the use of cyclodextrins in drug delivery systems, biomedical applications, nanomedicine, and in the design dendritic structures and optimize dendrimers are also examined. This new reference is invaluable for researchers studying the development of controlled drug release systems based on cyclodextrins and chemists working in pharmaceuticals or health science.

  • The Organic Chemistry of Drug Design and Drug Action

    • 4th Edition
    • Richard B. Silverman + 2 more
    • English
    The Organic Chemistry of Drug Design and Drug Action, Fourth Edition presents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action. The book's coverage allows readers to extrapolate core principles and mechanisms to many related classes of drug molecules. It reflects the significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while also including significant changes in format and coverage.It is designed for undergraduate and graduate students in chemistry who are studying medicinal chemistry or pharmaceutical chemistry. Users, including research chemists and biochemists working in pharmaceutical and biotechnology industries will find this update to be useful in their daily work.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 93
    • Atta-ur-Rahman
    • English
    Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 92
    • Atta-ur-Rahman
    • English
    Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

  • Contaminants of Emerging Concern in the Environment

    An Analytical Framework
    • 1st Edition
    • Núria Fontanals Torroja + 2 more
    • English
    Contaminants of Emerging Concern in the Environment: An Analytical Framework addresses the pressing issue of contaminants of emerging concern (CECs) in the environment. With the need for new analytical methods to detect these contaminants at trace levels in various environmental matrices, such as air, water, and solid samples, this book provides a comprehensive overview of the analytical framework developed since 2010. By detailing sampling and sample pretreatment techniques, chromatographic separation coupled with mass spectrometry, and portable in-situ determination methods, it equips researchers and practitioners with the necessary tools to effectively analyze and monitor CECs.This book offers practical insights through case studies of analytical procedures, enabling readers to transfer these methods to their own laboratories. It critically discusses the pros and cons of cutting-edge analytical technologies, providing a nuanced understanding of their applications and limitations.

  • Comprehensive Organic Functional Group Transformations III

    • 3rd Edition
    • Gary A Molander
    • English
    Comprehensive Organic Functional Group Transformations III, Four Volume Set is the essential one-stop resource for researchers navigating the vast landscape of organic transformations. This new edition builds on the legacy of its predecessors by offering 130 expertly curated in-depth reviews, each focused on the efficient formation and interconversion of functional groups. This new edition covers breakthrough methodologies that are reshaping the field. Topics like C–H and C–F activation speak to the growing ability to functionalize previously inert bonds, opening new pathways in drug discovery and materials science. The coverage of alkene difunctionalization and dual catalysis highlights the push toward complexity-building in fewer steps, while continuous-flow methods and electrochemistry reflect the shift toward greener, scalable, and more automated synthesis. Organocatalysis, photoredox catalysis, and biocatalysis showcase the integration of biological and light-driven processes, aligning with the broader movement toward sustainable and selective transformations. Whether for teaching, research, or industrial application, Comprehensive Organic Functional Group Transformations III empowers users to quickly identify the best synthetic route for any functional group transformation, making it an indispensable tool for chemists at all levels.

  • The Alkaloids

    • 1st Edition
    • Volume 96
    • English
    The Alkaloids, Volume 96 continues the longstanding tradition of this authoritative series, presenting in-depth and up-to-date reviews on the chemistry and biology of alkaloids. This volume features comprehensive chapters on the chemistry of quinoline alkaloids, the chemistry and biology of securinega alkaloids, and the structure, biological activity, and chemical synthesis of Myrioneuron alkaloids. Together, these contributions provide critical insights into alkaloid structures, biosynthetic origins, biological activities, and synthetic strategies. This volume serves as an essential reference for researchers and advanced students working in natural products chemistry, medicinal chemistry, chemical biology, and pharmacognosy.

