Books in Neurotoxicology

Therapies for Treatment-Resistant Depression

1st Edition
August 1, 2025
James Murrough + 1 more
English
Paperback
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eBook
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Therapies for Treatment-Resistant Depression: Neuropharmacology and Neurostimulation provides readers with an authoritative, comprehensive and targeted treatment guide. The first section reviews the essential knowledge and methods of clinical neuroscience and neuropsychopharmacol... techniques as they apply to novel treatment discovery for depression. This is followed by detailed chapters on ketamine, esketamine, other glutamate modulators in development, GABA modulators, neuropeptides, anti-inflammatory agents, and other classes of novel therapeutics under study for TRD and related mood disorders.The last section consists of a set of chapters of special interest that includes current and future research directions, development of psilocybin-based interventions and other psychedelic compounds currently under study for TRD and advances in biomarker-guided and personalized treatment. Edited by world renowned experts in the field, this book is the ultimate resource for researchers and clinicians.

Neurotoxicity of Solvents

1st Edition
Volume 14
July 1, 2025
Christoph van Thriel
English
Hardback
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eBook
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Neurotoxicity of Solvents, Volume Fourteen highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including the Effect of toluene on memory: A focus on humans, experimental models and treatment approaches, Neurotoxicological Mechanisms of Ethanol, Neurobehavioral Aspects and Methodology of Solvents, Organic solvents and neurodegenerative diseases: exploring a possible link, Neurotoxicity of propylene ethers, An ecotoxicological view on solvents neurotoxicity, and The olfactory system as a target of solvent toxicity.

Mitochondria and Neurotoxicity

1st Edition
Volume 13
June 1, 2025
Lucio G. Costa + 2 more
English
Hardback
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eBook
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Mitochondria and Neurotoxicity, Volume Thirteen in the Advances in Neurotoxicology series, presents interesting chapters written by an international board of authors. Chapters in this new release include Introduction to mitochondrial toxicity: form, function, and signaling, Respirometry parameters as indicators of neurotoxicity, Pesticide exposure and hippocampal neurogenesis: Role of ER stress and mitochondria, Gene Therapy Approaches to Abrogate Pathogenic Mechanisms in Parkinson’s disease, Mitochondrial dysfunction induced by trichloroethylene in Parkinson’s disease, and Gut-brain axis inflammation induced by mitochondrial toxicants.

Stem Cells in Neurotoxicology

1st Edition
Volume 12
September 25, 2024
Lucio G. Costa + 2 more
English
Hardback
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eBook
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Stem Cells in Neurotoxicology, Volume Twelve in the Advances in Neurotoxicology series, presents interesting chapters written by an international board of authors. Chapters in this new release include Brain organoids as a translational model of human developmental neurotoxicity, Self-organizing human neuronal cultures in the modeling of environmental impacts on learning and intelligence, Utilization of human stem cell/neural progenitor tests to examine neurotoxic impacts on differentiation, Characterization of neuronal and other cellular sub-types in human stem cell cortical neuron differentiations, Utility of human stem cell models to study persistent neurotoxicity, and Utility of human stem cell models to study chronic neurotoxicity.

The Microbiome and Neurotoxicity

1st Edition
Volume 11
April 30, 2024
Michael Aschner + 2 more
English
Hardback
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eBook
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Advances in Neurotoxicology, Volume 11 presents interesting chapters written by an international board of authors. Chapters in this new release include Gut microbiota as a mediator on the neurotoxicity of mercury, Relationships between lead-induced learning and memory impairments and gut microbiota disturbance in mice, Utility of zebrafish-based models in understanding molecular mechanisms of neurotoxicity mediated by the gut-brain axis, Alterations of gut microbiota linking environmental exposures to neurotoxicity, Iron Toxicity, Ferroptosis and Microbiota in Parkinson’s Disease: Implications for Novel Targets, and Modulation of gut microbiota with probiotics as a strategy to counteract endogenous and exogenous neurotoxicity.

