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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Encyclopedia of the Neurological Sciences

    • 3rd Edition
    • John D. England
    • English
    Major advances in neurobiology and the clinical neurosciences have occurred in the past decade. Encyclopedia of the Neurological Sciences, Third Edition, Seven Volume Set, will cover and review all major areas of neuroscience and will be one of the few publications that can provide a complete overview of the neurological sciences in an easily accessible electronic format. All 21 sections and approx. 500 chapters will contain extensive supplemental links to useful references. Of special note are the new and paradigm shifting developments in genetics, immunology, molecular neurobiology, neuro-diagnostic tools and therapies for neurological disorders. This new edition will provide a thorough and easily accessible update in all areas of the neurological sciences. The sections and chapters will be written by internationally recognized experts from around the world and will be a valuable resource for all researchers, students and established scientists in the fields of neurology, psychiatry, and neurosurgery.

  • Developmental Dyscalculia

    From Brain Mechanisms to Educational Applications
    • 1st Edition
    • Yarden Gliksman + 2 more
    • English
    Developmental Dyscalculia: From Brain Mechanisms to Educational Applications presents research with a domain-general approach. It examines issues in the fields of numerical and non-numerical cognitive domains, neuro- mechanisms, and pedagogic issues to pave the way to a bridge between lab research, daily life, and curriculum applications, with a goal of finding a pathway to early diagnosis and interventions of developmental dyscalculia. It will be of interest to researchers with interests in cognitive neuroscience and education, to contribute fruitful discussions between education and neuro-cognition. 

  • Psychopharmacologie pratique

    Transposer les résultats des essais fondés sur les preuves dans la pratique clinique
    • 1st Edition
    • Joseph F. Goldberg + 2 more
    • French
    Aujourd’hui, la polypharmacologie est un outil majeur pour le traitement des patients souffrant de formes graves et chroniques de troubles de l’humeur, d’anxiété, de psychose ou de troubles du comportement.Dans l’esprit des travaux et écrits de Stephen M. Stahl, cet ouvrage offre une vue d’ensemble novatrice sur les connaissances en psychopharmacologie et les stratégies de prises de décision, en intégrant les résultats d’essais fondés sur les preuves aux données de la clinique, avec des exemples et des situations cliniques réelles. Il aborde la manière dont les prescripteurs peuvent mettre en place une « psychopharmacologie sur mesure », adaptée aux besoins spécifiques de chaque patient, en conservant l’approche et l’état d’esprit d’un praticien.Quelle que soit leur expérience, les professionnels pourront ainsi affiner et améliorer leurs prescriptions et leurs prises en charge, en ciblant les manifestations des circuits neuronaux dysfonctionnels et les dimensions psychopathologiques, au-delà des diagnostics psychiatriques conventionnels.Prése... sous une forme dynamique, pratique et en couleurs, avec des tableaux de synthèse, des encadrés et des vignettes cliniques concrètes, cet ouvrage est un guide précieux d’aide à la décision pour tous les praticiens qui prescrivent des psychotropes. Joseph F. GoldbergProfesseur de psychiatrie clinique,Icahn School of Medicine at Mount Sinai, New YorkStephen M. StahlProfesseur de psychiatrie et de neurologie,Universit... of California Riverside and University of California San DiegoMarc-Antoine Crocq (traducteur)Psychiat... des adolescents du Haut-Rhin, CAMUHA,Université de Haute-Alsace, Mulhouse

  • The Neuroscience of Feelings

    Unveiling the Mind-Brain Alchemy
    • 1st Edition
    • Volume 293
    • English
    The Neuroscience of Feelings: Unveiling the Mind-Brain Alchemy focuses on exploring the complex interplay between emotions and brain function, covering topics such as how positive and negative feelings impact brain cell regeneration, the influence of emotions on decision-making, and the role of emotional trauma in brain health. The book aims to provide comprehensive insights into how different emotions shape neurological processes, contributing to mental and physical health.

  • Microbiome in Neurological Conditions: Biology, Mechanisms, and Diagnostic Approach

    • 1st Edition
    • Volume 180
    • English
    Microbiome in Neurological Conditions, Volume 180, the latest release in the International Review of Neurobiology series, highlights advances in the field, with this volume presenting insightful chapters written by an international board of authors. Chapters in this volume include Dysbiosis significantly elevates the probability of altered affective function in Alzheimer's Disease (AD), Intestinal Dysbiosis leads to reduction in Neurochemical production in Parkinson’s Disease (PD), Microbiota dysbiosis impact on the immune system dysregulation in Huntington's disease (HD), Altered microbiome influence on the enteric neuromuscular system in Amyotrophic Lateral Sclerosis (ALS), Oro-pharyngeal mucosal microbiome alterations causing immune system dysregulation in Schizophrenia, and much more.Other chapters cover Disruption in the human microbiome causing behavioral changes in Bipolar Disorder, The role of Microbiome in Gut-Brain-Axis dysbiosis causing Depression: from Mechanisms to Treatment, Microbial imprints: The role of secondary genomes in neurodevelopment and co-evolutionary dynamics, Abnormal microbiota due to perinatal antibiotic exposure as a possible risk factor for Attention-Deficit / Hyperactivity Disorder (ADHD), Microbiome-based dietary supplements for better development and a healthy brain, Bacterial meningitis as a significant catalyst for neuroinflammation, and more.

