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Books in Life sciences

  • Protein Structure Prediction and Analysis

    • 1st Edition
    • Volume 147
    • English
    Protein Structure Prediction and Analysis, Volume 146 offers a comprehensive exploration of the methodologies, tools, and techniques utilized in the prediction and analysis of protein structures. The book delves into the fundamental principles of protein folding, modeling, and computational simulations, providing insights into the intricate process of predicting the three-dimensional structures of proteins. Sections in this new release include coverage of Current approaches for protein structure prediction and design, Protein Modelling, Prediction servers and applications in molecular modelling, Toward accurate in silico prediction of antigen binding affinities in antibody engineering, Molecular Blueprints: Guiding Drug Discovery through Protein Structure Analysis, and much more.Additional sections focus on Protein Structure Prediction Using Dynamic Speciation Evolutionary Algorithm with Problem Information Aggregation, Tau protein structure and dynamics, Tau interacts with G-protein coupled receptors (GPCRs), How to accurately predict nanobody structure: Classical physics-based simulations or deep learning approaches, Medicinal Chemistry-based Novel Therapeutics for Tauopathies in Alzheimer’s Disease, Mapping the Pathogenic Nexus: Gene Overlap and Protein Interaction Networks in Alzheimer's and Breast Cancer as a Precursor to Protein Structure Prediction and Analysis, and much more.

  • Federated Learning in Metaverse Healthcare

    Personalized Medicine and Wellness
    • 1st Edition
    • Shubham Mahajan + 1 more
    • English
    Federated Learning in Metaverse Healthcare: Personalized Medicine and Wellness explores the integration of the metaverse with healthcare, offering immersive experiences and personalized care. The book introduces federated learning, emphasizing its advantages over traditional centralized machine learning in healthcare. It provides a historical context and discusses the technological advancements that led to the emergence of metaverse healthcare. Privacy-preserving methods crucial for protecting sensitive healthcare data within federated learning environments are also examined, underscoring the importance of secure communication protocols. Other important points include the transformation of healthcare delivery through virtual environments, remote consultations, and immersive experiences.The role of telemedicine in facilitating remote diagnostics and consultations via virtual platforms, and the applications of augmented reality wearables for real-time health monitoring and wellness tracking are detailed. Additionally, the book discusses federated learning's ability to deliver personalized treatment plans tailored to individual patient needs, its role in predictive modeling for disease risks and prevention, as well as virtual health coaches offering personalized guidance for wellness management. The challenges and ethical dilemmas of metaverse healthcare and federated learning, along with potential solutions, are also considered.

  • Nanotheranostics and Precision Oncology

    • 1st Edition
    • Ramish Riaz + 4 more
    • English
    Nanotheranostics and Precision Oncology delves into the merging fields of cancer research and nanotechnology, offering a thorough review of the latest advancements in precision oncology. It begins with an exploration of cancer biology, illuminating the genetic foundations of oncogenesis alongside the cellular and molecular mechanisms driving cancer progression, metastasis, and drug resistance. This resistance remains the foremost challenge in cancer care. Across 28 chapters, the book addresses precision medicine's role in overcoming drug resistance, the importance of biomarkers, the interpretation of genetic analyses, and the shift toward personalized oncology.In addition, the book examines nanotheranostics' applications and mechanisms in cancer diagnosis and treatment, integrating them with precision oncology. It outlines the design, mechanism, and impact of nanoprecision medicine in cancer management. The final section considers the future of nanotheranostics in precision oncology and the challenges of translating these innovations from research to clinical practice. This comprehensive guide serves students, clinicians, researchers, and the pharmaceutical industry involved in nanomedicine, oncology, molecular biology, and precision medicine.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 116
    • English
    Advances in Food and Nutrition Research, Volume 116 presents the most recent developments in food science, focusing on the latest advances in understanding fundamental mechanisms and control solutions for lipid oxidation in meat. It delves into the interactions of cold plasma with food ingredient functionality, examines plant-based milk's health impacts, and critically analyzes the nutritional consequences of emerging processed foods. Additionally, the book addresses the formation and reduction of polycyclic aromatic hydrocarbons in processed foods and explores innovative technologies for meat waste valorization and the detection of bacterial pathogens using biosensors and phage biocontrol.Titles of notable chapters include Lipid Oxidation in Meat: From Fundamental Mechanisms to Latest Control Solutions, Cold Plasma interactions with Food Ingredients Functionality, Current Research on Plant-Based Milk and Impact on Health, Emerging Processed Food and its Nutritional Consequences: A Critical Analysis, and Polycyclic Aromatic Hydrocarbons in Processed Foods: Formation, Occurrence, Analysis and Reduction.

