Nutritional Neuroscience
From Bench to Bedside
- 1st Edition - January 23, 2026
- Latest edition
- Editors: Reinaldo B. Oria, Joao O. Malva, Carlos Alexandre Netto
- Language: English
Nutritional Neuroscience: From Bench to Bedside navigates the complex connections between nutrition and neurological health, from neurodevelopmental disorders influenced by… Read more
Nutritional Neuroscience: From Bench to Bedside navigates the complex connections between nutrition and neurological health, from neurodevelopmental disorders influenced by early-life malnutrition to the neuroprotective effects of functional foods. Each chapter offers a detailed examination of the latest research in the field, spanning the mechanisms of taste and food processing in the brain, the impact of dietary interventions on inflammation and blood–brain barrier function, and the link between metabolic disorders and neurodegenerative diseases. This book sits at the forefront of nutritional neuroscience, where cutting-edge research meets practical application, and equips its readers with a holistic understanding of how nutrition influences brain health at all ages. Bridging the gap between laboratory discoveries and clinical practice, this book offers a roadmap for future research and interventions in the f ield of nutritional neuroscience.
• Highlights the influence of nutritional disorders on nervous system development
• Describes sensory, cerebral, and endocrine function in the regulatory processes of eating behaviors
• Covers the relationship between the central nervous system, enteric nervous system, and intestinal microbiota
• Explains how intestinal microbiota influences the body’s homeostasis and neuroinflammation
• Describes sensory, cerebral, and endocrine function in the regulatory processes of eating behaviors
• Covers the relationship between the central nervous system, enteric nervous system, and intestinal microbiota
• Explains how intestinal microbiota influences the body’s homeostasis and neuroinflammation
Neuroscientists, nutritionists, clinicians in applicable fields, researchers, graduate and advance students
1. Neurodevelopmental disorders related to prenatal and early life exposure to malnutrition
Luís F. Grilo, Sandra I. Mota, Laura A. Cox, Paulo J. Oliveira and Carol Shively
2. Taste, olfactory, and food processing in the brain
Edmund Rolls
3. Maternal nutrition and epigenetic consequences for offspring cognition
Hércules R. Freitas, Ricardo A.M. Reis, Belmira L.S. Andrade-da-Costa and Isis H. Trevenzoli
4. Neurobiological programming of hedonic eating behavior
Randriely Merscher Sobreira de Lima, Patrícia Pelufo Silveira, Carla Dalmaz, Angela Marcela Jaramillo
Ospina and Rachel Krolow S.S. Bast
5. Neuroendocrine controls of appetite and satiety
Marcella Duarte Villas Mishima, Andressa Ladeira Bernardes, Luisa Lana, Łukasz Grześkowiak and Maria Do Carmo Gouveia Peluzio
6. Enteric nervous system and nutrition
Patricia Castelucci, Marcos Antônio Ferreira Caetano and Paulo Correia-de-Sá
7. Dietary modulation of gut microbiota and gut–brain axis Sofia Viana, Carolina Ferreira, Cristiana Violante, Maria Dolores Hinchado and Flávio Reis
8. Adipose tissue, adipokines, and neuroinflammation
Barbara Moura Antunes, Daniela Sayuri Inoue and Fabio Santos Lira
9. Diet, brain, and mental health
Yohannes Adama Melaku, Tefera Chane Mekonnen, Zegeye Abebe and Zumin Shi
10. Functional foods and nutraceuticals as neuroprotectors
Carolina Ferreira, Pedro Vieira, Eduardo Ortega Rincón, Flávio Reis and Sofia Viana
11. Neurosciences of sleep and nutrition
Camila Goncalves Monteiro Carvalho, Danielle Mesquita Torres, José Wagner Leonel Tavares- Júnior, Manoel Alves Sobreira-Neto and Pedro Braga-Neto
12. Food toxicants and brain health
Elena Efremenko