  • Music and Dementia

    Theory and Implications for Music Use in Dementia Care
    • 1st Edition
    • Sandra Garrido
    • English
    Music and Dementia: Theory and Implications for Music Use in Dementia Care presents research on the effect of music on the brain for neurodegenerative diseases and care. This volume examines the neurological impact of music from research to clinical application, offering case studies and practical steps. This book will be of interest to researchers in dementia and neurodegeneration, as well as practitioners and clinicians interested in the therapeutic application of music in dementia care.

  • Encyclopedia of the Eye

    • 2nd Edition
    • Patricia D’Amore
    • English
    Encyclopedia of the Eye, Second Edition, Four Volume Set is an important resource for all visual scientists, ophthalmologists, and optometrists, as well as researchers in immunology, infectious disease, cell biology, neurobiology, and related disciplines. This four-volume reference is unique in its coverage of information on all tissues important for vision, including the retina, cornea, and lens. The book also covers the physiological and pathophysiologic processes that affect all eye tissues. Each chapter addresses one specific structure or process, reviews basic concepts, cross-references other chapters within the Encyclopedia, and provides citations of relevant primary publications.It is an invaluable resource for undergraduate students, graduate students, postdoctoral fellows, medical students, and residents seeking an introduction to an area of eye research. It will be particularly useful for visual scientists and practitioners who are investigating a new area, seeking deeper understanding of important research articles in fields adjacent to their own, and/or reviewing a grant or manuscript outside their immediate area of expertise.

  • Blindness and Visual Impairments

    • 1st Edition
    • Volume 292
    • English
    Blindness, Volume 292 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Temperature as a circadian timing cue in the visually impaired, Visual experience affects neural correlates of audio-haptic integration: A case study of non-sighted individuals, Visual experience affects neural correlates of audio-haptic integration: A case study of non-sighted individuals, Measuring residual visual function after cerebral damage – a potential path for optimizing rehabilitation approaches, and Persistence of training-induced visual improvements after occipital stroke, amongst other topics.Other chapters in this release include Well-being, mental health, and sleep in children and young people with vision impairment: A narrative review, Changes to the brain due to visual impairment, Information Processing in People with Visual Impairments, Case studies of the migraine aura in the blind or partially sighted, HABEMO: an innovative haptic tool for investigating the bodily representation of mental states in individuals with visual impairments, and Affect in the dark: navigating the complex landscape of social cognition in blindness, and An overview of quality of life and visual outcomes in AMD.

  • Parkinson's Disease, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 43-2
    • Joseph Jankovic
    • English
    In this issue of Neurologic Clinics, guest editor Dr. Joseph Jankovic brings his considerable expertise to the topic of Parkinson's Disease. Top experts cover key topics in the field, including James Parkinson and other historical aspects of Parkinson’s disease; precision medicine in Parkinson’s disease; prodromal Parkinson’s disease; biomarkers in Parkinson’s disease; disease-modifying therapies in Parkinson’s disease; and many more.

  • Cholinergic Involvement in Neurodegenerative Diseases

    • 1st Edition
    • Volume 211
    • A. Claudio Cuello
    • English
    Cholinergic Involvement in Neurodegenerative Diseases, Volume 211 reviews cholinergic function in the brain as it relates to Neurodegenerative disorders. Coverage includes Alzheimer’s, dementia, Down Syndrome, Parkinson’s, Huntington’s, ALS, and more. In addition, the anatomy of the cholinergic system is described as well as the distribution and function of receptors.

  • Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies

    • 1st Edition
    • Volume 291
    • English
    Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies is a comprehensive exploration of how stress affects the brain at a molecular level and its broader implications for mental and neurological health. The book delves into the mechanisms by which stress triggers changes in brain function, including the activation of the hypothalamic-pituita... (HPA) axis, synaptic plasticity alterations, oxidative stress, neuroinflammation, and mitochondrial dysfunction. It examines how these molecular processes contribute to conditions such as neurodegeneration, anxiety, depression, and other stress-related disorders. Furthermore, the book provides an in-depth analysis of current therapeutic interventions, both pharmacological and behavioral, as well as natural antidotes that aim to mitigate the adverse effects of stress on the brain. By synthesizing evidence from cutting-edge research, this book offers valuable insights for scientists, clinicians, and mental health professionals seeking to understand and address the complex interplay between stress and brain health.

  • The Science of the Brain

    Function, Dysfunction and Disease
    • 1st Edition
    • Ari Rappoport
    • English
    The Science of the Brain: Function, Dysfunction and Disease delves into the intricate workings of the human brain, offering a groundbreaking examination of its complexities and the disorders that can arise when it malfunctions. This book, authored by a distinguished neuroscientist, unravels the mysteries of cognition, memory, and emotion while exploring how neurodegenerative diseases, mental health conditions, and brain injuries disrupt these processes. Designed to be accessible yet deeply informative, it bridges the gap between cutting-edge scientific research and real-world clinical applications, making it an invaluable resource for both professionals and curious readers.In addition to its comprehensive analysis of brain function, the book introduces readers to the latest innovations in neuroscience, including technological advancements in brain imaging and treatments. It also examines the ethical dilemmas posed by emerging technologies and their implications for society. With its blend of readability and scientific rigor, this work sheds light on the possibilities for future research and intervention, inspiring a deeper understanding of one of the most complex organs in the human body.

