
Handbook of Biomolecules
Fundamentals, Properties and Applications
- 1st Edition - May 23, 2023
- Imprint: Elsevier
- Editors: Chandrabhan Verma, Dakeshwar Kumar Verma
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 1 6 8 4 - 4
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 8 5 3 0 - 7
Handbook of Biomolecules: Fundamentals, Properties and Applications is a comprehensive resource covering new developments in biomolecules and biomaterials and their industria… Read more

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Request a sales quoteHandbook of Biomolecules: Fundamentals, Properties and Applications is a comprehensive resource covering new developments in biomolecules and biomaterials and their industrial applications in the fields of bioengineering, biomedical engineering, biotechnology, biochemistry, and their detection methods using biosensors. This book covers the fundamentals of biomolecules, their roll in living organism, structure, sources, important characteristics, and the industrial applications of these biomaterials. Sections explore amino acids, carbohydrates, nucleic acids, proteins, lipids, metabolites and natural products, then go on to discuss purification techniques and detection methods.
Applications in biomolecular engineering, biochemistry and biomedical engineering, among others, are discussed before concluding with coverage of biomolecules as anticorrosion materials.
- Provides the chronological advancement of biomolecules, their biochemical reaction, and many modern industrial applications in engineering and science
- Serves as a valuable source for researchers interested in the fundamentals, basics and modern applications of biomolecules
- Covers both synthetic and natural biomolecule synthesis and purification processes and their modern applications
- Bridges the gap between the fundamental science of biomolecular chemistry and the relevant technology and industrial applications
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Part I: Fundamental and basics of biomolecules
- Chapter 1: Amino acids: Classification, synthesis methods, reactions, and determination
- Abstract
- Conflict of interest
- 1.1: Introduction
- 1.2: Classification
- 1.3: Synthesis of amino acids
- 1.4: Physical properties
- 1.5: Reactions of amino acids
- 1.6: Sequencing the peptide: Terminal residue analysis
- 1.7: Stereochemistry of amino acids
- 1.8: Applications of amino acids
- 1.9: Conclusion
- 1.10: Useful links
- References
- Chapter 2: Carbohydrate: Introduction and fundamentals
- Abstract
- 2.1: Introduction
- 2.2: Classification of carbohydrates
- 2.3: Configuration of d-glucose
- 2.4: Disaccharides
- 2.5: Polysaccharides
- References
- Chapter 3: Nucleic acids: Components, nomenclature, types, and protection method
- Abstract
- 3.1: Introduction
- 3.2: Types of nucleic acids and their components
- 3.3: Nomenclature of nucleic acids
- 3.4: Structure and function of DNA
- 3.5: Difference between DNA and RNA
- 3.6: Protection method of DNA and RNA
- 3.7: Solid phase synthesis
- 3.8: Replication
- 3.9: Applications of DNA and RNA
- 3.10: Conclusion
- References
- Chapter 4: Proteins: Structure, properties, and importance
- Abstract
- 4.1: Introduction
- 4.2: Peptide
- 4.3: Classification of protein
- 4.4: Structure of protein
- 4.5: Property of protein
- 4.6: Importance of peptide and proteins
- 4.7: Conclusion and future perspective
- References
- Chapter 5: Vitamins and metabolites
- Abstract
- 5.1: Introduction
- 5.2: Classification of vitamins
- 5.3: Sources of vitamins
- 5.4: Nomenclature and structural properties of vitamins
- 5.5: Metabolism of the vitamins
- 5.6: Metabolic functions of the vitamins
- 5.7: Excretion of vitamins as metabolites
- 5.8: Conclusion
- References
- Chapter 6: Enzymes, coenzymes, and pigments
- Abstract
- 6.1: Enzymes: A historical introduction
- 6.2: Coenzymes: A historical introduction
- 6.3: Pigments: A historical introduction
- 6.4: Conclusion and future perspectives
- References
- Further reading
- Chapter 7: Animal and plant hormone
- Abstract
- 7.1: Introduction
- 7.2: Animal hormone
- 7.3: Plant hormone
- 7.4: Conclusion
- References
- Chapter 8: Alkaloids and terpenoids: Synthesis, classification, isolation and purification, reactions, and applications
- Abstract
- 8.1: Introduction
- 8.2: Distribution/occurrence
- 8.3: Classification
- 8.4: Extraction and purification of alkaloids and terpenoids
- 8.5: Biosynthesis of alkaloids
- 8.6: Biosynthesis of terpenoids
- 8.7: Analytical methods for alkaloids and terpenoids
- 8.8: Biological role of alkaloids and terpenoids
- 8.9: Application
- 8.10: Conclusion
- References
- Further reading
- Part II: Isolation, purification and separation
- Chapter 9: Chromatography
