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Elsevier

Books in Neuroscience general

Bridging multiple disciplines, this portfolio provides a comprehensive overview of nervous system structure, function, and disorders. Supporting researchers, students, and clinicians, it features foundational theories, interdisciplinary research, and emerging trends that advance understanding of brain and nervous system health.

  • Genome Editing for Neurodegenerative Diseases

    From Concept to Clinical Trials
    • 1st Edition
    • Sandeep Kumar Singh + 3 more
    • English
    Genome Editing for Neurodegenerative Diseases: From Concept to Clinical Trials examines recent advances in neurodegenerative disease research and clinical challenges in practical applications. With an emphasis on genome editing tools such as ZFNs, TALENSs and CRISPR-Cas, this book sheds light on the possibilities to counteract genetic and neurodegenerative diseases. It will be of interest to researchers in neuroscience and biopharmaceuticals, as well as clinicians specializing in neurodegenerative diseases.

  • Radiomics and Radiogenomics in Neuro-Oncology

    An Artificial Intelligence Paradigm – Volume 2: Genetics and Clinical Applications
    • 1st Edition
    • Sanjay Saxena + 1 more
    • English
    Radiomics and Radiogenomics in Neuro-Oncology: An Artificial Intelligence Paradigm—Volume 2: Genetics and Clinical Applications provides readers with a broad and detailed framework for radiomics and radiogenomics (R-n-R) approaches with AI in neuro-oncology. It delves into the study of cancer biology and genomics, presenting methods and techniques for analyzing these elements. The book also highlights current solutions that R-n-R can offer for personalized patient treatments, as well as discusses the limitations and future prospects of AI technologies.Volume 1: Radiogenomics Flow Using Artificial Intelligence covers the genomics and molecular study of brain cancer, medical imaging modalities and their analysis in neuro-oncology, and the development of prognostic and predictive models using radiomics.Volume 2: Genetics and Clinical Applications extends the discussion to imaging signatures that correlate with molecular characteristics of brain cancer, clinical applications of R-n-R in neuro-oncology, and the use of Machine Learning and Deep Learning approaches for R-n-R in neuro-oncology.

  • Targeted Therapy for the Central Nervous System

    Formulation, Clinical Challenges, and Regulatory Strategies
    • 1st Edition
    • Viral Patel + 3 more
    • English
    Targeted Therapy for the Central Nervous System: Formulation, Clinical Challenges, and Regulatory Strategies presents research on various delivery methods of drugs to the central nervous system and brain. This volume examines targeted therapies for neurodegenerative disorders and succinctly outlines the future of drug delivery systems, highlighting significant advancements specifically relating to central nervous system delivery. This book will be of great interest to researchers working in the field of neuroscience and pharmacology as well as clinicians (pharmacists, radiologists, psychiatrists).

  • Medical Image and Signal Analysis in Brain Research

    • 1st Edition
    • Volume 290
    • English
    Progress in Brain Research, Volume 290 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this release include Image Analysis for Spinocerebellar Ataxia Type 3, Brain structural network modular and connectivity alterations in subtype of patients with migraine, Brain Functional Networks and Structures that Categorize Type 2 Bipolar Disorder and Major Depression, Reinforcement Learning Classification in fNIRS Signal of Olfactory Stimulated, The method of brain-computer interface using the forehead instead of the visual area to receive SSVEP signals and signal processing, and more.Additional chapters cover The relationship between flash-induced SSVEP in DELTA frequency band and sleep, Enhancing Facial Feature De-Identification in Multi-Frame Brain Images: A Generative Adversarial Network Approach, Comparative Analysis of MRI Markers in Heat and Mechanical Pain Sensitivity, and Analysis of the Difference Between Alzheimer’s Disease, Mild Cognitive Impairment and Normal People by Using Fractal Dimensions and Small-World Network.

  • Handbook of Neural Engineering

    A Modern Approach
    • 1st Edition
    • Stephanie Willerth
    • English
    Handbook of Neural Engineering: A Modern Approach provides a comprehensive overview of the field from biology to recent technological advances through an interdisciplinary lens. The book is divided into three sections: 1) Biological Considerations for Neural Engineering, 2) Neural Engineering Strategies, and 3) Emerging Technologies for Neural Engineering. It provides the first comprehensive text that addresses this combination of subjects. Neurodegenerative diseases, including Alzheimer’s, Parkinson’s and Multiple Sclerosis, represent an enormous healthcare burden, and many of these diseases lack true cures, making it imperative to study the biological systems that become disordered to understand potential treatment options.This book covers the basic neurobiology and physiology, common neural engineering strategies, and emerging technologies in this field. It is designed to support an upper year/graduate elective course in neural engineering, and will provide a foundational overview of the field for interdisciplinary researchers, clinicians, engineers, and industry professionals. The handbook provides readers with a strong base in both biological and engineering principles along with the concepts necessary to implement solutions using Neural Engineering.