  • Imaging of Neurofluids, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 35-2
    • Nivedita Agarwal + 1 more
    • English
    In this issue of Neuroimaging Clinics, guest editors Drs. Nivedita Agarwal and Anja van der Kolk bring their considerable expertise to the topic of Imaging of Neurofluids. Top experts discuss key topics in this burgeoning field to create a primer ideal for neuroradiologists and radiologists. Topics include the basics of neurofluids, animal models, gadolinium-based imaging, perfusion-based imaging, diffusion tensor imaging, PET imaging, and specific articles on perivascular spaces, parasagittal dura mater and meningeal lymphatics, amyloid-related imaging abnormalities, and Alzheimer’s disease.

  • Essentials of Clinical Neurophysiology

    • 4th Edition
    • Karl E. Misulis + 1 more
    • English
    Up-to-date and easy to read, Essentials of Clinical Neurophysiology, Fourth Edition, details the basics of normal and abnormal neurologic function and provides authoritative clinical guidance on performing and interpreting today's full range of neurophysiologic studies. Drs. Karl E. Misulis and Thomas C. Head cover recent advances in technology as well as changes in training and practice patterns for EEG, EMG, EP, intraoperative monitoring, sleep studies, and autonomic testing. Offering a practical overview of this complex field, this one-stop resource is an excellent tool for board review and preparation.

  • Neuroglia in Neurologic and Psychiatric Disorders, Part II

    • 1st Edition
    • Volume 210
    • English
    Neuroglia in Neurologic and Psychiatric Disorders, Part II discusses glia relative to neurologic and psychiatric disorders, emphasizing cross-disease-glial cell dysfunctions. Driven by advances in genetics, transcriptomics, electrophysiologic and imaging techniques, as well as by the increase in knowledge on neuropathologic features and underlying disease mechanisms, this book bridges the gap between neuroglia basic science and neuroglia clinical research.

  • Early Detection of Alzheimer’s Disease

    Biological and Technological Advances
    • 1st Edition
    • Dennis Chan
    • English
    Early Detection of Alzheimer’s Disease: Biological and Technological Advances aims to introduce to a wide audience the high global priority problem of detecting AD prior to dementia onset. According to the Alzheimer’s Association, 5.8 million Americans are living with Alzheimer’s and care costs will cost the nation approximately $290 billion (2019 Alzheimer’s Disease Facts and Figures). With the failure of recent AD drug trials, many hypothesize that by the time symptoms appear, it is too late to be treated. Early detection can offer benefits such as more choice of medications, ability to participate in clinical trials, more time for family and for care planning. This book outlines potential solutions to the above problem using opportunities arising from the technology revolution, advances in neuroscience, and molecular biology. Most importantly, it discusses a paradigm shift from a reactive to a proactive diagnostic approach, aiming to detect disease before occurrence of symptoms. Topics covered include the use of sensing technologies (e.g. smartphones, smartwatches, Internet of Things) to detect early disease-related changes, the application of data science (machine learning/AI) to extract otherwise invisible disease features from these datasets and the potential to personalize diagnosis based on tracking changes in individual behaviours. Advances in blood-based biomarkers, brain imaging, and the potential for early diagnosis to aid interventions (lifestyle, dietary, pharmacological) to delay future development of dementia are also discussed.

  • Neuroglia in the Healthy Nervous System, Part I

    • 1st Edition
    • Volume 209
    • English
    Neuroglia in the Healthy Nervous System, Part I provides insights into newly emerging developments in neuroglia biology, focusing on the healthy nervous system. Driven by advances in genetics, transcriptomics, electrophysiological... and imaging techniques, this volume bridges the gap between neuroglia basic science and neuroglia clinical research. The book provides an overview of neuroglia biology, highlighting emerging technologies used to unravel the role of neuroglial cells in specific brain functions. The book also discusses strategies using neuroglia as a therapeutic target.

  • Differentiating Factors in Alzheimer’s Disease

    Gender, Ethnicity, Clinical and Treatment
    • 1st Edition
    • Henry M. Zeidan + 1 more
    • English
    Differentiating Factors in Alzheimer’s Disease: Gender, Ethnicity, Clinical and Treatment addresses the question why women differ from men in terms of their risk factors and how Alzheimer's disease can be prevented at the molecular level. This book reviews the epidemiology of Alzheimer's disease describing the differences in men's and women's brain anatomy and biochemistry that may account for why women are more likely to develop Alzheimer's disease. The authors offer actions that could help to prevent or slow the progression of Alzheimer's disease in addition to discussing the most recent pharmacological treatments.

  • Cerebral Asymmetries

    • 1st Edition
    • Volume 208
    • English
    Cerebral Asymmetries, Volume 208 summarizes research on cerebral hemispheric asymmetries and their implication for consciousness cognition, language emotion, behavior movement, and neurological disease. The book discusses anatomy and networks, genetics, hormones, and evolution, although it is primarily focused on animal research as it relates back to humans.

