Neural aging print books and ebooks | Elsevier

Neurobiology of Aging

1st Edition
December 1, 2025
Sachchida Nand Rai
English
eBook
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Neurobiology of Aging: Exploring Cognitive Decline and Neurodegeneration is a comprehensive reference exploring the complexities of the aging brain. This book examines the intricate processes driving cognitive decline and neurodegeneration. From the gradual loss of neurons and synapses to the formation of protein aggregates characteristic of Alzheimer's disease, each chapter reviews key aspects of brain aging. Chapters dissect the mechanisms driving neuronal loss, synaptic dysfunction, and protein misfolding, shedding light on the intricate interplay of oxidative stress, inflammation, and mitochondrial dysfunction. This book also navigates through strategies for healthy brain aging, from the impact of diet and exercise to the role of cognitive stimulation.

Age-Related Hearing Loss, Brain Health, and Dementia

1st Edition
November 1, 2025
Helen E. Nuttall + 2 more
English
Paperback
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eBook
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Age-Related Hearing Loss, Brain Health, and Dementia reviews the effects of hearing loss on the brain and examines the most up-to-date perspectives on the possible causal relation between hearing loss and cognitive impairment. Through this synthesis, the book explores the links between hearing loss and the brain to improve understanding and promote better hearing for better brain health.

Alzheimer's Disease Research Guide

1st Edition
July 25, 2024
Takaomi C. Saido
English
Paperback
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eBook
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Alzheimer's Disease Research Guide: Animal Models for Understanding Mechanisms and Medications provides researchers with a comprehensive guide, detailing every aspect of Alzheimer's Disease research, including chapters on neuroinflammation, immunotherapy, biomarkers, and animal modeling. This book begins with historical perspectives of both pathological chronology and pathological biochemistry in relation to Alzheimer’s disease. Other chapters review Amyloidogenic AB and Non-Amyloidogenic tau and Metabolism of AB major components to the research and understanding of Alzheimer’s research. The book concludes with specific treatment chapters including how to develop safe, effective, and inexpensive medications and the application of genome editing to the treatment of Familial Alzheimer's Disease.Written by world renowned expert in Alzheimer’s research, this book is a valuable resource for all researchers.

Loneliness in Older Adults

1st Edition
June 1, 2022
Luis Miguel Rondon Garcia
English
Paperback
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eBook
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Loneliness in Older Adults: Effects, Prevention, and Treatment analyzes loneliness as a complex phenomenon, taking into account the most recent contributions from neuroscience, psychology, medicine and sociology. This volume describes this phenomenon from an interdisciplinary point of view, with special emphasis on older people from a plural and heterogeneous perspective: older people in general, older immigrants, older women, older LGTBI, etc. Faced with the impact of this emerging issue, this book provides a comprehensive knowledge of loneliness, contributing scientific knowledge to the practice of evidence. Tools are also provided for professionals, providing intervention protocols with debates and proposals, and effective digital resources to combat it. Tables, images, and tools guide students, academics, and professionals step-by-step in solving the cases raised, through an integrated practice. There is no work that develops this theme from such a plural and pragmatic perspective, covering all the dimensions of loneliness in each of the thematic axes: psychological, neurological, social, and health. Readers are provided feedback for all the knowledge for a comprehensive scientific knowledge based on evidence and given the necessary instrumental skills related to being social and the functioning of our brain. This book is aimed at a very plural audience of researchers, academics and professionals in the social and behavioral sciences including psychologists, sociologists, social workers, anthropologists, and also professionals in the health sciences, among others.

The Neuroscience of Aging

1st Edition
June 25, 2021
Colin R. Martin + 2 more
English
Paperback
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Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging is a comprehensive reference on the diagnosis and management of neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. It also examines pharmacological and non-pharmacological interventions of age-related conditions that affect the brain including Alzheimer’s, stroke, and multiple sclerosis. Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. It also examines the use of animal modelling of aging and neurological disease.

Factors Affecting Neurological Aging

1st Edition
June 1, 2021
Colin R. Martin + 2 more
English
Hardback
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eBook
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Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. Finally, this comprehensive resource examines the use of animal modeling of aging and neurological disease.

Neurochemical Aspects of Alzheimer's Disease

1st Edition
May 25, 2017
Akhlaq A. Farooqui
English
Paperback
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eBook
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Neurochemical Aspects of Alzheimer's Disease provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies. The book focuses on molecular mechanisms and signal transduction processes associated with the pathogenesis, biomarkers, and therapeutic strategies of AD. The comprehensive and cutting edge information in this monograph may not only help in early detection of AD, but also promote discovery of new drugs to treat this chronic disease. Chapters discuss involvement of neural membrane phospholipids, sphingolipids, and cholesterol-derived lipid mediators, abnormal APP processing, and nucleic acid damage, risk factors, biomarker, and therapeutic strategies of Alzheimer's disease. This book is written for neurologists, neuroscientists, neurochemists, neuropharmacologists... and clinicianswho are interested in molecular mechanisms associated with the pathogenesis of age-related neurological disorders.

The Neuroendocrine Immune Network in Ageing

1st Edition
Volume 4
July 24, 2004
R.H. Straub + 1 more
English
eBook
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The book describes the mechanisms involved in the maintenance of neuroendocrine-immun... interactions in ageing. The lack of this maintenance leads to the appearance of age-related diseases (cancer, infections, dementia) and subsequent disability. The capacity of some hormones or nutritional factors in restoring and remodelling the neuroendocrine-immun... response during ageing is reported presenting possible new anti-ageing strategies in order to reach healthy ageing and longevity.

Functional Neurobiology of Aging

1st Edition
December 15, 2000
Patrick R. Hof + 1 more
English
Hardback
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eBook
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Some well-known age-related neurological diseases include Parkinson's disease, Alzheimer's disease, deafness, and blindness. Even more common are the problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging continue to become more common, and conditions associated with aging need more attention by doctors and researchers. In 1991, patients over the age of 65 saw their doctors an average of eight times per year. Research funding is provided by the Neuroscience and Neuropsychology of Aging (NNA) Program, which is run by the National Institute on Aging. This book offers a comprehensive overview of all topics related to functional impairments which are related to the aging brain and nervous system. It is organized according to four general functions: movement, senses, memory, and neuroendocrine regulation. Written by the leading researchers in the field, this comprehensive work addresses both impairments associated with diseases and not associated with diseases, making it easier to understand the mechanisms involved. Functional Neurobiology of Aging is an important reference for professionals and students involved in aging research, as well as physicians who need to recognize and understand age-related impairments.

Handbook of the Aging Brain

1st Edition
July 21, 1998
Eugenia Wang + 1 more
English
Hardback
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eBook
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Handbook of the Aging Brain brings together diverse scientific disciplines to cover the most recent research findings in an easy-to-read summary. Scientists and clinicians will find a wide spectrum of subjects including gerontology, neurology, psychology, molecular biology, and cellular biology. The book includes general chapters on the neuroanatomy and neurobiology of the aging brain, and moves on to discussion of specifics including signal transduction, cell death, and specific cellular and neurological changes associated with dementia, Alzheimer's and Parkinson's Disease. Other chapters discuss the affect of aging on learning and memory, language, and cognition.

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