Neurotoxicity of Halogenated Organic Compounds

1st Edition
Volume 10
October 25, 2023
Lucio G. Costa + 2 more
English
Hardback
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eBook
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Neurotoxicity of Halogenated Organic Compounds, Volume 10 covers three groups of Halogenated Organic Compounds (Chlorinated, Brominated, and Fluorinated Compounds) that are legacy and emerging contaminants, providing background information, characteristics, physicochemical properties, environmental contamination, and human exposure. Specific chapters covered in this release include Perspective on Halogenated Organic Compounds, The Neurotoxicity of Polychlorinated Biphenyls (PCBs), Neuroendocrine Effects of Polychlorinated Biphenyls (PCBs), Mechanisms of PCB Neurotoxicity: AHR and THR Dogma meet RYR reality, Microbiome and the Neurotoxicity of Brominated Flame Retardants (BFRs), and much more. Other chapters cover Neuroendocrine Effects of Brominated Flame Retardants (BFRs), Focused on Polybrominated Diphenyl Ethers (PBDEs), Neurochemical Effects of Halogenated Organic Compounds: Possible Mode(s) of action and Structure-Activity Relationships, The Neurotoxic Effects of Perfluoroalkyl Substances (PFAS) in Animal Models and Human Cohorts, Neurochemical Mechanisms of Perfluoroalkyl Substances (PFAS) Neurotoxic Action, and Future Directions and Regulatory aspects of Halogenated Organic Compounds.

Alternative Methods in Neurotoxicology

1st Edition
Volume 9
May 25, 2023
Joao Batista Rocha + 2 more
English
Hardback
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eBook
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Alternative Methods in Neurotoxicology, Volume Nine, the latest release in this series, provides an overview of important in vitro and non-vertebrate animal models available to study the neurotoxicity of a range of toxicants of occupational and environmental relevance. Chapters in this new release include Evaluation of mitochondrial function in neurotoxicology using alternative models, Planarians as a model to study neurotoxic agents, Role of Drosophila melanogaster in neurotoxicology studies: Responses to different harmful substances, Neurotoxicology of metals and metallic nanoparticles in Caenorhabditis elegans, Neurotoxicology of environmental toxicants using Caenorhabditis elegans as a model, Nauphoeta cinerea as an emerging model in neurotoxicology, and more. Other chapters cover Human Neural Stem Cells in Developmental Neurotoxicology: Current Scenario and Future Prospects, Use of Drosophila melanogaster for advances in developmental neurotoxicology studies, 3D neurospheres and neurotoxicity of organophosphorus and TCE, Genetic factors in methylmercury-induce... neurotoxicity: what we have learned from Caenorhabditis elegans models, and more.

Neurotoxicity of Drugs of Abuse

1st Edition
Volume 8
September 15, 2022
Lucio G. Costa + 2 more
English
Hardback
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eBook
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Neurotoxicity of Drugs of Abuse, Volume Eight provides carefully crafted reviews on the disruptive impact of drugs of abuse on the central nervous system. The neurotoxicity potential of several agents including marijuana, fentanyl, and ketamine are carefully reviewed, and their short-term and chronic effects are categorized. Pharmacokinetic profiles as well as mechanisms of action for these and other drugs of abuse such as alcohol and nicotine are also evaluated. The implications of short and long-term abuse for agents such as PCP are also characterized. The reader will come away with a fuller understanding of the adverse effects of drugs of abuse on the nervous system.

Occupational Neurotoxicology

1st Edition
Volume 7
July 15, 2022
Michael Aschner + 2 more
English
Hardback
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eBook
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Occupational Neurotoxicology, Volume Seven covers neurotoxicants and exposures to a variety of hazards in the workplace and how they can affect nervous functions in different ways. Metals and organic compounds, both at high level acute exposure and long-term low-level exposure can affect motor functions, cognition, behavior and neurosensory functions. Sections cover Oil leakage in aircraft, aerotoxic syndrome, Organic solvents, WTC neurotoxicities, Environmental intolerance, Pesticides, Carbon monoxide, Mercury Neurotoxicity in Gold Miners, and the Current evolution of neurobehavioral methods.

Marine Neurotoxins

1st Edition
Volume 6
July 13, 2021
Antonello Novelli + 3 more
English
Hardback
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eBook
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Marine Neurotoxins, Volume Five provides comprehensive information on marine toxins present in the human food chain and the affecting targets relevant for the functioning of the brain and our nervous system, covering all the information available on their action on the physiology of neurons and glial cells, both "in vivo" or "in vitro." New sections in this release include Guanidinium Toxins: Evolution, Mode of Action and Chemical Ecology, Amnesic: Domoic Acid, Neurotoxic: Ciguatoxin and Brevetoxin, Neurotoxic: Cyclic Imines, Potentially Neurotoxic: Okadaic acid and analogues, Potentially Neurotoxic: Palytoxin, and Methods for assessing the presence of marine neurotoxins.

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