Chiral Phosphorous Based Ligands in Earth-Abundant Transition Metal Catalysis
- 1st Edition - May 26, 2023
- Imprint: Elsevier
- Editors: Junliang Zhang, Wenbo Li
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 5 2 2 5 - 8
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 5 2 2 6 - 5
Chiral Phosphorous Based Ligands in Earth-Abundant Transition Metal Catalysis summarizes the most significant progress in the field of chiral phosphine ligand chemistry and a broa… Read more
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Request a sales quoteChiral Phosphorous Based Ligands in Earth-Abundant Transition Metal Catalysis summarizes the most significant progress in the field of chiral phosphine ligand chemistry and a broad range of earth-abundant transition metal/chiral phosphine ligand-catalyzed enantioselective transformations. The book provides an authoritative and in-depth understanding of important topics about asymmetric catalysis based on earth-abundant transition metals/chiral phosphine ligands, making it ideal for organic chemistry researchers working in the field of asymmetric catalysis, synthetic methodologies and total synthesis.The development of new chiral phosphine ligands to achieve precise stereo control in many earth-abundant transition metal-catalyzed reactions is a very important field in organic synthesis, materials science and medicinal chemistry. The asymmetric synthesis promoted by transition metal/chiral phosphine ligands provides one of the most ideal ways to produce valuable optically active chemicals.
- Includes a discussion of state-of-the-art asymmetric organic reactions mediated by earth-abundant transition metals and chiral phosphine ligands
- Features the progress and the prospect of chiral phosphine ligands in asymmetric transition metal catalysis
- Covers the asymmetric reactivity modes of earth-abundant transition metals and phosphine ligands
Organic chemistry researchers working in the field of asymmetric catalysis, synthetic methodologies as well as total synthesis. Researchers working in medicinal, pharmaceutical and industrial chemistry.
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Acknowledgment
- Introduction
- Chapter 1. Design and synthesis of typical chiral bisphosphorus ligands
- 1. Introduction
- 2. Bisphosphorus ligands with carbon chiral center
- 3. Axially chiral bisphosphorus ligands
- 4. Ferrocenyl bisphosphorus ligands
- 5. Spiro backbone-based bisphosphorus ligands
- 6. P-chiral bisphosphorus ligands
- 7. Conclusions
- Chapter 2. The progress of chiral phosphine ligands in asymmetric iron catalysis
- 1. Introduction
- 2. Kumada cross-coupling reactions
- 3. Suzuki–Miyaura coupling reaction
- 4. Diels–Alder reaction
- 5. 1,3-dipolar cycloadditions
- 6. Olefin carbometalation
- 7. Hydrosilylation of ketones
- 8. Asymmetric strecker reaction of azomethine imines
- 9. Asymmetric transfer hydrogenation of ketones and imines
- 10. Asymmetric hydrogenation of ketones and imines
- 11. Conclusion
- Chapter 3. Asymmetric transformations under cobalt catalysis
- 1. Introduction
- 2. Allylic substitutions
- 3. Cycloaddition and cyclization
- 4. Hydrogenation
- 5. Hydrosilylation
- 6. Hydroboration
- 7. Hydroarylation
- 8. Hydrovinylation
- 9. Hydroalkynylation
- 10. Hydroalkylation
- 11. Hydroacylation
- 12. Reductive coupling
- 13. Conclusions
- Chapter 4. Asymmetric transformations under nickel catalysis
- 1. Introduction
- 2. Allylic substitution reactions
- 3. Cross-coupling reactions
- 4. Addition reactions
- 5. Cyclization reactions
- 6. Cycloaddition reactions
- 7. Hydrogenation
- 8. Conclusions
- Chapter 5. Copper/chiral phosphine ligand–catalyzed enantioselective 1,3-dipole cycloaddition reactions
- 1. Introduction
- 2. [3+2] cycloaddition
- 3. Ferrocene-derived chiral phosphine ligands
- 4. Biaryl ring chiral phosphine ligands
- 5. Ming-Phos and its derivative chiral phosphine ligand
- 6. [3+3] cycloaddition
- 7. [3+4] cycloaddition
- 8. [6+3] cycloaddition
- 9. Summary and outlook
- Chapter 6. Copper/phosphine-catalyzed asymmetric radical reactions
- 1. Introduction
- 2. Cu(I)-catalyzed asymmetric amination
- 3. Copper-catalyzed enantioselective cross-coupling
- 4. Conclusions and outlook
- Chapter 7. Asymmetric borylative functionalization of π systems by copper/chiral phosphine
- 1. Introduction
- 2. Asymmetric hydroboration reactions by copper/chiral phosphine
- 3. Tandem reactions initiated by copper–boryl intermediate
- 4. Conclusions
- Chapter 8. Asymmetric hydrosilylation reactions by copper/chiral phosphine
- 1. Introduction
- 2. Asymmetric hydrosilylation of CO bond
- 3. Asymmetric reduction of CC bond of α,β-unsaturated ketones and esters
- 4. Asymmetric hydrosilylation of alkenes
- 5. Conclusions
- Chapter 9. Asymmetric transformations under copper hydride (CuH) catalysis
- 1. Introduction
- 2. Asymmetric C–N bond-forming reactions
- 3. Asymmetric C–C bond-forming reactions
- 4. Conclusions
- Index
- Edition: 1
- Published: May 26, 2023
- No. of pages (Paperback): 320
- No. of pages (eBook): 320
- Imprint: Elsevier
- Language: English
- Paperback ISBN: 9780323852258
- eBook ISBN: 9780323852265
JZ
Junliang Zhang
Prof. Junliang Zhang obtained his B.S. degree in Chemistry in 1997 from Tianjin University and PhD degree from the Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences in 2002 under the supervision of Prof. Shengming Ma. Then he worked as a postdoctoral fellow successively in University of Cologne (Humboldt Fellowship) and then University of Chicago. In 2006, he joined East China Normal University as a full professor. Then he moved to Fudan University in 2017 as professor of chemistry. His recent research interests include enyne chemistry, small ring chemistry and recently focus on developing novel chiral sulfinamide-based phosphine ligands in asymmetric catalysis. He has got several international awards, and published over 150 scientific articles and 5 book chapters.
Affiliations and expertise
Professor of Chemistry, Fudan University, Shanghai, ChinaWL
Wenbo Li
Dr. Wenbo Li obtained her B.S. degree in Chemistry in 2008 and PhD degree in 2013 from East China Normal University under the supervision of Professor Junliang Zhang. Then she began her academic career at East China Normal University in Junliang Zhang’s research group and promoted to associate professor in 2016. Her research focuses on the development of novel reactions and asymmetric transformations. She has authored/co-authored 24 papers and 2 book chapters.
Affiliations and expertise
Associate Professor, East China Normal University, Shanghai, ChinaRead Chiral Phosphorous Based Ligands in Earth-Abundant Transition Metal Catalysis on ScienceDirect