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Elsevier

Books in Life sciences

  • Diagnostic, Prognostic, and Therapeutic Role of MicroRNAs in Head and Neck Cancer

    • 1st Edition
    • Ashok Kumar + 3 more
    • English
    Diagnostic, Prognostic and Therapeutic Role of MicroRNAs in Head and Neck Cancer provides detailed information on various miRNA-based approaches for the diagnosis, prognosis, and treatment of HNSCC. The book encompasses various miRNA-based point-of-care diagnostics and drug delivery systems for HNSCC, along with information on clinical trials for improved clinical outcomes in HNSCC patients. In addition, it provides a comprehensive overview of currently available miRNAs associated with HNSCC and their extensive application for early diagnosis, prognosis, and treatment. Scientists and clinicians looking to win the battle against HNSCC will benefit from the book's sections on early diagnosis to improve treatment, increase treatment response rates, and reduce mortality rates. Recently, miRNA-based diagnostics and therapeutics have gained considerable attention among the scientific community. MiRNAs are known to have great potential as biomarkers for early diagnosis, prediction, and prognosis of HNSCC, and play a role in development of targeted gene therapy.

  • The Science and Art of Sensory Processing Sensitivity

    • 1st Edition
    • Bianca P. Acevedo
    • English
    The Science and Art of Sensory Processing Sensitivity provides an up-to-date and novel scientific perspective on the biologically based Sensory Processing Sensitivity (SPS) trait— which is associated with enhanced awareness, depth of cognitive processing, and heightened responsivity to the environment and other individuals. This second volume by B.P. Acevedo, following “The Highly Sensitive Brain,” takes a scientific perspective on its exploration of SPS, but adds to the existing body of literature on high sensitivity by including an enhanced discussion on the proposed mechanisms linking it with depression, anxiety, and burnout.In addition, this second volume explores SPS’ relationship to other relevant personality traits, such as the Big Five, creativity, and sensation seeking; and sheds light on how their varying combinations give rise to different outcomes for highly sensitive persons (HSPs). A unique contribution of this volume is its detailed examination of the role of culture, gender, biology, aging, and the environment (including the workplace) on the expression (or repression) of high sensitivity.Also, unlike previous books, this volume takes a broad perspective on outcomes related to being highly sensitive to shine a light on the non-trivial issue plaguing many HSPs: diminished quality of life, happiness, and well-being. As such, a major contribution of the second volume on the science of SPS, is its extensive description of scientifically-based techniques that might improve the quality of life for those with high SPS.Thus, this volume may appeal to a wide audience, including both HSPs and those in their social network (friends, partners, physicians, parents, educators, and clinicians) who wish to better understand SPS, those with the trait, and how to enhance well-being among the highly sensitive.

  • Alzheimer's Disease Research Guide

    Animal Models for Understanding Mechanisms and Medications
    • 1st Edition
    • Takaomi C. Saido
    • English
    Alzheimer's Disease Research Guide: Animal Models for Understanding Mechanisms and Medications provides researchers with a comprehensive guide, detailing every aspect of Alzheimer's Disease research, including chapters on neuroinflammation, immunotherapy, biomarkers, and animal modeling. This book begins with historical perspectives of both pathological chronology and pathological biochemistry in relation to Alzheimer’s disease. Other chapters review Amyloidogenic AB and Non-Amyloidogenic tau and Metabolism of AB major components to the research and understanding of Alzheimer’s research. The book concludes with specific treatment chapters including how to develop safe, effective, and inexpensive medications and the application of genome editing to the treatment of Familial Alzheimer's Disease.Written by world renowned expert in Alzheimer’s research, this book is a valuable resource for all researchers.

  • Redox Signaling in Wound Healing in Elderly Populations: Theoretical Basis, Part 1

    • 1st Edition
    • Volume 2
    • English
    Redox Signaling in Wound Healing in Elderly Populations: Theoretical Basis, Part 1 deals with wounds in different types and locations (diabetic, ischemic, post-operational) in subcellular and macro dimensions, examine their relationship with aging aim to target deteriorating redox signaling cascades, and will also focus on promising therapeutic approaches. Understanding the indication for the use of new therapeutics targeting the illuminated pathways in wound healing will help adjust treatment regimens befitting modern medicine. Ineffective redox adaptation and disseminated oxidative injury are the hallmarks of continuing oxidative stress. However, oxidative stress cannot be simply described as the imbalance between ROS formation and antioxidant defense capacity; it also covers impairment in redox sensing and signaling pathways. The term oxidative stress is an expression that is losing its use in modern redox biology. It is now an accepted fact that ROS cannot be described as an apparent enemy or friend. Its optimum level modulates signal transduction and stress responses by acting as a second messenger for redox-sensitive cascades. Redox-dependent second messengers are generated in subcellular locations according to specific rules and regulations. Their appearance depends on cellular needs in response to external and internal stimuli variations. A good understanding of the wound healing cascades, which deteriorate especially in advancing ages, is critical in developing the most appropriate approach. To understand the redox signaling mechanisms and healing cascades in wound healing, to pioneer new pharmacoactive drugs that can be developed based on these mechanisms, to reveal the deteriorating dynamics in the elderly patient group, and to propose new treatment methods suitable for the advanced age group.

