Oxetane Synthesis
- 1st Edition - March 22, 2023
- Imprint: Elsevier
- Author: Navjeet Kaur
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 8 9 4 7 - 0
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 8 9 4 8 - 7
Oxetane Synthesis rings play an important role as versatile motifs both in the overall formation of natural products and in synthetic organic chemistry. Oxetanes are important… Read more
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Request a sales quoteOxetane Synthesis rings play an important role as versatile motifs both in the overall formation of natural products and in synthetic organic chemistry. Oxetanes are important motifs in pharmaceutical chemistry that can confer improved metabolic and physicochemical properties. These developments continue to enhance the use of oxetanes in medicinal chemistry. Thanks to the growing commercial accessibility of oxetane possessing building blocks, together with improved approaches for the formation, oxetanes are likely to be progressively utilized in medicinal chemistry programs. Oxetanes are becoming valuable as a result of their vast diversity of uses in medicinal chemistry and varying applications.
Several procedures have been developed for the formation and ring-opening of oxetanes to give important compounds in agrochemical, medicinal and material sciences. Novel approaches have been developed for the synthesis of oxetanes. These methods depend on both established synthetic approaches and development of many novel approaches for the formation of oxetanes.
- Highlights methods for the synthesis of oxetanes
- Includes new developments that enhance the use of oxetanes in medicinal chemistry
- Covers new approaches recently developed for the synthesis of oxetanes
Students and Researchers in Chemistry, Synthetic Chemists, Organic Chemists, Academics and professionals in the field of catalytic and organic chemistry
- Cover image
- Title page
- Table of Contents
- Copyright
- Author biography
- Preface
- Abbreviations
- 1. Synthesis of oxetanes from epoxides
- 1.1. Introduction
- 1.2. Synthesis of oxetanes from epoxides
- 1.3. Metal-catalyzed synthesis of oxetanes from epoxides
- 1.4. Methylsulfonium methylide-assisted synthesis of oxetanes from epoxides
- 1.5. Base-assisted synthesis of oxetanes from epoxides
- 1.6. Lithium reagent-assisted synthesis of oxetanes from epoxides
- 2. Synthesis of oxetanes from ketenes—Part I
- 2.1. Introduction
- 2.2. Synthesis of oxetanes from ketenes
- 2.3. Synthesis of oxetanes from ketene carbonyls
- 2.4. Synthesis of oxetanes from ketenes and carbonyl compounds
- 3. Synthesis of oxetanes from ketenes—Part II
- 3.1. Introduction
- 3.2. N-Heterocyclic carbene-assisted synthesis of oxetanes from ketenes and carbonyl compounds
- 3.3. Metal-assisted synthesis of oxetanes from ketenes and carbonyl compounds
- 3.4. KHMDS-assisted synthesis of oxetanes from ketenes and carbonyl compounds
- 4. Synthesis of oxetanes from carbonyl compounds
- 4.1. Introduction
- 4.2. Synthesis of oxetanes from carbonyl compounds
- 4.3. Synthesis of oxetanes from two carbonyl compounds
- 4.4. Synthesis of oxetanes from other carbonyl heterocycles
- 5. Synthesis of oxetanes by addition of ene and yne compounds to carbonyl compounds
- 5.1. Introduction
- 5.2. Synthesis of oxetanes by addition of alkenes to carbonyl compounds
- 5.3. Synthesis of oxetanes by addition of allenes to carbonyl compounds
- 5.4. Synthesis of oxetanes by addition of alkynes to carbonyl compounds
- 6. Synthesis of oxetanes from acid, alcohol, and carbonyl moiety-containing compounds
- 6.1. Introduction
- 6.2. Synthesis of oxetanes from acid moiety-containing compounds
- 6.3. Synthesis of oxetanes from acid and alcohol moieties containing compounds
- 6.4. Synthesis of oxetanes from acid and carbonyl moieties containing compounds
- 7. Synthesis of oxetanes from alcohols
- 7.1. Introduction
- 7.2. Synthesis of oxetanes from alcohols
- 8. Synthesis of oxetanes by addition of alkenes and alkynes to alcohols
- 8.1. Introduction
- 8.2. Synthesis of oxetanes by addition of alkenes to alcohols
- 8.3. Synthesis of oxetanes by addition of alkynes to alcohols
- 9. Synthesis of oxetanes from diols
- 9.1. Introduction
- 9.2. Synthesis of oxetanes from diols
- 10. Synthesis of oxetanes from halo alcohols
- 10.1. Introduction
- 10.2. Synthesis of oxetanes from halo alcohols
- 11. Synthesis of oxetanes from alkenes under photochemical irradiation
- 11.1. Introduction
- 11.2. Photochemical synthesis of oxetanes from alkenes and aldehydes
- 11.3. Photochemical synthesis of oxetanes from alkenes and ketones
- 11.4. Photochemical synthesis of oxetanes from alkenes and diones
- 12. Synthesis of oxetanes under photochemical irradiation
- 12.1. Introduction
- 12.2. Photochemical synthesis of oxetanes
- 13. Synthesis of fused oxetanes under photochemical irradiation
- 13.1. Introduction
- 13.2. Photochemical synthesis of oxetanes fused with five-membered carbocycles
- 13.3. Photochemical synthesis of oxetanes fused with five-membered heterocycles
- 13.4. Photochemical synthesis of oxetanes fused with six-membered carbocycles
- 13.5. Photochemical synthesis of oxetanes fused with six-membered heterocycles
- 13.6. Photochemical synthesis of oxetanes fused with seven-membered carbocycles
- Glossary
- Index
- Edition: 1
- Published: March 22, 2023
- Imprint: Elsevier
- No. of pages: 400
- Language: English
- Paperback ISBN: 9780443189470
- eBook ISBN: 9780443189487
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Navjeet Kaur
Dr. Navjeet Kaur received her BSc from Panjab University Chandigarh (Panjab, India) in 2008. In 2010, she completed her MSc in Chemistry from Banasthali Vidyapith. She was awarded with PhD in 2014 by the same university. With 11 years of teaching experience, she has published over 160 scientific research papers, review articles, book chapters, and monographs in the field of organic synthesis in national and international reputed journals. She has published five authored books: with Elsevier. She secured her place amongst top 2% scientists of the world in 2017 (single year ranking), 2018 (full career wise ranking), 2019 [full career wise ranking with 424 world rank (04 in India) and single year ranking with 03 world rank (01 in India)] and 2020 (full career wise ranking with 372 world rank and single year ranking with 126 world rank). In 2021, Dr. Kaur was chosen as a candidate for membership by Royal Society of Research, London, England, UK with full waiver of application fees. She is serving as an Editor-in-Chief of the “Advanced Chemicobiology Research” journal.
Affiliations and expertise
Lovely Professional University, IndiaRead Oxetane Synthesis on ScienceDirect