  • From Anatomy to Function of the Central Nervous System

    Clinical and Neurosurgical Applications
    • 1st Edition
    • Brandon Matteo Ascenzi
    • English
    From Anatomy to Function of the Central Nervous System: Clinical and Neurosurgical Applications features neuroradiologic images that represent today, one of the most effective resources able to detect the anatomy of the nerve structures. Simultaneously featuring neuroimages, readers can study the functional aspects of the entire central nervous system with detailed captions that describe in detail how to use and interpret them. This book includes images of the brain dissected with the Klingler’s method and white matter fiber dissection. By integrating the anatomo-functional description with the synaptic organization of the CNS, this reference is useful for anyone who wants to understand how the activity of a nerve structure arises, describing its microstructure, neurotransmitter phenotype, and neural activity. It also features descriptions of pathologic conditions which result from neuroanatomical and/or neurofunctional alterations and includes neurosurgical aspects.

  • Neuroscience of Coffee Part A

    • 1st Edition
    • Volume 288
    • English
    The Neuroscience of Coffee is a pioneering volume that delves into the intricate relationship between one of the world's most beloved beverages and the human brain. Offering a comprehensive exploration of the biochemical and physiological mechanisms underlying coffee's impact on the nervous system, this groundbreaking book transcends traditional coffee literature by focusing specifically on the neurological aspects. From deciphering the molecular intricacies of caffeine to examining the complex interactions within the nervous system, the volume provides an unprecedented insight into how coffee influences brain function, mental health, and neurodegenerative diseases. It addresses the growing interest in understanding everyday dietary choices and their neurological implications, filling a crucial gap in accessible yet detailed resources. This book not only contributes to the evolving field of neuroscience but also serves as a valuable guide for professionals, students, and informed laypersons seeking a deeper understanding of coffee's effects on brain health and overall well-being.

  • Fundamentals of Health Neuroscience

    • 1st Edition
    • Yi-Yuan Tang + 1 more
    • English
    Health Neuroscience is a new interdisciplinary field encompassing research from cognitive, affective, and social neuroscience, health psychology, physical and mental health, and science of behavior change. This new field addresses the longstanding gap among neuroscience, health, and behavior change within the context of health promotion.Fundamenta... of Health Neuroscience explores key topics and research, including basic principles, psychological and neural processes, brain and body interactions, and gene x brain x environment interactions. This book also covers brain-based precision prevention and intervention strategies for health decisions and promotion across the lifespan. Chapters integrate the latest research findings and explores several key topics, such as: How does the brain serve both as a predictor and an outcome of health? How can people improve self-control and achieve physical and mental health effectively? What does brain plasticity and resilience tell us about optimal learning, performance, and development throughout our life? How is the sense of meaning in life affected by dopamine and reward systems in the brain?

  • The Neurophysiology of Silence (C): Creativity, Aesthetic Experience and Time

    • 1st Edition
    • Volume 287
    • English
    Neurophysiology of Silence: Consciousness and Self Awareness, Volume 284 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Cannabidiol in Neurology and Psychiatry

    • 1st Edition
    • Volume 177
    • English
    Cannabidiol in Neurology and Psychiatry, Volume 177 in the International Review in Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topic such as Historical perspective on the therapeutic potential of cannabidiol, Cannabidiol: pharmacodynamics pharmacokinetic, Cannabidiol and Alzheimer’s disease, Cannabidiol on anxiety disorders, Cannabidiol on psychosis, Cannabidiol on autism spectrum disorders, Cannabidiol in Epilepsy, Cannabidiol in Ischemia/stroke, Cannabidiol in Depression, Cannabidiol and Abuse of drugs, and much more.Additional chapters cover Cannabidiol in fear response and PTSD, Cannabidiol and Pain. and Cannabidiol and Parkinson’s disease.

  • Executive Brain Vitality

    Achieving Optimal Brain Health and Maintenance: A Practical Manual
    • 1st Edition
    • Michael Hoffmann
    • English
    Executive Brain Vitality: Achieving Optimal Brain Health and Maintenance presents research on the effect of brain exercise as a preventative measure for neurodegenerative diseases and other conditions. This volume examines the neurological impact of such exercises from research to clinical application, offering up-to-date research and practical steps. The current book will be of interest to researchers in neurodegeneration and chronic disease as well as practitioners and clinicians interested in the preventative approach in medicine.

  • Human Neuroanatomy

    • 1st Edition
    • Reha Erzurumlu + 2 more
    • English
    Human Neuroanatomy is a unique resource that presents the neuroanatomy of the central and peripheral nervous systems. This atlas-style reference features human brain sections with radiological correlations and original illustrations accompanying macroscopic and microscopic photographs. Chapters include a large number of illustrations in the form of photographs, Illustrations, and MR imaging, including a human brain atlas. Boxes within each chapter contain clinical information, with tables of topic summaries. Presented along with clinical approaches and analyses, this is a reference for all neuroscientists, neurosurgeons, neurologists, medical students, and all students of neuroscience.