- Abstract
- 9.1: Introduction
- 9.2: Applications of chromatography
- 9.3: Conclusion
- References
- Web links
- Chapter 10: Liquid-liquid extraction
- Abstract
- Acknowledgments
- 10.1: Introduction
- 10.2: Organic solvent-based LLE
- 10.3: Water-based LLE
- 10.4: Conclusions
- References
- Chapter 11: Microfluidic devices
- Abstract
- Acknowledgment
- 11.1: Introduction
- 11.2: Challenges and the future
- 11.3: Conclusions
- References
- Part III: Detection methods of biomolecules
- Chapter 12: Biosensors: Detection of biomolecules by biosensors
- Abstract
- 12.1: Introduction
- 12.2: Main parts related to biosensor
- 12.3: Biosensors for biomolecules sensing
- 12.4: Conclusion
- References
- Chapter 13: Electrochemical biosensors for biomolecules
- Abstract
- 13.1: Introduction
- 13.2: EC biosensors for biomolecules
- 13.3: Setup
- 13.4: Materials and equipment
- 13.5: Validation and quality assurance
- 13.6: Step-by-step method details
- 13.7: Top tips
- 13.8: Learning and knowledge outcomes
- 13.9: Conclusions, challenges, and solutions
- References
- Chapter 14: Nanomechanical sensors
- Abstract
- 14.1: Introduction
- 14.2: Classifications of sensors
- 14.3: Characteristics of sensors
- 14.4: Nanomechanical sensors
- 14.5: Fundamental working principles and operation modes of nanomechanical biosensors
- 14.6: Functionalization of nanomechanical sensors
- 14.7: Carbon nanotube-based nanomechanical sensor
- 14.8: Graphene oxide-based nanomechanical sensor in the static mode
- 14.9: Nanomechanical sensors for biological applications
- 14.10: Nanomechanical sensors for chemical and environmental applications
- 14.11: Nanomechanical sensing of biomolecules
- 14.12: Conclusions
- References
- Chapter 15: Colorimetric and fluorescence
- Abstract
- 15.1: Overview: State the research question(s) to be answered
- 15.2: Simple colorimetric assays using UV–visible spectrophotometric technique
- 15.3: CIELab color space
- 15.4: Fluorescence and confocal microscopy in biological tissues. Immunofluorescence
- 15.5: General challenges and solutions
- 15.6: Learning and knowledge outcomes
- 15.7: Top tips
- 15.8: Websites
- References
- Chapter 16: Mass spectrometry
- Abstract
- 16.1: Introduction
- 16.2: Mass spectrometer: Instrumental setup
- 16.3: Ionization source
- 16.4: Data analysis
- 16.5: Common procedural precautions in mass spectrometry
- 16.6: Methodology
- 16.7: Basic research applications of mass spectrometry
- 16.8: Translational research applications of mass spectrometry
- 16.9: Challenges and solutions
- 16.10: Conclusions
- References
- Part IV: Current applications of biomolecules
- Chapter 17: Current applications of biomolecules as anticoronavirus drugs
- Abstract
- 17.1: Introduction
- 17.2: Prospects on COVID-19 infection and early global expansion
- 17.3: Traditional Chinese medicine
- 17.4: Indian Ayurveda
- 17.5: Socioeconomic effects of coronavirus
- 17.6: Conclusion
- References
- Further reading
- Chapter 18: Current application of biomolecules in biomolecular engineering
- Abstract
- Declaration of interest statement
- Conflict of interest statement
- 18.1: Introduction
- 18.2: Biofuels
- 18.3: Challenges in the real world
- 18.4: Conclusion
- References
- Chapter 19: Application of biomolecules in biochemistry
- Abstract
- 19.1: Introduction
- 19.2: Application of carbohydrate in biochemistry
- 19.3: Application of protein in biochemistry
- 19.4: Application of lipid in biochemistry
- 19.5: Application of nucleic acid in biochemistry
- 19.6: Conclusion
- References
- Chapter 20: Current applications of biomolecules in biotechnology
- Abstract
- 20.1: Introduction
- 20.2: Applications of amino acid and peptides
- 20.3: Biosignificance of microbial polysaccharides
- 20.4: Nucleic acid biotechnological applications
- 20.5: Enzymes and biotechnology
- 20.6: Vitamins in biotechnology
- 20.7: Bioengineered lipids
- 20.8: Hormones bioactivity
- 20.9: Applications of flavonoids and alkaloids in biotechnology
- 20.10: Conclusions and future perspectives
- References
- Chapter 21: Current applications of biomolecules in biomedical engineering
- Abstract
- 21.1: Introduction
- 21.2: Biomedical engineering biopolymers
- 21.3: Wound healing
- 21.4: Tissue engineering and regenerative medicine
- 21.5: Conclusions
- References
- Chapter 22: Current applications of biomolecules in biopharmaceuticals and drug discovery
- Abstract
- 22.1: Introduction
- 22.2: Biomolecules as biopharmaceutical agents
- 22.3: Interferon
- 22.4: TNF-α
- 22.5: Interleukins
- 22.6: GCSF/GM-CSF
- 22.7: Erythropoietin
- 22.8: Hormones
- 22.9: Vaccines
- 22.10: Nucleic acids
- 22.11: Biomolecules for drug discovery
- 22.12: Immunogenicity and adverse effects
- 22.13: Future and challenges
- References