  • Cyclodextrin Glucanotransferase

    A Comprehensive Guide from Gene to Applications
    • 1st Edition
    • Kiransinh Rajput
    • English
    Cyclodextrin Glucanotransferase: A Comprehensive Guide from Gene to Applications explores the essential role of cyclodextrin glucanotransferase (CGTase) in starch degradation and its diverse industrial applications. This book serves as a valuable resource for researchers and industry professionals, offering comprehensive insights from the genetic basis of CGTase to its practical applications. The book covers the production of CGTase by different bacterial genera, including Bacillus spp., and their purification strategies. It delves into the structural and functional characteristics of CGTase, highlighting its catalytic mechanisms, substrate specificity, and factors affecting enzyme activity and stability. Additionally, the book explores recombinant CGTases, their properties, and advancements in protein engineering and enzyme immobilization. With a strong focus on practical applications, the book discusses the remarkable properties of cyclodextrins, such as inclusion complex formation, and their wide range of uses in various industries, including pharmaceuticals, textiles, bioremediation, and food. Detailed case studies and real-world examples illustrate how CGTase and cyclodextrins can address specific challenges and drive innovation in these fields.This book is an essential resource for applied science researchers working in the field of starch processing enzymes, providing them with the knowledge to advance their research and development. It also serves as a valuable reference for researchers in the starch processing industries, offering insights into the latest advancements and practical applications of CGTase and cyclodextrins.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 91
    • Atta-ur-Rahman
    • English
    Studies in Natural Products Chemistry, Volume 91 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting- edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and then determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 150
    • English
    Advances in Heterocyclic Chemistry, Volume 150 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics such as Hetero-antiaromatics... 1,3,2,4-benzodithiad... and related compounds, The Synthesis and Properties of Heterocyclic Derivatives of Steroids, Advances in the Chemistry and Applications of Isothiazoles fused with other heterocycles, 3(5)-Amino-1,2,4-tri... versatile synthons for triazole-based fused heterocycles, Photocatalytic Decarboxylative Alkylation: A Mild Strategy for Heterocycle Functionalization, and The Influence of Sulfones on the Synthesis and Properties of Heterocycles.

  • Photonic Sensors for Detection of VOC Biomarkers

    Technological Principles and Medical Applications
    • 1st Edition
    • Sridhar Krishnaswamy + 2 more
    • English
    VOCs available in exhaled human breath are the products of metabolic activity in the body and, therefore, any changes in their control level can be utilized to diagnose specific diseases. More than 1000 VOCs have been identified in exhaled human breath along with the respiratory droplets which provide rich information on overall health conditions. Photonic Sensors for Detection of VOC Biomarkers: Technological Principles and Medical Applications cover the introductory information on VOCs, their source in the human body, associated diseases, potential sensing materials used for selective detection, and the advancement in their sensing technology. These VOCs offer great potential as a biomarker for a disease that can be sampled non-invasively from exhaled breath with breath biopsy. However, it is still a great challenge to develop a rapid responsive, highly selective, and sensitive VOC-sensing system. This book analyzes all the challenges and their possible solutions that can be used to achieve target-specific detection and real-time monitoring of the VOC molecules in the exhaled breath. It also covers a detailed discussion of all the sensing materials developed for selective and sensitive detection of VOC molecules and their integration with photonic devices in order to develop miniature technology. It covers various miniature sensing systems that are being exploited in VOC sensing such as interferometer, Bragg grating, microstructured fiber, 3D printed optical sensing systems, etc. The book will also provide an overview of the FEM technique and computation methods used to optimize the optical sensing devices before their practical realization. Photonic sensors for detection of VOC biomarkers aims to provide comprehensive information to early career professionals and boost their existing knowledge in the area of Chemistry and Biomedical Engineering.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 90
    • Atta-ur-Rahman
    • English
    Studies in Natural Products Chemistry, Volume 90 covers the synthesis, or testing and recording, of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. With rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.

  • Practical Process Research and Development

    A Guide for Organic Chemists
    • 3rd Edition
    • Neal G. Anderson
    • English
    Practical Process Research and Development, Third Edition provides a concise, comprehensive, step-by-step framework to support understanding and implement organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries.The book has been heavily updated for its third edition, whilst retaining the basic spirit and structure of the first two editions. Half of the cited references were published after the second edition. It describes steps to prepare active compounds in a cost-effective manner. The chapters on safety and workup have been expanded. Continuous flow operations are discussed in a chapter and highlighted throughout the book. It also provides hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection, optimising catalytic reactions, chiral syntheses, troubleshooting, and green chemistry. Practical Process Research and Development, Third Edition is written primarily for organic chemists as well as chemical engineers. It is well suited for experienced researchers and for those beginning research in industry. It will be useful for drug discovery chemists and for others who want an accessible insight into industrial process R&D.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 65
    • English
    Progress in Medicinal Chemistry, Volume 65 brings together state-of-the-art reviews and critical insights from leading scientists in the field. Each volume surveys the latest advances in drug discovery and development, with a focus on practical strategies, novel modalities, and real-world case studies. From target identification and structure-based design to optimization of pharmacokinetic properties, safety assessment, and translational science, these volumes provide a comprehensive, up-to-date overview for researchers, graduate students, and professionals working in medicinal chemistry, pharmacology, and related life sciences.Chapters in this new release cover Molecular Glues and Tactics in Hit Finding through to Lead Generation in Drug Discovery – current position and future directions.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 149
    • English
    Advances in Heterocyclic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 89
    • Atta-ur-Rahman
    • English
    Studies in Natural Products Chemistry, Volume 89 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, this book is a welcomed and timely resource.With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