  • Enhancement of Brain Functions Prompted by Physical Activity Vol 2

    • 1st Edition
    • Volume 286
    • English
    Enhancement of Brain Functions Prompted by Physical Activity, Volume Two, Volume 286 in the Progress in Brain Research series, highlights new advances, with this updated volume presenting chapters on a variety of timely topics, including Predicting sports performance of elite female soccer players through smart wearable measurement platform, Physical activity and verbal memory performance: mediating effects of resting-state brain activity, Associations between physical activity, body composition, and cognitive performance among female office workers, Grip strength, working memory, and emotion perception in middle aged males, Association of aerobic fitness and grip strength with cognitive and academic performance in Arab children, and much more.

  • Motor Neurone Disease

    • 1st Edition
    • Volume 176
    • English
    Motor Neurone Disease, Volume 176 in the International Review in Neurobiology serial highlights new advances, with this new volume presenting interesting chapters written by an international board of authors. Updates include chapters on Clinical features, differential diagnosis and pathology, Recent advances in genetics of familial and sporadic ALS, Non-coding genome contribution to ALS, Contribution of neurophysiology to the diagnosis and monitoring ALS, Advances in symptom management and monitoring disease progression, Use of biomarkers in clinical trials and future developments that will help identify new biomarkers, Application of systems biology to identify therapeutic targets, and much more.Additional sections cover Evidence of mitochondrial dysfunction (in ALS) and how to measure it in model systems, Current neuroprotective therapies and future prospects, The role of glial cells in ALS, Dysregulation of RNA biology in ALS, New developments in pre-clinical models of ALS to guide translation.

  • Brains and Machines: Towards a unified Ethics of AI and Neuroscience

    • 1st Edition
    • Volume 7
    • English
    Brains and Machines: Towards a unified Ethics of AI and Neuroscience provides a comprehensive overview of concepts and ethical issues at the intersection of two emerging technological trends in the 21st century: AI and neurotechnology. In line with recent advances across both fields, debates about philosophical, ethical, regulatory and social issues raised by neuroscience and AI have considerably expanded in the past decade. Yet, despite many intersections and fruitful interactions between the two scientific domains, ethical debates about neuroscience and AI have mostly moved in parallel. This volume assembles voices from various disciplines to provide a more unified view and offer novel perspectives on two complementary lines of discourse. The volume provides scientific background by outlining the state of the art of applying AI in the field of neuroscience and discussing instances where findings and debates from neuroscience provide cues and inspiration to the study of AI. Based on this background, the book then addresses conceptual frameworks, identifies ethical challenges at the intersection of neuroscience and AI, and highlights challenges and opportunities of finding common ground in interdisciplinary settings.

  • Cranial Surgery - Part 2

    • 1st Edition
    • Volume 285
    • English
    This is a study of the evolution of the principles and techniques of cranial surgery from Hippocrates to the nineteenth century. The methods of conveying information by text and image are considered.

  • Neurogenetics for the Practitioner

    • 1st Edition
    • Gregory M. Pastores
    • English
    Neurogenetics for the Practitioner provides clinicians with a navigation tool to help diagnose and treat patients with neurological disorders using neurogenetics. Sections introduce the reader to an overview of genetic principles, including practical applications in relation to diagnosis and current limitations. Additional chapters highlight how to workup patients presenting with certain features, including cerebral palsy/intellectual disability, congenital muscular dystrophy, cognitive decline/dementia, peripheral neuropathy, and paroxysmal disorder. The final section explores therapeutic strategies based on genetic interventions and genetic counselling options. This internationally contributed book will become the essential reference guide for neurologists.

  • Cranial Surgery - Part 1

    • 1st Edition
    • Volume 284
    • Jeremy Christopher Ganz
    • English
    This is a study of the evolution of the principles and techniques of cranial surgery from Hippocrates to the nineteenth century. The methods of conveying information by text and image are considered.

  • Radiomics and Radiogenomics in Neuro-Oncology

    An Artificial Intelligence Paradigm - Volume 1: Radiogenomics Flow Using Artificial Intelligence
    • 1st Edition
    • Sanjay Saxena + 1 more
    • English
    Radiomics and Radiogenomics in Neuro-Oncology: An Artificial Intelligence Paradigm, Volume One: Radiogenomics Flow Using Artificial Intelligence broadly encompasses the study of life-threatening brain and spinal cord malignancies, including primary lesions and those metastasizing to the central nervous system. Radiomics is an approach to medical imaging used to extract many quantitative imaging features using different data characterization algorithms, while radiogenomics, which has recently emerged as a novel mechanism in neuro-oncology research, focuses on the relationship of imaging phenotype and genetics of cancer. Sections in this book discuss several AI approaches that have been applied to conventional and advanced medical imaging data. These AI-based R-n-R tools have the potential to stratify patients into more precise initial diagnostic and therapeutic pathways and permit better dynamic treatment monitoring in this period of personalized medicine. While extremely promising, the clinical acceptance of R-n-R methods and approaches will primarily hinge on their resilience to non-standardization across imaging protocols and their capability to show reproducibility.

