Natural Products as Anticancer Agents

1st Edition - November 21, 2023
Authors: Bimal Krishna Banik, Aparna Das
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 9 7 1 0 - 2
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 9 7 1 1 - 9

Natural Products as Anticancer Agents introduces the different types of natural products that have been used for cancer treatment. Divided into four parts, covering antica… Read more

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Natural Products as Anticancer Agents introduces the different types of natural products that have been used for cancer treatment. Divided into four parts, covering anticancer agents derived from terrestrial plants, anticancer agents derived from the marine environment, and anticancer agents derived from microorganisms, as well as evaluation of new anticancer agents, each part includes discussion of the properties, synthesis/extraction, storage, mechanism of action, and usage of the molecules. Discussion of the future prospects in anticancer natural products—including several new trends and an indication of where research in this area is likely to go in the future—is also included.

Cover Image
Title Page
Copyright
Table of Contents
Authors biographies
Preface
Part 1 Anticancer agents derived from terrestrial plants
Chapter 1 Anticancer activity of natural compounds from leaves of the plants
1.1 Introduction
1.2 β-caryophyllene and β-caryophyllene oxide
1.3 Cadinol and related compounds
1.4 Eugenol and related compounds
1.5 Essential oil from leaves of different plants
1.6 Conclusion
Acknowledgment
References
Chapter 2 Anticancer activity of natural compounds from stems/barks of the plants
2.1 Introduction
2.2 Taxanes
2.3 Tannins
2.4 Lupeol
2.5 Betulin and betulinic acid
2.6 Ursolic acid
2.7 Amooranin
2.8 Skimmianine
2.9 Berberine
2.10 Quercetin
2.11 Apigenin
2.12 Conclusion
Acknowledgment
References
Chapter 3 Anticancer activity of natural compounds from roots of the plants
3.1 Introduction
3.2 Harmine
3.3 Licochalcone A
3.4 Withaferin A
3.5 Panaxadiol
3.6 Curcumin
3.7 Gingerol
3.8 Punarnavine
3.9 Isoliquiritigenin
3.10 Damnacanthal
3.11 Plumbagin
3.12 Conclusion
Acknowledgment
References
Chapter 4 Anticancer activity of natural compounds from fruits and vegetables
4.1 Introduction
4.2 Chrysin
4.3 Lycopene
4.4 Ferulic acid
4.5 Catechins
4.6 Ellagic acid
4.7 Cyanidin
4.8 Silymarin
4.9 Gallic acid
4.10 Conclusion
Acknowledgment
References
Part 2 Anticancer agents derived from marine environment
Chapter 5 Anticancer activity of natural compounds from marine animals
5.1 Introduction
5.2 Didemnins
5.3 Ecteinascidins
5.4 Psammaplins
5.5 Aeroplysinins
5.6 Halichondrins
5.7 Pelorusides
5.8 Variolins
5.9 Dolastatins
5.10 Kahalalides
5.11 Lamellarins
5.12 Asterosaponins
5.13 Bryostatins
5.14 Conclusion
Acknowledgment
References
Chapter 6 Anticancer activity of natural compounds from marine plants
6.1 Introduction
6.2 Conclusion
Acknowledgment
References
Part 3 Anticancer agents derived from microorganisms
Chapter 7 Anticancer activity of natural compounds from bacteria
7.1 Introduction
7.2 Anticancer compounds from bacteria associated with marine organisms
7.3 Anticancer compounds from bacteria associated terrestrial plant/environment/soil
7.4 Conclusion
Acknowledgment
References
Chapter 8 Anticancer activity of natural compounds from fungi
8.1 Introduction
8.2 Anticancer compounds from fungi associated with terrestrial plant/environment/soil
8.3 Anticancer compounds from bacteria associated with marine organisms and plants
8.4 Conclusion
Acknowledgment
References
Part 4 Evaluation of new anticancer agents
Chapter 9 Anticancer drugs from hormones and vitamins
9.1 Introduction
9.2 Anticancer activity of hormones
9.3 Anticancer activity of vitamins
9.4 Conclusion
Acknowledgment
References
Chapter 10 Future prospects in anticancer natural products
10.1 Introduction
10.2 Current status of natural products as anticancer agents
10.3 Future perspectives of natural products anticancer
Acknowledgment
References
Index

Bimal Krishna Banik

Bimal Krishna Banik conducted postdoctoral research at Case Western Reserve University and Stevens Institute of Technology. He is a FRSC and CChem of the Royal Society of Chemistry, UK and a Fellow of the Indian Chemical Society.  Professor Banik has conducted chemistry and chemical biology research on diverse cancers; antibiotics; hormones; and green chemistry. As the Principal Investigator, he has been awarded $7.25 million grants from US NIH and US NCI. He has 372 publications along with 485 presentation abstracts and 6500 citations. He has presided 20 symposiums at the American Chemical Society National Meetings and over 2 dozen conferences at the National and International level, including 1 at the Nobel Prize celebration in Germany. He is a reviewer of 93, editorial board member of 28, editor-in-chief of 14, founder of 4, associate editor of 4 and guest editor of 6 journals. Professor Banik has served as the chair of the University of Texas M. D. Anderson Cancer Center’s drug discovery symposiums and directed their analytical chemistry laboratory and has been selected for the Indian Chemical Society’s Life-Time Achievement Award;  Mahatma Gandhi Pravasi Honor Medal from the UK Parliament; US National Society of Collegiate Scholars’ Best Advisor Award for students; Professor P. K. Bose Endowment Medal; Dr. M. N. Ghosh Gold Medal; University of Texas Board of Regents’ Outstanding Teaching Award; 5 top-cited papers Awards by Elsevier Journals; approximately 50 certificates of excellences in his profession; Indian Association Community Service Award; ACS Member Service Award; US National Cancer Institute  Webpage recognition; Best Researcher and Mentor Awards by the UTPA; Burdwan University Eminent Alumnus recognition; UTPA’s Award for Excellence in International Studies.

Affiliations and expertise

Professor, Prince Mohammad Bin Fahd University, Kingdom of Saudi Arabia.

Aparna Das

Aparna Das obtained her PhD degree in Material science/nanophysics from Joseph Fourier University based upon the work on “Semiconductor Quantum Dots for Opto-chemical Sensor Application” at French Alternative Energies and Atomic Energy Commission (CEA), France. Her postdoctoral experiences include working as a research scientist at the California Nano Systems Institute and Electric Engineering Department, University of California, Los Angeles (UCLA), USA, and as an experienced researcher at the Nanowiring-Marie Curie Initial Training Network, Georg August Universität Göttingen, Germany. Dr Das’s research interests include Computer-assisted Physico-chemical methods, quantum mechanical calculations, interdisciplinary science (Biology, Chemistry, and Physics) for drug development, computer-aided drug design, microwave applications, photochemical reactions, III-Nitride based chemical sensors, solar cells, optoelectronic devices, synthesis of thin layers and nanostructures including Quantum wells, quantum dots, and nanowires. She is the author of two books and received the young women researcher award, European microscopy society (EMS) outstanding paper awards, and several international fellowships such as the Marie-Curie fellowship, CEA-CNRS research fellowship, and Brain Korea 21 fellowship.

Affiliations and expertise

Assistant Professor, Department of Mathematics and Natural Sciences, Prince Mohammad Bin Fahd University, Kingdom of Saudi Arabia

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health