  • Comprehensive Medicinal Chemistry IV

    • 4th Edition
    • David Rotella + 1 more
    • English
    Comprehensive Medicinal Chemistry, Fourth Edition, Four Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. A list of new areas covered includes: - newer assays, techniques, applications in medicinal chemistry - use of artificial intelligence and machine learning in drug discovery and development (prediction of drug efficacy, toxicity, and ADME properties, identification of new drug targets; design of novel drug candidates) - big data - chemical biology - degradation technologies - Precision medicine (targeted therapies; the use of biomarkers to guide drug development)

  • The Alkaloids

    • 1st Edition
    • Volume 95
    • English
    The Alkaloids, Volume 95 continues the longstanding tradition of this authoritative series, offering in-depth and up-to-date reviews on the chemistry, biology, and pharmacology of alkaloids. This volume features comprehensive chapters covering the Chemistry and Biology of Imidazole, Oxazole and Thiazole Alkaloids, The Chemistry and Biology of Securinega Alkaloids, and Renieramycin-type Bis-1,2,3,4-tetrahyd... Marine Natural Products. These chapters provide critical insights into their structures, biosynthesis, and a wide range of biological activities, making this volume an essential reference for researchers in natural products chemistry, medicinal chemistry, and pharmacognosy.

  • Environmental Applications of Covalent Organic Frameworks

    • 1st Edition
    • Mustafa Soylak + 1 more
    • English
    Environmental Applications of Covalent Organic Frameworks offers an in-depth exploration of covalent organic frameworks (COFs), a class of porous polymers known for their structural versatility and robustness. This book delves into the cutting-edge research on COFs and their potential to reduce the environmental impact of chemical processes through green chemistry principles. With a focus on synthesis, functionalization, and practical application, the book presents COFs as transformative materials for pollution absorption, gas storage, and water purification, addressing the critical need for specialized resources that bridge fundamental research and real-world environmental solutions.The text also covers the unique attributes of COFs, including their ability to be tailored to specific environmental challenges through molecular design. It emphasizes the importance of COFs in sustainable development and their role in advancing cleaner and more efficient chemical processes. With insights from leading experts, Environmental Applications of Covalent Organic Frameworks is a crucial resource for researchers, chemists, and environmental scientists aiming to innovate and achieve sustainable progress.

  • Advances in Microscale Electro- and Liquid Phase-Based Separation Techniques

    • 1st Edition
    • Ziad El Rassi
    • English
    Advances in Microscale Electro- and Liquid Phase-Based Separation Techniques summarizes Microscale separation techniques characterized by fast, high resolution, and high efficiency with very reduced sample and solvent consumption. The book summarizes the existing body of knowledge, including hyphenated version to mass spectrometry (cLC-MS), capillary electrophoresis (CE), capillary zone electrophoresis (CZE and CZE-MS), micellar electrokinetic capillary chromatography (MEKC), capillary gel electrophoresis (CGE), capillary isoelectric focusing (CIEF), capillary isotachophoresis (CITP), capillary electrochromatograph... (CEC), microfluidics, and microchips. It then demonstrates the applicability of these techniques to existing and future problems in the analysis of complex mixtures of biochemicals, pharmaceuticals, environmental, and natural products.This book will be valuable to separation scientists, applications scientists, and technicians in industrial outlets, including those in pharmaceuticals, biomedicals, biotechnologies, and food and environmental industries. Students and professors who study separation techniques will also benefit greatly from the book's content.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 85
    • English
    Advances in Organometallic Chemistry provides a comprehensive overview of recent developments and emerging trends in the field of organometallic chemistry. Covering a wide range of topics, the book explores the synthesis, structure, reactivity, and applications of organometallic compounds across various chemical disciplines. Chapters are authored by leading experts and highlight both fundamental research and innovative applications, including catalysis, materials science, bioorganometallic chemistry, and sustainable processes. This volume serves as an essential reference for researchers, graduate students, and professionals seeking up-to-date information on the dynamic and interdisciplinary field of organometallic chemistry.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 88
    • Atta-ur-Rahman
    • English
    Studies in Natural Products Chemistry, Volume 88 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and then determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development.Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.