13. Dietary interventions and brain health
Sanika M. Joshi, Riley McCabe and Nafisa M. Jadavji
14. Understanding nutrition beyond calories and vitamins—why plants are beneficial
Megan F. Lee and Maximilian Andreas Storz
15. Omega-3 fatty acids may boost heart health in people with Parkinson’s disease
Fulvio Alexandre Scorza, Rozana Mesquita Ciconelli, Josef Finsterer, Feres Chaddad-Neto and Carla Alessandra Scorza
16. Neuroprotection and antiageing effects of caloric restriction
Roberto A. Dias, Catarina Mendes, Nuno Raimundo and Neuza Domingues
17. Neurovascular dysfunction, stroke, and age-related cognitive impairment: the benefits of the Mediterranean diet
Alexandros Zabetakis, Ioannis Zaganas, Ana Duarte, Débora Mena, Eliane Sanches and Joa ~o Malva
18. Hypercaloric diet, inflammation, and blood–brain barrier dysfunction
Filipa Isabel Baptista, Joana Margarida Gaspar, Catarina Muralha Leiria, Ana Rita Garcia, Maria Alexandra Brito and Ana Paula Silva
19. Nutrigenomics and nutrigenetics in neurological disorders
Iokasti Lazidou, Gerasimos Iordanis, Pinelopi Eleni Petrocheilou, George P. Patrinos and George Lagoumintzis
20. Neuroendocrine and nutritional disorders
Manoel Martins, Andrea Glezer, Carolina Garcia Soares Lea ~es Rech and Synara Lopes
21. Meal patterns and cognitive health in adulthood
Dora Brikou, Dimitra Dimopoulou, Nikolaos Scarmeas and Mary Yannakoulia
22. Dietary intervention, stress, and neuropsychiatric disorders
Maria Francilene Silva, Fátima de Cássia Evangelista Oliveira, Sergio Andre de Souza Junior, Pharm Tatiana Barichello and Danielle S. Macedo
23. Neurogenesis impairment in hypercholesterolemia: a potential contributor to cognitive decline and depression
Andreza Fabro de Bem, Hémelin Resende Farias, Daiane Fátima Engel, Patrícia de Souza Brocardo and Jade de Oliveira
24. Energy metabolism and mitochondrial dynamics in neurodegenerative disorders: focus on hyperhomocysteinemia and neonatal hypoxia-ischemia
Angela T.S. Wyse, Andrey V.S. Carvalho, Osmar V. Ramires Júnior, Eduardo F. Sanches, Gabriel Schirmbeck, Stéphane V. Sizonenko and Carlos A. Netto
25. Apolipoprotein E, malnutrition, and neurodegenerative risk
Gabriella C.V. Ciurleo, Camila G.M. Carvalho, Raul S. Freitas and Reinaldo B. Oriá
26. Obesity and metabolic changes in neurodegenerative diseases
Diana Sousa, Beatriz Caramelo, Christos Tsatsanis, Miguel Castelo-Branco and Paulo Matafome
27. Alzheimer’s disease: diabetes of the brain
Paula I. Moreira, Susana Cardoso and George Perry
28. The role of diet in the risk of Alzheimer’s disease
William B. Grant
29.Parkinson’s disease and nutrition
Camila Gonçalves, Jose Wagner Leonel Tavares- Junior, Andre Borges Ferreira Gomes, Jéssica Emy Komuro and Pedro Braga-Neto
Luís F. Grilo, Sandra I. Mota, Laura A. Cox, Paulo J. Oliveira and Carol Shively
2. Taste, olfactory, and food processing in the brain
Edmund Rolls
3. Maternal nutrition and epigenetic consequences for offspring cognition
Hércules R. Freitas, Ricardo A.M. Reis, Belmira L.S. Andrade-da-Costa and Isis H. Trevenzoli
4. Neurobiological programming of hedonic eating behavior
Randriely Merscher Sobreira de Lima, Patrícia Pelufo Silveira, Carla Dalmaz, Angela Marcela Jaramillo
Ospina and Rachel Krolow S.S. Bast
5. Neuroendocrine controls of appetite and satiety
Marcella Duarte Villas Mishima, Andressa Ladeira Bernardes, Luisa Lana, Łukasz Grześkowiak and Maria Do Carmo Gouveia Peluzio
6. Enteric nervous system and nutrition
Patricia Castelucci, Marcos Antônio Ferreira Caetano and Paulo Correia-de-Sá
7. Dietary modulation of gut microbiota and gut–brain axis Sofia Viana, Carolina Ferreira, Cristiana Violante, Maria Dolores Hinchado and Flávio Reis
8. Adipose tissue, adipokines, and neuroinflammation
Barbara Moura Antunes, Daniela Sayuri Inoue and Fabio Santos Lira
