Discovery and Development of Anti-Prostate Cancerous Agents from Natural Products
- 1st Edition - February 17, 2025
- Editor: Goutam Brahmachari
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 1 8 4 2 - 2
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 1 8 4 3 - 9
Discovery and Development of Anti-Prostate Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural d… Read more
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Request a sales quoteDiscovery and Development of Anti-Prostate Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This new volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogues that show promising potential to act as anti-prostate cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields.
It will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for prostate cancer, highlighting several key structures from natural products and exploring possible future developments in the area.
- Highlights the use of active agents from natural sources in the development as novel anti-cancer agents
- Features contributions from active researchers and leading experts working in the field
- Includes foundational background information on both prostate cancer mechanisms and natural product structures to support researchers from different disciplines
Graduate students and researchers in the fields of medicinal chemistry, phyto chemistry, combinatorial chemistry, drug research and drug delivery Pharmacologists
- Title of Book
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- List of contributors
- About the editor
- Foreword
- Preface
- Chapter 1. Discovery and development of antiprostate cancerous agents from natural products: an overview
- Abstract
- 1.1 Introduction
- 1.2 An overview of the book
- 1.3 Concluding remarks
- Chapter 2. Molecular signaling of prostate cancer chemoprevention by natural products: current perspectives and future directions
- Abstract
- 2.1 Introduction
- 2.2 Overview of the molecular basis of prostate cancer
- 2.3 Natural compounds with potential to treat prostate cancer
- 2.4 Concluding remarks
- Abbreviations
- References
- Chapter 3. Withanolides as anti-prostate cancer agents of promise
- Abstract
- 3.1 Introduction
- 3.2 Mechanism of action for treatment of prostate cancer
- 3.3 Targeting signaling pathways of prostate cancer
- 3.4 Withanolides
- 3.5 Molecular targets of prostate cancer for withaferin A
- 3.6 Concluding remarks
- Acknowledgments
- Abbreviations
- References
- Chapter 4. A brief sketch on antiprostate cancer activity of plant phenolics
- Abstract
- 4.1 Introduction
- 4.2 Androgens and prostate cancer
- 4.3 Prostate cancer cell lines
- 4.4 Epigenetics aspects in prostate cancer progression
- 4.5 Prostate cancer rodent models
- 4.6 Treatment options
- 4.7 Plant phenolics as antiprostate cancer agents
- 4.8 Plant phenolics under clinical trial studies
- 4.9 Future prospects
- 4.10 Concluding remarks
- Acknowledgment
- Abbreviations
- References
- Chapter 5. Role of lycopene in maintaining human prostate health
- Abstract
- 5.1 Introduction
- 5.2 Prostate-specific antigen
- 5.3 Beneficial effects of lycopene in maintaining prostate health
- 5.4 Concluding remarks
- Funding
- Conflict of interests
- References
- Chapter 6. Anti-prostate cancer potential of some selected natural alkaloids
- Abstract
- 6.1 Introduction
- 6.2 Alkaloids with anti-prostate cancer potential
- 6.3 Concluding remarks
- Abbreviations
- References
- Chapter 7. Triterpenes as promising antiprostate cancer agents
- Abstract
- 7.1 Introduction
- 7.2 Triterpenoids and cancer
- 7.3 Significant triterpenoids from natural sources: promising role against prostate cancer
- 7.4 Concluding remarks
- Abbreviations
- References
- Chapter 8. Flavones and prostate cancer
- Abstract
- 8.1 Introduction
- 8.2 Prostate cancer
- 8.3 Selected natural flavones with antiprostate cancer activity
- 8.4 Future prospects
- 8.5 Concluding remarks
- Conflict of interest
- Abbreviations
- References
- Chapter 9. Medicinal plants from the Mediterranean basin as a source of natural antiprostate cancer agents
- Abstract
- 9.1 Introduction
- 9.2 Medicinal plants from the Mediterranean basin and their main constituents as antiprostate cancer agents