  • Biliary Tract Neoplasms

    • 1st Edition
    • Timothy M. Pawlik + 1 more
    • English
    Biliary Tract Neoplasms is a state-of-art reference of the multimodality management of bile duct cancer written by leaders in the field. As targeted therapy and clinical trials in this field are exploding, and the incidence of the disease is increasing, now is the time to address the topic in practical manner. This reference addresses surgical approaches to biliary neoplasms, targeted personalized systemic approaches to biliary neoplasms, and other treatment modalities such as radiotherapy and ablation. It is intended for scientists, researchers, clinicians, practicing surgeons, surgical oncologists, transplant surgeons as well as fellows/residents in the surgical space.The book's translational nature and impact of basic science findings that have informed targeted therapy for biliary neoplasms provide the very latest data on surgery, medical, imaging, and multi-modality care of biliary neoplasm to educate and inform care of this patient population.

  • Plant-Based Drug Discovery

    Unveiling Molecular Targets for Metabolic Conditions
    • 1st Edition
    • Mamta Bisht + 2 more
    • English
    Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.

  • Animal Models of Disease Part D

    • 1st Edition
    • Volume 197
    • English
    Animal Models of Disease, Part D, Volume 197 in the Methods in Cell Biology series presents significant advancements in understanding disease mechanisms through animal models. This volume features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

  • Less-Supervised Segmentation with CNNs

    Scenarios, Models and Optimization
    • 1st Edition
    • Jose Dolz + 2 more
    • English
    Less-Supervised Segmentation with CNNs: Scenarios, Models and Optimization reviews recent progress in deep learning for image segmentation under scenarios with limited supervision, with a focus on medical imaging. The book presents main approaches and state-of-the-art models and includes a broad array of applications in medical image segmentation, including healthcare, oncology, cardiology and neuroimaging. A key objective is to make this mathematical subject accessible to a broad engineering and computing audience by using a large number of intuitive graphical illustrations. The emphasis is on giving conceptual understanding of the methods to foster easier learning.This book is highly suitable for researchers and graduate students in computer vision, machine learning and medical imaging.

  • Handbook of Intervention Science

    From Design to Implementation
    • 1st Edition
    • Laura N.Gitlin + 1 more
    • English
    Handbook of Intervention Science: From Design to Implementation discusses multiple approaches for developing and advancing interventions at the individual, family, community, health system, and policy level. The book focuses on creating interventions suitable for diverse populations from racial, ethnical, geographical, and socioeconomical perspectives. Combining best practices with a practical approach, the book enables readers to advance their intervention research. It covers intervention design, data capture in trials, and evaluation. Decision trees help illustrate when to move forward with an implementation relative to the need for further work.

  • Phytoceuticals in Food for Health and Wellness

    Harnessing Plant Therapeutics
    • 1st Edition
    • Tanmay Sarkar + 2 more
    • English
    Phytoceuticals in Food for Health and Wellness: Harnessing Plant Therapeutics emphasizes the growing interest in the potential health benefits of phytochemicals in wellness and product development by uncovering innate bioactive compounds found in plants. Highlighting the diverse classes of phytochemicals, including flavonoids, carotenoids, polyphenols, antioxidants, and alkaloids, this book explores the sources, chemical structures, and distribution in various plants and what role they play in nutrition and disease prevention. Phytoceutical and phytochemical approaches targeting immunity, obesity, cancer, respiratory, gut, cardiovascular, and eye health, and more, will be discussed. Through traditional and modern extraction methods, Phytoceuticals in Food for Health and Wellness: Harnessing Plant Therapeutics also demonstrates how plant bioactives can be used for fortifying foods for optimal nutrition, innovating in product development, and developing the use of phytochemicals in culinary and food manufacturing applications to maximize favor and extend shelf-life.

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