9. Diet, brain, and mental health
Yohannes Adama Melaku, Tefera Chane Mekonnen, Zegeye Abebe and Zumin Shi
10. Functional foods and nutraceuticals as neuroprotectors
Carolina Ferreira, Pedro Vieira, Eduardo Ortega Rincón, Flávio Reis and Sofia Viana
11. Neurosciences of sleep and nutrition
Camila Goncalves Monteiro Carvalho, Danielle Mesquita Torres, José Wagner Leonel Tavares- Júnior, Manoel Alves Sobreira-Neto and Pedro Braga-Neto
12. Food toxicants and brain health
Elena Efremenko
13. Dietary interventions and brain health
Sanika M. Joshi, Riley McCabe and Nafisa M. Jadavji
14. Understanding nutrition beyond calories and vitamins—why plants are beneficial
Megan F. Lee and Maximilian Andreas Storz
15. Omega-3 fatty acids may boost heart health in people with Parkinson’s disease
Fulvio Alexandre Scorza, Rozana Mesquita Ciconelli, Josef Finsterer, Feres Chaddad-Neto and Carla Alessandra Scorza
16. Neuroprotection and antiageing effects of caloric restriction
Roberto A. Dias, Catarina Mendes, Nuno Raimundo and Neuza Domingues
17. Neurovascular dysfunction, stroke, and age-related cognitive impairment: the benefits of the Mediterranean diet
Alexandros Zabetakis, Ioannis Zaganas, Ana Duarte, Débora Mena, Eliane Sanches and Joa ~o Malva
18. Hypercaloric diet, inflammation, and blood–brain barrier dysfunction
Filipa Isabel Baptista, Joana Margarida Gaspar, Catarina Muralha Leiria, Ana Rita Garcia, Maria Alexandra Brito and Ana Paula Silva
19. Nutrigenomics and nutrigenetics in neurological disorders
Iokasti Lazidou, Gerasimos Iordanis, Pinelopi Eleni Petrocheilou, George P. Patrinos and George Lagoumintzis
20. Neuroendocrine and nutritional disorders
Manoel Martins, Andrea Glezer, Carolina Garcia Soares Lea ~es Rech and Synara Lopes
21. Meal patterns and cognitive health in adulthood
Dora Brikou, Dimitra Dimopoulou, Nikolaos Scarmeas and Mary Yannakoulia
22. Dietary intervention, stress, and neuropsychiatric disorders
Maria Francilene Silva, Fátima de Cássia Evangelista Oliveira, Sergio Andre de Souza Junior, Pharm Tatiana Barichello and Danielle S. Macedo
23. Neurogenesis impairment in hypercholesterolemia: a potential contributor to cognitive decline and depression
Andreza Fabro de Bem, Hémelin Resende Farias, Daiane Fátima Engel, Patrícia de Souza Brocardo and Jade de Oliveira
24. Energy metabolism and mitochondrial dynamics in neurodegenerative disorders: focus on hyperhomocysteinemia and neonatal hypoxia-ischemia
Angela T.S. Wyse, Andrey V.S. Carvalho, Osmar V. Ramires Júnior, Eduardo F. Sanches, Gabriel Schirmbeck, Stéphane V. Sizonenko and Carlos A. Netto
25. Apolipoprotein E, malnutrition, and neurodegenerative risk
Gabriella C.V. Ciurleo, Camila G.M. Carvalho, Raul S. Freitas and Reinaldo B. Oriá
26. Obesity and metabolic changes in neurodegenerative diseases
Diana Sousa, Beatriz Caramelo, Christos Tsatsanis, Miguel Castelo-Branco and Paulo Matafome
27. Alzheimer’s disease: diabetes of the brain
Paula I. Moreira, Susana Cardoso and George Perry
28. The role of diet in the risk of Alzheimer’s disease
William B. Grant
29.Parkinson’s disease and nutrition
Camila Gonçalves, Jose Wagner Leonel Tavares- Junior, Andre Borges Ferreira Gomes, Jéssica Emy Komuro and Pedro Braga-Neto
- Edition: 1
- Latest edition
- Published: January 23, 2026
- Language: English
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Reinaldo B. Oria