  • Synthesis of Best-Seller Drugs

    Volume 2
    • 2nd Edition
    • Ruben Vardanyan + 1 more
    • English
    Synthesis of Best-Seller Drugs, Volume Two, Second Edition provides detailed information on the most popular drugs using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas while also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts while also encouraging future developments in this important field.

  • Sonochemical Synthesis of Natural Products and Heterocycles of Pharmaceutical Importance

    Strategy Towards a Sustainable Society
    • 1st Edition
    • Sasadhar Majhi + 1 more
    • English
    Sonochemical Synthesis of Natural Products and Heterocycles of Pharmaceutical Importance: Strategy Towards a Sustainable Society comprehensively summarizes sonochemistry and ultrasound and their applicability to synthetic organic chemistry. Chapters demonstrate the application of sonochemistry to synthesizing molecules of natural origin, organic compounds containing N-heterocycles, O-heterocycles, and S-heterocycles, and the total synthesis and semisynthesis of bioactive compounds under ultrasonication through case studies and detailed illustrations and methodologies. Other sections explore sonochemical organic synthesis under solvent- and catalyst-free conditions, and in an aqueous medium as a green solvent, use of nanoparticles as efficient catalysts, and much more. This is a valuable resource for organic synthesis experts, specialists in natural products, advocates for sustainable chemistry, and researchers and professionals working in total synthesis, semisynthesis, organic synthesis, medicinal chemistry, and the pharmaceutical industries.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 148
    • English
    Advances in Heterocyclic Chemistry, Volume 148 in this series, highlights new advances in the field, with this updated release presenting interesting chapters on topics such as Porphyrins Fused with Heterocyclic Rings: Preparation and Properties, Recent Developments in the Chemistry and Applications of 9-Deazapurines, Use of Deep Eutectic Mixtures in Heterocyclic Chemistry, Revisiting the Ugi Multicomponent Reaction Mechanism and its Application in the Synthesis of Fluorescent Heterocyclics, Application of the Prins Reaction in Heterocyclic Chemistry: Recent Trends, and Pyridinium-phenolate Dyes: Preparation and Properties.

  • Phosphonate Chemistry, Technology and Applications

    Industrial, Environmental, and Energy Applications
    • 1st Edition
    • Konstantinos D. Demadis
    • English
    Phosphonate Chemistry, Technology and Applications: Industrial, Environmental, and Energy Applications presents a comprehensive and interdisciplinary overview of phosphonate compounds, covering synthetic methods, metal phosphonate hybrid materials, and their diverse applications. Key topics include scale and corrosion inhibition, catalytic properties, magnetic and optical functionalities, biomedical uses, and advanced applications in energy, gas capture, imaging, electrocatalysis, and environmental remediation. The book consolidates the latest research from the past decade, offering a systematic, concise, and user-friendly reference that bridges organic, inorganic, and materials chemistry.This is an essential resource for researchers, professionals, and advanced students working across chemistry, materials science, environmental science, and chemical engineering. Its broad scope and practical focus make it the definitive guide for anyone involved in phosphonate-related research or industrial applications.

  • Practical Heterocyclic Chemistry

    A Lab Manual for Syntheses of Heterocycles
    • 1st Edition
    • Vaidhyanathan Balasubramaniyan
    • English
    Practical Heterocyclic Chemistry: A Lab Manual for Syntheses of Heterocycles delves into the entwined history of heterocyclic chemistry and general organic chemistry, tracing their evolution from crude isolation and utilization of bioactive natural products to their current, pivotal role in enhancing the quality of life for humanity and all living organisms. The book provides a concise overview of the enabling technologies and modern toolkits that facilitate complex general organic and heterocyclic syntheses, while also emphasizing the importance of safe and sustainable synthesis processes that are shaped by the game-changing principles of green chemistry.Readers are also made aware of crucial safety considerations in laboratory practice, including hazard mitigation related to starting materials, products, solvents, catalysts, and lab equipment handling. The book covers the essential laboratory skills needed for experiment design, execution, isolation, purification, and characterization, serving as a valuable resource for modern heterocyclic synthesis in academia and industry.

