Learning and Memory: A Comprehensive Reference, Third Edition, Four Volume Set is the authoritative resource for scientists and students interested in all facets of learning and memory. This updated edition will include chapters that reflect the rapidly evolving, state-of-the-art of research in this area, from the molecular mechanisms of consolidation and forgetting to the cognitive mechanisms of eyewitness memory. No other reference work comes close to providing such breadth covered in so much depth and thus is a valuable tool for all academics and researchers in the field of neuroscience, psychology, psychiatry, neurobiology and neurology.
Developmental Dyscalculia: From Brain Mechanisms to Educational Applications presents research with a domain-general approach. It examines issues in the fields of numerical and non-numerical cognitive domains, neuro- mechanisms, and pedagogic issues to pave the way to a bridge between lab research, daily life, and curriculum applications, with a goal of finding a pathway to early diagnosis and interventions of developmental dyscalculia. It will be of interest to researchers with interests in cognitive neuroscience and education, to contribute fruitful discussions between education and neuro-cognition. 
The Handbook of Dopamine explores the function of dopamine neurons that spans from molecular, cellular, synaptic, and circuits to behavior, and finally, dysfunction in disease. This volume maps out the anatomical organization and molecular diversity of dopamine that is increasingly better understood through large scale analyses. It compiles the latest research from many prominent figures still involved in dopamine research with content included that reflects many new developments, such as genetic analyses, manipulations, optogenetics, fluorescent probes, real-time optical imaging, multichannel recordings, behavioral analyses, and human neuron modeling.
Blindness, Volume 292 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Temperature as a circadian timing cue in the visually impaired, Visual experience affects neural correlates of audio-haptic integration: A case study of non-sighted individuals, Visual experience affects neural correlates of audio-haptic integration: A case study of non-sighted individuals, Measuring residual visual function after cerebral damage – a potential path for optimizing rehabilitation approaches, and Persistence of training-induced visual improvements after occipital stroke, amongst other topics.Other chapters in this release include Well-being, mental health, and sleep in children and young people with vision impairment: A narrative review, Changes to the brain due to visual impairment, Information Processing in People with Visual Impairments, Case studies of the migraine aura in the blind or partially sighted, HABEMO: an innovative haptic tool for investigating the bodily representation of mental states in individuals with visual impairments, and Affect in the dark: navigating the complex landscape of social cognition in blindness, and An overview of quality of life and visual outcomes in AMD.
Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies is a comprehensive exploration of how stress affects the brain at a molecular level and its broader implications for mental and neurological health. The book delves into the mechanisms by which stress triggers changes in brain function, including the activation of the hypothalamic-pituitary-adrenal (HPA) axis, synaptic plasticity alterations, oxidative stress, neuroinflammation, and mitochondrial dysfunction. It examines how these molecular processes contribute to conditions such as neurodegeneration, anxiety, depression, and other stress-related disorders. Furthermore, the book provides an in-depth analysis of current therapeutic interventions, both pharmacological and behavioral, as well as natural antidotes that aim to mitigate the adverse effects of stress on the brain. By synthesizing evidence from cutting-edge research, this book offers valuable insights for scientists, clinicians, and mental health professionals seeking to understand and address the complex interplay between stress and brain health.
Early Detection of Alzheimer’s Disease: Biological and Technological Advances aims to introduce to a wide audience the high global priority problem of detecting AD prior to dementia onset. According to the Alzheimer’s Association, 5.8 million Americans are living with Alzheimer’s and care costs will cost the nation approximately $290 billion (2019 Alzheimer’s Disease Facts and Figures). With the failure of recent AD drug trials, many hypothesize that by the time symptoms appear, it is too late to be treated. Early detection can offer benefits such as more choice of medications, ability to participate in clinical trials, more time for family and for care planning. This book outlines potential solutions to the above problem using opportunities arising from the technology revolution, advances in neuroscience, and molecular biology. Most importantly, it discusses a paradigm shift from a reactive to a proactive diagnostic approach, aiming to detect disease before occurrence of symptoms. Topics covered include the use of sensing technologies (e.g. smartphones, smartwatches, Internet of Things) to detect early disease-related changes, the application of data science (machine learning/AI) to extract otherwise invisible disease features from these datasets and the potential to personalize diagnosis based on tracking changes in individual behaviours. Advances in blood-based biomarkers, brain imaging, and the potential for early diagnosis to aid interventions (lifestyle, dietary, pharmacological) to delay future development of dementia are also discussed.
Handbook of Imaging in Multiple Sclerosis provides an up-to-date introduction into multiple sclerosis disease, including new findings on the pathophysiological processes, the clinical presentation, diagnosis, and treatment of the disease. This book includes in-depth chapters exploring the use of conventional and non-conventional imaging methods. These chapters cover magnetic resonance imaging (MRI) specific topics such as measurement of brain atrophy and susceptibility-weighted imaging. Additional chapters explore the use of additional imaging methods such as positron emission tomography (PET), optical coherence tomography (OCT) and high field MRI (use of 7T MRI scanners).
Capute and Accardo’s Neurodevelopmental Disabilities in Infancy and Childhood, Fourth Edition provides updated foundational, theoretical, and practical knowledge on the spectrum and continuum of neurodevelopmental disabilities shaped by ongoing advances in neuroscience and related disciplines. It reviews the over-arching principles of assessment, diagnosis, and management of patients with a wide range of neurodevelopmental disabilities. Streamlined or fully rewritten chapters, including developmental screening and surveillance, neuroimaging and genetic evaluation, early intervention, principles of pharmacological treatment, principles of successful management programs, aging and transition planning, telemedicine and care in low-resource settings are included.The book's practical, expert-led approach aims to prepare future clinicians to skillfully assess and manage children with neurodevelopmental disabilities with the aid of clinical approach flowcharts to common presentations, diagnostic algorithms and clinic notes templates.
Translational Models of Parkinson’s Disease and Related Movement Disorders focuses on cutting-edge techniques for creating and validating current Parkinson’s Disease translational experimental models. Various characteristics of these models are examined, including the prion-like properties of -synuclein, mitochondrial functions connected to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway connected to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells). This book also highlights the future possibilities of introducing new models for Parkinson’s Disease and related movements disorders, underscoring current advancements, pre-clinical and clinical developments, and future scope related to numerous models.
Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration. Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington's disease, Parkinson's disease, Friedreich' s ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches.