Recent Advances in Organometallic Chemistry

Synthetic, Mechanistic and Medicinal Perspective

1st Edition - April 10, 2024
Editors: Azaj Ansari, Vinod Kumar
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 9 0 5 9 6 - 1
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 0 7 1 9 - 4

Recent Advances in Organometallic Chemistry: Synthetic, Mechanistic and Medicinal Perspective highlights recent advancements in the field of organometallic chemistry. Contai… Read more

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Recent Advances in Organometallic Chemistry: Synthetic, Mechanistic and Medicinal Perspective highlights recent advancements in the field of organometallic chemistry. Containing essential information for researchers and advanced-level students, especially those working in chemical synthesis, the book describes the role of organometallic compounds in different combinations in organic synthesis and pharmaceuticals as well as discussing spectral, magnetic and sensing features of the compounds. Including the role of computational investigations towards the mechanistic study of biomimic complexes in catalytic transformation reactions, the book provides a large number of examples along with their leading applications in other fields.Each chapter covers basic strategies, which are illustrated along with examples of the latest advancements in the field and in-depth explanations.

Cover image
Title page
Table of Contents
Copyright
List of contributors
About the editors
Chapter 1. An overview of organometallic compounds: important terms and terminologies
Abstract
1.1 Introduction
1.2 Important terms and terminologies
1.3 Classifications
1.4 Common methods of preparation
1.5 General mechanisms
1.6 Applications in emerging fields
1.7 Future prospective and scope
1.8 Problems with solutions
1.9 Objective type questions
References
Chapter 2. Organometallic compounds: bonding and spectral characteristics
Abstract
2.1 Introduction
2.2 Bonding in organometallic compounds
2.3 Organometallic compounds containing metal–metal bond
2.4 Spectral characteristics of organometallics
2.5 Nuclear magnetic resonance spectroscopy
2.6 Electron paramagnetic resonance
2.7 Electron nuclear double resonance
2.8 Electron spin echo envelope modulation
2.9 Infrared spectroscopy
2.10 Ultraviolet–visible spectroscopy
2.11 Raman spectroscopy
2.12 X-ray absorption spectroscopy
2.13 Summary
References
Chapter 3. Frontier organometallic catalysis: traditional methodologies and future implications
Abstract
3.1 Introduction
3.2 Fundamental principles
3.3 Common methods of preparation
3.4 Mechanism Involved
3.5 Recent developments with examples
3.6 Applications in emerging fields
3.7 Future prospective and scope
3.8 Summary
3.9 Problems with solutions
3.10 Objective type questions
References
Chapter 4. Coordination cages and clusters as functional materials
Abstract
4.1 Introduction
4.2 Common methods of preparation
4.3 Mechanism involved
4.4 Recent developments with examples
4.5 Future prospective and scope
4.6 Summary
4.7 Problems with solution
4.8 Objective type questions
References
Chapter 5. C–H activation: A sustainable approach for the synthesis of functionalized heterocycles
Abstract
5.1 Introduction
5.2 Principle of C–H activation
5.3 Method of preparation and mechanisms involved in C–H activation: recent applications in organic synthesis
5.4 Future prospective and scope
5.5 Summary
References
Chapter 6. Organotransition metal chemistry in asymmetric catalysis mediated by different transition metal N-heterocyclic carbene complexes
Abstract
6.1 Introduction
6.2 Fundamental principles
6.3 Common methods of preparation
6.4 Mechanism involved
6.5 Recent developments with examples
6.6 Applications in emerging fields
6.7 Future prospective and scope
6.8 Summary
6.9 Problems with solutions
6.10 Objective type questions
References
Chapter 7. Organophosphorus compounds: recent developments and future perspective
Abstract
7.1 Introduction
7.2 Fundamental principles
7.3 Common methods of preparation
7.4 Classification of pincer complexes
7.5 Summary
7.6 Problems with solutions
7.7 Objective-type questions
References
Chapter 8. Synthesis of silicon and germanium organometallic compounds and their applications in catalysis
Abstract
8.1 Introduction
8.2 Synthesizing of silicon and germanium organometallic compounds
8.3 Catalysis
8.4 Future prospective and scope
8.5 Summary
8.6 Problems with solutions
8.7 Objective type questions
References
Chapter 9. Sensing application of organometallic compounds
Abstract
9.1 Introduction
9.2 Fundamental principles
9.3 Common methods of preparation
9.4 Mechanism involved
9.5 Recent developments with examples
9.6 Applications in emerging fields
9.7 Future prospective and scope
9.8 Summary
9.9 Problems with solutions
9.10 Objective type questions
References
Chapter 10. Bioorganometallic chemistry: a new horizon on organometallic landscape
Abstract
10.1 Introduction
10.2 Shift from platinum metal based therapeutics to other bio-compatible less toxic nonplatinum complexes
10.3 Organoselenium compounds as potent chemotherapeutic agents
10.4 Other biological activities of organoselenium compounds
10.5 Different plausible mechanisms of action for bioorganometallic complexes
10.6 Summary
10.7 Problems with solutions
10.8 Objective type questions
References
Chapter 11. Azole-based organometallic compounds as bioactive agents
Abstract
11.1 Introduction
11.2 Azoles as antifungal drugs
11.3 Mechanistic approach of azole-based organometallic complexes for infection
11.4 Azole based metal-complexes and their use in medicinal chemistry
11.5 Recent advances of azole-based organometallic compounds
11.6 Summary
11.7 Objective type questions
References
Chapter 12. Hybrid organometallic compounds as potent antimalarial agents
Abstract
12.1 Introduction
12.2 Life cycle of malaria
12.3 Some common examples of antimalarial drugs
12.4 An approach to hybrid antimalarial drugs
12.5 Hybrid organometallic antimalarial compounds
12.6 Recent developments with examples: some representative hybrid organometallic antimalarial agents
12.7 Future prospective and scope
12.8 Summary
12.9 Objective type questions
References
Chapter 13. Therapeutic approach of polynuclear organometallic complexes
Abstract
13.1 Introduction
13.2 Fundamental principles
13.3 Common methods of preparation
13.4 Mechanism involved
13.5 Applications in emerging fields
13.6 Future prospective and scope
13.7 Summary
Problems with solutions
Objective type questions
References
Chapter 14. Role of organometallic compounds in neglected tropical diseases
Abstract
14.1 Introduction
14.2 Diseases
14.3 Summary
14.4 Problems with solutions
14.5 Objective type questions
References
Chapter 15. A computational approach toward the role of biomimetic complexes in hydroxylation reactions
Abstract
15.1 Introduction
15.2 Computational details
15.3 Recent developments with examples
15.4 Mechanism involved
15.5 Factors affecting hydroxylation
15.6 Applications in emerging fields
15.7 Future prospective and scope
15.8 Summary
Problems with solutions
Objective type questions
References
Index

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health

Recent Advances in Organometallic Chemistry

Synthetic, Mechanistic and Medicinal Perspective

Purchase options

Institutional subscription on ScienceDirect

Azaj Ansari

Vinod Kumar