- Chapter 23: Flavonoids: Chemistry, biosynthesis, isolation, and biological function
- Abstract
- 23.1: Introduction
- 23.2: The general structure of flavonoids
- 23.3: Chemistry of flavonoids
- 23.4: Biosynthesis of flavonoids
- 23.5: Isolation of flavonoids
- 23.6: Purification of flavonoids
- 23.7: Application of flavonoids
- 23.8: Toxicity
- 23.9: Future perspective
- 23.10: Conclusion
- References
- Chapter 24: Steroids: Isolation, purification, synthesis, reactions, and applications
- Abstract
- 24.1: Introduction
- 24.2: History of steroids
- 24.3: Analysis of steroids
- 24.4: Extraction of steroids
- 24.5: Purification of steroids
- 24.6: Role of mass spectrometry in steroid assays
- 24.7: Emergence of novel catalytic protocols for steroid synthesis
- 24.8: Biological applications of steroids
- 24.9: Conclusion
- References
- Chapter 25: Carbohydrates as green corrosion inhibitors
- Abstract
- 25.1: Introduction
- 25.2: Carbohydrates as green corrosion inhibitors
- 25.3: Conclusions
- References
- Chapter 26: Amino acids and nucleic acids as green corrosion inhibitors
- Abstract
- Declaration of interest statement
- Conflict of interest statement
- 26.1: Introduction
- 26.2: Classification, properties, and applications of amino and nucleic acids
- 26.3: Difference between amino acids and nucleic acids
- 26.4: Amino and nucleic acids as corrosion inhibitors
- 26.5: Metals
- 26.6: Techniques
- 26.7: Mechanism of adsorption
- 26.8: Conclusion
- References
- Chapter 27: Current applications of fatty acids, lignin, and lipids as green corrosion inhibitors
- Abstract
- 27.1: Introduction
- 27.2: Lignin usage as a corrosion inhibitor
- 27.3: Fatty acids
- 27.4: Introducing lipid categories (except fatty acids)
- 27.5: Conclusion
- References
- Chapter 28: Current industrial- and commercial-scale applications of biomolecules
- Abstract
- 28.1: Introduction
- 28.2: Origin of biomolecules
- 28.3: Classification of biomolecules
- 28.4: Characteristics of biomolecules
- 28.5: Production of biomolecules
- 28.6: Commercial applications of biomolecules
- 28.7: Preparation/synthesis of nanomaterials
- 28.8: Biofuels
- 28.9: Dyes and pigments
- 28.10: Industrial applications of biomolecules
- 28.11: Waste treatment
- 28.12: Conclusions
- References
- Further reading
- Chapter 29: Current applications of biomolecules in artificial intelligence and machine learning
- Abstract
- Conflict of interest
- 29.1: Introduction
- 29.2: Applications
- 29.3: Hot spot prediction by ML approaches
- 29.4: Molecular modeling in drug design by ML
- 29.5: Machine learning approaches for predicting biomolecule-disease associations
- 29.6: Prediction of various biomolecule relationships in the molecular association network
- 29.7: Conclusion
- References
- Chapter 30: Plant extracts as bio-based anticorrosive materials
- Abstract
- 30.1: Introduction
- 30.2: Green corrosion inhibitors
- 30.3: Effect of temperature and immersion time on inhibition efficiency
- 30.4: Corrosion-monitoring techniques
- 30.5: Role of artificial intelligence and machine learning in early corrosion detection and intervention
- 30.6: Mechanism of corrosion inhibition
- 30.7: Other significant uses of plant extracts and patents in the field of GCIs (Table 30.6)
- 30.8: Advantages and disadvantages of green CIs
- 30.9: Research gaps and future directions
- 30.10: Conclusion
- Weblinks
- References
- Chapter 31: Recent advancements in biosensing and biosensors
- Abstract
- 31.1: Introduction
- 31.2: Types of biosensors
- 31.3: Applications of biosensors
- 31.4: Biosensors for the diagnostic approach for COVID-19
- 31.5: Advantages and disadvantages of biosensors
- 31.6: Innovations in the field of biosensing and biosensors
- 31.7: Conclusion
- 31.8: Websites links
- References
- Index
- Edition: 1
- Published: May 23, 2023
- No. of pages (Paperback): 668
- No. of pages (eBook): 668
- Imprint: Elsevier
- Language: English
- Paperback ISBN: 9780323916844
- eBook ISBN: 9780323985307
CV
Chandrabhan Verma
Chandrabhan Verma, PhD, works at the Interdisciplinary Research Center for Advanced Materials, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia. He is a member of the American Chemical Society (ACS). His research interests mainly focus on the synthesis and design of environment-friendly corrosion inhibitors used for several industrial applications. Dr. Verma received his PhD degree from the Department of Chemistry at IITBHU, Varanasi, India and MSc degree in organic chemistry (Gold Medalist). Dr. Verma is the author of several research and review articles in peer-reviewed international journals. He has also received several national and international awards for his academic achievements.
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