Brainstem
- 1st Edition - January 1, 2026
- Imprint: Elsevier
- Editors: Lea Tenenholz Grinberg, Amos D. Korczyn
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 5 7 3 6 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 5 7 3 7 - 0
This volume on Brainstem consolidates research for a complete understanding of the anatomy and physiology of the Brainstem and how it affects assorted other systems in the body.… Read more
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This volume on Brainstem consolidates research for a complete understanding of the anatomy and physiology of the Brainstem and how it affects assorted other systems in the body. The brainstem impacts breathing, the gastrointestinal system, the cardiac system, mood, pain, wakefulness, consciousness, and sleep. Pathologies can impact vision, motor control, hearing, balance, blood supply and is particularly involved in neurodegenerative diseases like Parkinson’s. The volume discusses how the brainstem operates in full health, pathologies associated with the brainstem and their impact, methods for monitoring brainstem function, and diagnosis and treatment of brainstem disorders. Monitoring and intervention is reliant on technologies to assess function. This volume will include CT, MRI, USG, angiography, BERA, and functional imaging.
- Presents brainstem anatomy and physiology
- Discusses brainstem impact on body systems
- Reviews techniques for brainstem monitoring
- Identifies brainstem pathologies and disorders
- Includes best practices for diagnosis and interventions
Practicing Clinical neurologists, research academic neurologists, Advanced students in med schools or neurology depts
Section 1: Physiology and semiology
1. Structural and Functional anatomy of the Brainstem
2. Autonomic Blood pressure control
3. Autonomic Respiratory control
4. Autonomic GI control
5. Autonomic heart control
6. Mood control
7. Pain control
8. The Brainstem monoaminergic systems (reticular formation)
9. Wakefulness, consciousness and sleep
Section 2: Pathology
10. Locked in syndrome (vascular and ND)
11. The vestibular system, equilibrium, vertigo, tinnitus
12. oculomotor disorders, nystagmus (all causes)
13. Pupillary disorders
14. BS syndromes
15. Intrinsic tumors of the Brainstem
16. Dysarthria
17. Brainstem in neurodegenerative diseases
18. Brainstem blood supply and vessel disorders
19. Neurodevelopmental issues of Brainstem
20. autoimmune
21. Trauma
Section 3: Monitoring and Intervention
22.. Anatomical imaging: CT
23. Anatomical imaging: MRI
24. Anatomical imaging: USG
25. Anatomical imaging: angiography
26. Physiological imaging, evoked response (BERA)- Vagus and auditory stimulations
27. Functional imaging
28. Brainstem monitoring
29. Brainstem death
1. Structural and Functional anatomy of the Brainstem
2. Autonomic Blood pressure control
3. Autonomic Respiratory control
4. Autonomic GI control
5. Autonomic heart control
6. Mood control
7. Pain control
8. The Brainstem monoaminergic systems (reticular formation)
9. Wakefulness, consciousness and sleep
Section 2: Pathology
10. Locked in syndrome (vascular and ND)
11. The vestibular system, equilibrium, vertigo, tinnitus
12. oculomotor disorders, nystagmus (all causes)
13. Pupillary disorders
14. BS syndromes
15. Intrinsic tumors of the Brainstem
16. Dysarthria
17. Brainstem in neurodegenerative diseases
18. Brainstem blood supply and vessel disorders
19. Neurodevelopmental issues of Brainstem
20. autoimmune
21. Trauma
Section 3: Monitoring and Intervention
22.. Anatomical imaging: CT
23. Anatomical imaging: MRI
24. Anatomical imaging: USG
25. Anatomical imaging: angiography
26. Physiological imaging, evoked response (BERA)- Vagus and auditory stimulations
27. Functional imaging
28. Brainstem monitoring
29. Brainstem death
- Edition: 1
- Published: January 1, 2026
- Imprint: Elsevier
- Language: English
LG
Lea Tenenholz Grinberg
Dr. Lea Tenenholz Grinberg is a neuropathologist specializing in brain aging and associated disorders, most notably, Alzheimer’s and neurological basis of sleep disturbances in neurodegenerative diseases. Currently, she is a Full Professor and a John Douglas French Alzheimer’s Foundation Endowed Professor at the UCSF Memory and Aging Center, part of the Executive Board of the Global Brain Health Institute and member of the Medical Scientific Advisory Group for the Alzheimer Association. She is also a Professor of Pathology at the University of Sao Paulo.
In 2003, Dr. Grinberg was among the founders of a brain bank in São Paulo, focusing on brain aging. This brain bank which she had since developed into an extremely prolific and highly-regarded institution, helped Dr. Grinberg prove that, contrary to what has been accepted previously, the brainstem and not the cortex, harbors the first detectable neurodegeneration in Alzheimer’s disease. In 2009, she was the recipient of the UNESCO-L'Oréal Award "For Women in Science," and in 2010 she received the John Douglas French Alzheimer Foundation "Distinguished Research Scholar Award." Currently, Dr. Grinberg is the Co-Leader of the UCSF/Neurodegenerative Disease Brain Bank, where she conducts neuropathological diagnosis of neurodegenerative diseases. She also directs the Human Biology Validation Core for the NIH/U54 Tau Centers Without Walls, is a principal investigator from the Tau
Affiliations and expertise
Full Professor and a John Douglas French Alzheimer’s Foundation Endowed Professor, UCSF Memory and Aging Center, BrazilAK
Amos D. Korczyn
Professor Korczyn graduated from the Hebrew University–Hadassah Medical School in Jerusalem in 1966 (MD), where he also received an MSc degree in pharmacology (cum laude) in 1966. He trained in neurology at Beilinson Hospital and at the National Hospital for Nervous Diseases, Queen Square, London. He was the Chairman of the Department of Neurology at the Tel-Aviv Medical Center from 1981 until 2002, and the incumbent of the Sieratzki Chair of Neurology at Tel-Aviv University, 1995-2010. Professor Korczyn has a particular interest in neurodegenerative diseases. He has authored or co-authored over 700 articles in peer-reviewed journals, edited several books and is Regional Editor of the Journal of Alzheimer’s Disease. He is or has been an Editorial Board member of 20 international journals, and organized several neurological conferences, mainly in the field of dementia, Parkinson’s disease and other degenerative brain disorders, as well as CONy – the International Congress on Controversies in Neurology, and has organized the Mental Dysfunction in Parkinson’s disease congresses since 1993. Professor Korczyn served on advisory boards in several drug discovery programs.
Professor Korczyn is the Chairman of the Scientific Medical Board of the Israeli Alzheimer’s disease association (EMDA), member of the SAB of Alzheimer Disease International (ADI), and has been the chairman of the WFN Research Committee for Clinical Neuropharmacology. Professor Korczyn is an honorary member of the neurological societies of Israel, Serbia, Poland, Russia, and Romania.
Affiliations and expertise
Sieratzki Chair of Neurology, Israel