Reinaldo Oria is a distinguished professor in the field of Histology, Pharmacology and Infectious Diseases, with a strong focus on tissue healing mechanisms and neuroscience research. He earned his Veterinary Medicine degree from the State University of Ceara in 1992 and pursued further academic pursuits that cemented his expertise. His pursuit of knowledge led him to complete a sandwich doctorate in Pharmacology from the Federal University of Ceara, which included training at the prestigious University of Virginia Center for Global Health and Infectious Diseases Division under the guidance of Dr. Richard L. Guerrant from 2002 to 2004. Dr. Oria also completed a research fellowship at the University of Virginia in 2008 and 2017. Since 2005, Oria has served as a dedicated professor in the Department of Morphology at the Faculty of Medicine of the Federal University of Ceara (UFC), where he imparts his knowledge to students through teaching Human Histology and Embryology. He’s been instrumental in advancing research through his involvement in the Image Processing Nucleus (NEMPI) and his role as the founder and coordinator of the Tissue Healing Biology Laboratory (LABICONTE) at the UFC Biomedicine Center. Oria’s research interests are wide-ranging and impactful, spanning topics like apolipoprotein E, metallopharmaceuticals, mercury intoxication, and micronutrients in various animal models and clinical studies. He has shown his commitment to academic leadership by steering the PhD Graduate Program in Medical Sciences and the Graduate Program in Morphofunctional Sciences, both at the Faculty of Medicine / UFC. Notably, his participation in the INCT Steering Committee on Brain Health underscores his influence on the national stage of neuroscience research. He is an accomplished academic who excels in teaching and research. His expertise in the field of tissue healing and neuroscience has had a significant impact on the scientific community in Brazil and beyond.
Affiliations and expertise
Federal University of Ceara, BrazilJM
Joao O. Malva
João O. Malva, PhD received his PhD in Cell Biology at the University of Coimbra 1997. He is a Principal Investigator at the Faculty of Medicine of the University of Coimbra (FMUC). He is the Director of the Project Management Unit and Science Coordinator as well as the Secretary of the Assembly at FMUC. Dr. Malva is also the Vice-Director of the Interdisciplinary Research Institute and the Science Coordinator for the consortium “Ageing@Coimbra” – European Reference Site for Active and Healthy Ageing. He is a past President of the Portuguese Society for Neuroscience (2007-2011). His research activity has been focused on Neuroscience with relevant contributions in areas such as neuroprotection, neuroinflammation and neurogenesis in brain repair. He has significant international visibility, including a nomination as full member to EDAB (European DANA Alliance for the Brain).
Affiliations and expertise
Research Coordinator, Faculty of Medicine, University of Coimbra, Portugal; Coordinator of Ageing@Coimbra, European Innovation Partnership on Active and Healthy Aging Reference Site, PortugalCN
Carlos Alexandre Netto
Carlos Alexandre Netto is Professor of Biochemistry of the Federal University of Rio Grande do Sul, UFRGS, in Brazil. Graduated in Medicine, he decided for the academic career and took his MsC and PhD Degrees on Biochemistry at the same University, and spent two years of Post Doctoral training at the Institute of Psychiatry at the University of London. His academic contribution includes more than 250 scientific papers, and supervision 80 + MsC, PhD and Post-Docs on Neuroscience, mainly on neurobiology of memory, brain ischemia and neuro-protection, neonatal hypoxia-ischemia and spinal cord lesion and stem cells. He was president of the Brazilian Society for Neurosciences and Behavior, SBNeC, and Regional Secretary of the Brazilian Society for the Advancement of Science, SBPC. Dr Netto was President of UFRGS from 2008 to 2016 and is Member of the Brazilian Academy of Sciences, ABC, since 2014.
Affiliations and expertise
Federal University of Rio Grande do Sul, UFRGS, Brazil