Reciprocal Translation Between Pathophysiology and Practice in Health and Disease
- 1st Edition - April 1, 2021
- Authors: Peter B. Soeters, Peter W. de Leeuw
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 0 2 0 5 - 0
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 0 4 2 2 - 1
Reciprocal Translation Between Pathophysiology and Practice in Health and Disease brings a novel perspective, closing the knowledge gap between normal/abnormal physiology. Chapte… Read more
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- Provides an overview of fundamental/foundational content and then goes on to translate the information to more clinically-oriented perspectives
- Highlights the benefit of normal pathophysiological response to stress and the misunderstandings surrounding the treatment of this response
- Explains how treatment should be adapted to support the inflammatory response and how to treat its inflammatory cause
- Includes case studies and slides
PART I. PATHOPHYSIOLOGICAL MECHANISMS IN DISEASE1. Reciprocal translation between pathophysiology and practice in health and disease2. General principles of the repair mechanism3. Cardiovascular responses to injury4. Insulin resistance as an adaptive mechanism5. Hypercholesterolemia, harm or benefit?6. Macronutrient metabolism in starvation and stress7. The role of ectopic adipose tissue: benefit or deleterious overflow? 8. The gut/liver axis, inflammation and the pathogenesis of metabolic syndrome9. Harm and benefit of the inflammatory response
PART II. CLINICAL MANIFESTATIONS OF ADAPTIVE PATHOPHYSIOLOGY 10. The beneficial role of inflammation and metabolic cycling (Warburg revisited)11. From hepatic encephalopathy to the quality of food protein and pro-tein requirements: a serendipitous journey 12. The underlying metabolism of hypoalbuminemia and its clinical effects13. Cardiovascular stress syndromes14. The benefit of moderate hyperglycemia and hyperlactatemia in critical illness or synthesis of biomass15. Anemia as an adaptive phenomenon16. Vitamin D in health and disease
PART III. IMPLICATIONS FOR TREATMENT 17. Decreases of plasma solutes in health and disease: deficiency or resulting from changing binding proteins and distribution volume?18. Comparable metabolism in pregnancy and cancer: a universal role of the Warburg effect19. Nutritional assessment and the role of pre-existent inflammation with a bearing on COVID-1920. The harm afflicted by NSAIDs, statins and oral antidiabetics by blocking adaptive inflammatory metabolism21. Benefit and concern of ketogenic and vegan diets: a revisit to pathophysiology
PART IV. MECHANISMS PROVIDING INSIGHT IN A FEW ENIGMATIC SYNDROMES22. Pathophysiology in practice: How to manage gastrointestinal surgery in acute and elective disease conditions23. The pathophysiology underlying the obesity and plasma cholesterol paradoxes24. The final conclusion: dogma, bias and big data
- No. of pages: 334
- Language: English
- Edition: 1
- Published: April 1, 2021
- Imprint: Academic Press
- Paperback ISBN: 9780128202050
- eBook ISBN: 9780128204221
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Peter B. Soeters
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