  • The neurobiology of Alcohol Use Disorder

    Neuronal mechanisms, current treatments and novel developments
    • 1st Edition
    • Volume 175
    • English
    The Mechanisms Behind Developing Dependence, Sub-groups, and Novel Approaches to Treatment, Volume 174 in the Neurobiology of Alcohol Abuse series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Substitution therapy in alcohol treatment, with a focus on mechanisms and possibilities, Designing and analyzing studies on treatments for alcohol dependence, The harm reduction approach for treatment of alcohol dependence, Current treatments for alcohol dependence, with a suggested focus on mechanisms and possibilities, Metabolomics in relation to alcohol dependence with focus on possibilities for precision medicine, and Repurposing drugs for treatment of alcohol dependence.

  • Enhancement of Brain Functions Prompted by Physical Activity Vol 1

    • 1st Edition
    • Volume 283
    • English
    The goal for this special edition of Progress in Brain Research extends beyond merely probing the yet-to-be-uncovered links between physical exercise and cognitive improvement. We aim to advance our knowledge, pushing the envelope of what is currently understood. We are particularly focused on how purposefully structured physical activities, carefully chosen participant groups, and specific cognitive areas can optimize the cognitive and mental health benefits derived from physical exercise. The inaugural volume of this series introduces 3 review articles and 7 original pieces of research, encompassing both behavioral experiments and neuroimaging studies. Our focus is on experimental research that sheds light on the immediate and long-term impact of physical exercise on cognition as well as expert opinions and systematic reviews that compile current findings and suggest avenues for upcoming research.

  • Translational Approaches to Unravelling Non-Motor Symptoms of Parkinson’s disease

    • 1st Edition
    • Volume 174
    • English
    Translational Approaches to Non-Motor Symptoms of Neurodegenerative Diseases, Volume 173 in the International Review on Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters on topics such as A general clinical overview of the non-motor symptoms, Stress/fatigue/cogni... decline Sleep/autonomic failure, A general clinical overview of the non-motor symptoms – psychiatric symptoms, Psychosis, Cognitive Decline, Non-clinical Aspect of non-motor symptoms: Animal Models, Assessment and treatment of cognitive decline in rodent and primate models, Pain in PD models, Affective disorders in PD models, Sleep and circadian dysregulation and EEG disruption in rodent models, and much more.

  • The Neuroscience of Bach’s Music

    Perception, Action, and Cognition Effects on the Brain
    • 1st Edition
    • Eric Altschuler
    • English
    The Neuroscience of Bach’s Music: Perception, Action, and Cognition Effects on the Brain is a comprehensive study of Johann Sebastian Bach’s music through the lens of neuroscience, examining neuroscience using Bach’s music as a tool. This book synthesizes cognitive neuroscience, music theory, and musicology to provide insights into human cognition and perception. It also explores how a neuroscience perspective can improve listening and performing experiences for Bach’s music. Written by a physician-neuroscien... recognized for scholarly articles on Bach’s music, this book uses specific examples to explore neuroscience across Bach’s compositions.The book is structured to discuss the brain’s action, perception, and cognition as connected to specific Bach concertos, tones, notes, and performances. Two guest contributors provide insight into exact mathematical, or topologic, and music theoretic aspects of Bach’s music with implications for cognitive neuroscience.

  • Handbook of Digital Technologies in Movement Disorders

    • 1st Edition
    • Roongroj Bhidayasiri + 1 more
    • English
    Handbook of Digital Technologies in Movement Disorders aims to unite these factors to provide a comprehensive guide to patient focused treatments for movement disorders. Sections cover an introduction to digital technologies, concepts, and terminologies, review various perspectives on technology in movement disorders, including patient and medical professionals, and present technologies used in detecting, measuring progression, and determining response to treatments. Additional chapters review the technology used in various treatments of movement disorders, including assistive and robotic technologies. Finally, the last section examines the challenges with technology, including privacy and other ethical issues. Over the past few years, there have been fundamental changes in the diagnosing and treating patients with chronic diseases, significantly affecting management of neurological movement disorders. In addition, the health and fitness sector developed several devices to better classify, track, and potentially treat chronic diseases. Both handling and interpreting these large datasets has been revolutionized, by machine and deep learning approaches, leading to new and more effective therapies, resulting in longer survival rates.

