Studies in Natural Products Chemistry

1st Edition, Volume 80 - February 24, 2024
Editor: Atta-Ur Rahman
Language: English
Hardback ISBN:
9 7 8 - 0 - 4 4 3 - 1 5 5 8 9 - 5
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 1 5 5 9 0 - 1

Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fasci… Read more

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Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.

With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

Cover image
Title page
Table of Contents
Studies in Natural Products Chemistry
Copyright
List of contributors
Chapter 1. Tryptophan and its role in sleep and mood
1. Introduction to the history of tryptophan
2. Structure, pharmacokinetics, and mechanism of action
3. The microbiota–gut–brain axis in tryptophan metabolism
4. Therapeutic uses of tryptophan
5. Conclusion
Chapter 2. Polyphenols: A promising nutritional strategy for the prevention and treatment of hypertension
1. Introduction
2. Methods
3. Endothelial function and hypertension
4. Dietary polyphenols
5. Antihypertensive and vasodilator actions of polyphenols
6. Human studies
7. Conclusions and perspectives
Acknowledgments
Chapter 3. Catalytic synthesis of 3(2H)-isoquinolinones and 3-aminoisoquinolines
1. General introduction
2. 3(2H)-isoquinolinones
3. 3-aminoisoquinolines
4. Conclusions
Chapter 4. Progress in the study of natural neo-clerodane diterpenoids
1. Origin of natural NCDs
2. Structures of natural NCDs
3. Biological activities of NCDs
4. Conclusion
Chapter 5. Physiological and molecular responses of nanoparticle application to plants grown under abiotic and biotic stress
1. Introduction
2. Nanotechnology
3. Nanotechnology in agriculture
4. Abiotic and biotic stress factors and effects of nanoparticle application on plant growth in these stress conditions
5. Molecular responses of nanoparticle application to plants grown under abiotic and biotic stress
6. Conclusion and future prospects
Chapter 6. Bio-functional activities of agavins on health
1. Introduction
2. Fructans: Chemical structure, nomenclature, and dietary source
3. Agave tequilana Weber var. Azul
4. Bio-functionalities of agavins
5. Genomics and agavins
6. Use of agave fructans in the food industry
7. Toxicity and adverse effects
8. Conclusion
Abbreviations
Chapter 7. Agave species: A comprehensive review of taxonomy, chemistry, ethnobotany, and ethnopharmacology
1. Introduction
2. History
3. Phylogeny and biogeography
4. Botany
5. Cytology and histology
6. Phytochemistry
7. Pharmacological activities
8. Precautions and contraindications for the use of Agaves
9. Uses and valorization of agave fibers
10. Alcoholic beverages obtained from Agaves
11. Agave in the fields of fodder, silage, agriculture, and food
12. Agave in the areas of environment and energy
13. Conclusion
Chapter 8. Structure, expression regulation, and applications of fungal laccases, an interesting prospective in biotechnology
1. Laccases proteins and their role in microbial ecology
2. Laccase-producing fungi
3. Induction of laccase activity in producing fungi
4. The catalytic cycle of a laccase-mediator system: Main reactions catalyzed by laccases
5. Application of laccases
6. Challenges in the application of laccases
7. Laccases sequences
8. Genetic regulation of laccases
9. Laccase: Biotechnological and industrial uses, scientific research and development, and patents
10. Laccase: A look ahead
Chapter 9. Natural compounds against allergic and pseudoallergic reactions: Molecular mechanisms of action
1. Introduction
2. Mast cells
3. Current therapies for the treatment of allergic reactions
4. Natural products with antiinflammatory activity
5. Antiallergic nitrogen-containing natural compounds and their mechanism of action
6. Coumarins
7. Stilbenes
8. Phenylpropanoids
9. Benzoic acid derivatives
10. Lignans
11. Flavonoids
12. Tannins
13. Terpenes, sesquiterpenes, triterpenes, and steroids
14. Xanthones
15. Other polyphenolic compounds
16. Discussion
17. Concluding remarks
Abbreviations
Chapter 10. Plant-based natural product chemistry: An overview of the multistep journey involved in scientific validation of traditional knowledge
1. Introduction
2. Plant-based bioactive molecules
3. Approaches used for the selection of plant material for possible research
4. Biosynthesis of metabolites and their storage in plants
5. Extraction of secondary metabolites from raw plant material
6. Conventional extraction techniques
7. Non-conventional extraction techniques
8. Fractionation of crude plant extract
9. Isolation techniques
10. TLC-based analysis (staining and tailing agents, UV visualization)
11. Spectroscopic techniques for the characterization of isolated molecules
12. Crystallization: A vital tool for structure analysis
13. Bioactivity evaluation
14. Quality control of medicinal plants: A vital challenge
15. Conclusion
Abbreviations
Chapter 11. Challenges involved in the creation of scientific evidence for tobacco control
1. Introduction
2. Conclusion
Chapter 12. Polyphenol antioxidants in vegetable oils: A scientific and technological prospecting
1. Introduction
2. Addition of plant extracts to vegetable oils as potential natural antioxidants
3. Addition of plant extracts to vegetable oils as potential natural antioxidants: A perspective of patent documents
Conclusion
Chapter 13. The genus Chenopodium: Phytochemicals and biological activities
1. Introduction
2. Phytochemical components of the genus Chenopodium
3. Components of Chenopodium plant essential oils
4. Biological activities of the genus Chenopodium
5. Conclusions
Chapter 14. Beneficial health effects of collagen hydrolysates
1. Introduction
2. Collagen structure
3. Collagen sources
4. Hydrolysis of collagen
5. Amino acid sequences
6. Bioactive properties of collagen hydrolysates
7. Conclusion
Index

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health

Studies in Natural Products Chemistry

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Atta-Ur Rahman