Biotechnology of Terpenoid Production from Microbial Cell Factories
- 1st Edition - April 17, 2021
- Imprint: Academic Press
- Authors: Pratima Gupta, Suresh Phulara
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 1 9 9 1 7 - 6
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 3 1 7 8 - 4
Biotechnology of Terpenoid Production from Microbial Cell Factories is a unique reference to help researchers, scientists and scholars explore available strategies involved in the… Read more
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Request a sales quoteBiotechnology of Terpenoid Production from Microbial Cell Factories is a unique reference to help researchers, scientists and scholars explore available strategies involved in the production of terpenoid-based, value-added compounds from GRAS status (Generally Recognized as Safe by FDA) microbes to address the associated challenges for the industry. The book covers the most up-to-date information about microbial terpenoid production, including culture condition modulation for the improved and high-specificity production of terpenoid and their in-situ extraction. Each class of terpenoid is explained in detail, including their nutritional and pharmaceutical information and their molecular aspects.
- Provides an in-depth look at both the natural and metabolic engineering aspects of microbial terpenoid production
- Includes production strategies and existing challenges for each class of terpenoid from microbial sources
- Presents broad application opportunities of terpenoids such as food additives, pharmaceuticals and fragrances
- Includes brief chapter summaries and a glossary for each chapter to simplify technical applications
Young researchers and post-doctoral fellows who are looking into the area of flavors and pharmaceutical/nutraceutical production from microbial sources. Bio-scientists, bio-engineers from biopharmaceutical industries; biotechnology, microbiology, biochemical/chemical engineering graduate students and faculties from various higher education institutes; scientists from research institutes; and professionals from flavor and aromatic industries
- Cover Image
- Title Page
- Copyright
- Table of Contents
- Chapter 1 Introduction: Background and purpose
- Abstract
- References
- Chapter 2 Pathways for terpenoid biosynthesis
- Abstract
- 2.1 The upstream pathways
- 2.2 The isopentenyl diphosphate:dimethylallyl diphosphate isomerase
- 2.3 Downstream pathway for microbial terpenoid production
- References
- Chapter 3 Terpenoids: Types and their application
- Abstract
- 3.1 Terpenoids: types and applications
- References
- Chapter 4 Microbial hosts for the production of terpenoids
- Abstract
- 4.1 Introduction
- 4.2 Escherichia coli
- 4.3 Bacillus subtilis
- 4.4 Cyanobacteria
- 4.5 Other microbial strains
- References
- Chapter 5 Homologous and heterologous expression strategies in microbes
- Abstract
- 5.1 Engineering upstream terpenoid pathways in microbes
- 5.2 Engineering downstream terpenoid pathway enzymes in microbes
- 5.3 Engineering endogenous pathway for improved precursor and cofactor supply
- References
- Chapter 6 Culture condition modulation for the high-yield and high-specificity terpenoid production
- Abstract
- 6.1 Effect of temperature
- 6.2 Effect of medium pH
- 6.3 Effect of carbon source
- 6.4 Lignocellulosic material as a carbon source for microbial terpenoid production
- 6.5 In-situ extraction of terpenoids
- References
- Chapter 7 Production of different classes of terpenoids from microbial sources
- Abstract
- 7.1 Microbial hemiterpene production
- 7.2 Microbial monoterpene production
- 7.3 Microbial sesquiterpene production
- 7.4 Microbial diterpene production
- 7.5 Microbial carotenoid production
- References
- Chapter 8 Extraction and analysis of microbial terpenoids
- Abstract
- 8.1 Harvesting biomass
- 8.2 Cell lysis
- 8.3 Extraction of terpenoids
- 8.4 Chromatographic methods for the purification of terpenoids
- 8.5 In-situ product recovery: an integrated fermentation/downstream recovery process
- 8.6 Analysis of terpenoids
- References
- Index
- Edition: 1
- Published: April 17, 2021
- Imprint: Academic Press
- No. of pages: 224
- Language: English
- Paperback ISBN: 9780128199176
- eBook ISBN: 9780128231784
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Pratima Gupta
Dr. Pratima Gupta is an Associate Professor in Department of Biotechnology at The National Institute of Technology, Raipur, India. He is leading three sponsored research projects in microbial cells and has published articles in several journals in various disciplines including, process technology, material science, medical science, microbiology, sustainability, pharmacology, and process biochemistry, biotechnology science in a variety of journals such as: Folia Microbiologica, International Journal of Biological Macromolecules, ACS Sustainable chemistry and engineering, Journal of Applied Biomaterial and Functional Material and Journal of Applied Microbiology and Applied and Environmental Microbiology. He is currently involved in biological terpenoid research and development.
Affiliations and expertise
Associate Professor, Department of Biotechnology, The National Institute of Technology, Raipur, IndiaSP
Suresh Phulara
Dr. Suresh Phulara is an Associate Professor in Department of Biotechnology at The National Institute of Technology, Raipur, India. His main focus of research is in applied microbiology and has published many articles in several journals in various disciplines including, process technology, material science, medical science, microbiology, sustainability, pharmacology, and food science in a variety of journals such as: Folia Microbiologica, International Journal of Biological Macromolecules, ACS Sustainable chemistry and engineering, Journal of Applied Biomaterial and Functional Material and Journal of Applied Microbiology and Applied and Environmental Microbiology. He is currently involved in biological terpenoid research and development.
Affiliations and expertise
Associate Professor, Department of Biotechnology, The National Institute of Technology, Raipur, IndiaRead Biotechnology of Terpenoid Production from Microbial Cell Factories on ScienceDirect