  • La maladie de Parkinson

    • 5th Edition
    • Luc Defebvre + 2 more
    • French
    La collection « Elsevier Monographies » permet aux praticiens d’approfondir et d’actualiser leurs connaissances, en exposant les données fondamentales actuelles et leurs applications dans la pratique clinique.La maladie de Parkinson est, après la maladie d’Alzheimer, l’affection neurologique la plus répandue au sein de la population après 50 ans. Sa prévalence augmentant avec l’âge, surtout au-delà de 60 ans, on peut prévoir dès aujourd’hui qu’avec le vieillissement de la population, le nombre de patients ne cessera d’augmenter dans les années à venir.Modèle d’affection neurodégénérative, la maladie de Parkinson se manifeste de façon variable selon les patients et les stades d’évolution, bien au-delà des seuls troubles moteurs qui la caractérisent. Ces dernières années, la recherche a connu des avancées significatives, tant sur le plan de la compréhension des mécanismes physiopathologiques et génétiques que sur celui des stratégies diagnostiques et thérapeutiques.Cette cinquième édition, réalisée en collaboration avec les meilleurs spécialistes cliniciens et chercheurs francophones, propose une actualisation complète des connaissances, enrichie de neuf nouveaux chapitres. Cette nouvelle édition aborde ainsi des thématiques essentielles comme l’histoire et l’épidémiologie de la maladie, les innovations en électrophysiologie, la santé bucco-dentaire, les indications des injections de toxine botulique ou encore le rôle du pharmacien d’officine. De plus, une attention particulière a été portée à la démarche neuropalliative, aux dispositifs de soins à domicile et aux questions pratiques telles que le permis de conduire.Ce livre s’adresse aux praticiens et à tous les professionnels de santé, médicaux et paramédicaux, exerçant dans un service de neurologie ou concernés par la pathologie parkinsonienne : neurologues, internes préparant le diplôme d’études spécialisées de neurologie, neuropsychologues, psychiatres, rééducateurs, orthophonistes et kinésithérapeutes.PO... CLÉSL’histoire et l’épidémiologie de la maladie.Les causes, la physiopathologie et les signes cliniques.La prise en charge thérapeutique des patients. Luc Defebvre est chef du service de neurologie et pathologie du mouvement, responsable du Centre Expert Parkinson, unité Inserm 1172, CHU et université de Lille.Marc Vérin est neurologue au service de neurologie, CHU d’Orléans, laboratoire interdisciplinaire pour l’innovation et la recherche en santé d’Orléans (LI2RSO), équipe « Brain Clinical and Experimental Neuroplasticity » (B-CLINE), université d’Orléans.

  • Coma, Stupor, and Related Disorders of Consciousness

    • 1st Edition
    • Volume 207
    • Peter W. Kaplan + 1 more
    • English
    Coma, Stupor, and Related Disorders of Consciousness reviews recent research and best practice in the assessment and treatment of coma, stupor, and disorders of consciousness. It encompasses the neural circuits, anatomy & physiology of stupor and coma, differential diagnosis and clinical assessment, imagery, EEGs, therapy/intervention... decision making and prognosis.

  • The Auditory Cerebellum

    Function and Dysfunction
    • 1st Edition
    • Jos J. Eggermont
    • English
    The Auditory Cerebellum: Function and Dysfunction focuses on the sensory and cognitive aspects of the cerebellum, with an emphasis on hearing, speech, music, speaking, and singing. This book fills the gap for information needed in audiology and auditory neuroscience, tinnitus, and developmental disorders with a strong auditory component. This book starts with a general overview on the connectivity between the cerebellum and auditory subcortical and cortical areas, including general cortical networks. There are several chapters devoted to the timing aspects of the cerebellum underlying speech and music perception as well as motor aspects in speaking and singing.Also discussed is the role of the cerebellum in hearing impairment, tinnitus, developmental disorders with a strong auditory component, including dyslexia, autism, attention deficit, and hyperactivity disorder. Dr. Jos Eggermont, a leading researcher in the field, uses a systems analysis approach that covers electrophysiology and neural imaging, both in animals and humans.

  • Circadian Rhythms, Sleep, and Sleep Disorders

    • 1st Edition
    • Volume 206
    • English
    Circadian rhythms, sleep, and sleep disorders covers the topic in two sections focusing on basic science and clinical application. In the basic section, new developments and research findings focusing on basic circadian rhythm and sleep physiology in animals and humans is highlighted. The chapters are written in short mini-review formats in order to concisely describe the fundamentals, and current hot topics.The basic part starts with a chapter on the fundamentals and new discoveries on oscillating circuitries in the sleeping rodent and human brain. This sets the stage for chap 2, focusing on circadian and homeostatic aspects of human sleep regulation. Chap 3 extends these aspects to human cognition. The next chapter reports on visual and non-visual effects of light on human behavior, particularly endocrine and electrophysiological correlates. Chap 5 covers chronic sleep restriction effects on functional connectivity states. The last two chapters (6 and 7) give a broad overview on sleep modeling across physiological levels, with a focus on a quantitative model of sleep-wake dynamics based on the physiology of the brainstem ascending arousal system.The clinical section of the book describes the circadian rhythm sleep-wake disorders, from epidemiology to clinical picture and treatment. Disorders covered include delayed and advanced sleep phase syndrome, Irregular sleep-wake rhythm disorder, shift work disorder, restless legs syndrome, nocturnal eating syndrome, narcolepsy, and sleep apnea. Pharmacological and non-pharmacological treatments of insomnia are explored, as well as the role of sleep-wake modulation in the pathogenesis and clinical profile of neurodegenerative disorders, such as Parkinson’s disease and Alzheimer’s disease.

