SUSTAINABLE DEVELOPMENT
Innovate. Sustain. Transform.
Save up to 30% on top Physical Sciences & Engineering titles!
Cellular Networks in Development
- 1st Edition, Volume 143 - April 2, 2021
- Editor: Markus Affolter
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 1 4 5 8 9 - 0
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 4 5 9 0 - 6
Current Topics in Developmental Biology, Volume 143, the latest release in this acclaimed series, highlights new advances in the field, with this new volume presenting new sectio… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteCurrent Topics in Developmental Biology, Volume 143, the latest release in this acclaimed series, highlights new advances in the field, with this new volume presenting new sections on Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells, Biomechanics of Amphibian Morphogenesis, Planar cell polarity during neural tube closure, Left-right asymmetry research in Xenopus: Questions solved and new frontiers, Xenopus neural crest and its relevance to human disease, Endoderm organogenesis, From egg to embryo in marsupial frogs, Evo-devo lessons from the analysis of Xenopus genomes, Transcriptional regulation during zygotic genome activation, and much more.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in the Current Topics in Developmental Biology series
Clinicians in the fields of endocrinology, rheumatology, orthopedics, pediatrics and dentistry; basic scientists in anatomy, cell and developmental biology; students and postdoctoral fellows who would like to enter these fields and make further discoveries as well as improve the treatment of major bone-related disorders
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: Secrets of secretion—How studies of the Drosophila salivary gland have informed our understanding of the cellular networks underlying secretory organ form and function
- Abstract
- 1: Introduction
- 2: Salivary gland specification
- 3: Salivary gland fate maintenance and morphogenesis
- 4: Salivary gland functional specialization
- 5: The big push: Regulated secretion and cytoskeletal dynamics
- 6: Outlook
- Acknowledgments
- Chapter Two: Cells into tubes: Molecular and physical principles underlying lumen formation in tubular organs
- Abstract
- 1: Introduction
- 2: Types and topologies of cellular tubes
- 3: Model systems for studying lumen formation
- 4: Lumen formation through tissue folding and cell rearrangements
- 5: Mechanisms of de novo lumen formation
- 6: Roles of intracellular membrane transport in lumen formation and maturation
- 7: Shaping cells and cell behaviors—Cytoskeletal dynamics in tube formation
- 8: Pressure and tension—How mechanical forces shape cellular tubes
- 9: Conclusions and perspectives
- Funding
- Chapter Three: Pancreas morphogenesis: Branching in and then out
- Abstract
- 1: Introduction
- 2: Morphogenesis
- 3: Coupling morphogenesis to pancreas differentiation
- 4: Role of the mesenchyme, endothelial and neural networks in epithelial branching
- 5: Conclusion
- Chapter Four: Development of the metanephric kidney
- Abstract
- 1: Kidney development: An overview
- 2: The intermediate mesoderm, pronephros and nephric duct
- 3: Formation of the metanephric kidney
- 4: Branching morphogenesis
- 5: Nephron progenitor cells
- 6: Establishing the renal vasculature
- 7: Genetic and environmental perturbations to kidney development
- 8: Conclusions
- Acknowledgments
- Chapter Five: Network patterning, morphogenesis and growth in lymphatic vascular development
- Abstract
- 1: Introduction
- 2: Structure and function of lymphatics
- 3: The early cellular events in development of the lymphatic vasculature
- 4: Molecular regulation of lymphatic vascular network formation
- 5: Migration and the guidance of LECs in the embryo
- 6: Network remodeling and maturation
- 7: Network morphogenesis and cellular morphogenesis in maturing vessels
- 8: Network expansion and growth
- 9: Concluding remarks
- Acknowledgments
- Chapter Six: The control of lung branching morphogenesis
- Abstract
- 1: Introduction
- 2: Lung specification
- 3: Trachea development
- 4: Lung branching morphogenesis
- 5: Concluding remarks
- Acknowledgments
- Chapter Seven: Uncovering cellular networks in branching morphogenesis using single-cell transcriptomics
- Abstract
- 1: Introduction
- 2: scRNA-seq tools for studying morphogenesis
- 3: Cellular networks in branching morphogenesis
- 4: Using scRNA-seq to determine how physical signals dictate cell identity
- 5: Conclusions and outlook
- Chapter Eight: Building the complex architectures of vascular networks: Where to branch, where to connect and where to remodel?
- Abstract
- 1: Introduction
- 2: Where to branch: Generating new branches via sprouting
- 3: Where to connect: Formation of an interconnected network via anastomosis
- 4: Where to remodel: Optimizing flow in vascular networks via pruning
- 5: Concluding remarks and outlook
- No. of pages: 312
- Language: English
- Edition: 1
- Volume: 143
- Published: April 2, 2021
- Imprint: Academic Press
- Hardback ISBN: 9780128145890
- eBook ISBN: 9780128145906
MA
Markus Affolter
Markus Affolter is at University of Basel, Switzerland
Affiliations and expertise
University of Basel, SwitzerlandRead Cellular Networks in Development on ScienceDirect