  • The Rhesus Monkey Brain in Stereotaxic Coordinates

    • 4th Edition
    • George Paxinos + 2 more
    • English
    The Rhesus Monkey Brain in Stereotaxic Coordinates is the most comprehensive and accurate atlas of the monkey brain. The fourth edition of this classic book is a complete revision featuring many improvements and upgrades. Constructed by the established leaders in neuroanatomical atlas development, the new edition will continue to be the indispensable resource for all scientists working on the primate nervous system.

  • Brain and Maths in Ibero-America

    • 1st Edition
    • Volume 282
    • English
    Brain and Maths in Ibero-America, Volume 282 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Fragile X and Related Autism Spectrum Disorders

    • 1st Edition
    • Volume 173
    • English
    Fragile X and Related Autism Spectrum Disorders, Volume 172 in the International Review on Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on The dopamine hypothesis of Autism Spectrum Disorder: a comprehensive analysis of the evidence, A Review of the Use of Psychotropic Medication to Address Challenging Behavior in Neurodevelopmental Disorders, Lipid metabolism alterations in fragile X syndrome and other neurodevelopmental disorders, Genesis, modelling and methodological remedies to autism heterogeneity, Toward an Understanding of the Role of the Exposome on Fragile X Phenotypes, Glial-mediated dysregulation of neurodevelopment in Fragile X Syndrome, and more.

  • Progress in Motor Control

    From Neuroscience to Patient Outcomes
    • 1st Edition
    • Mindy F. Levin + 3 more
    • English
    Progress in Motor Control: From Neuroscience to Patient Outcomes updates the state-of-the-art of knowledge among scientists on basic and applied research on control of movements of biological systems through a clinical perspective. Motor control is a scientific area characterized by multidisciplinary approaches. This book promotes the application of this area into clinical practice. Chapters focus on topics in the field of motor control, including neural control of goal-oriented action, theories on rules of interaction during motor learning, and action coordination up to human and machine interaction.Edited by experts in the field, this book translates current theoretical outcomes into neuroscience and therapeutic solutions.

  • Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-Morbidity Factors Part B

    • 1st Edition
    • Volume 172
    • English
    Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors, Part B, Volume 172 in the International Review of Neurobiology series, includes chapters on Spinal cord injury induced exacerbation of Alzheimer's disease pathophysiology in the cord is reduced by topical application of nanowired cerebrolysin and antibodies to tumor necrosis factor alpha, Nanodelivery of histamine H3 receptor inverse agonist BF-2549 with clobenpropit a H3 receptor antagonist and H4 receptor agonist induced neuroprotection in spinal cord injury is potentiated by antioxidant compound H-290/51, and Neuromodulation and quality of life for patient with spasticity after spinal cord injury, and more.Other sections cover Efficacy of invasive and non-invasive methods for the treatment of Parkinson´s disease: nanodelivery and enriched environment, Co-administration of DL-3-n-butylphthalid... and neprilysin is neuroprotective in Alzheimer disease associated with brain injury, Nicotine Neurotoxicity Exacerbation following Engineered Ag and Cu (50-60 nm) nanoparticles intoxication, and Neuroprotection with nanowired delivery of antioxidant compound H-290/51 together with serotonin 5-HT3 receptor antagonist ondansetron.

  • Treatment-Resistant Depression Part B

    • 1st Edition
    • Volume 281
    • English
    Treatment-Resistant Depression, Part B, Volume 281 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on highly relevant topics such as Treatment Resistant Depression in Children and Adolescents, Treatment Resistant Depression in Elderly, Brain Stimulation for Treatment Resistant Depression, Electroconvulsive Therapy for Treatment Resistant Depression, Psychological aspects and Psychotherapy for Treatment Resistant Depression, Psychiatric Rehabilitation and Cognitive Deficit for Treatment-Resistant Depression, Insomnia and Treatment Resistant Depression, and Tinnitus and Treatment Resistant Depression.

  • Adenosine A2A Receptor Antagonists

    • 1st Edition
    • Volume 170
    • English
    Adenosine A2A Receptor Antagonists, Volume 170 in the International Review of Neurobiology series highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including A2A Adenosine Receptor Agonists, Antagonists, Inverse Agonists and Partial Agonist, Chemistry – agonists, antagonists, partial agonists, inverse agonists, Functional roles of adenosine receptors – biochemistry and neuronal plasticity, A2A and Depression, A2AR and glial function, The adenosine A2A receptor in the basal ganglia: expression in health and disease, heteromerization, functional selectivity and signaling, How and why A2a receptor become to be a therapeutic target in Parkinson’s disease therapy, and much more.