  • Neurobiology of Infectious Diseases

    • 1st Edition
    • Volume 1
    • Tatiana Barichello + 2 more
    • English
    Neurobiology of Infectious Diseases covers mechanisms underlying infectious diseases. It is divided into six distinct sections, beginning with the foundations of Neuroinfection. This section includes chapters on the role microbiota-gut-brain axis and specialized blood-neuronal barriers play in neurobiology of infectious diseases. The next three sections detail various bacterial infections, parasitic infections, viral infections, and fungal infections of the central nervous system. The last section reviews the proteins and other peripheral mediators that affect the central nervous system. Internationally contributed by experts in the field this book sets the foundation of neurobiology and infectious disease.Neurobiology is the study of cells of the nervous system and the organization of these cells into functional circuits that process information and mediate behavior. Current research is vital for determining pharmaceutical and medicinal treatments for neurological disorders, psychiatric disorders and diseases.

  • Handbook of Imaging in Multiple Sclerosis

    • 1st Edition
    • Dejan Jakimovski + 1 more
    • English
    Handbook of Imaging in Multiple Sclerosis provides an up-to-date introduction into multiple sclerosis disease, including new findings on the pathophysiological processes, the clinical presentation, diagnosis, and treatment of the disease. This book includes in-depth chapters exploring the use of conventional and non-conventional imaging methods. These chapters cover magnetic resonance imaging (MRI) specific topics such as measurement of brain atrophy and susceptibility-weigh... imaging. Additional chapters explore the use of additional imaging methods such as positron emission tomography (PET), optical coherence tomography (OCT) and high field MRI (use of 7T MRI scanners).

  • Capute and Accardo's Neurodevelopmental Disabilities in Infancy and Childhood

    • 4th Edition
    • Fatima Y Ismail + 2 more
    • English
    **Selected for 2026 Doody's Core Titles in Neurology**Capute and Accardo’s Neurodevelopmental Disabilities in Infancy and Childhood, Fourth Edition provides updated foundational, theoretical, and practical knowledge on the spectrum and continuum of neurodevelopmental disabilities shaped by ongoing advances in neuroscience and related disciplines. It reviews the over-arching principles of assessment, diagnosis, and management of patients with a wide range of neurodevelopmental disabilities. Streamlined or fully rewritten chapters, including developmental screening and surveillance, neuroimaging and genetic evaluation, early intervention, principles of pharmacological treatment, principles of successful management programs, aging and transition planning, telemedicine and care in low-resource settings are included.The book's practical, expert-led approach aims to prepare future clinicians to skillfully assess and manage children with neurodevelopmental disabilities with the aid of clinical approach flowcharts to common presentations, diagnostic algorithms and clinic notes templates.

  • Translational Models of Parkinson’s Disease and related Movement Disorders

    • 1st Edition
    • Wael Mohamed
    • English
    Translational Models of Parkinson’s Disease and Related Movement Disorders focuses on cutting-edge techniques for creating and validating current Parkinson’s Disease translational experimental models. Various characteristics of these models are examined, including the prion-like properties of -synuclein, mitochondrial functions connected to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway connected to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells). This book also highlights the future possibilities of introducing new models for Parkinson’s Disease and related movements disorders, underscoring current advancements, pre-clinical and clinical developments, and future scope related to numerous models.

  • Essential Guide to Neurodegenerative Disorders

    Mechanistic, Diagnostic and Therapeutic Advances
    • 1st Edition
    • Wael Mohamed
    • English
    Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration. Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington's disease, Parkinson's disease, Friedreich' s ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches.

  • Neuropathic Pain

    • 1st Edition
    • Volume 179
    • English
    Neuropathic Pain, Volume 179 of the latest release in the International Review of Neurobiology serial,, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • The Neurodegeneration Revolution

    Emerging Therapies and Sustainable Solutions
    • 1st Edition
    • Trideva Sastri Koduru + 3 more
    • English
    The Neurodegeneration Revolution: Emerging Therapies and Sustainable Solutions provides insights into the mechanics, characteristics, behavior, application, and manufacturing of advanced materials such as nanowires, 2D materials, biomaterials, smart materials, and more. The first section discusses the mechanics and electronic and magnetic properties of nanomaterials, photonic, and photonic materials and devices, 2D magnetic materials, smart materials and coatings, metamaterials, and microdevices and sensors. The second section of the book covers manufacturing technologies and methods of previously discussed materials, outlining manufacturing techniques for additive manufacturing of metallic lattice structures, biomedical alloys, shape memory alloys, multifunctional polymer composites, nanocomposite structures, ceramics, and batteries.

  • Neurocritical Care, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 43-1
    • Alejandro A. Rabinstein
    • English
    In this issue of Neurologic Clinics, guest editor Dr. Alejandro A. Rabinstein brings his considerable expertise to the topic of Neurocritical Care. Top experts cover key topics in the field, including ICU delirium: a neurological perspective; prolonged monitoring of brain electrical activity in the ICU; AI applications in neurocritical care; brain injury after cardiac arrest: refining prognosis; advances in the critical care of ischemic brain infarction; and many more.