  • Hormones

    • 1st Edition
    • Volume 142
    • English
    Hormones, Volume 142, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Estrogen receptor binding mechanism with agonist and antagonist, Biomarker Identification of Medullary Thyroid Carcinoma from Gene Expression Profiles Considering without-treatment and with-treatment Studies – A Bioinformatics approach, Exploring the Role of Estrogen and Progestins in Breast Cancer: A Genomic Approach to Diagnosis, Structural insights on ER-alpha, ER-Beta, progesterone and their drug-targets interactions in Breast cancer, The predictive ability of myokines in patients with chronic heart failure, and much more.Other chapters cover Endogenous and artificial regulators of pituitary glycoprotein hormone receptors, Insight into vitamin D3 action within the ovary - basic and clinical aspects, Hormonal basis of seasonal changes in metabolism, Viral mimicry and endocrine system: Divulging the importance in host-microbiome crosstalk, Recombinant hormones as biopharmaceuticals: past, present and future, Thyroid hormone biosynthesis and its role in brain development and maintenance, and much more.

  • Case-Based Practical Training of Colposcopy and Cervical Pathology

    With Diagrams and Images
    • 1st Edition
    • Nadereh Behtash + 5 more
    • English
    Case-Based Practical Training in Colposcopy and Cervical pathology: With Diagrams and Images is an illustrated reference to improve theoretical and practical knowledge to understand and perform colposcopy. Cervical cancer screening has advanced a great deal over the last century, and the medical field has come far in detect early pre-cancer and invasive cancer of the cervix though colposcopy and pathology. Anyone in the field of gynecology, pathology, and oncology will find this book useful to better understand the different levels of prevention, including vaccinations and screening and for students to correctly understand colposcopy and cervical pathology through real illustrated case studies. The book’s aim is for for prevention and treatment of anogenital and HPV related -diseases and supports the goal of the World Health Organization to cure cervical cancer by 2030.

  • Bio-organic Amendments for Heavy Metal Remediation

    Water, Soil and Plant Approaches and Technologies
    • 1st Edition
    • Allah Ditta + 3 more
    • English
    Bio-organic Amendments for Heavy Metal Remediation: Water, Soil and Plant Approaches and Technologies focuses on these core continuum media to explore remediation options using microbial, organic, and combined approaches. This volume in the Plant Biology, Sustainability and Climate Change series offers a comprehensive view of techniques and approaches for addressing contamination by heavy metals. It provides a comprehensive view of the challenge, with a focus on the bioremediation of heavy metals contamination using ecotechnological approaches for protecting the soil, water, and plant continuum.As anthropogenic activities increasingly negatively impact natural resources, there has been significant disturbance of the water, soil, and plant continuum due to the accumulation of heavy metals. The bioaccumulation of heavy metals in the food chain could pose life-threatening effects on plants as well as humans, and there is need to find effective and sustainable remediation options. The application of bio-organic amendments could serve as a sustainable solution to this problem.

  • Metabolomics for Personalized Vaccinology

    • 1st Edition
    • Mahbuba Rahman
    • English
    Metabolomics for Personalized Vaccinology provides insight into the importance of personalized vaccines in the clinical and research environments. It explores the development of personalized vaccines, which requires in-depth knowledge of the patient’s health status, particularly the immune system, and on metabolomics, the closest indicator of the disease phenotype. Specifically, the book provides an understanding of how metabolomics might be employed in personalized vaccinology and how the metabolic pathway of the host’s system is altered by vaccine administration.Over the past few years, researchers have published articles on personalized vaccines, but these are sparse. Therefore, compiling information on this topic gives the reader an overview of the progress of the field, despite being at its infancy.Metabolomics for Personalized Vaccinology is ideally suited for researchers and postgraduate students who are interested in clinical and nonclinical studies where metabolites are used for the identification of disease and therapeutic targets.

  • Essentials of Translational Pediatric Drug Development

    From Past Needs to Future Opportunities
    • 1st Edition
    • Elke Gasthuys + 3 more
    • English
    Essentials of Translational Pediatric Drug Development: From Past Needs to Future Opportunities provides integrated and up-to-date insights relevant for both translational researchers and clinicians active in the field of pediatric drug development. The book covers all key aspects from different stakeholder perspectives, providing a literature overview and careful reflection on state-of-the-art approaches. It will be an ideal guide for researchers in the field who are designing and performing high quality, innovative pediatric-adapted drug development by helping them define needs/challenges and possible solutions that advance and harmonize pediatric drug development.Despite the broad consensus that children merit the same quality of drug treatment as any other age group, children remain frequently neglected during drug research and development. Even with the adoption of multiple legislations addressing this problem, the lack of efficacy and safety data of marketed as well as newly developed drugs still remain in the pediatric population.

  • Quality Assurance Management

    A Comprehensive Overview of Real-World Applications for High Risk Specialties
    • 1st Edition
    • Gayathri De Lanerolle + 3 more
    • English
    Quality Assurance Management: A Comprehensive Overview of Real-World Applications for High Risk Specialties demonstrates how to best design and implement standard operating procedures (SOPs) to ensure protocol and regulation adherence. The book showcases similarities and differences between healthcare and academic quality assurance systems, resulting in counter-productivity and performance issues, in addition to regulatory inspection preparedness. It uses the processes and standards of the UK to demonstrate how to combine QA and research building into ‘building blocks’ that share a common pathway for effective project design, analysis and unbiased interpretation of collated data.This book fills a gap, providing original research in QA that especially focuses on specialist areas. It will be of use to research and clinical staff working in clinical research within healthcare, academia and industry.

