
Advances in Clinical Chemistry
- 1st Edition, Volume 111 - November 17, 2022
- Imprint: Academic Press
- Editor: Gregory S. Makowski
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 8 5 9 0 - 1
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 8 6 0 0 - 7
Advances in Clinical Chemistry, Volume 111, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scient… Read more

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Request a sales quote- Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science
- Authored by world renowned clinical laboratory scientists, physicians and research scientists
- Presents the international benchmark for novel analytical approaches in the clinical laboratory
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: Advances in antimicrobial resistance testing
- Abstract
- 1: Introduction
- 2: Culture-based antimicrobial susceptibility testing
- 3: Detection of AMR using mass spectrometry
- 4: Detection of AMR using PCR-related technologies
- 5: Detection of AMR using isothermal amplification technologies
- 6: Detection of AMR using microarray-based techniques
- 7: Determining AMR using high-throughput sequencing
- 8: Summary
- Acknowledgements
- References
- Chapter Two: Urinary exosomes: Diagnostic impact with a bioinformatic approach
- Abstract
- 1: Significance of urinary exosomes
- 2: Literature search on “urinary exosomes”
- 3: Protocols for isolation of urinary exosomes
- 4: Characterization of exosomes
- 5: Impact of urinary exosome cargo in disease pathogenesis
- 6: Urinary exosomes in different types of cancer
- 7: Exosome-disease correlation
- 8: Conclusions and future perspectives
- Acknowledgments
- Conflicts of interest
- References
- Chapter Three: Biomarkers in metabolic syndrome
- Abstract
- 1: Introduction
- 2: Definition and diagnosis of metabolic syndrome
- 3: Metabolic syndrome biomarkers
- 4: Conclusion
- References
- Chapter Four: Physins in digestive system neoplasms
- Abstract
- 1: Introduction
- 2: Structure of physin family proteins
- 3: Distribution of physins in digestive system
- 4: Physins as biomarkers in digestive neoplasms
- 5: Concluding remarks and prospective
- Acknowledgments
- References
- Chapter Five: Stress system and related biomarkers in Parkinson's disease
- Abstract
- 1: Introduction
- 2: Homeostasis and the stress response
- 3: Neurobiology of stress: Link with PD pathogenesis
- 4: The clinical relationship between stress and PD
- 5: Stress biomarkers for Parkinson's disease
- 6: Comparison of stress-related biomarkers in other disease cohorts
- 7: Stress and PD treatment
- 8: Limitations and future perspectives
- 9: Conclusions
- References
- Chapter Six: Drug testing in the era of new psychoactive substances
- Abstract
- 1: Immunoassay
- 2: Liquid chromatography tandem-mass spectrometry (LC-MS/MS)
- 3: High-resolution mass spectrometry
- 4: Conclusions
- References
- Index
- Edition: 1
- Volume: 111
- Published: November 17, 2022
- Imprint: Academic Press
- No. of pages: 282
- Language: English
- Hardback ISBN: 9780323985901
- eBook ISBN: 9780323986007
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board-certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President Clinical Laboratory Services Hartford HealthCare in Connecticut.