- 9.3 Concluding remarks
- Abbreviations
- References
- Chapter 10. Phytochemicals: targeting therapeutics in managing prostate cancer
- Abstract
- 10.1 Introduction
- 10.2 Causes of prostate cancer
- 10.3 Prostate cancer biomarkers
- 10.4 Clinical diagnosis
- 10.5 Phytochemicals in the treatment of prostate cancer
- 10.6 Concluding remarks
- Abbreviations
- References
- Chapter 11. Nanocarrier mediated targeted delivery of natural products to prostate cancer
- Abstract
- 11.1 Introduction
- 11.2 Encapsulation methods
- 11.3 Concluding remarks
- Acknowledgments
- Abbreviations
- References
- Chapter 12. Total synthetic studies on potent compounds as anti-prostate cancer agents
- Abstract
- 12.1 Introduction
- 12.2 Anti-prostate cancer agents
- 12.3 Concluding remarks
- Abbreviations
- References
- Chapter 13. Antiprostate cancer profile of curcumin-derived synthetic analogs
- Abstract
- 13.1 Introduction
- 13.2 Synthetic endeavors toward curcumin analogs with antiprostate cancer properties
- 13.3 Concluding remarks
- References
- Index
- No. of pages: 500
- Language: English
- Edition: 1
- Published: February 17, 2025
- Imprint: Elsevier
- Paperback ISBN: 9780443218422
- eBook ISBN: 9780443218439
GB
Goutam Brahmachari
Born on April 14, 1969 in Barala, a village in the district of Murshidabad (West Bengal, India), Goutam Brahmachari had his early education in his native place. He received his high school degree in scientific studies in 1986 at Barala R. D. Sen High School under the West Bengal Council of Higher Secondary Education (WBCHSE). Then, he moved to Visva-Bharati (a Central University founded by Rabindranath Tagore at Santiniketan, West Bengal, India) to study chemistry at the undergraduate level. After graduating from this university in 1990, he completed his master’s in 1992, specializing in organic chemistry. After receiving his Ph.D. 1997 in chemistry from the same university, he joined his alma mater the next year and has been a full professor of chemistry since 2011. The research interests of Prof. Brahmachari’s group include synthetic organic chemistry, green chemistry, natural products chemistry, and the medicinal chemistry of natural and natural product-inspired synthetic molecules. With more than 25 years of experience in teaching and research, he has produced over 260 scientific publications, including original research papers, review articles, books, and invited book chapters in the field of natural products and green chemistry. He has already authored/edited 27 books published by internationally reputed major publishing houses, namely, Elsevier Science (The Netherlands), Academic Press (Oxford), Wiley-VCH (Germany), Alpha Science International (Oxford), De Gruyter (Germany), World Scientific (Singapore), CRC Press (Taylor & Francis Group, USA), Royal Society of Chemistry (Cambridge), etc. Prof. Brahmachari serves several scientific bodies in India and abroad, and also many international journals as an editorial member. He has also been serving as co-editor-in-chief for Current Green Chemistry. Prof. Brahmachari is the founder series editor of the Elsevier Book Series ‘Natural Product Drug Discovery’. Prof. Brahmachari is an elected fellow of the Royal Society of Chemistry and a recipient of the CRSI (Chemical Research Society of India) Bronze Medal-2021 (for his contribution to research in chemistry), Dr Basudev Banerjee Memorial Award-2021 (for his contribution to the field of chemical sciences) from the Indian Chemical Society, INSA (Indian National Science Academy) Teachers Award-2019, Dr Kalam Best Teaching Faculty Award-2017, and Academic Brilliance Award, 2015 (Excellence in Research). Prof. Brahmachari was featured in the World Ranking of the Top 2% Scientists (Organic Chemistry Category) in 2020-23, the AD Scientific World Ranking of Scientists in 2022-2024, and as the Scholar GPS Highly Ranked Scholar-2024 (Lifetime, securing a position in the top 0.05% of all scholars worldwide).
Affiliations and expertise
Goutam Brahmachari, PhDFull Professor, Organic Chemistry, Department of Chemistry, Visva-Bharati (a Central University), Santiniketan, West Bengal, IndiaRead Discovery and Development of Anti-Prostate Cancerous Agents from Natural Products on ScienceDirect