  • Learning Deep Brain Stimulation Management through Clinical Cases

    • 1st Edition
    • Martijn Beudel
    • English
    Learning Deep Brain Stimulation Management through Clinical Cases reviews the clinical practice of applying deep brain stimulation (DBS) to patients with movement disorders. The book explores the cardinal aspects of applying DBS in diverse movement disorders based on patient’s needs. Every case answers all questions, providing case descriptions and step-by-step procedures for optimal replication. Every chapter includes a clinical decision support system (CDSS) depicted in flowcharts that can be used for reference. Deep Brain Stimulation (DBS) uses electrical stimulation to regulate electrical signals in neural circuits to and from identified areas in the brain to improve movement symptoms.The management of DBS in a movement disorders can be challenging, optimizing patient journeys and grasping all clinical aspects of the highly technological therapy. Hence, this book provides the informaiton necessary to embrace new breakthroughs.

  • Current Status of Prostate Cancer: Diagnosis, Biomarkers and Therapies

    • 1st Edition
    • Volume 161
    • English
    Current Status of Prostate Cancer: Diagnosis, Biomarkers and Therapies, Volume 161 in the Advances in Cancer Research series, covers timely topics such as The Prostate Cancer Tissue N-glycome as a Source of Biomarkers, a Progression from Normal to Metastatic Disease, Multiplexed Targeted Proteomics for Prostate Cancer Biomarker Verification, MRI for the Detection of Clinically Significant Prostate Cancer: Update and Future Directions, Genetic and epigenetic factors for prostate cancer progression, Epigenetic regulation of androgen dependent and independent prostate cancer, Molecular Landscape of Prostate Cancer Bone Metastasis, Future of radioligand Therapy in PC, and more.Additional chapters of note include Advancements in Computer Vision and Pathology: Unraveling the Potential of Artificial Intelligence for Precision Diagnosis and Beyond and Extracellular Vesicles in Prostate Cancer.

  • Circuits, Signals, and Systems for Bioengineers

    A MATLAB-Based Introduction
    • 4th Edition
    • John Semmlow
    • English
    Circuits, Signals, and Systems for Bioengineers: A MATLAB-Based Introduction, Fourth Edition, guides the reader through the electrical engineering principles that can be applied to biological systems. It details the basic engineering concepts that underlie biomedical systems, medical devices, biocontrol, and biomedical signal analysis, providing a solid foundation for students in important bioengineering concepts. Fully revised and updated to better meet the needs of instructors and students, the fourth edition expands on concepts introduced in the previous edition through computational methods that allow students to explore operations, such as correlations, convolution, the Fourier transform, and the transfer function. New medical examples and applications are included throughout the text.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 85
    • English
    Advances in Microbial Physiology, Volume 85 in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Topics of interest in this update include The genetic basis of predation by myxobacteria, Vancomycin susceptibility and VISA in Staphylococcus aureus, Cytochrome bd-type oxidases and environmental stressors in microbial physiology, Bacterial heme-containing sensor proteins, Algal hemoglobins, Inter-species interactions in polymicrobial infections, Utilization of Low Methane Concentrations by Methanotrophs, and Role of sulfidogenic members of the gut microbiota in human disease.

  • The Discovery of New Medicines in Academia

    • 1st Edition
    • Volume 100
    • English
    The Discovery of New Medicines in Academia, Volume 100 highlight examples of discoveries originating in academia that have been successfully translated into promising therapeutics that have advanced into clinical trials. Chapters in this release cover Design and Discovery of Itaconate prodrugs for Alopecia Areata, Hydroxyl-Dendrimer Delivery System for Neurological Disease, Development of allosteric modulators of G protein-coupled receptors for Psychiatric Disease, Targeting the constitutively active ERK1/2 signaling kinase for cancer, mRNA reprogramming of myeloid cells for tumor immunotherapy, Development of novel drugs targeting protein-protein interactions, and much more.Additional sections cover Neuro-steroids and analogs for the treatment of epilepsy, Development of inhibitors of eukaryotic translation, Discovery/developmen... of antiviral, anticancer and/or anti-inflammatory agents, Discovery of novel anti-infective agents, Targeting proliferating cell nuclear antigen (PCNA) for cancer, and Implementation and Evolution of Quantitative Systems Pharmacology to Patient Digital Twins and Biomimetic Twins.

  • Advances in Agronomy

    • 1st Edition
    • Volume 187
    • English
    Advances in Agronomy, Volume 187, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Targeted Genome Engineering via CRISPR/Cas9 in Plants

    • 1st Edition
    • Alvina Gul
    • English
    Targeted Genome Engineering via CRISPR/Cas9 in Plants provides in-depth insights into the use of the emerging “CRISPR/Cas9” technology for precise genome editing. This technology has revolutionized plant science research particularly for crop improvement owing to its simplicity and efficiency. The book provides a wide range of CRISPR/Cas9 gene editing techniques for a variety of plants. Chapters include the latest applications of CRISPR/Cas9 system in connection with abiotic stresses, biotic stresses, biofortification, yield improvement, disease modelling and prognosis and molecular diagnosis. Targeted Genome Engineering via CRISPR/Cas9 in Plants also evaluates various regulatory and ethical aspects that must be considered when implementing the CRISPR/Cas9 approach. This book is a valuable resource for professionals and researchers, as it provides effective CRISPR/Cas9-based strategies for sustainable agriculture and treatment of various diseases.

