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Books in Neurochemistry

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Neurobiology of Infectious Diseases

  • 1st Edition
  • Volume 1
  • November 30, 2024
  • Tatiana Barichello + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 9 1 3 0 - 5
Neurobiology of Infectious Diseases covers mechanisms underlying infectious diseases. It is divided into six distinct sections, beginning with the foundations of Neuroinfection. This section includes chapters on the role microbiota-gut-brain axis and specialized blood-neuronal barriers play in neurobiology of infectious diseases. The next three sections detail various bacterial infections, parasitic infections, viral infections, and fungal infections of the central nervous system. The last section reviews the proteins and other peripheral mediators that affect the central nervous system. Internationally contributed by experts in the field this book sets the foundation of neurobiology and infectious disease.Neurobiology is the study of cells of the nervous system and the organization of these cells into functional circuits that process information and mediate behavior. Current research is vital for determining pharmaceutical and medicinal treatments for neurological disorders, psychiatric disorders and diseases.

Ayurvedic Herbal Preparations in Neurological Disorders

  • 1st Edition
  • August 7, 2023
  • Murali Muralidhara + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 9 0 8 4 - 1
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 3 9 6 - 9
Ayurvedic Herbal Preparations in Neurological Disorders provides a comprehensive and mechanistic understanding of the therapeutic potential of many ayurvedic herbal preparations in disease management. Examining research data for evidence-based ayurvedic approaches, this volume begins with a focused introduction to major ayurvedic plants, discussing various mechanisms underlying their neuromodulatory potential in preclinical and clinical settings. Major subsets of ayurvedic plants are discussed, including Bacopa monnieri, Centella asiatica, Withania somnifera, and others. This volume outlines the importance of integrative approaches along with existing treatments in the intervention/management of Alzheimer’s disease, Parkinson’s disease, depressive mood disorders, epilepsy, schizophrenia, and more. More than a mere compilation of studies, this volume identifies relevant gaps for future research avenues and encourages interdisciplinary collaboration and sharing of knowledge to together identify the most efficacious ayurvedic approaches. Highlighting recent developments (e.g., Ayurgenomics, Ayurahar) and other pertinent research for neuroprotection, this book is crucial for anyone researching or working in the field of neurological disorder treatment and prevention.

Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders

  • 1st Edition
  • June 6, 2023
  • Heba Mohamed Mansour + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 8 6 7 7 - 6
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 8 6 7 8 - 3
Overexpression of receptor tyrosine kinases (RTKs) has been implicated in cancer. Increasing evidence suggests that dysregulation of RTKs is reported in many neurodegenerative and psychiatric disorders. Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders provides a fundamental, pragmatic map of RTKs structure, activation, functions, mechanism of action, gene regulation, and signaling pathways in developing central nervous system (CNS), adult normal CNS, neurodegenerative and psychiatric disorders. Additionally, the structure, function, activation, and therapeutic potential of many growth factors have been covered. Here, international experts in the field offer a comprehensive discussion of results of pre-clinical and clinical studies of repositioning of anti-cancer receptor tyrosine kinase inhibitors (RTKIs) and other promising protein kinase inhibitors in various neurodegenerative disorders including, Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis, and psychiatric disorders including, anxiety, depression, alcohol use disorder, and schizophrenia. In addition, the book discusses the obstacles and opportunities for the potential repositioning of kinase inhibitors in neurodegenerative and psychiatric disorders.

Nicotinic Acetylcholine Receptors in Health and Disease

  • 1st Edition
  • March 14, 2023
  • R. Thomas Boyd
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 9 9 5 8 - 9
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 0 4 1 8 - 4
Nicotinic Acetylcholine Receptors in Health and Disease provides the latest information Nicotinic acetylcholine receptors (nAChRs), which are involved in numerous diseases, including Alzheimer’s, Parkinson’s, and schizophrenia, and are important potential translational targets for treatment of these diseases, as well as therapy for addiction. This book focuses on the roles and function of nAChRs inside and outside of the nervous system, with an emphasis on translational implications and future prospects for the treatment of numerous disorders. This greater understanding of the basic neurobiology and clinical roles of nAChRs provides important insights for future clinical treatments of many major disorders.

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases

  • 1st Edition
  • December 3, 2021
  • Anil Gupta
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 0 1 2 2 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 0 4 4 3 - 6
Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases elucidates elaborately the role of caspase enzymes implicated in the initiation of molecular events leading to neuronal apoptosis in the neurodegenerative disease. The book starts with introduction to neuropathology, neurogenetics, and epidemiology of neurodegenerative disease and illustrates the involvement of human caspases, neuronal apoptosis, apoptotic pathways, genetic polymorphisms, and several other factors and underlying mechanisms in the pathology of Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease. An important focus in all chapters is the intricate mechanisms and interplay that occur during or leading to neuron death in neurodegenerative diseases, along with disease pathobiology.