  • Vagus Nerve Stimulation

    • 1st Edition
    • Peter Staats + 3 more
    • English
    In the complex realm of our physiology, the vagus nerve stands as a silent orchestrator, influencing health and disease in ways that have long been underestimated. Vagus Nerve Stimulation delves into the profound significance of this 10th cranial nerve, tracing its course through the body and illuminating its role as a vital component of the parasympathetic nervous system.This comprehensive reference, contributed by leading experts at the forefront of medical science, unveils the groundbreaking field of vagus nerve stimulation—a non-invasive approach to harness the body's innate potential for health optimization, inflammation control, and disease modification. Contributed by leading experts in the field, this comprehensive volume serves as a compendium of current knowledge about stimulating the vagus nerve in many different disease states. This book starts with the foundational insights in Basic Science and Technical Considerations. From there, it continues to Neurologic Conditions, where chapters explore applications for epilepsy, cluster headaches, and concussions. Evolving Therapy for Neurologic Conditions introduces cutting-edge treatments for acute ischemic stroke, synaptic plasticity, and neurodegenerative disorders. The book extends into Psychiatric and Somatic Conditions, providing insights into anxiety, depression, addiction disorders, and more. Conventional Inflammatory Conditions shed light on vagus nerve stimulation's role in combatting sepsis, immune-mediated inflammatory diseases, and metabolic syndrome, among others. Concluding with a foray into Oncology, the book highlights the potential of vagus nerve stimulation in addressing the lingering effects of long covid and migraine. With an authoritative blend of scientific rigor and practical application, this reference serves as an indispensable guide to the vast landscape of vagus nerve stimulation, transforming our understanding of health and wellness.

  • Osteomyelitis and Discitis of the Spine

    A Guide for the Management of Infectious Etiology of the Vertebral Column and Neurological Components
    • 1st Edition
    • Dia R Halalmeh + 1 more
    • English
    Osteomyelitis and Discitis of the Spine: A Guide for the Management of Infectious Etiology of the Vertebral Column and Neurological Components examines these spinal conditions and provides readers with the most appropriate management plans, including surgical treatment together with its indications. This book guides spine neurosurgeons and others when choosing the optimal surgical approach for their patients, shedding light on current advances in surgical techniques used in the management of vertebral osteomyelitis and discitis, particularly minimally invasive spine approaches.With authors representing diverse specialties, chapters reflect current clinical and surgical practice and discuss pathophysiology and pain management and rehabilitation. The book begins with related anatomy and extends to post-management rehabilitation and pain control, including a chapter dedicated to pediatric patients and their differing causative organisms, etiology, diagnostic modalities, and pathophysiology. This reference will provide increased awareness of potential spinal infection, facilitating multidisciplinary management plans, improving patient safety and outcomes, and enabling early intervention alternatives that improve patient outcomes and long-term quality of life.

  • The Subarachnoid Space: Percutaneous Access for Diagnosis and Image-Guided therapies, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 35-1
    • Bryan Lanzman + 1 more
    • English
    In this issue of Neuroimaging Clinics, guest editors Drs. Bryan Lanzman and Tarik F. Massoud bring their considerable expertise to the topic of The Subarachnoid Space: Percutaneous Access for Diagnosis and Image-Guided Therapies. In this first-of-its-kind issue, top experts the field discuss a wide range of topics related to the subarachnoid space, including imaging anatomy, guided lumbar punctures, puncture complications, myelography, cisternography, and much more.

  • Advances in Alcohol Use Disorder Treatment

    • 1st Edition
    • Volume 178
    • English
    Advances in Alcohol Use Disorder Treatment, Volume 178 in the International Review in Neurobiology series, presents a comprehensive exploration of emerging therapies and approaches in the field. Topics in this new release include Introduction: Current Treatments, Oxytocin and Vasopressin, Neuroactive steroids, Pharmacological activators of ALDH2, Anti inflammatories and mesenchymal stem cells, Sodium oxybate, Psychedelic compounds, Cannabinoids, Environmental Enrichment, Animal models and translational challenges, GABAergic compounds, and Ghrelin system and GLP-1.

  • Pediatric Epilepsy Surgery Techniques

    Controversies and Evidence
    • 1st Edition
    • Aria Fallah + 2 more
    • English
    Pediatric Epilepsy Surgery Techniques: Controversies and Evidence offers clinicians a roadmap for navigating the complex decision-making process involved in selecting surgical interventions for children with drug-resistant epilepsy. Over the last decade, the landscape of pediatric epilepsy surgery has undergone substantial transformation, marked by the introduction of several emerging technologies that are now supported by an expanding body of evidence, yet leading to a wide range of treatment practices. This book addresses several decision-making dichotomies in pediatric epilepsy surgery, both in terms of established and novel surgical modalities and techniques. The book explores long-standing debated topics, such as the relative benefits of disconnective compared to resective strategies, the utility of surgical adjuncts like intra-operative electrocorticography... as well as rationales for different surgical approaches, namely selective amygdalo-hippocampec... versus anteromesial temporal lobectomy. Further, it addresses dichotomies between traditional approaches and contemporary modalities, such as microsurgical resection versus laser interstitial thermal therapy. Chapters also offer comparisons of modern technologies, such as different neuromodulation strategies, including vagus nerve stimulation, deep brain stimulation, and responsive neurostimulation.Thi... book provides readers with the relevant scientific literature and expert commentary to inform evidence-based approaches to surgical care in pediatric drug-resistant epilepsy.