  • The Neurophysiology of Silence (C): Creativity, Aesthetic Experience and Time

    • 1st Edition
    • Volume 287
    • English
    Neurophysiology of Silence: Consciousness and Self Awareness, Volume 284 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Hormones and Reproduction of Vertebrates, Volume 1

    Fishes
    • 2nd Edition
    • David O. Norris + 1 more
    • English
    Hormones and Reproduction of Vertebrates, Volume 1: Fishes is the first of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book includes coverage of endocrinology, neuroendocrinology, physiology, behavior, and anatomy of fish reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. New to this edition is a concluding assessment of the effect of environmental influences on fishes.Initial chapters in this book broadly examine sex determination, reproductive neuroendocrinology, stress, and hormonal regulation as they relate to testicular and ovarian development and function. Subsequent chapters examine hormones and reproduction of specific taxa, especially teleosts, with additional coverage of reproductive cycles of agnathan, chondrichthyan, and sarcopterygian fishes. The book concludes with an examination of the environmental influences on hormones and reproduction of fishes, including endocrine-disrupting chemicals, microplastic particles, and climate change.

  • Diagnosis and Analysis of COVID-19 using Artificial Intelligence and Machine Learning-Based Techniques

    • 1st Edition
    • Mohammad Sufian Badar + 4 more
    • English
    Diagnosis and Analysis of COVID-19 using Artificial Intelligence and Machine Learning-Based Techniques offers new insights and demonstrates how machine learning (ML), artificial intelligence (AI), and (Internet of Things (IoT) can be used to diagnose and fight COVID-19 infection. Sections also discuss the challenges we face in using these technologies. Chapters cover pathogenesis, transmission, diagnosis, and treatment strategies for COVID-19, Artificial Intelligence and Machine Learning, and Blockchain /IoT Blockchain technology, examining how AI can be applied as a tool for detection and containment of the spread of COVID-19, and on the socioeconomic and educational post-pandemic impacts of the disease.This is a multidisciplinary resource for those engaged in researching COVID-19 and how emerging technologies are being used as tools for detection, transmission and treatment strategies.

  • Biophysical Approaches for the Study of Membrane Structure Part B

    • 1st Edition
    • Volume 701
    • English
    Biophysical Approaches for the Study of Membrane Structure, Part B, Volume 701 explores lipid membrane asymmetry and lateral heterogeneity. A burst of recent research has shown that bilayers whose leaflets differ in their physical properties—such as composition, phase state, or lateral stress—exhibit many fascinating new characteristics, but also pose a host of challenges related to their creation, characterization, simulation, and theoretical description. Chapters in this new release include Characterization of domain formation in complex membranes: Analyzing the bending modulus from simulations of complex membranes, The density-threshold affinity: Calculating lipid binding affinities from unbiased Coarse-Grain Molecular Dynamics simulations, and much more.Additional sections cover Uncertainty quantification for trans-membrane stresses and moments from simulation, Using molecular dynamics simulations to generate small-angle scattering curves and cryo-EM images of proteoliposomes, Binary Bilayer Simulations for Partitioning Within Membranes, Modeling Asymmetric Cell Membranes at All-atom Resolution, Multiscale remodeling of biomembranes and vesicles, Building complex membranes with Martini 3, Predicting lipid sorting in curved bilayer membranes, Simulating asymmetric membranes using P21 periodic boundary conditions, and many other interesting topics.

  • Cannabidiol in Neurology and Psychiatry

    • 1st Edition
    • Volume 177
    • English
    Cannabidiol in Neurology and Psychiatry, Volume 177 in the International Review in Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topic such as Historical perspective on the therapeutic potential of cannabidiol, Cannabidiol: pharmacodynamics pharmacokinetic, Cannabidiol and Alzheimer’s disease, Cannabidiol on anxiety disorders, Cannabidiol on psychosis, Cannabidiol on autism spectrum disorders, Cannabidiol in Epilepsy, Cannabidiol in Ischemia/stroke, Cannabidiol in Depression, Cannabidiol and Abuse of drugs, and much more.Additional chapters cover Cannabidiol in fear response and PTSD, Cannabidiol and Pain. and Cannabidiol and Parkinson’s disease.

  • Blood-Brain Barrier

    • 1st Edition
    • Volume 126
    • English
    Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Hormones and Reproduction of Vertebrates, Volume 2

    Amphibians
    • 2nd Edition
    • David O. Norris + 1 more
    • English
    Hormones and Reproduction of Vertebrates, Volume 2: Amphibians is the second of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book covers endocrinology, neuroendocrinology, physiology, behavior, and the anatomy of amphibian reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. New to this edition is a concluding assessment of the effect of environmental influences on amphibians.This book is designed to provide a readable, coordinated description of reproductive basics in amphibians, as well as an introduction to the latest trends in reproductive research and a presentation of our understanding of reproductive events gained over the past decade. It may serve as a stand-alone reference for researchers and practitioners in the field of herpetology or as one of five coordinated references aligned to provide topical treatment across vertebrate taxa for researchers, practitioners, and students focused on vertebrate endocrinology.

  • Personalized Epigenetics

    • 2nd Edition
    • Trygve Tollefsbol
    • English
    Personalized Epigenetics, Second Edition discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy. Fully updated and revised, this new edition details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, noncoding RNA, and the diagnostic, prognostic, and therapeutic potential of the field. It also reviews the impact of the environment on epigenetic variations among individuals and the role of pharmacology and drug development in personalized epigenetics.Most importantly, the text covers personalized epigenetics from a disease-oriented perspective, presenting chapters that provide advances in widespread disorders or diseases, including diabetes, cancer, autoimmune disorders, obesity, cardiovascular diseases, neurological disorders, and pain management.

