Major advances in neurobiology and the clinical neurosciences have occurred in the past decade. Encyclopedia of the Neurological Sciences, Third Edition, Seven Volume Set, will cover and review all major areas of neuroscience and will be one of the few publications that can provide a complete overview of the neurological sciences in an easily accessible electronic format. All 21 sections and approx. 600 chapters will contain extensive supplemental links to useful references. Of special note are the new and paradigm shifting developments in genetics, immunology, molecular neurobiology, neuro-diagnostic tools and therapies for neurological disorders. This new edition will provide a thorough and easily accessible update in all areas of the neurological sciences. The sections and chapters will be written by internationally recognized experts from around the world and will be a valuable resource for all researchers, students and established scientists in the fields of neurology, psychiatry, and neurosurgery.
Circadian rhythms, sleep, and sleep disorders covers the topic in two sections focusing on basic science and clinical application. In the basic section, new developments and research findings focusing on basic circadian rhythm and sleep physiology in animals and humans is highlighted. The chapters are written in short mini-review formats in order to concisely describe the fundamentals, and current hot topics.The basic part starts with a chapter on the fundamentals and new discoveries on oscillating circuitries in the sleeping rodent and human brain. This sets the stage for chap 2, focusing on circadian and homeostatic aspects of human sleep regulation. Chap 3 extends these aspects to human cognition. The next chapter reports on visual and non-visual effects of light on human behavior, particularly endocrine and electrophysiological correlates. Chap 5 covers chronic sleep restriction effects on functional connectivity states. The last two chapters (6 and 7) give a broad overview on sleep modeling across physiological levels, with a focus on a quantitative model of sleep-wake dynamics based on the physiology of the brainstem ascending arousal system.The clinical section of the book describes the circadian rhythm sleep-wake disorders, from epidemiology to clinical picture and treatment. Disorders covered include delayed and advanced sleep phase syndrome, Irregular sleep-wake rhythm disorder, shift work disorder, restless legs syndrome, nocturnal eating syndrome, narcolepsy, and sleep apnea. Pharmacological and non-pharmacological treatments of insomnia are explored, as well as the role of sleep-wake modulation in the pathogenesis and clinical profile of neurodegenerative disorders, such as Parkinson’s disease and Alzheimer’s disease.
Coma, Stupor, and Related Disorders of Consciousness reviews recent research and best practice in the assessment and treatment of coma, stupor, and disorders of consciousness. It encompasses the neural circuits, anatomy & physiology of stupor and coma, differential diagnosis and clinical assessment, imagery, EEGs, therapy/intervention, decision making and prognosis.
Differentiating Factors in Alzheimer’s Disease: Gender, Ethnicity, Clinical and Treatment addresses the question why women differ from men in terms of their risk factors and how Alzheimer's disease can be prevented at the molecular level. This book reviews the epidemiology of Alzheimer's disease describing the differences in men's and women's brain anatomy and biochemistry that may account for why women are more likely to develop Alzheimer's disease. The authors offer actions that could help to prevent or slow the progression of Alzheimer's disease in addition to discussing the most recent pharmacological treatments.
In this issue of Neurologic Clinics, guest editor Dr. Alejandro A. Rabinstein brings his considerable expertise to the topic of Neurocritical Care. Top experts cover key topics in the field, including ICU delirium: a neurological perspective; prolonged monitoring of brain electrical activity in the ICU; AI applications in neurocritical care; brain injury after cardiac arrest: refining prognosis; advances in the critical care of ischemic brain infarction; and many more.