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Synthesis of Azetidines from Imines by Cycloaddition Reactions
- 1st Edition - January 10, 2023
- Author: Navjeet Kaur
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 9 2 0 4 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 9 2 0 5 - 0
Synthesis of Azetidines from Imines by Cycloaddition Reactions presents several methodologies for the synthesis of azetidines from imines by cycloaddition reactions… Read more
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Request a sales quoteSynthesis of Azetidines from Imines by Cycloaddition Reactions presents several methodologies for the synthesis of azetidines from imines by cycloaddition reactions. The azetidines, known as important contribution of science to humanity, are important organic compounds that have occupied a basic position in the pharmaceutical chemistry for over a hundred years because of their biological activities. They are the fundamental skeleton of several antibiotics, probiotics and alkaloids. The synthesis of azetidines is a constant challenge for medicinal chemists, hence this book comprehensively describes azetidine ring synthesis.
With this book, readers will be able to quickly assess possible synthetic approaches and evaluate whether preparation of a four-membered nitrogen containing ring is reasonable.
- Highlights cycloaddition reactions of imines
- Covers the synthesis of azetidines
Chapter-1: Synthesis of azetidines from imines
1.1 Introduction
1.2 Synthesis of azetidines from imines
1.3 Synthesis of azetidines from imines and carbon monoxide
1.4 Synthesis of azetidines from haloimine compounds
References
Chapter-2: Synthesis of azetidines by cycloaddition of imines to alkenes
2.2 Synthesis of azetidines by cycloaddition of imines to alkenes
2.3 Synthesis of azetidines by LDA-assisted cycloaddition of imines to alkenes
2.4 Synthesis of azetidines by lithium-assisted cycloaddition of imines to alkenes
References
Chapter-3: Synthesis of azetidines by metal-catalyzed cycloaddition of imines to alkenes
3.2 Synthesis of azetidines by metal vinylidene-catalyzed cycloaddition of imines to alkenes
3.3 Synthesis of azetidines by metal-catalyzed cycloaddition of imines to alkenes
3.4 Synthesis of azetidines by titanium-catalyzed cycloaddition of imines to alkenes
References
Chapter-4:
Synthesis of azetidines by cycloaddition of imines to ketenes-I4.1 Introduction
4.2 Synthesis of azetidines by cycloaddition of imines to ketenes
References
Chapter-5: Synthesis of azetidines by cycloaddition of imines to ketenes-II
5.2 Synthesis of azetidines by ferrocene-assisted cycloaddition of imines to ketenes
5.3 Synthesis of azetidines by N-heterocyclic carbene-assisted cycloaddition of imines to ketenes
5.4 Synthesis of azetidines by metal-assisted cycloaddition of imines to ketenes
5.5 Synthesis of azetidines by polymer-supported reagent-assisted cycloaddition of imines to ketenes
5.6 Synthesis of azetidines by triethylamine-assisted cycloaddition of imines to ketenes
References
Chapter-6: Synthesis of azetidines by cycloaddition of imines to carbonyl compounds
6.2 Synthesis of azetidines by intramolecular cycloaddition of imine to carbonyl moiety using NaHMDS
6.3 Synthesis of azetidines by cycloaddition of imines to carbonyl compounds using zinc reagents
6.4 Miscellaneous synthesis of azetidines by cycloaddition of imines to carbonyl compounds
References
Chapter-7: Synthesis of azetidines by cycloaddition of imines to acetyl chloride moiety
7.2 Synthesis of azetidines by cycloaddition of imines to acetyl chloride moieties
7.3 Synthesis of azetidines by cycloaddition of imines to acetoxyacetyl chlorides
7.4 Synthesis of azetidines by cycloaddition of imines to methoxyacetyl chlorides
7.5 Synthesis of azetidines by cycloaddition of imines to oxazolidinylacetyl chlorides
7.6 Synthesis of azetidines by cycloaddition of imines to proline acid chlorides
References
Chapter-8: Synthesis of azetidines by cycloaddition of imines to aromatic acetyl chloride moiety
8.2 Synthesis of azetidines by cycloaddition of imines to benzyloxyacetyl chlorides
8.3 Synthesis of azetidines by cycloaddition of imines to phenoxyacetyl chlorides
8.4 Synthesis of azetidines by cycloaddition of imines to phenylacetyl chlorides
References
Chapter-9: Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride-I
9.2 Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride
9.3 Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride using triethylamine and dioxane
References
Chapter-10: Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride-II
10.2 Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride using triethylamine
References
- No. of pages: 386
- Language: English
- Edition: 1
- Published: January 10, 2023
- Imprint: Elsevier
- Paperback ISBN: 9780443192043
- eBook ISBN: 9780443192050
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