  • Aquaculture Virology

    • 2nd Edition
    • Frederick S.B. Kibenge + 1 more
    • English
    In 2018, the International Committee on Taxonomy of Viruses (ICTV) approved significant changes leading to a comprehensive taxonomic scheme, allowing the global organization of the virus world (also known as virus megataxonomy). Aquaculture Virology, Second Edition updates the current knowledge on aquatic animal viruses so that all virus families (including those with many newly discovered aquatic animal viruses and those with previously unclassified aquatic animal viruses that have been now assigned) are available under one cover, increasing the number of book chapters from 37 in the first edition to 44 chapters in the second edition. The aims, philosophy, target audience, focus, and format of this second edition of Aquaculture Virology remain unchanged. Like the first edition, this book is a systematic and concise resource useful to anyone involved with or looking to move into aquaculture and fisheries. Clinical veterinarians, aquaculture disease practitioners, biologists, farmers, and all those in industry, government, or academia interested in aquatic animal virology will find this book extremely useful.

  • Overcoming Cancers Resistant to HER-2 Antibodies

    • 1st Edition
    • Volume 2
    • Benjamin Bonavida
    • English
    Overcoming Cancers Resistant to HER-2 Antibodies provides general updated information on the resistance of various human cancers to anti-HER2 therapeutic antibodies. The book also discusses the description of various sensitizing agents that can reverse resistance when used in combination with anti-HER2 antibodies. There have been a lot of reports in which the treatment with anti-HER2 antibodies for various cancers has resulted in clinical responses; however, there have been also subsets of cancer patients who did not respond initially, and several responding patients developed resistance following treatments. Sections cover Lapatinib, Ganetespib, Paclitaxel, Celecoxib, Emantasine, Liposomal Doxorubicin, and Kinase Inhibitors.This book is a valuable source for cancer researchers, oncologists, pharmacologists and different members of the biomedical field interested in fighting cancer resistance to HER-2 antibodies.

  • Pigmented Grains

    Nutritional Properties, Bioactive Potential, and Food Application
    • 1st Edition
    • Arashdeep Singh + 3 more
    • English
    Pigmented Grains: Nutritional Properties, Bioactive Potential, and Food Application highlights the potential of pigmented grains crops in the human diet and their health benefits due to presences of the rich source of phytochemicals and pigments. Divided into 13 chapters, the book covers the breeding approaches and techniques for producing pigmented grains, the functionality and nutritional properties of wheat, rice, maize, barley, oats and rye, sorghum, millets, and pseudo cereals such as amaranth, quinoa and buckwheat. Others chapters cover the processing of pigmented grains and the effect on their functionality, utilization of pigmented grains and their by-products This is a comprehensive reference written for teachers, scientists, researchers, students, and all others who have interest in pigmented grains their potential nutritional value, utilization in food processing, value addition, and in combating malnutrition and nutritional security.

  • Enzyme Biotechnology for Environmental Sustainability

    • 1st Edition
    • Praveen Dahiya + 2 more
    • English
    Enzyme Biotechnology for Environmental Sustainability discusses recent applications of enzyme biotechnology in various industrial sectors and state-of-the-art information on novel microbial enzyme technologies for a sustainable environment.The book describes in detail the latest developments and modern methods in microbial enzyme biotechnology for wider application in bioremediation, cleaner technology for industries and waste management, green chemistry and pharmaceutical biotechnology, sustainable textiles, food production and biodegradation, and other industries. The chapters cover topics such as genetic engineering, protein engineering, nanotechnological advances of microbial enzymes, computational tools for engineering enzymes, and health risk assessment of enzymes in different sectors. With contributors from an array of experts in the field, Enzyme Biotechnology for Environmental Sustainability is an informative reference for researchers, biotechnologists, microbiologists, environmental scientists, graduate and post-graduate students working in the area of enzyme technology and their biomedical, environmental, and industrial applications.

  • The Immunology of the Dog

    • 1st Edition
    • Ian R. Tizard
    • English
    The Immunology of the Dog is the first readily available, single-source, comprehensive review of the canine immune system. The book discusses all immunologic aspects of diseases of the dog and relates recent basic science to important clinical issues. Sections cover the evolution and domestication of the dog, provide detailed information on immunity to infectious diseases, canine allergic diseases, the top canine autoimmune diseases, and canine immunodeficiencies. This book offers professionals in veterinary research and practice complete information on all aspects of canine immunology in one essential resource.

  • Nanostructured Drug Delivery Systems in Infectious Disease Treatment

    • 1st Edition
    • Sarwar Beg + 4 more
    • English
    Nanostructured Drug Delivery Systems in Infectious Disease Treatment explores a broad range of promising approaches for the treatment of infectious diseases using the latest advancements in nanomedical technologies. The book opens with an introduction about infectious diseases and global burdens. There is also specific discussion and assessment of the global impact of viruses with an emphasis on COVID-19, Zika, and Ebola. Subsequent chapters provide detailed information about various novel nanotherapeutic strategies used for delivering drugs for the treatment of various types of viral, bacterial, and fungal disorders. This will be a valuable resource for graduates, researchers, industry professionals, and anyone working to tackle the challenges of delivering drugs in a more targeted and efficient manner for the treatment of infectious diseases.

