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Handbook of the Behavioral Neurobiology of Serotonin, Second Edition, builds on the success of the first edition by continuing to provide a detailed and comprehensive overview… Read more
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Handbook of the Behavioral Neurobiology of Serotonin, Second Edition, builds on the success of the first edition by continuing to provide a detailed and comprehensive overview of the many facets of behavioral serotonin research. The text expands on the two key topics, behavioral control (sensory processing, ultrasonic vocalization, and melatonin and sleep control) and psychiatric disorders, including its role on psychostimulant abuse and addiction. The new edition includes two new sections on the serotonin systems interactions and the involvement of serotonin in neurological disorders and associated treatment.
Serotonin is a major neurotransmitters in the serotonergic system which one of the best studied and understood transmitter systems. Both are critically involved in the organization of all behaviors and in the regulation of emotion and mood.
Section 1: Functional anatomy of the serotonergic system
1.1 Evolution of serotonin: sunlight to suicide
Efrain C. Azmitia
1.2 From B1 to B9: a guide through hindbrain serotonin neurons with additional views from multidimensional characterization
Mariano Soiza-Reilly and Patricia Gaspar
1.3 Serotonin System Function, Organization and Feedback
Kathryn G. Commons
1.4 Ultrastructure of the serotonin innervation in mammalian central nervous system
Martin Parent and Laurent Descarries
1.5 Classification and Signaling Characteristics of 5-HT Receptors: Towards the Concept of 5-HT Receptosomes
Philippe Marin, Carine Bécamel, Séverine Chaumont-Dubel, Franck Vandermoere, Joël Bockaert, and Sylvie Claeysen
1.6 Distribution of 5-HT receptors in the central nervous system: An update
M. Teresa Vilaró, Roser Cortés, Guadalupe Mengod, and Daniel Hoyer
1.7 The serotonin2B receptor and neurochemical regulation in the brain
Umberto Spampinato, Adeline Cathala, and Céline Devroye
1.8 Electrochemical Detection of Serotonin Release in Rodents
Rhiannon Robke, Aishwarya Parthasarathy, Ingo Willuhn, and Parastoo Hashemi
1.9 Molecular neuroimaging of the serotonergic system with Positron Emission Tomography
Silberbauer L, James GM, Spies M, Michenthaler P, Kranz GS, Kasper S, and Lanzenberger R
Section 2: The neurophysiology of serotonin
2.1 Serotonergic control of excitability: from neuron to networks
Giuseppe Di Giovanni, Abdeslam Chagraoui, Rahul Bharatiya, and Philippe De Deurwaerdère
2.2 Structure and function of serotonin GPCR heteromers
Urjita Shah, Hanna Pincas, Stuart C. Sealfon, and Javier González-Maeso
2.3 Tryptophan hydroxylase and serotonin synthesis regulation
Donald M. Kuhn and Hiroyuki Hasegawa
2.4 Serotonylation and neuronal function
Nancy A. Muma and Khushboo Kapadia
2.5 The effects of serotonin degradation on psychopathology: Role of monoamine oxidase
Gabriele Floris, Roberto Cadeddu, and Marco Bortolato
2.6 Cellular effects of serotonin in the CNS
Rodrigo Andrade and Samir Haj-Dahmane
2.7 Serotonin - lipid interactions and their role in behavior
Liubov S. Kalinichenko, Erich Gulbins, Johannes Kornhuber, Christian P. Müller
2.8 Serotonin – Pain Modulation
Volker Neugebauer
2.9 Serotonin regulation of striatal function
Sunila G. Nair, Melissa M. Estabrook, and John F. Neumaier
2.10 Serotonergic regulation of hippocampal rhythmical activity
Robert P. Vertes and Stephanie B. Linley
2.11 The loudness dependence of auditory evoked potentials as an electrophysiological marker of central serotonergic neurotransmission: implications for clinical psychiatry and psychopharmacotherapy