  • Pediatric Neurovascular Disorders, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 34-4
    • Prakash Muthusami + 1 more
    • English
    In this issue of Neuroimaging Clinics, guest editors Drs. Prakash Muthusami and Todd Abruzzo bring their considerable expertise to the topic of Pediatric Neurovascular Disorders. Top experts in the field discuss catheter-directed cerebral and spinal angiography in children; fetal neurovascular malformations; intracranial arterial aneurysms in childhood; neurovascular trauma in children; spinal vascular malformations of childhood; and more.

  • The Immune System

    Mental Health and Neurological Conditions
    • 2nd Edition
    • Hymie Anisman + 2 more
    • English
    The Immune System: Mental Health and Neurological Conditions fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. This book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. New chapters and sections on peripheral and central mechanisms in relation to viral pathogens, RNA editing to treat diseases, and COVID-19 will be included. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. This book covers both mental-health conditions and degenerative disorders of the brain, including depression, schizophrenia, autism-like spectrum disorders, Parkinson’s and Alzheimer’s-like dementia.

  • Genome Editing for Neurodegenerative Diseases

    From Concept to Clinical Trials
    • 1st Edition
    • Sandeep Kumar Singh + 3 more
    • English
    Genome Editing for Neurodegenerative Diseases: From Concept to Clinical Trials examines recent advances in neurodegenerative disease research and clinical challenges in practical applications. With an emphasis on genome editing tools such as ZFNs, TALENSs and CRISPR-Cas, this book sheds light on the possibilities to counteract genetic and neurodegenerative diseases. It will be of interest to researchers in neuroscience and biopharmaceuticals, as well as clinicians specializing in neurodegenerative diseases.

  • Radiomics and Radiogenomics in Neuro-Oncology

    An Artificial Intelligence Paradigm – Volume 2: Genetics and Clinical Applications
    • 1st Edition
    • Sanjay Saxena + 1 more
    • English
    Radiomics and Radiogenomics in Neuro-Oncology: An Artificial Intelligence Paradigm—Volume 2: Genetics and Clinical Applications provides readers with a broad and detailed framework for radiomics and radiogenomics (R-n-R) approaches with AI in neuro-oncology. It delves into the study of cancer biology and genomics, presenting methods and techniques for analyzing these elements. The book also highlights current solutions that R-n-R can offer for personalized patient treatments, as well as discusses the limitations and future prospects of AI technologies.Volume 1: Radiogenomics Flow Using Artificial Intelligence covers the genomics and molecular study of brain cancer, medical imaging modalities and their analysis in neuro-oncology, and the development of prognostic and predictive models using radiomics.Volume 2: Genetics and Clinical Applications extends the discussion to imaging signatures that correlate with molecular characteristics of brain cancer, clinical applications of R-n-R in neuro-oncology, and the use of Machine Learning and Deep Learning approaches for R-n-R in neuro-oncology.

  • Targeted Therapy for the Central Nervous System

    Formulation, Clinical Challenges, and Regulatory Strategies
    • 1st Edition
    • Viral Patel + 3 more
    • English
    Targeted Therapy for the Central Nervous System: Formulation, Clinical Challenges, and Regulatory Strategies presents research on various delivery methods of drugs to the central nervous system and brain. This volume examines targeted therapies for neurodegenerative disorders and succinctly outlines the future of drug delivery systems, highlighting significant advancements specifically relating to central nervous system delivery. This book will be of great interest to researchers working in the field of neuroscience and pharmacology as well as clinicians (pharmacists, radiologists, psychiatrists).

  • The Fundamentals of Stereoelectroencephalography

    • 1st Edition
    • Patrick Chauvel + 3 more
    • English
    Gain confidence and expertise with stereoelectroencepha... (SEEG) as a presurgical method for epilepsy with this helpful resource. Edited and written by leading experts in the field, Stereoelectroencepha... teaches the scientific and medical bases of SEEG through its essential disciplines (anatomy, biophysics, electrophysiology, and cognitive and behavioral neuroscience) and their interrelations. It fully covers the basic and clinical aspects of the pharmaco-resistant epilepsies investigated with SEEG and their surgical indications.

  • Cell and Gene Therapies for Neurologic Diseases

    • 1st Edition
    • Volume 205
    • English
    Cell and Gene Therapies for Neurologic Diseases, Volume 205 comprehensively covers the scientific background, translational efforts, clinical developments and registered biologics that have entered into clinical practice. Coverage includes types of therapies available and in development, and best practice uses for a variety of neurological disorders including Parkinson’s, Huntington’s, ALS, stroke, spinal cord RP, demyelination, and epilepsy. As the emergence of gene and cellular therapeutics has changed the clinical landscape for a variety of disorders, and is now ready to do so for neurological diseases, these therapeutic modalities currently complement, and may in time, supplant small molecule drugs.

  • Neuropsychology for Neurologists, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 42-4
    • Jane Paulsen + 1 more
    • English
    In this issue of Neurologic Clinics, guest editors Drs. Jane S. Paulsen and Carissa Gehl bring their considerable expertise to the topic of Neuropsychology for Neurologists. Top experts provide an overview of neuropsychological assessment that extends beyond mental status examination to facilitate diagnostic considerations, clinical decision making with regarding to critical life skills, and suggestions for rehabilitation. This issue also includes characterization of typical neuropsychological features associated with specific illnesses/injuries and consideration of behavioral signs and symptoms, functional capacity, and quality of life for individuals with these diagnoses.