  • Strategic Disconnections in Retrosynthetic Analysis from Pattern Recognition

    An Applied Approach
    • 1st Edition
    • Claudio Trombini
    • English
    Strategic Disconnections in Retrosynthetic Analysis from Pattern Recognition: An Applied Approach introduces retrosynthetic analysis through strategic disconnection methods. It prioritizes disconnections of general structures characterized by specific functionalization patterns or structural motifs like stereogenic centers or bicyclic frameworks. Numerous examples from carefully selected literature illustrate each strategic disconnection, organized by functional or structural pattern, selected disconnection, and polar, radical, or concerted reaction pathways. Developing a deep understanding of these examples enhances 3D visualization skills, critical reasoning, and expertise in synthetic strategies.The book offers insights into advancements in organic synthesis over the last 50 years, with cases of varying complexity from curated literature. Readers can focus on examples that align with their interests or lab work, each case referenced for easy access to primary information. It is ideal for graduate and postdoc students in organic chemistry and synthesis and researchers in industry. Advanced undergraduate students with a solid organic chemistry foundation may also find it beneficial.

  • Organic Electrochemistry

    Fundamentals, Modern Concepts, and Methods
    • 1st Edition
    • Antonio Doménech-Carbó + 1 more
    • English
    Organic Electrochemistry: Fundamentals, Modern Concepts, and Methods offers a comprehensive perspective on the essentials, methodologies, and practical applications of electrochemistry in organic chemistry. Addressing fundamental principles and applied aspects arising from the convergence of electrochemistry and organic chemistry, the book strives to deliver a broad theoretical foundation. It meticulously outlines methods and applications, catering to the interests of researchers, practitioners, and postgraduate students in these domains. With a focus on 'clean' preparative organic chemistry, sections explore the potential of electrosynthesis and elucidates the information offered by electrochemical methods, including their role in processes of biological relevance.Additional... it sheds light on the capabilities of electroanalytical techniques and underscores the importance of the electrochemistry of novel materials, such as organic-inorganic hybrids, organic polymers, and metal-organic frameworks in advancing the frontier of Organic Chemistry.

  • Organic Laboratory Experiments of the Future

    Doing Chemistry in Water
    • 1st Edition
    • Bruce H. Lipshutz + 1 more
    • English
    This lab manual offers students the opportunity to learn organic chemistry through a green chemistry lens, resulting in a more sustainable, future-looking course. Lipshutz and Muchalski’s Organic Laboratory Experiments of the Future: Doing Chemistry in Water approaches the subject with experiments, diagrams, and illustrations shaped by student feedback and honed through years of research and laboratory experience.Organic Laboratory Experiments of the Future: Doing Chemistry in Water includes material on reactions run in water, including but not limited to: ppm Pd-catalyzed couplings, SNAr reactions, nitro group reductions, enzyme-catalyzed reactions, catalytic hydrogenation of olefins, olefin metathesis, reductive aminations, and chemoenzymatic sequences. This lab manual is ideal for courses in organic chemistry, biochemistry, sustainable and green chemistry, and environmentally-resp... lab courses.

  • Synthesis of Best-Seller Drugs

    • 2nd Edition
    • Ruben Vardanyan + 1 more
    • English
    Synthesis of Best-Seller Drugs, Second Edition provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field.

  • Advances in Physical Organic Chemistry

    • 1st Edition
    • Volume 59
    • English
    Advances in Physical Organic Chemistry, Volume 59, the latest release in this definitive resource for authoritative reviews of work in physical organic chemistry, provides a valuable source of information not only for physical organic chemists applying their expertise to both novel and traditional problems but also for non-specialists across diverse areas. The book's hallmark is in its quantitative, molecular level understanding of phenomena across a diverse range of disciplines. Sample chapters in this new release include Coacervate formation, partitioning of molecules into these phases, and artificial signal transduction systems.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 87
    • Atta-ur-Rahman
    • English
    Studies in Natural Products Chemistry, Volume 87 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and then determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development.Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.