  • Neurophysiology of Silence Part B: Theory and Review

    • 1st Edition
    • Volume 280
    • English
    Progress in Brain Research serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors

  • Neuroethics and Neurodevelopment

    • 1st Edition
    • Volume 6
    • English
    This volume focuses on topics at the intersection between neuroethics and neurodevelopment, and brings together the perspectives of experts in both clinical assessment and intervention, and researchers in child psychology, neurosciences, medicine, health policy, law, and social work. The goal is to review emerging issues related to the ethical ramifications of how variation in human neurodevelopment is described, and the effects of these descriptions on those with lived experience, clinical and intervention services, and health and social policy. Related topics are also explored including the effect of the Covid-19 pandemic, the ethics of invasive neurotechnology interventions, biomarkers, machine learning, precision medicine.

  • Game-Based Learning in Education and Health Part B

    • 1st Edition
    • Volume 279
    • English
    Game-Based Learning in Education and Health, Part B, Volume 279 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on highly relevant topics including Evaluating the validity of game-based assessments measuring cognitive function among children and adolescents: A systematic review and meta-analysis, Children grow upwards, and so does the number line: Evidence from a directional number line paradigm, and Tasting inhibition: A proof-of-concept study of the food stop-signal game.

  • Dystonia

    • 1st Edition
    • Volume 169
    • English
    Dystonia, Volume 169, the latest release in the International Review of Neurobiology serial, highlights new advances in the field with this new volume presenting interesting chapters on topics including Clinical Features and the Science of Classification, What Can Epidemiological Studies Tell us About the Neurobiology of Dystonia, Dystonia Genes and Their Biological Pathways, Functional Anatomy of Dystonia, Physiology of Dystonia: Human Studies, Physiology of Dystonia: Animal Studies, Experimental Pharmacology: Targeting Neurotransmitters, Experimental Pharmacology: Targeting Metabolic Pathways, Adult-Onset Focal Dystonias: One Biology or Many?, Early-Onset Inherited vs Late-Onset Idiopathic Dystonias: Same or Different Biological Mechanisms?, and much more.

  • Treatment-Resistant Depression

    • 1st Edition
    • Volume 278
    • English
    Progress in Brain Research, Volume 278, the latest release in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters on Treatment Resistant Depression overview in Adult, Treatment Resistant Depression in Children and Adolescents, Treatment Resistant Depression in Elderly, Headache and Treatment Resistant Depression, Insomnia and Treatment Resistant Depression, Tinnitus and Treatment Resistant Depression, Genetics of Antidepressant Response and Treatment Resistant Depression, Neuroinflammation via Gut-Microbiota-Brain Axis in Treatment Resistant Depression, Molecular Imaging findings for Treatment Resistant Depression, and more. Additional sections cover Functional MRI markers for Treatment Resistant Depression: Insights and Current Challenges, Medication Strategies for Treatment Resistant Depression, Brain Stimulation for Treatment Resistant Depression, Electroconvulsive Therapy for Treatment Resistant Depression, Next Generation Antidepressants with Novel Mechanisms for Treatment Resistant Depression, Psychological aspects and Psychotherapy for Treatment Resistant Depression, and Psychiatric Rehabilitation for Treatment Resistant Depression.

  • Nonlinear Dynamics of Parkinson’s Disease and the Basal Ganglia-Thalamic-Cortical System

    • 1st Edition
    • Erwin B. Montgomery Jr. + 1 more
    • English
    Nonlinear Dynamics of Parkinson’s Disease and the Basal Ganglia-Thalamic-Cor... System examines current research regarding the operations of the basal ganglia-thalamic-cor... system that causes neurological disorders like Parkinson’s disease. While there have been remarkable advances in the understanding of the anatomy, physiology and chemistry of these systems, there remains a significant degree of inconsistency and incompleteness between facts and advancements. This book introduces the novel concepts of nonlinear complex systems and their connection to Parkinsonism as well as hyperkinetic disorders. The actual mechanisms underlying the motor disorders of Parkinson’s disease at the level of the lower motor neuron are also discussed.

  • Neurophysiology of Silence Part A: Empirical Studies

    • 1st Edition
    • Volume 277
    • English
    Neurophysiology of Silence, Volume 277 in the Progress in Brain Research series, highlights new advances in the field, including chapters on Mindfulness, mind wandering and creativity, The cloud of unknowing: Cognitive dedifferentiation in whole-body perceptual deprivation, Embodying abstract concepts: the connection between meditation, empathy and introception, Measures of music-like experience emergent in a sonic ganzfeld: an example of perceptual structuring on the edge of silence, Doing out of silence: The effects of visual art on verbal creativity, Cessation experiences during meditation, The psychophysiology of covert behavior during goal directed behavior, and much more.

  • Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders

    • 1st Edition
    • Heba Mohamed Mansour + 2 more
    • English
    Overexpression of receptor tyrosine kinases (RTKs) has been implicated in cancer. Increasing evidence suggests that dysregulation of RTKs is reported in many neurodegenerative and psychiatric disorders. Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders provides a fundamental, pragmatic map of RTKs structure, activation, functions, mechanism of action, gene regulation, and signaling pathways in developing central nervous system (CNS), adult normal CNS, neurodegenerative and psychiatric disorders. Additionally, the structure, function, activation, and therapeutic potential of many growth factors have been covered. Here, international experts in the field offer a comprehensive discussion of results of pre-clinical and clinical studies of repositioning of anti-cancer receptor tyrosine kinase inhibitors (RTKIs) and other promising protein kinase inhibitors in various neurodegenerative disorders including, Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis, and psychiatric disorders including, anxiety, depression, alcohol use disorder, and schizophrenia. In addition, the book discusses the obstacles and opportunities for the potential repositioning of kinase inhibitors in neurodegenerative and psychiatric disorders.

  • Neurobiology and Physiology of the Endocannabinoid System

    • 1st Edition
    • Vinood B. Patel + 2 more
    • English
    Neurobiology and Physiology of the Endocannabinoid System offers readers a comprehensive reference on the neurobiology of this system and the use of cannabimimetic compounds to induce neurological changes and confer symptom relief. With sections on both natural and synthetic compounds, the book's broad coverage allows readers to learn about their use with multiple conditions, as well as the working biology of the endocannabinoid system, its receptors and its ligands. This volume provides a platform for research on the effects of this system and its modulation in brain function and neurological dysfunction.

  • Medicinal Usage of Cannabis and Cannabinoids

    • 1st Edition
    • Victor R. Preedy + 2 more
    • English
    There is a growing body of data supporting the usage of cannabis and cannabis-related products in alleviating or preventing symptoms in different diseases and conditions. Medicinal Usage of Cannabis and Cannabinoids offers readers a comprehensive reference on the medical usage and symptom relief provided by these compounds in a variety of disorders. With coverage of neurological diseases like Alzheimer’s and Parkinson’s, and a wide range of other afflictions including depression, anxiety, nausea, and cancer, this broad coverage allows readers to learn about symptom control but also physiological, psychological, and pharmacological effects of these compounds. Unique case reports are provided as well. This volume provides a platform for research on the use of these compounds in improving patient care, brain function, and neurological dysfunction.

  • Clinical Neuroepidemiology of Acute and Chronic Disorders

    • 1st Edition
    • Jahangir Moini + 2 more
    • English
    Clinical Neuroepidemiology of Acute and Chronic Disorders explores the epidemiology of disorders that affect the nervous system, providing comprehensive discussions on incidence, prevalence, and more. With thorough coverage of a variety of disorders, chapters detail etiology, risk factors, pathophysiology, clinical manifestations, diagnosis, global incidence and prevalence, age-specific incidence, global mortality, prevention, treatment and prognosis for each disorder. Chapters uniquely discuss the effects of the COVID-19 coronavirus upon the nervous system and in relation to several diseases, including new discoveries and treatments for Alzheimer’s disease and migraine headaches. Real-world case studies with critical thinking questions and "Focus On" boxes highlight important information.

  • Game-Based Learning in Education and Health - Part A

    • 1st Edition
    • Volume 276
    • English
    Game-Based Learning in Education and Health, Volume 276 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Math computerized games in the classroom: a Number Line Training in Primary School Children, Digital games for learning basic arithmetic at home, Game-Based Assessment of Cognitive Function among Children and Adolescents: A Systematic Review and Meta-Analysis, Different aspects of fraction understanding are associated selectively with performance on a fraction learning game, and more.

  • From Fossils to Mind

    • 1st Edition
    • Volume 275
    • English
    From Fossils to Mind, Volume 275 in the Progress in Brain Research series, presents chapters on a variety of interesting topics, including What could our premammalian ancestors hear, see, smell, and touch? A review of ten years of research about cynodont paleoneurology, Endocasts of ornithopod dinosaurs: anatomy and comparison, Adaptationism and Structuralism in Brain Evolution Research, Genomic approaches for tracing the evolution of brain ageing and neurodegenerative diseases, Investigating the Coevolution of Language and Tools in the Brain: An ALE Meta-analysis of Neural Activation During Syntactic Processing and Tool Use, and more.

  • Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders

    • 1st Edition
    • Volume 168
    • English
    Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders, Volume 168 in the International Review of Neurobiology series, highlights advances in the field, with this new volume presenting interesting chapters on topics such as mGlu receptors in Parkinson’s disease, Metabotropic glutamate receptors in estradiol-mediated motivated behaviors in females, mGlu regulation of sleep, Implications for sleep disruptions in psychiatric disorders, Mechanisms of mGlu receptor trafficking; alterations by methamphetamine, Group I mGlu and cocaine seeking, The role of mGlu receptors in fear and anxiety, Regulation of Alcohol Consumption, Reward, Dependence, and Perception by Metabotropic Glutamate Receptor Signaling, and mGlu5 as a biomarker for psychiatric disorders.

  • Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery

    • 1st Edition
    • Elena L. Paley
    • English
    Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery focuses on the emerging hypothesis of a dysfunctional microbiome metabolome vagus nerve brain circuit in Alzheimer’s disease and associated diseases and medical conditions, including dementia, aging, COVID-19, autoimmune conditions, and inflammatory skin condition rosacea, which may increase the risk of other conditions. This book also discusses the vagus nerve-related conditions, including Arnold’s reflex, laryngopharyngeal reflux, duodenogastric reflux, gastroesophageal reflux, and related pulmonary diseases. The subjects covered in the book also address an important question of which one is more important for human health and intellectual abilities: the human genome or the human microbiome? The conceptual model of food and gut microbial tryptamine vagus nerve circuit is also presented in this book.

  • Handbook of Cognitive Behavioral Therapy by Disorder

    Case Studies and Application for Adults
    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    Pregnancy, childbirth, childhood, adolescence, and aging can be beset with adverse changes in psychobiology and behavior. Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging will better readers’ understanding of a variety of conditions and the applicability of CBT therapy as a treatment. Featuring chapters on postnatal anxiety and depression, insomnia, and dysmorphia, the book discusses in detail the use of cognitive behavioral therapies in the treatment of these issues affecting individuals at the start and end of their lives. With expert authors from the clinical field, the book has applicability for behavioral scientists, psychologists, cognitive and behavioral neuroscientists, and anyone working to better understand and treat using cognitive behavioral therapies.

  • Spinal Interneurons

    Plasticity after Spinal Cord Injury
    • 1st Edition
    • Lyandysha Viktorovna Zholudeva + 1 more
    • English
    The spinal cord is comprised of four types of neurons: motor neurons, pre-ganglionic neurons, ascending projection neurons, and spinal interneurons. Interneurons are neurons that process information within local circuits, and have an incredible ability for neuroplasticity, whether due to persistent activity, neural injury, or in response to disease. Although, by definition, their axons are restricted to the same structure as the soma (in this case the spinal cord), spinal interneurons are capable of sprouting and rewiring entire neural circuits, and contribute to some restoration of disrupted neural communication after injury to the spinal cord (i.e., “bypassing” the lesion site). Spinal Interneurons provides a focused overview of how scientists classify interneurons in general, the techniques used to identify subsets of interneurons, their roles in specific neural circuits, and the scientific evidence for their neuroplasticity. Understanding the capacity for neuroplasticity and identity of specific spinal interneurons that are optimal for recovery, may help determine cellular candidates for developing therapies. Spinal Interneurons provides neuroscientists, clinicians, and trainees a reference book exclusively concentrating on spinal interneurons, the techniques and experiments employed to identify and study these cells as part of normal and compromised neural circuits, and highlights the therapeutic potential of these cells by presenting the relevant pre-clinical and clinical work to date. People in industry will also benefit from this book, which compiles the latest in therapeutic strategies for targeting spinal interneurons, what considerations there are for the development and use of treatments, and how such treatments can not only be translated to the clinic, but how existing treatments should be appropriately reverse-translated to the bench.

  • Neurocircuitry of Addiction

    • 1st Edition
    • Nicholas W. Gilpin
    • English
    People use drugs for many different reasons, including the pursuit of "high," social factors and self-medication of other conditions. Many millions of people are addicted to at least one substance, and the cost of addiction is immense, at both the individual and societal levels. Neurocircuitry of Addiction is the first book of its kind, with a focus on addiction neuroscience from a neural circuit perspective. This book begins with a primer on circuit-based neuroscience that equips the reader with an understanding of the applications described throughout the book. Each subsequent chapter positions a different brain region at the "center" of addiction neurocircuitry and goes on to describe the anatomical connectivity of that brain region, how those circuits are affected by drug exposure, and the role of those circuits in controlling addiction-related behaviors. All chapters of this book are written by content experts for a target audience that has some basic neuroscience background, but no prior in-depth knowledge regarding the neurocircuitry of addiction.

  • Microbiome in Neurological Disease

    • 1st Edition
    • Volume 167
    • English
    Microbiome in Neurological Disease, Volume 167 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Section in this new release cover Intersections of the microbiome and early neurodevelopment, Microbiome influences on neuro-immune interactions, The genomes of Parkinson’s disease, Experimental contributions of the microbiome to Parkinson’s disease, The foundations of microbiome contributions to Alzheimer’s disease, Immunologic pathways by which the gut microbiota influences Alzheimer’s disease, Role of the gut microbiome in Huntington’s Disease, and much more.

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