  • Brain and Organ Communication

    Effects of Crosstalk on Neurophysiology
    • 1st Edition
    • Charu Mahajan + 2 more
    • English
    Brain and Organ Communication: Effects of Crosstalk on Neurophysiology examines the intricate relationship between the brain and other organ systems within the body. With an emphasis on homeostasis of these systems, this book also explores how various systems are related and affected by the brain injury or organ damage from a neurophysiological standpoint.This book will be most useful to researchers in neuroscience and graduate students studying neurophysiology. Those with an interest in endocrinology and clinicians in various branches of neuroscience and physiology will also find this book of interest.

  • Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease, Seventh Edition

    Volume 2
    • 7th Edition
    • Volume 2
    • Roger N. Rosenberg + 1 more
    • English
    Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Seventh Edition provides a comprehensive introduction and reference to the foundations and practical aspects relevant to the majority of neurologic and psychiatric disease. This updated volume focuses on degenerative disorders, movement disorders, neuro-oncology, neurocutaneous disorders, epilepsy, white matter diseases, neuropathies and neuronopathies, muscle and neuromuscular junction disorders, stroke, psychiatric disease, and a neurologic gene map. This volume includes new chapters on Von Hippel-Lindau disease, antisocial and violent behavior and Autism. A favorite of over four generations of students, clinicians and scholars, this new edition retains and expands on the informative, concise and critical tone of the previous edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, related professionals, and for the neuroscience and neurology research community at large.

  • Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease, Seventh Edition

    Volume 1
    • 7th Edition
    • Volume 1
    • Roger N. Rosenberg + 1 more
    • English
    Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Seventh Edition, provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to neurologic and psychiatric disease. This volume has been thoroughly revised and includes newly commissioned chapters on ethics, genetic counselling and genet therapy for the central nervous system disorders. A favorite of over four generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the previous edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community at large.

  • Stem Cells in Neurotoxicology

    • 1st Edition
    • Volume 12
    • English
    Stem Cells in Neurotoxicology, Volume Twelve in the Advances in Neurotoxicology series, presents interesting chapters written by an international board of authors. Chapters in this new release include Brain organoids as a translational model of human developmental neurotoxicity, Self-organizing human neuronal cultures in the modeling of environmental impacts on learning and intelligence, Utilization of human stem cell/neural progenitor tests to examine neurotoxic impacts on differentiation, Characterization of neuronal and other cellular sub-types in human stem cell cortical neuron differentiations, Utility of human stem cell models to study persistent neurotoxicity, and Utility of human stem cell models to study chronic neurotoxicity.

  • Medical Image and Signal Analysis in Brain Research

    • 1st Edition
    • Volume 290
    • English
    Progress in Brain Research, Volume 290 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this release include Image Analysis for Spinocerebellar Ataxia Type 3, Brain structural network modular and connectivity alterations in subtype of patients with migraine, Brain Functional Networks and Structures that Categorize Type 2 Bipolar Disorder and Major Depression, Reinforcement Learning Classification in fNIRS Signal of Olfactory Stimulated, The method of brain-computer interface using the forehead instead of the visual area to receive SSVEP signals and signal processing, and more.Additional chapters cover The relationship between flash-induced SSVEP in DELTA frequency band and sleep, Enhancing Facial Feature De-Identification in Multi-Frame Brain Images: A Generative Adversarial Network Approach, Comparative Analysis of MRI Markers in Heat and Mechanical Pain Sensitivity, and Analysis of the Difference Between Alzheimer’s Disease, Mild Cognitive Impairment and Normal People by Using Fractal Dimensions and Small-World Network.

  • Neuroscience Research in Short-Duration Human Spaceflight

    • 1st Edition
    • Bader Shirah
    • English
    Neuroscience Research in Short-duration Human Spaceflight encapsulates a groundbreaking neuroscience portfolio conducted during the Axiom Mission 2 in May 2023, offering an examination of the effects of short-duration orbital spaceflight on aspects of the human brain. Addressing limitations in existing literature, the research includes astronauts of diverse ages, genders, and ethnic backgrounds, broadening the understanding of the impact of spaceflight on human physiology. A significant aspect of the suite of studies is the validation of two novel devices providing unprecedented information about the pupillary light reflex and neuroimaging in microgravity: automated pupillometry and functional near-infrared spectroscopy. The portfolio extends to explore spaceflight-associat... neuro-ocular syndrome, offering valuable contributions to the evolving field of space medicine. Furthermore, the research delves into the utilization of electroencephalograp... to monitor brain activity, acknowledging its potential in assessing cognitive health, stress levels, and mental workload in real time. Despite promising prospects, challenges in electroencephalograp... system adaptability within the International Space Station environment are highlighted, emphasizing the need for specialized design considerations. In addition, analysis is extended into the molecular biomarkers through minimally invasive blood monitoring. This book represents a pivotal advancement in space neuroscience, laying the foundation for safer space travel and fostering the development of monitoring tools crucial to observing adverse changes and potentially developing countermeasures that can aid in the establishment of a permanent human presence beyond Earth.

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