  • Phosphonate Chemistry, Technology, and Applications

    Synthesis, Chemistry, and Biomedical Applications
    • 1st Edition
    • Konstantinos D. Demadis
    • English
    Phosphonate Chemistry, Technology, and Applications: Synthesis, Chemistry, and Biomedical Applications gathers important up-to-date information on several modern topics, including the synthetic aspects and chemical transformations of phosphonic acids and their metal derivatives, metal phosphonate hybrid materials, optical properties of metal phosphonates, phosphonate-based systems for calcium-related disorders, metal-bisphosphonate... as controlled release systems, biology of phosphonates and a plethora of biomedical applications.This comprehensive volume is the first part of a 2-volume set. It covers extensively the latest developments in phosphonate chemistry and includes crucial bibliographic information. It explores the constantly expanding world of organic phosphonate compounds and metal phosphonate networks, beyond conventional boundaries. This exploration includes diverse applications derived from these compounds, enhancing the reader's grasp of this dynamic and evolving field.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 88
    • English
    Advances in Carbohydrate Chemistry and Biochemistry, Volume 88 in this series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 87
    • English
    Advances in Carbohydrate Chemistry and Biochemistry, Volume 87 in this series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Metal Organic Frameworks for Energy and Environmental Applications

    • 1st Edition
    • Hongyi Gao + 1 more
    • English
    Metal Organic Frameworks for Energy and Environmental Applications presents a comprehensive overview on the application of metal organic frameworks (MOFs) to energy and environmental areas. MOFs are a promising class of materials due to their tunable structures, high surface area, and versatile functionalities, and are capturing the attention of the global scientific community due to their intersection with environmental concerns. Chapters summarize recent research on MOFS and synthesis strategies for catalysis, including photocatalysis, electrocatalysis, and thermal catalysis, and how MOFs offer enhanced performance, selectivity, and efficiency.Additiona... the vital role MOFs play in energy storage, environmental purification, including degradation of harmful agents, and resource utilization is explored. The book also presents new research on machine learning and data mining, including how researchers can leverage datasets and algorithms to discover new, high-performance MOFs. Metal Organic Frameworks for Energy and Environmental Applications will be a valuable reference for those studying and working in the field of MOFs as they apply to energy, environmental technologies, catalysis, and materials science.

  • Progress in Heterocyclic Chemistry

    • 1st Edition
    • Volume 37
    • R. Alan Aitken + 1 more
    • English
    Progress in Heterocyclic Chemistry, Volume 37 is the latest in this annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year’s literature on heterocyclic chemistry and articles on new developing topics of particular interest to heterocyclic chemists. Chapters are all written by leading researchers in their field, brining a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2024.As with previous volumes in the series, this new release enables academic and industrial chemists and advanced students to keep abreast of developments in heterocyclic chemistry in a convenient way.

  • Chalcones and their Derivatives

    From Synthesis to Applications
    • 1st Edition
    • Mohmmad Younus Wani + 3 more
    • English
    Chalcone is a highly versatile scaffold with a broad range of applications. Serving as a precursor for various organic molecules and natural flavonoids, it exhibits significant biological activities and unique physical properties, including semiconductor behavior, non-linear optical effects, fluorescence, and electronic characteristics. Chalcones have attracted considerable research interest due to their pharmacological potential and the ease with which their biological activity and other properties can be modified through subtle structural changes along the α,β-unsaturated backbone. Beyond their medicinal value, chalcones are utilized in the food and cosmetic industries as additives, owing to their UV-protective qualities. Additionally, they serve as chemosensors and probes in analytical applications. The book Chalcones and Their Derivatives: From Synthesis to Applications explores this remarkable molecule, detailing various synthetic methods, its biological significance, and its diverse applications across multiple fields. Serving as both a comprehensive reference for researchers and an essential guide for postgraduate students, this work provides valuable insights into the development and utilization of chalcone-based molecules for a wide array of purposes.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 84
    • English
    Advances in Organometallic Chemistry, Volume 84, the latest release in this longstanding serial, is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. Sample chapter titles in this new release include Grignard-type Reactions for the Synthesis of Calcium-Based Organometallics, Alkylidyne-alkylidyn... coupling reactions and related chemical transformations at a multimetallic site, and Heterocyclic Organogermanium Derivatives, and much more.

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