  • Edible Flowers

    Health Benefits, Nutrition, Processing, and Applications
    • 1st Edition
    • Arun Kumar Gupta + 3 more
    • English
    Edible Flowers: Health Benefits, Nutrition, Processing, and Applications discusses several edible flowers and their history, bioactive compounds, pharmacological properties, chemistry, and manifold applications. Composed of 20 chapters, the book explores significant edible flowers which have a bioactive and pharmacological attribute apart from preservation aspects. Each of the presented flowers are analyzed by its taxonomy, history, nutritional properties, important bioactive natural compounds, pharmacological potential, use in food processing, and marketability.Medici... and edible flowers that are grown in the various countries and are thought to promote health are also the subject of this book, thus ensuring the food security aspect. Written by a team of experts in the field, this book is a good support for researchers and scientists working in the fields of food science, food technology, and nutrition, with a special interest by the study of edible flowers.

  • Metaverse Technologies in Healthcare

    • 1st Edition
    • Rajesh Kumar Dhanaraj + 4 more
    • English
    Metaverse Technologies in Healthcare focuses on data analysis, utilizing the possibilities of data to increase the effectiveness of healthcare organizations. As healthcare services aim to maintain the physical, mental, social and emotional well-being of human lives while the Metaverse is a blend of technological trends- Artificial Intelligence (AI), Augmented Reality (AR) and Virtual Reality (VR), collectively, they can deliver treatments and medicines, lower costs, and substantially enhance patient outcomes. The book redefines the digital health experience and describes the advantages of the Metaverse-based NFT technology in the healthcare sector, facilitating NFT avatars to interact with targeted audiences, and more.

  • Glycation

    • 1st Edition
    • Volume 125
    • English
    Glycation, Volume 125 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Nutritional and Health Aspects of Food in Western Africa

    • 1st Edition
    • Ogugua Charles Aworh + 1 more
    • English
    Nutritional and Health Aspects of Native West African Foods is part of an ongoing series that continues to build out Elsevier’s Nutritional and Health Aspects of Traditional and Ethnic Foods series. Written by a gender diverse team of experts, this book explores native and wild West African foods from Cameroon, Ghana, and Nigeria where 60% of West Africa live. Through valorization trials, the book analyzes nutritional components and the processing and safety of native plants and botanicals and shows how indigenous foods such as grains, fruits, tubers, fungi and cheese make a global impact on diet-related health claims and disease.From handling and processing methods to regulatory issues and sustainable farming, this book presents a framework to discover the influence of historical eating habits on today’s diets.

  • Vegetation Dynamics and Crop Stress

    An Earth-Observation Perspective
    • 1st Edition
    • Dipanwita Dutta + 2 more
    • English
    Vegetation Dynamics and Crop Stress: An Earth-Observation Perspective focuses on vegetation dynamics and crop stress at both the regional and country levels by using earth observation (EO) data sets. The book uniquely provides a better understanding of natural vegetation and crop failure through geo-spatial technologies. This book covers biophysical control of vegetation, deforestation, desertification, drought, and crop-water efficiency, as well as the application of satellite-derived measures from optical, thermal, and microwave domains for monitoring and modeling crop condition, agricultural drought, and crop health in contrasting monsoon/weather episodes.

  • Genetics and Evolution of Infectious Diseases

    • 3rd Edition
    • Michel Tibayrenc
    • English
    Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens.Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases.

  • Internet of Things and Machine Learning for Type I and Type II Diabetes

    Use cases
    • 1st Edition
    • Sujata Dash + 4 more
    • English
    Internet of Things and Machine Learning for Type I and Type II Diabetes: Use Cases provides a medium of exchange of expertise and addresses the concerns, needs, and problems associated with Type I and Type II diabetes. Expert contributions come from researchers across biomedical, data mining, and deep learning. This is an essential resource for both the AI and Biomedical research community, crossing various sectors for broad coverage of the concepts, themes, and instrumentalities of this important and evolving area. Coverage includes IoT, AI, Deep Learning, Machine Learning and Big Data Analytics for diabetes and health informatics.

  • Sleep and Sport

    Physical Performance, Mental Performance, Injury Prevention, and Competitive Advantage for Athletes, Coaches, and Trainers
    • 1st Edition
    • Michael A. Grandner + 1 more
    • English
    **Selected for 2025 Doody’s Core Titles® in Sports Medicine**The relationship between sleep and both mental and physical performance in athletes has become a key issue over the past several years. Sleep and Sport: Physical Performance, Mental Performance, Injury Prevention, and Competitive Advantage for Athletes, Coaches, and Trainers aims to synthesize the growing scientific evidence in this area to help researchers, clinicians, and others interested in sport to understand the fundamentals of sleep health and how these factors relate to athletes. Serving as an important bridge between the sleep and athletics field, this book educates sleep professionals about how their field of expertise relates to various aspects of athletics, while educating sports professionals about the basics of sleep and how it relates to their field of expertise. This is accomplished by explaining some of the basics of sleep health; reviewing the literature on sleep disorders, treatments, and risk factors for athletes; discussing ways that sleep health impacts physical and mental performance; and addressing key specific areas where these fields overlap. In all cases, this text will draw from the existing peer-reviewed literature, in order to provide evidence-based guidance that is objective and well explained.

