Cellular Networks in Development
- 1st Edition, Volume 143 - April 2, 2021
- Imprint: Academic Press
- Editor: Markus Affolter
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 1 4 5 8 9 - 0
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 4 5 9 0 - 6
Current Topics in Developmental Biology, Volume 143, the latest release in this acclaimed series, highlights new advances in the field, with this new volume presenting new sectio… Read more
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Request a sales quoteCurrent Topics in Developmental Biology, Volume 143, the latest release in this acclaimed series, highlights new advances in the field, with this new volume presenting new sections on Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells, Biomechanics of Amphibian Morphogenesis, Planar cell polarity during neural tube closure, Left-right asymmetry research in Xenopus: Questions solved and new frontiers, Xenopus neural crest and its relevance to human disease, Endoderm organogenesis, From egg to embryo in marsupial frogs, Evo-devo lessons from the analysis of Xenopus genomes, Transcriptional regulation during zygotic genome activation, and much more.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in the Current Topics in Developmental Biology series
Clinicians in the fields of endocrinology, rheumatology, orthopedics, pediatrics and dentistry; basic scientists in anatomy, cell and developmental biology; students and postdoctoral fellows who would like to enter these fields and make further discoveries as well as improve the treatment of major bone-related disorders
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: Secrets of secretion—How studies of the Drosophila salivary gland have informed our understanding of the cellular networks underlying secretory organ form and function
- Abstract
- 1: Introduction
- 2: Salivary gland specification
- 3: Salivary gland fate maintenance and morphogenesis
- 4: Salivary gland functional specialization
- 5: The big push: Regulated secretion and cytoskeletal dynamics
- 6: Outlook
- Acknowledgments
- Chapter Two: Cells into tubes: Molecular and physical principles underlying lumen formation in tubular organs
- Abstract
- 1: Introduction
- 2: Types and topologies of cellular tubes
- 3: Model systems for studying lumen formation
- 4: Lumen formation through tissue folding and cell rearrangements
- 5: Mechanisms of de novo lumen formation
- 6: Roles of intracellular membrane transport in lumen formation and maturation
- 7: Shaping cells and cell behaviors—Cytoskeletal dynamics in tube formation
- 8: Pressure and tension—How mechanical forces shape cellular tubes
- 9: Conclusions and perspectives
- Funding
- Chapter Three: Pancreas morphogenesis: Branching in and then out
- Abstract
- 1: Introduction
- 2: Morphogenesis
- 3: Coupling morphogenesis to pancreas differentiation
- 4: Role of the mesenchyme, endothelial and neural networks in epithelial branching
- 5: Conclusion
- Chapter Four: Development of the metanephric kidney
- Abstract
- 1: Kidney development: An overview
- 2: The intermediate mesoderm, pronephros and nephric duct
- 3: Formation of the metanephric kidney
- 4: Branching morphogenesis
- 5: Nephron progenitor cells
- 6: Establishing the renal vasculature
- 7: Genetic and environmental perturbations to kidney development
- 8: Conclusions
- Acknowledgments
- Chapter Five: Network patterning, morphogenesis and growth in lymphatic vascular development
- Abstract
- 1: Introduction
- 2: Structure and function of lymphatics
- 3: The early cellular events in development of the lymphatic vasculature
- 4: Molecular regulation of lymphatic vascular network formation
- 5: Migration and the guidance of LECs in the embryo
- 6: Network remodeling and maturation
- 7: Network morphogenesis and cellular morphogenesis in maturing vessels
- 8: Network expansion and growth
- 9: Concluding remarks
- Acknowledgments
- Chapter Six: The control of lung branching morphogenesis
- Abstract
- 1: Introduction
- 2: Lung specification
- 3: Trachea development
- 4: Lung branching morphogenesis
- 5: Concluding remarks
- Acknowledgments
- Chapter Seven: Uncovering cellular networks in branching morphogenesis using single-cell transcriptomics
- Abstract
- 1: Introduction
- 2: scRNA-seq tools for studying morphogenesis
- 3: Cellular networks in branching morphogenesis
- 4: Using scRNA-seq to determine how physical signals dictate cell identity
- 5: Conclusions and outlook
- Chapter Eight: Building the complex architectures of vascular networks: Where to branch, where to connect and where to remodel?
- Abstract
- 1: Introduction
- 2: Where to branch: Generating new branches via sprouting
- 3: Where to connect: Formation of an interconnected network via anastomosis
- 4: Where to remodel: Optimizing flow in vascular networks via pruning
- 5: Concluding remarks and outlook
- Edition: 1
- Volume: 143
- Published: April 2, 2021
- No. of pages (Hardback): 312
- No. of pages (eBook): 312
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780128145890
- eBook ISBN: 9780128145906
MA
Markus Affolter
Markus Affolter is at University of Basel, Switzerland
Affiliations and expertise
University of Basel, SwitzerlandRead Cellular Networks in Development on ScienceDirect