Cell and Gene Therapies for Neurologic Diseases

1st Edition, Volume 205 - October 1, 2024
Editors: Howard J. Federoff, Roger A. Barker
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 9 0 1 2 0 - 8
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 0 1 2 1 - 5

Cell and Gene Therapies for Neurologic Diseases, Volume 205 comprehensively covers the scientific background, translational efforts, clinical developments and registered biolog… Read more

Purchase options

LIMITED OFFER

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code is needed.

Institutional subscription on ScienceDirect

Request a sales quote

Cell and Gene Therapies for Neurologic Diseases, Volume 205 comprehensively covers the scientific background, translational efforts, clinical developments and registered biologics that have entered into clinical practice. Coverage includes types of therapies available and in development, and best practice uses for a variety of neurological disorders including Parkinson’s, Huntington’s, ALS, stroke, spinal cord RP, demyelination, and epilepsy. As the emergence of gene and cellular therapeutics has changed the clinical landscape for a variety of disorders, and is now ready to do so for neurological diseases, these therapeutic modalities currently complement, and may in time, supplant small molecule drugs.

Howard J. Federoff

Howard Federoff, M.D., Ph.D., has a dual role of Vice Chancellor for Health Affairs and the CEO of UCI Health System. As Vice Chancellor for Health Affairs, Dr. Federoff has responsibility for the clinical, medical educational, and research missions. As CEO of UC Irvine Health System, Dr. Federoff oversees the administration of clinical locations, UC Irvine Medical Center, the Chao Family Comprehensive Cancer Center, and UC Irvine Health’s primary and specialty care outpatient centers. A nationally renowned clinical and research leader and a groundbreaking investigator for neurological disorders, Dr. Federoff’s research led to a new gene therapeutic trial in Parkinson’s disease, in predicting the onset of Alzheimer’s disease. Dr. Federoff has an academic appointment in the department of Neurology. He has published 250+ articles, serves as a reviewer for many journals, and serves on the editorial boards of five journals. Dr. Federoff served as Chair of the NIH Recombinant DNA Advisory Committee from 2007-2010. He Chaired the Gene Therapy Resource Program for NHLBI (2010-2016), was President for the American Society for Neural Therapy and Repair (2012-2013) and President of the American Society for Experimental Neurotherapeutics (2014-2016). He is chair-elect of the Association of Academic Health Centers (AAHC) Board. Dr. Federoff is an elected Fellow of the American Association for the Advancement of Science and the National Academy of Inventors.

Affiliations and expertise

Vice Chancellor for Health Affairs, UCI Health System, The City Drive South, Orange, California, United States of AmericaCEO, UCI Health System, UCI Health System, The City Drive South, Orange, California, USA

Roger A. Barker

Roger Barker is the Professor of Clinical Neuroscience and Honorary Consultant in Neurology at the University of Cambridge and at Addenbrooke's Hospital.  He trained at Oxford and London and has been in his current position since 2000, after completing an MRC Clinician Scientist Fellowship. Dr. Barker combines basic research looking at novel therapies to treat chronic neurodegenerative disorders of the brain with clinically-based work aimed at better defining such disorders. He is the co-ordinator of the TRANSEURO project looking at fetal cell grafting in patients with early Parkinson's Disease and is part of the GFORCE PD initiative as well as Director of the ISSCR.

Affiliations and expertise

Professor of Clinical Neuroscience, University of Cambridge, Cambridge, England, United KingdomHonorary Consultant, Addenbrooke's Hospital, Cambridge Biomedical Campus, Cambridge, UK