  • Reverse Vaccinology

    Concept, Methods and Advancement
    • 1st Edition
    • Jayashankar Das + 3 more
    • English
    Reverse Vaccinology: Concept, Methods, and Advancement presents the development strategy of new vaccines through genome sequencing bioinformatics analysis. This book promises to revolutionize vaccine development, especially for pathogens to which the classical applications of Pasteur’s principles have failed, and it is explained in detail in this book.This book is split into three sections: the first, Concept, brings the basis of reverse vaccinology, vaccine antigen discovery, and subunit vaccine; the second, Tools and Methods, describes immunoinformatic, proteomics for epitope-vaccine design, databases, network analysis, machine learning, and NGS-driven antigen screening technology; and the last one, Disease Case Study, discusses real-world examples in the development of new vaccines for diverse diseases.It is a valuable resource for bioinformaticians, researchers, students, and members of the biomedical and medical fields who want to learn more about a new and agile process for the development of new vaccines.

  • Metalloproteins and Motor Proteins

    • 1st Edition
    • Volume 141
    • English
    Metalloproteins and Motor Proteins, Volume 141 focuses on recent advances in studying metalloproteins and motor proteins, along with their roles in different pathologies and drug-resistance. Chapters include Transcriptomic Analysis Reveals Zinc-Mediated Virulence and Pathogenicity in Multidrug-Resistant Acinetobacter baumannii, The Mechanistic Insights into Different Aspects of Promiscuity in Metalloenzymes, Role of Metal ion in ion channel Mechanisms, A model of microtubule depolymerization by kinesin-8 motor proteins, Metalloproteins and metalloproteomics in health and disease, Decoding Genetic and Pathophysiological Mechanisms in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis: A Comparative Study of Differentially Expressed Genes and Implicated Pathways in Motor Neuron Disorders, and much more.Additional chapters cover Exploring the effect of disease causing mutations in metal binding sites of human ARSA in Metachromatic Leukodystrophy, Role of transmembrane proteins in regulating metalloproteins and motor proteins in human cancer, Role of transmembrane proteins in metalloproteins and motor proteinsin human neurogenesis, Role of transmembrane proteins in metalloproteins and motor proteins in human aging, Vesicle transport of metalloproteinases, Motor proteins and spermatogenesis, and much more.

  • Biophysical Approaches for the Study of Membrane Structure Part A

    • 1st Edition
    • Volume 700
    • English
    Biophysical Approaches for the Study of Membrane Structure, Part A, Volume 700 explores lipid membrane asymmetry and lateral heterogeneity. A burst of recent research has shown that bilayers whose leaflets differ in their physical properties—such as composition, phase state, or lateral stress—exhibit many fascinating new characteristics, but also pose a host of new challenges related to their creation, characterization, simulation, and theoretical description. Chapters in this new release include Evaluation of functional transbilayer coupling in live cells by controlled lipid exchange and imaging FCS, Effects of lateral and hydrostatic pressure on membrane structure and properties, and much more.Other sections cover Using the yeast vacuole as a system to test the lipid drivers of membrane heterogeneity in living cells, Direct quantification of cellular membrane lipids using ratiometric fluorescence sensors, The spectral phasor approach to resolving membrane order with environmentally sensitive dyes, The use of hemifusion to create asymmetric giant unilamellar vesicles: Insights on induced order domains, Advanced microscopy methods to study membrane pores, Use of cryo-EM to study membrane phase separation, and much more.

  • Recent Trends in Fractional Calculus and Its Applications

    • 1st Edition
    • Praveen Agarwal + 2 more
    • English
    Recent Trends in Fractional Calculus and Its Applications addresses the answer to this very basic question: "Why is Fractional Calculus important?" Until recent times, Fractional Calculus was considered as a rather esoteric mathematical theory without applications, but in the last few decades there has been an explosion of research activities on the application of Fractional Calculus to very diverse scientific fields ranging from the physics of diffusion and advection phenomena, to control systems to finance and economics. An important part of mathematical modelling of objects and processes is a description of their dynamics.The term Fractional Calculus is more than 300 years old. It is a generalization of the ordinary differentiation and integration to noninteger (arbitrary) order. The subject is as old as the calculus of differentiation and goes back to times when Leibniz, Gauss, and Newton invented this kind of calculation. Several mathematicians contributed to this subject over the years. People like Liouville, Riemann, and Weyl made major contributions to the theory of Fractional Calculus. In recent decades the field of Fractional Calculus has attracted the interest of researchers in several areas, including mathematics, physics, chemistry, engineering, finance, and social sciences.

  • Multiple Sclerosis and Associated Demyelinating Disorders, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 34-3
    • Frederik Barkhof + 1 more
    • English
    In this issue of Neuroimaging Clinics, guest editors Drs. Frederik Barkhof and Yaou Liu bring their considerable expertise to the topic of Multiple Sclerosis and Associated Demyelinating Disorders. Top experts in the field discuss advanced brain imaging in CNS demyelinating diseases; new imaging markers in MS and related disorders: smoldering inflammation and central vein sign; the use of AI in MS and white matter disease; optic nerve imaging in MS and related disorders; atypical demyelinating disorders; and more. Co-Editor Frederik Barkhof, MD, has received the National Multiple Sclerosis Society and the American Academy of Neurology’s 2018 John Dystel Prize for Multiple Sclerosis Research for his many years of outstanding research in the field of MS, especially in advancing the understanding and clinical use of brain imaging.