Handbook of the Behavioral Neurobiology of Serotonin

  • 2nd Edition
  • Volume 31
  • January 21, 2020
  • Christian P. Muller + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 6 4 1 2 5 - 0
  • eBook
    9 7 8 - 0 - 4 4 4 - 6 4 1 2 6 - 7
Handbook of the Behavioral Neurobiology of Serotonin, Second Edition, builds on the success of the first edition by continuing to provide a detailed and comprehensive overview of the many facets of behavioral serotonin research. The text expands on the two key topics, behavioral control (sensory processing, ultrasonic vocalization, and melatonin and sleep control) and psychiatric disorders, including its role on psychostimulant abuse and addiction. The new edition includes two new sections on the serotonin systems interactions and the involvement of serotonin in neurological disorders and associated treatment. Serotonin is a major neurotransmitters in the serotonergic system which one of the best studied and understood transmitter systems. Both are critically involved in the organization of all behaviors and in the regulation of emotion and mood.

Molecular Mechanisms of Dementia

  • 1st Edition
  • April 15, 2019
  • Akhlaq A. Farooqui
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 6 3 4 7 - 4
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 6 7 3 1 - 1
Considerable progress has been made in neurochemical and therapeutic aspects of dementia research in recent years. Molecular and Therapeutic Aspects of Dementia presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of dementias. It provides a clearly written and logically organized and comprehensive overview of molecular aspects of risk factors, symptoms, pathogenesis, biomarkers, and therapeutic strategies for various types of dementia. This book is written for the international audience of neurochemists, neuroscientists, neurologists, neuropharmacologists, and clinicians. The hope is that this discussion will not only integrate and consolidate knowledge in this field, but will jumpstart more studies on molecular mechanisms and therapeutic aspects of dementia. The comprehensive information in this monograph may not only help in early detection of various types of dementia and dementia linked neurological disorders, but also promote discovery of new drugs, which may block or delay the onset of dementia in elderly patients. Understanding the course of dementia is important not only for patients, caregivers, and health professionals, but also for health policy-makers, who have to plan for national resources needed in the management of an increasing number of dementia cases.　

Neurochemical Aspects of Alzheimer's Disease

  • 1st Edition
  • May 25, 2017
  • Akhlaq A. Farooqui
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 0 9 9 3 7 - 7
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 9 9 3 8 - 4
Neurochemical Aspects of Alzheimer's Disease provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies. The book focuses on molecular mechanisms and signal transduction processes associated with the pathogenesis, biomarkers, and therapeutic strategies of AD. The comprehensive and cutting edge information in this monograph may not only help in early detection of AD, but also promote discovery of new drugs to treat this chronic disease. Chapters discuss involvement of neural membrane phospholipids, sphingolipids, and cholesterol-derived lipid mediators, abnormal APP processing, and nucleic acid damage, risk factors, biomarker, and therapeutic strategies of Alzheimer's disease. This book is written for neurologists, neuroscientists, neurochemists, neuropharmacologists, and clinicianswho are interested in molecular mechanisms associated with the pathogenesis of age-related neurological disorders.

Blanco's Overview of Alpha-1 Antitrypsin Deficiency

  • 1st Edition
  • April 28, 2017
  • Ignacio Blanco
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 9 5 3 0 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 9 5 4 1 - 6
Blanco’s Overview of Alpha-1 Antitrypsin Deficiency: History, Biology, Pathophysiology, Related Diseases, Diagnosis, and Treatment is a robust introduction to topics associated with Alpha-1 Antitrypsin Deficiency (AATD). Included are topics ranging from the history of the disease, biology, pathophysiology, related diseases, including the two major manifestations of the disease (liver disease and lung disease), and diagnosis and treatment. The book addresses the need for the amalgamation of current and novel concepts and practices in the field of AATD. AATD is under-recognized in the medical community and, as a result, it is underdiagnosed. The book provides increased awareness and understanding of the condition to improve diagnosis rates and enhance patient care. This book is an essential tool and reference, beneficial to clinicians who screen and treat AATD patients, as well as research scientists working in the AATD field at junior and senior levels.

DNA Modifications in the Brain

  • 1st Edition
  • December 23, 2016
  • Timothy W Bredy
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 0 1 5 9 6 - 4
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 1 7 8 1 - 4
DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease.