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Books in Molecular neuroscience

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    • The Itch Spectrum

      • 1st Edition
      • Xinzhong Dong + 2 more
      • English
      "The Itch Spectrum: The Neurological and Immunological Basis of Itch and Dermatological Disorders" covers the latest research on the itch signalling pathway from the skin to the brain. With a multidisciplinary approach, this book will cover the mechanisms underlying the sensation of itch from the fields of neuroscience, immunology, genetics, and dermatology as they have intersected in the study of one somatosensory system. The purpose of this comprehensive reference is to summarize the revelatory discoveries in the field of itch and provide a comprehensive overview of what is known about this remarkable sensation and how various pathologies contribute to chronic pruritis.

    • Approaches for Brain Targeting Using Nanoparticulate Systems

      • 1st Edition
      • Bhagyashree V. Salvi + 2 more
      • English
      Approaches for Brain Targeting Using Nanoparticulate Systems aims to explore variety of nanoparticulate systems in the enhancement of therapeutic delivery, promotion for effective brain targeting, and reduction in the off-targets. Presenting the latest research, this book offers comprehensive insight into various nanosystems designed to overcome the blood brain barrier. This book presents the latest research on targeting approaches, physicochemical characteristics of nanoparticles, and the role of nanoparticles in enhancing the permeation of therapeutic systems across the blood brain barrier. Readers will also be able to develop a deeper understanding of how nanotherapeutics can revolutionize brain targeting through clinical applications.

    • The Molecular Neurobiology of Depression

      • 1st Edition
      • Subir Ranjan Kundu + 1 more
      • English
      The Molecular Neurobiology of Depression is a comprehensive reference covering the most up to date neurobiological evolution research in relation to suicide biology. This book explores the structural and functional traits of DNA, including non-coding DNA, in order to identify a genetic trigger of depression or suicidal behavior among individuals. This book intends to provide an in-depth perspective on the molecular footprints of the development of suicidal behavior of many individuals through case studies and an interdisciplinary approach.

    • Regulated Cell Death in Neurodegenerative Disorders

      • 1st Edition
      • Heba Mohamed Mansour + 1 more
      • English
      Regulated Cell Death in Neurodegenerative Disorders is a comprehensive exploration of the mechanisms and implications of RCD within the realm of neurodegenerative diseases. The book delves into various forms of RCD such as apoptosis, necroptosis, ferroptosis, pyroptosis, and autophagy-mediated cell death, shedding light on their specific roles in disorders like Alzheimer’s, Parkinson’s, Multiple sclerosis, Amyotrophic lateral sclerosis, and Huntington’s. Written by leading experts, each chapter offers unique insights into cellular demise, providing valuable information on treatment options and therapeutic targets. The book features 14 chapters that cover molecular, cellular, and pharmacological mechanisms from an applied science perspective.Topics include the importance of chaperones, kinases, growth factors, inflammaging, mitochondrial dynamics, and oxidative stress. It presents targeted strategies to prevent cell death, reflecting ongoing pursuits in understanding and innovating treatments for neurodegenerative diseases. By offering therapeutic strategies to modulate RCD, this book not only shares knowledge but also provides hope for future advancements in combating these debilitating conditions.

    • Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease, Seventh Edition

      Volume 1
      • 7th Edition
      • Volume 1
      • Roger N. Rosenberg + 1 more
      • English
      Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Seventh Edition, provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to neurologic and psychiatric disease. This volume has been thoroughly revised and includes newly commissioned chapters on ethics, genetic counselling and genet therapy for the central nervous system disorders. A favorite of over four generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the previous edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community at large.

    • Neuroscience Research in Short-Duration Human Spaceflight

      • 1st Edition
      • Bader Shirah
      • English
      Neuroscience Research in Short-duration Human Spaceflight encapsulates a groundbreaking neuroscience portfolio conducted during the Axiom Mission 2 in May 2023, offering an examination of the effects of short-duration orbital spaceflight on aspects of the human brain. Addressing limitations in existing literature, the research includes astronauts of diverse ages, genders, and ethnic backgrounds, broadening the understanding of the impact of spaceflight on human physiology. A significant aspect of the suite of studies is the validation of two novel devices providing unprecedented information about the pupillary light reflex and neuroimaging in microgravity: automated pupillometry and functional near-infrared spectroscopy. The portfolio extends to explore spaceflight-associat... neuro-ocular syndrome, offering valuable contributions to the evolving field of space medicine. Furthermore, the research delves into the utilization of electroencephalograp... to monitor brain activity, acknowledging its potential in assessing cognitive health, stress levels, and mental workload in real time. Despite promising prospects, challenges in electroencephalograp... system adaptability within the International Space Station environment are highlighted, emphasizing the need for specialized design considerations. In addition, analysis is extended into the molecular biomarkers through minimally invasive blood monitoring. This book represents a pivotal advancement in space neuroscience, laying the foundation for safer space travel and fostering the development of monitoring tools crucial to observing adverse changes and potentially developing countermeasures that can aid in the establishment of a permanent human presence beyond Earth.

    • Integrative Omics in Parkinson's Disease

      • 1st Edition
      • Joanne Trinh
      • English
      Integrative Omics in Parkinson’s Disease provides a comprehensive understanding of the current literature on high-throughput technologies relating to discoveries for Parkinson's disease etiology. This emerging field uses large omics datasets to investigate the etiology of Parkinson’s disease and other forms of parkinsonism. The book traces the evolution of omics technologies from the discovery of monogenic Parkinson's disease forms. Chapters delve into genomics, transcriptomics, epigenomics, artificial intelligence, and gene-environment interactions. Furthermore, it examines the potential therapeutic applications of these advancements and provides insights into the future of omics research in Parkinson's disease.

    • From Brain Dynamics to the Mind

      Spatiotemporal Neuroscience
      • 1st Edition
      • Georg Northoff
      • English
      From Brain Dynamics to the Mind: Spatiotemporal Neuroscience explores how the self and consciousness is related to neural events. Sections in the book cover existing models used to describe the mind/brain problem, recent research on brain mechanisms and processes and what they tell us about the self, consciousness and psychiatric disorders. The book presents a spatiotemporal approach to understanding the brain and the implications for artificial intelligence, novel therapies for psychiatric disorders, and for ethical, societal and philosophical issues. Pulling concepts from neuroscience, psychology and philosophy, the book presents a modern and complete look at what we know, what we can surmise, and what we may never know about the distinction between brain and mind.

    • Natural Molecules in Neuroprotection and Neurotoxicity

      • 1st Edition
      • Marcos Roberto de Oliveira
      • English
      Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This two volume set is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-relat... strategies utilized in neuroprotection.Writ... by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of action and possible clinical applications. This set provides an essential reference for researchers and clinical scientists interested in the effects of natural compounds on the human health and disease.

    • Nutrition and Neurological Disorders

      • 1st Edition
      • Colin R. Martin + 2 more
      • English
      Nutrition and Neurological Disorders offers readers a comprehensive reference on the effect of dietary regimes in a wide variety of neurological diseases. With its broad coverage of different types of diets, including the Mediterranean diet, this book allows readers to learn about the results of diets and their correlation with specific disorders. This includes diseases such as Alzheimer’s, Parkinson’s, ALS, and MS and severe neurological conditions such as brain injury, stroke, headache and migraine. Examining various compounds, the book's broad coverage allows readers to learn more about the role nutrient deficiency plays in the pathology of many conditions, along with treatment potential. This volume provides a platform for research on vitamins and minerals and on future investigations of these compounds.