Patrik Roser, Wolfram Kawohl, and Georg Juckel
Section 3: Serotonin and systemic control
3.1 5-HT neurons and central CO2 chemoreception
Frida A. Teran and George B. Richerson
3.2 Serotonin: a forgotten signal from the blood
Paul M. Vanhoutte
Section 4: Serotonin and behavioural control
4.1 Serotonin and development
Patricia M. Whitaker-Azmitia
4.2 Roles of serotonin in the fetal brain
Qiuying Zhao and Alexandre Bonnin
4.3 Serotonin and sensory processing
Mariana M. Marquez and Maurice J. Chacron
4.4 Serotonin and basal sensory–motor control
Robert J. Carey
4.5 Role of the serotonergic system in appetite and ingestion control
Michelle D. Lee and Peter G. Clifton
4.6 Serotonin in eating behavior
Valérie Compan
4.7 Serotonin and the neurobiology of anxious states
Adam J. Lawther, Matthew W. Hale, and Christopher A. Lowry
4.8 Dorsal raphe serotonergic neurons regulate behavior on multiple timescales
Jeremiah Y. Cohen and Cooper D. Grossman
4.9 The role of central serotonin in impulsivity, compulsivity and decision-making: Comparative studies in experimental animals and humans
B.U. Phillips and T.W. Robbins
4.10 The role of serotonin in learning and memory: a rich pallet of experimental studies
Jean-Christophe Cassel
4.11 The role of serotonin in performance monitoring and cognitive control
Adrian G Fischer and Gerhard Jocham
4.12 Serotonin and 5-HT2B receptors in microglia control of behavior
Ivana D'Andrea, Catherine Béchade, and Luc Maroteaux
4.13 The serotonin-free brain: behavioural consequences of Tph2 deficiency in animal models
Valentina Mosienko, Michael Bader, and Natalia Alenina
Section 5: Serotonin in psychiatric disorders
5.1 Serotonin in panic and anxiety disorders
Hélio Zangrossi Jr., Cristina Marta Del Ben, Frederico Guilherme Graeff, and Francisco Silveira Guimarães 5.2 Serotonin and aggression – An update
Isabel M. Quadros, Aki Takahashi, and Klaus A. Miczek
5.3 Revisiting the Behavioral Genetics of Serotonin: Relevance to Anxiety and Depression
Olivia F. O’Leary, Martin G. Codagnone, and John F. Cryan
5.4 Serotonin and schizophrenia
Boris B. Quednow, Mark A. Geyer, and Adam L. Halberstadt
5.5 Serotonin neurobiology in cocaine use disorder
Kathryn A. Cunningham, Leonard L. Howell, and Noelle C. Anastasio
5.6 The role of serotonin in alcohol use and abuse
Christian P. Müller, Gunter Schumann, Johannes Kornhuber, and Liubov S. Kalinichenko
5.7 The role of serotonin in nicotine abuse and addiction
Małgorzata Filip, Irena Smaga, and Edmund Przegaliński
5.8 Serotonin and serotonin receptors in hallucinogen action
Adam L. Halberstadt and David E. Nichols
5.9 The serotonergic system in obsessive compulsive disorder
Maik Derksen, Matthijs Feenstra, Ingo Willuhn, and Damiaan Denys
5.10 Peripheral and central serotonin in the regulation of glucose metabolism
Mireille J Serlie
5.11 The role of serotonin in cortical development: implications for Autism Spectrum Disorder
Christine F. Hohmann, Mary S. Lange, and Mary E. Blue
5.12 Genetic, epigenetic, and environmental factors in serotonin associated disease conditions
Eva Friedel and Andreas Heinz
5.13 Functional pharmacogenetics of serotonin receptors in psychiatric drug action
Olga O. McGowan and Gavin P. Reynolds
5.14 Classic psychedelics as therapeutics for psychiatric disorders
Charles D. Nichols and Peter S. Hendricks
Section 6: Serotonin in neurological disorders
6.1 Serotonin in Parkinson's disease
Zacharias Kohl and Jürgen Winkler
6.2 Serotonin in seizures and epilepsy: a neurodevelopmental perspective
Yuri Bozzi, Giacomo Maddaloni, and Massimo Pasqualetti
6.3 Serotonin and stroke
Jong S. Kim
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