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Iodine-Assisted Synthesis of Six- and Seven-Membered Heterocycles

1st Edition - February 9, 2023

Author: Navjeet Kaur

Paperback ISBN:

9 7 8 - 0 - 4 4 3 - 1 5 2 2 5 - 2

eBook ISBN:

9 7 8 - 0 - 4 4 3 - 1 5 2 2 6 - 9

Iodine-Assisted Synthesis of Six- and Seven-Membered Heterocycles covers both existing and the latest methods for the synthesis of various six- and seven-membered heterocycles… Read more

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Iodine-Assisted Synthesis of Six- and Seven-Membered Heterocycles covers both existing and the latest methods for the synthesis of various six- and seven-membered heterocycles using iodine. Covering an important and rapidly growing branch of heterocyclic chemistry, this book allows users easy access to the synthetic protocols for the synthesis of heterocycles, acting as a guide for how to make these important compounds employed as agrochemicals, pharmaceuticals, and veterinary products, using particular reagents. This book will be of interest to students, pharmacologists, biochemists, and organic and medicinal chemists.

Chapter-1: Six-membered N-heterocycles: alkenes and alkynes

1.1 Introduction

1.2 Synthesis of six-membered N-heterocycles from alkenes

1.2.1 Synthesis of piperidines

1.2.2 Synthesis of quinolines

1.2.3 Synthesis of indolizines

1.2.4 Synthesis of fused six-membered N-heterocycles

1.3 Synthesis of six-membered N-heterocycles from alkynes

1.3.1 Synthesis of pyridines

1.3.2 Synthesis of quinolines

1.3.3 Synthesis of isoquinolines

1.3.4 Synthesis of fused six-membered N-heterocycles
References
Chapter-2: Six-membered N-heterocycles: amines and carbonyl compounds

2.1 Introduction

2.2 Synthesis of six-membered N-heterocycles from amines and carbonyl compounds

2.2.1 Synthesis of quinolines

2.2.2 Synthesis of fused six-membered N-heterocycles

2.3 Synthesis of six-membered N-heterocycles from amines and more than one carbonyl compounds

2.3.1 Synthesis of pyridines

2.3.2 Synthesis of quinolines

2.3.3 Synthesis of fused six-membered N-heterocycles
References
Chapter-3: Six-membered N,N-heterocycles

3.1 Introduction

3.2 Synthesis of quinazolines

3.3 Synthesis of fused quinazolines

3.4 Synthesis of quinoxalines

3.5 Synthesis of fused quinoxalines
References
Chapter-4: Six-membered N-, N,N-, N,N,N-, and N,N,N,N-heterocycles

4.1 Introduction

4.2 Synthesis of piperidines

4.3 Synthesis of quinolines

4.4 Synthesis of fused quinolines

4.5 Synthesis of pyrimidines

4.6 Synthesis of piperazines

4.7 Synthesis of fused pyrimidines

4.8 Synthesis of triazines and tetrazines
References
Chapter-5: Six-membered O-heterocycles

5.1 Introduction

5.2 Synthesis of pyrans

5.2.1 Synthesis of pyrans from CHO and ene/yne group containing compounds

5.2.2 Synthesis of pyrans from OH and ene/yne group containing compounds

5.3 Synthesis of benzopyrans
References
Chapter-6: Six-membered O-heterocycles: cyclization of ene and OH moieties

6.1 Introduction

6.2 Synthesis of pyrans

6.3 Synthesis of benzopyrans

6.4 Synthesis of fused pyrans
References
Chapter-7: Six-membered O,O-, O,O,O-, and O,N-heterocycles

7.1 Introduction

7.2 Synthesis of dioxanes

7.3 Synthesis of fused dioxanes

7.4 Synthesis of trioxanes

7.5 Synthesis of oxazines

7.6 Synthesis of benzoxazines

7.7 Synthesis of fused oxazines
References
Chapter-8: Six-membered S-heterocycles

8.1 Introduction

8.2 Synthesis of benzothiopyrans

8.3 Synthesis of dithiolanes

8.4 Synthesis of benzothiazines

8.5 Synthesis of thiadiazines
References
Chapter-9: Seven-membered heterocycles

9.1 Introduction

9.2 Synthesis of seven-membered N-heterocycles

9.3 Synthesis of seven-membered O-heterocycles

9.4 Synthesis of seven-membered S-heterocycles
References