  • Design and Applications of Microneedles in Drug Delivery and Therapeutics

    • 1st Edition
    • Prashant Kesharwani
    • English
    Design and Applications of Microneedles in Drug Delivery and Therapeutics details the design, characterization, and applications of this novel drug delivery system. Microneedles offer several advantages over traditional oral and parenteral approaches due to their ability to be fabricated and altered in shape, size and material type, and their convenience to be matched to specific treatment needs. This book covers the materials selection, design and fabrication approaches, and clinical translation of microneedles for a range of therapeutic applications, including cancer therapy, gene and vaccine delivery, wound healing, and more.This book is a forward-thinking resource for those working in the development of materials and devices for novel drug delivery.

  • Clinical Application of Repurposed Drugs

    • 1st Edition
    • Volume 207
    • English
    Clinical Application of Repurposed Drugs, Volume 207 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on Drug repurposing for viral disease, Drug repurposing for bacterial infections, Drug repurposing for parasitic protozoan diseases, Drug repurposing for fungal infections, Drug repurposing for treating anxiety and depression, Drug repurposing for personalized medicine, Drug repurposing for cancer, Drug Repurposing: A multi targeted approach to treat cardiac disease from existing classical drugs to modern drug discovery, and much more.Additional chapters cover Drug repurposing in MASLD and MASH-cirrhosis: targets and treatment approaches based on pathways analysis, Drug repurposing for respiratory infections, Drug repurposing for rare disease, Drug repurposing for neurological disorders, Drug repurposing for metabolic disorders: scientific, technological and economic issues, Drug repurposing for regenerative medicine and cosmetics: scientific, technological and economic issues, and Exploring Cutting-Edge Omics-Driven Strategies for Drug Repurposing – An Insight into the Tools of the Trade.

  • Terpene Synthases

    • 1st Edition
    • Volume 699
    • English
    Terpene Synthases, Volume 700 in the Methods in Enzymology series, continues the legacy of this highly respected laboratory standard with its first dedicated collection on this important family of enzymes. Terpene synthases are a diverse set of enzymes that use exquisite mechanisms to form complex (poly)cyclic hydrocarbon skeletons. Chapters in this new volume include Structural analysis by X-ray crystallography and cryo-EM, Understanding mechanisms using stable isotopes, substrate analogs, or computational tools, Engineering fusion enzymes, Ancestral terpene cyclases, as well as the Sequence, structure, and function of non-canonical terpene synthases.

  • Prosopis Juliflora

    Attributes, Impact, Utilization
    • 1st Edition
    • Pratiksha Patnaik + 2 more
    • English
    Prosopis (Prosopis juliflora) is a xerophyte which, in its native habitats has been a desert plant. As long as it was confined to that habitat, P. juliflora was a great resource, improving the region’s micrometeorology, binding its sandy soil, and providing shelter, fuel, feed, food, medicines, and cosmetics to the people of such regions. In particular, for the economically weaker inhabitants, P.juliflora was a lifeline.But when P. juliflora was indiscriminately introduced in other regions of the world in a hope to derive similar benefits from it, things began to go awry. Indeed, among the invasive species of plants which are spreading at an alarming rate in the tropical and sub-tropical regions of the world, P.juliflora is arguably the most hardy and resilient. It is growing so explosively that it even enters roads and homes, driving humans out of their dwellings. The resulting damage to biodiversity is enormous. This book highlights the dual role played so far by P. juliflora and itemizes the facets that make it a blessing in some contexts and a bane in other contexts.Authored by leading experts in the field, Prosopis juliflora: Attributes, Impact, Utilization is the first title of its kind to comprehensively discuss this hardy plant species. It will be an essential read for students, researchers and governmental agencies interested in plant biology, forestry, plant ecology, invasive plant species and environmental science.

  • Peritoneal Tumor Microenvironment of Cancers on Cancer Hallmarks

    Perspectives of Translational Medicine
    • 1st Edition
    • Yong Sang Song + 6 more
    • English
    Peritoneal Tumor Microenvironment of Cancers on Cancer Hallmarks: Perspectives of Translational Medicine provides readers with cutting-edge knowledge on tumor microenvironment. By exploring multiple aspects on tumor microenvironment, it gives an integrative insight on cancer diseases ranging from diagnosis to prediction of prognosis and individualized treatment. The book discusses topics such as clinical significance of tumor microenvironment, tumorigenesis and cancer progression, histopathological features of cancer in peritoneum, immune cells in tumor, exosomal cell-to-cell interactions, and therapeutic approaches to target tumor microenvironment. In addition, it discusses tumor evolution during chemotherapy and metastasis and future perspectives on identification and validation of biomarkers using liquid biopsy. This book is a valuable resource for cancer researchers, oncologists, medical doctors, and several members of biomedical field who want to understand the complex microenvironment of peritoneal tumors.

  • Evolving Landscape of Molecular Diagnostics

    Applications and Techniques
    • 1st Edition
    • Mrutyunjay Suar + 2 more
    • English
    Evolving Landscape of Molecular Diagnostics: Applications and Techniques presents cutting-edge reviews on current and emerging technologies in the diagnosis of microbial infections. The book discusses the fundamentals of Molecular Diagnostics for bacteria, fungi, viruses and a variety of state-of-the-art diagnostics tools and techniques for obtaining qualitative and quantitative results. It includes topics such as Next generation sequencing and application of "OMICS" for early disease diagnosis. Sections cover the entire spectrum of emerging diagnostic tools and techniques, as well as the principles, pros and cons of each method and applications for diagnosis of infectious disease in plants, humans and veterinary. This is a resource for both researchers and students working in clinical microbiology, infectious biology, applied life sciences and scientists working in the clinical diagnostic industry.

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